PubMed:8522307
Annnotations
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1355-1358 | gene:7428 | denotes | VHL |
| T1 | 1472-1485 | disease:C0596263 | denotes | tumorigenesis |
| T2 | 1416-1419 | gene:7428 | denotes | VHL |
| T3 | 1472-1485 | disease:C0596263 | denotes | tumorigenesis |
| R1 | T0 | T1 | associated_with | VHL,tumorigenesis |
| R2 | T2 | T3 | associated_with | VHL,tumorigenesis |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 8522307-8#7#10#gene7428 | 1355-1358 | gene7428 | denotes | VHL |
| 8522307-8#68#71#gene7428 | 1416-1419 | gene7428 | denotes | VHL |
| 8522307-8#124#137#diseaseC0596263 | 1472-1485 | diseaseC0596263 | denotes | tumorigenesis |
| 8522307-8#150#162#diseaseC0010633 | 1498-1510 | diseaseC0010633 | denotes | cystadenomas |
| 8522307-8#124#137#diseaseC0596263 | 1472-1485 | diseaseC0596263 | denotes | tumorigenesis |
| 8522307-8#150#162#diseaseC0010633 | 1498-1510 | diseaseC0010633 | denotes | cystadenomas |
| 7#10#gene7428124#137#diseaseC0596263 | 8522307-8#7#10#gene7428 | 8522307-8#124#137#diseaseC0596263 | associated_with | VHL,tumorigenesis |
| 7#10#gene7428150#162#diseaseC0010633 | 8522307-8#7#10#gene7428 | 8522307-8#150#162#diseaseC0010633 | associated_with | VHL,cystadenomas |
| 7#10#gene7428124#137#diseaseC0596263 | 8522307-8#7#10#gene7428 | 8522307-8#124#137#diseaseC0596263 | associated_with | VHL,tumorigenesis |
| 7#10#gene7428150#162#diseaseC0010633 | 8522307-8#7#10#gene7428 | 8522307-8#150#162#diseaseC0010633 | associated_with | VHL,cystadenomas |
| 68#71#gene7428124#137#diseaseC0596263 | 8522307-8#68#71#gene7428 | 8522307-8#124#137#diseaseC0596263 | associated_with | VHL,tumorigenesis |
| 68#71#gene7428150#162#diseaseC0010633 | 8522307-8#68#71#gene7428 | 8522307-8#150#162#diseaseC0010633 | associated_with | VHL,cystadenomas |
| 68#71#gene7428124#137#diseaseC0596263 | 8522307-8#68#71#gene7428 | 8522307-8#124#137#diseaseC0596263 | associated_with | VHL,tumorigenesis |
| 68#71#gene7428150#162#diseaseC0010633 | 8522307-8#68#71#gene7428 | 8522307-8#150#162#diseaseC0010633 | associated_with | VHL,cystadenomas |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 78-88 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
| PD-UBERON-AE-B_T2 | 119-129 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
| PD-UBERON-AE-B_T3 | 449-459 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
| PD-UBERON-AE-B_T4 | 1518-1528 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-89 | Sentence | denotes | Somatic von Hippel-Lindau mutation in clear cell papillary cystadenoma of the epididymis. |
| TextSentencer_T2 | 90-244 | Sentence | denotes | Papillary cystadenoma of the epididymis is an uncommon benign lesion that may occur sporadically or as a manifestation of von Hippel-Lindau (VHL) disease. |
| TextSentencer_T3 | 245-374 | Sentence | denotes | Neither immunohistochemical studies nor molecular genetic analyses of the VHL gene have been reported previously for this lesion. |
| TextSentencer_T4 | 375-536 | Sentence | denotes | The authors describe two cases of clear cell papillary cystadenoma of the epididymis, both of which were initially confused with metastatic renal cell carcinoma. |
| TextSentencer_T5 | 537-734 | Sentence | denotes | Both lesions showed positive immunohistochemical staining for low and intermediate molecular weight keratins (Cam 5.2 and AE1/AE3), EMA, vimentin, alpha 1-antitrypsin, and alpha 1-antichymotrypsin. |
| TextSentencer_T6 | 735-761 | Sentence | denotes | Each was negative for CEA. |
| TextSentencer_T7 | 762-1011 | Sentence | denotes | Because clear cell papillary cystadenoma is similar to renal cell carcinoma histologically, and because both occur as components of the von Hippel-Lindau disease complex, the authors analyzed both cases for the presence of mutations in the VHL gene. |
| TextSentencer_T8 | 1012-1168 | Sentence | denotes | A somatic VHL gene mutation was detected in one of the two tumors by polymerase chain reaction followed by single-strand conformation polymorphism analysis. |
| TextSentencer_T9 | 1169-1347 | Sentence | denotes | Direct sequencing revealed a cytosine to thymine transition at nucleotide 694, resulting in the replacement of an arginine with a stop codon after the sixth amino acid of exon 3. |
| TextSentencer_T10 | 1348-1529 | Sentence | denotes | As the VHL gene is believed to function as a tumor suppressor gene, VHL gene mutations may play a role in the initiation of tumorigenesis in sporadic cystadenomas of the epididymis. |
| T1 | 0-89 | Sentence | denotes | Somatic von Hippel-Lindau mutation in clear cell papillary cystadenoma of the epididymis. |
| T2 | 90-244 | Sentence | denotes | Papillary cystadenoma of the epididymis is an uncommon benign lesion that may occur sporadically or as a manifestation of von Hippel-Lindau (VHL) disease. |
| T3 | 245-374 | Sentence | denotes | Neither immunohistochemical studies nor molecular genetic analyses of the VHL gene have been reported previously for this lesion. |
| T4 | 375-536 | Sentence | denotes | The authors describe two cases of clear cell papillary cystadenoma of the epididymis, both of which were initially confused with metastatic renal cell carcinoma. |
| T5 | 537-734 | Sentence | denotes | Both lesions showed positive immunohistochemical staining for low and intermediate molecular weight keratins (Cam 5.2 and AE1/AE3), EMA, vimentin, alpha 1-antitrypsin, and alpha 1-antichymotrypsin. |
| T6 | 735-761 | Sentence | denotes | Each was negative for CEA. |
| T7 | 762-1011 | Sentence | denotes | Because clear cell papillary cystadenoma is similar to renal cell carcinoma histologically, and because both occur as components of the von Hippel-Lindau disease complex, the authors analyzed both cases for the presence of mutations in the VHL gene. |
| T8 | 1012-1168 | Sentence | denotes | A somatic VHL gene mutation was detected in one of the two tumors by polymerase chain reaction followed by single-strand conformation polymorphism analysis. |
| T9 | 1169-1347 | Sentence | denotes | Direct sequencing revealed a cytosine to thymine transition at nucleotide 694, resulting in the replacement of an arginine with a stop codon after the sixth amino acid of exon 3. |
| T10 | 1348-1529 | Sentence | denotes | As the VHL gene is believed to function as a tumor suppressor gene, VHL gene mutations may play a role in the initiation of tumorigenesis in sporadic cystadenomas of the epididymis. |
PubCasesHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| AB1 | 90-129 | HP:0009715 | denotes | Papillary cystadenoma of the epididymis |
| TI1 | 49-88 | HP:0009715 | denotes | papillary cystadenoma of the epididymis |
| AB2 | 420-459 | HP:0009715 | denotes | papillary cystadenoma of the epididymis |
| AB3 | 515-535 | HP:0005584 | denotes | renal cell carcinoma |
| AB4 | 817-837 | HP:0005584 | denotes | renal cell carcinoma |
PubCasesORDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| AB1 | 231-234 | ORDO:892 | denotes | VHL |
| AB2 | 319-322 | ORDO:892 | denotes | VHL |
| AB3 | 898-923 | ORDO:892 | denotes | von Hippel-Lindau disease |
| AB4 | 1002-1005 | ORDO:892 | denotes | VHL |
| AB5 | 1022-1025 | ORDO:892 | denotes | VHL |
| AB6 | 1355-1358 | ORDO:892 | denotes | VHL |
| AB7 | 1416-1419 | ORDO:892 | denotes | VHL |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 78-88 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
| PD-UBERON-AE-B_T2 | 119-129 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
| PD-UBERON-AE-B_T3 | 449-459 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
| PD-UBERON-AE-B_T4 | 1518-1528 | http://purl.obolibrary.org/obo/UBERON_0001301 | denotes | epididymis |
NCBIDiseaseCorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 8-25 | Modifier:D006623 | denotes | von Hippel-Lindau |
| T2 | 49-88 | SpecificDisease:D018292 | denotes | papillary cystadenoma of the epididymis |
| T3 | 90-129 | SpecificDisease:D018292 | denotes | Papillary cystadenoma of the epididymis |
| T4 | 212-243 | SpecificDisease:D006623 | denotes | von Hippel-Lindau (VHL) disease |
| T5 | 319-322 | Modifier:D006623 | denotes | VHL |
| T6 | 420-459 | SpecificDisease:D018292 | denotes | papillary cystadenoma of the epididymis |
| T7 | 504-535 | SpecificDisease:C538445 | denotes | metastatic renal cell carcinoma |
| T8 | 781-802 | SpecificDisease:D018292 | denotes | papillary cystadenoma |
| T9 | 817-837 | SpecificDisease:D002292 | denotes | renal cell carcinoma |
| T10 | 898-923 | Modifier:D006623 | denotes | von Hippel-Lindau disease |
| T11 | 1002-1005 | Modifier:D006623 | denotes | VHL |
| T12 | 1022-1025 | Modifier:D006623 | denotes | VHL |
| T13 | 1071-1077 | DiseaseClass:D009369 | denotes | tumors |
| T14 | 1355-1358 | Modifier:D006623 | denotes | VHL |
| T15 | 1393-1398 | Modifier:D009369 | denotes | tumor |
| T16 | 1416-1419 | Modifier:D006623 | denotes | VHL |
| T17 | 1498-1528 | SpecificDisease:D003537 | denotes | cystadenomas of the epididymis |
NCBI-Disease-Train
| Id | Subject | Object | Predicate | Lexical cue | database_id |
|---|---|---|---|---|---|
| T2914 | 8-25 | Modifier | denotes | von Hippel-Lindau | D006623 |
| T2915 | 49-88 | SpecificDisease | denotes | papillary cystadenoma of the epididymis | D018292 |
| T2916 | 90-129 | SpecificDisease | denotes | Papillary cystadenoma of the epididymis | D018292 |
| T2917 | 212-243 | SpecificDisease | denotes | von Hippel-Lindau (VHL) disease | D006623 |
| T2918 | 319-322 | Modifier | denotes | VHL | D006623 |
| T2919 | 420-459 | SpecificDisease | denotes | papillary cystadenoma of the epididymis | D018292 |
| T2920 | 504-535 | SpecificDisease | denotes | metastatic renal cell carcinoma | C538445 |
| T2921 | 781-802 | SpecificDisease | denotes | papillary cystadenoma | D018292 |
| T2922 | 817-837 | SpecificDisease | denotes | renal cell carcinoma | D002292 |
| T2923 | 898-923 | Modifier | denotes | von Hippel-Lindau disease | D006623 |
| T2924 | 1002-1005 | Modifier | denotes | VHL | D006623 |
| T2925 | 1022-1025 | Modifier | denotes | VHL | D006623 |
| T2926 | 1071-1077 | DiseaseClass | denotes | tumors | D009369 |
| T2927 | 1355-1358 | Modifier | denotes | VHL | D006623 |
| T2928 | 1393-1398 | Modifier | denotes | tumor | D009369 |
| T2929 | 1416-1419 | Modifier | denotes | VHL | D006623 |
| T2930 | 1498-1528 | SpecificDisease | denotes | cystadenomas of the epididymis | D003537 |
NCBI-Disease-Corpus-All
| Id | Subject | Object | Predicate | Lexical cue | database_id |
|---|---|---|---|---|---|
| T2914 | 8-25 | Modifier | denotes | von Hippel-Lindau | D006623 |
| T2915 | 49-88 | SpecificDisease | denotes | papillary cystadenoma of the epididymis | D018292 |
| T2916 | 90-129 | SpecificDisease | denotes | Papillary cystadenoma of the epididymis | D018292 |
| T2917 | 212-243 | SpecificDisease | denotes | von Hippel-Lindau (VHL) disease | D006623 |
| T2918 | 319-322 | Modifier | denotes | VHL | D006623 |
| T2919 | 420-459 | SpecificDisease | denotes | papillary cystadenoma of the epididymis | D018292 |
| T2920 | 504-535 | SpecificDisease | denotes | metastatic renal cell carcinoma | C538445 |
| T2921 | 781-802 | SpecificDisease | denotes | papillary cystadenoma | D018292 |
| T2922 | 817-837 | SpecificDisease | denotes | renal cell carcinoma | D002292 |
| T2923 | 898-923 | Modifier | denotes | von Hippel-Lindau disease | D006623 |
| T2924 | 1002-1005 | Modifier | denotes | VHL | D006623 |
| T2925 | 1022-1025 | Modifier | denotes | VHL | D006623 |
| T2926 | 1071-1077 | DiseaseClass | denotes | tumors | D009369 |
| T2927 | 1355-1358 | Modifier | denotes | VHL | D006623 |
| T2928 | 1393-1398 | Modifier | denotes | tumor | D009369 |
| T2929 | 1416-1419 | Modifier | denotes | VHL | D006623 |
| T2930 | 1498-1528 | SpecificDisease | denotes | cystadenomas of the epididymis | D003537 |
NCBI-Disease-Corpus-2stage-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 38-70 | SpecificDisease | denotes | clear cell papillary cystadenoma |
| T2 | 90-129 | SpecificDisease | denotes | Papillary cystadenoma of the epididymis |
| T3 | 212-243 | SpecificDisease | denotes | von Hippel-Lindau (VHL) disease |
| T4 | 319-327 | Modifier | denotes | VHL gene |
| T5 | 409-459 | SpecificDisease | denotes | clear cell papillary cystadenoma of the epididymis |
| T6 | 515-535 | SpecificDisease | denotes | renal cell carcinoma |
| T7 | 770-802 | SpecificDisease | denotes | clear cell papillary cystadenoma |
| T8 | 817-837 | SpecificDisease | denotes | renal cell carcinoma |
| T9 | 898-923 | SpecificDisease | denotes | von Hippel-Lindau disease |
| T10 | 1002-1010 | Modifier | denotes | VHL gene |
| T11 | 1022-1030 | Modifier | denotes | VHL gene |
| T12 | 1355-1363 | Modifier | denotes | VHL gene |
| T13 | 1416-1424 | Modifier | denotes | VHL gene |
| T14 | 1498-1528 | SpecificDisease | denotes | cystadenomas of the epididymis |
NCBI-Disease-Corpus-rezarta-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 8-25 | Modifier | denotes | von Hippel-Lindau |
| T2 | 212-229 | SpecificDisease | denotes | von Hippel-Lindau |
| T3 | 231-234 | SpecificDisease | denotes | VHL |
| T4 | 319-322 | Modifier | denotes | VHL |
| T5 | 515-535 | SpecificDisease | denotes | renal cell carcinoma |
| T6 | 817-837 | SpecificDisease | denotes | renal cell carcinoma |
| T7 | 898-923 | SpecificDisease | denotes | von Hippel-Lindau disease |
| T8 | 1002-1005 | Modifier | denotes | VHL |
| T9 | 1022-1025 | Modifier | denotes | VHL |
| T10 | 1355-1358 | Modifier | denotes | VHL |
| T11 | 1416-1419 | Modifier | denotes | VHL |
NCBI-Disease-Corpus-4oGuideline-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 38-70 | SpecificDisease | denotes | clear cell papillary cystadenoma |
| T2 | 90-129 | SpecificDisease | denotes | Papillary cystadenoma of the epididymis |
| T3 | 212-243 | SpecificDisease | denotes | von Hippel-Lindau (VHL) disease |
| T4 | 409-459 | SpecificDisease | denotes | clear cell papillary cystadenoma of the epididymis |
| T5 | 504-535 | SpecificDisease | denotes | metastatic renal cell carcinoma |
| T6 | 770-802 | SpecificDisease | denotes | clear cell papillary cystadenoma |
| T7 | 817-837 | SpecificDisease | denotes | renal cell carcinoma |
| T8 | 898-923 | SpecificDisease | denotes | von Hippel-Lindau disease |
| T9 | 1498-1528 | SpecificDisease | denotes | cystadenomas of the epididymis |
NCBI-Disease-Corpus-Simple-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 38-88 | SpecificDisease | denotes | clear cell papillary cystadenoma of the epididymis |
| T2 | 90-129 | SpecificDisease | denotes | Papillary cystadenoma of the epididymis |
| T3 | 212-243 | SpecificDisease | denotes | von Hippel-Lindau (VHL) disease |
| T4 | 319-322 | SpecificDisease | denotes | VHL |
| T5 | 409-459 | SpecificDisease | denotes | clear cell papillary cystadenoma of the epididymis |
| T6 | 504-535 | SpecificDisease | denotes | metastatic renal cell carcinoma |
| T7 | 770-802 | SpecificDisease | denotes | clear cell papillary cystadenoma |
| T8 | 817-837 | SpecificDisease | denotes | renal cell carcinoma |
| T9 | 898-923 | SpecificDisease | denotes | von Hippel-Lindau disease |
| T10 | 1002-1005 | SpecificDisease | denotes | VHL |
| T11 | 1022-1025 | SpecificDisease | denotes | VHL |
| T12 | 1355-1358 | SpecificDisease | denotes | VHL |
| T13 | 1393-1414 | Modifier | denotes | tumor suppressor gene |
| T14 | 1416-1419 | SpecificDisease | denotes | VHL |
| T15 | 1489-1528 | SpecificDisease | denotes | sporadic cystadenomas of the epididymis |