PubMed:8466512 JSONTXT

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":88},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":89,"end":357},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":358,"end":603},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":88},"obj":"Sentence"},{"id":"T2","span":{"begin":89,"end":357},"obj":"Sentence"},{"id":"T3","span":{"begin":358,"end":603},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"PubCasesORDO","denotations":[{"id":"AB1","span":{"begin":435,"end":451},"obj":"ORDO:26793"}],"namespaces":[{"prefix":"ORDO","uri":"http://www.orpha.net/ORDO/Orphanet_"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBIDiseaseCorpus","denotations":[{"id":"T1","span":{"begin":21,"end":87},"obj":"SpecificDisease:C536353"},{"id":"T2","span":{"begin":435,"end":451},"obj":"SpecificDisease:C536353"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBI-Disease-Train","denotations":[{"id":"T2241","span":{"begin":21,"end":87},"obj":"SpecificDisease"},{"id":"T2242","span":{"begin":435,"end":451},"obj":"SpecificDisease"}],"attributes":[{"id":"A2241","pred":"database_id","subj":"T2241","obj":"C536353"},{"id":"A2242","pred":"database_id","subj":"T2242","obj":"C536353"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBI-Disease-Corpus-All","denotations":[{"id":"T2241","span":{"begin":21,"end":87},"obj":"SpecificDisease"},{"id":"T2242","span":{"begin":435,"end":451},"obj":"SpecificDisease"}],"attributes":[{"id":"A2241","pred":"database_id","subj":"T2241","obj":"C536353"},{"id":"A2242","pred":"database_id","subj":"T2242","obj":"C536353"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBI-Disease-Corpus-2stage-All","denotations":[{"id":"T1","span":{"begin":8,"end":15},"obj":"DiseaseClass"},{"id":"T2","span":{"begin":350,"end":355},"obj":"Modifier"},{"id":"T3","span":{"begin":426,"end":433},"obj":"DiseaseClass"},{"id":"T4","span":{"begin":435,"end":451},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":597,"end":602},"obj":"SpecificDisease"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBI-Disease-Corpus-rezarta-All","denotations":[{"id":"T1","span":{"begin":49,"end":87},"obj":"DiseaseClass"},{"id":"T2","span":{"begin":279,"end":291},"obj":"Modifier"},{"id":"T3","span":{"begin":293,"end":303},"obj":"Modifier"},{"id":"T4","span":{"begin":309,"end":348},"obj":"Modifier"},{"id":"T5","span":{"begin":350,"end":355},"obj":"Modifier"},{"id":"T6","span":{"begin":435,"end":451},"obj":"SpecificDisease"},{"id":"T7","span":{"begin":597,"end":602},"obj":"Modifier"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBI-Disease-Corpus-4oGuideline-All","denotations":[{"id":"T1","span":{"begin":8,"end":15},"obj":"DiseaseClass"},{"id":"T2","span":{"begin":21,"end":87},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":195,"end":215},"obj":"DiseaseClass"},{"id":"T4","span":{"begin":309,"end":356},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":426,"end":451},"obj":"SpecificDisease"},{"id":"T6","span":{"begin":597,"end":602},"obj":"SpecificDisease"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}

{"project":"NCBI-Disease-Corpus-Simple-All","denotations":[{"id":"T1","span":{"begin":8,"end":87},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":350,"end":355},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":426,"end":451},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":597,"end":602},"obj":"SpecificDisease"}],"text":"A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase.\nPalmitoyl-CoA dehydrogenase activity in skin fibroblasts from seven patients with unidentified defects of fatty acid oxidation was measured in the presence and absence of antibodies against medium-chain, long-chain, and very-long-chain acyl-CoA dehydrogenases (VLCAD). Two of the patients, 4-5 month old boys, were found to have a novel disease, VLCAD deficiency, as judged from the results of very low palmitoyl-CoA dehydrogenase activity and the lack of immunoreactivity toward antibody raised to purified VLCAD."}