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sentences

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Transcriptional regulation of interleukin 3 (IL3) in primary human T lymphocytes.
T2 82-159 Sentence denotes Role of AP-1- and octamer-binding proteins in control of IL3 gene expression.
T3 160-418 Sentence denotes We have investigated the molecular and biochemical basis for activation of interleukin 3 (IL3) gene expression in primary human T lymphocytes following CD3 and CD2 receptor stimulation or activation by phytohemagglutinin plus phorbol 12-myristate 13-acetate.
T4 419-822 Sentence denotes Using transfection and reporter gene assays specifically designed for primary T lymphocytes in conjunction with gel retardation assays, Western blot analyses and UV cross-linking studies, we found that c-Jun, c-Fos, and octamer-binding proteins play a major role in transcriptional activation of the IL3 gene via their interaction with two specific regions contained within the IL3 5'-flanking sequence.
T5 823-1004 Sentence denotes Additionally, the region between bases -107 and -59 of the IL3 promoter containing putative AP-2 and Sp1 binding motifs appears necessary for basal level expression of the IL3 gene.
T6 1005-1215 Sentence denotes The data also indicate that CD2 receptor activation and phytohemagglutinin plus phorbol 12-myristate 13-acetate stimulation augment T cell IL3 gene expression through the same cis- and trans-activating signals.
T7 1216-1338 Sentence denotes These results should contribute to a better understanding of the regulation of IL3 gene expression in human T lymphocytes.
T1 0-81 Sentence denotes Transcriptional regulation of interleukin 3 (IL3) in primary human T lymphocytes.
T2 82-159 Sentence denotes Role of AP-1- and octamer-binding proteins in control of IL3 gene expression.
T3 160-418 Sentence denotes We have investigated the molecular and biochemical basis for activation of interleukin 3 (IL3) gene expression in primary human T lymphocytes following CD3 and CD2 receptor stimulation or activation by phytohemagglutinin plus phorbol 12-myristate 13-acetate.
T4 419-822 Sentence denotes Using transfection and reporter gene assays specifically designed for primary T lymphocytes in conjunction with gel retardation assays, Western blot analyses and UV cross-linking studies, we found that c-Jun, c-Fos, and octamer-binding proteins play a major role in transcriptional activation of the IL3 gene via their interaction with two specific regions contained within the IL3 5'-flanking sequence.
T5 823-1004 Sentence denotes Additionally, the region between bases -107 and -59 of the IL3 promoter containing putative AP-2 and Sp1 binding motifs appears necessary for basal level expression of the IL3 gene.
T6 1005-1215 Sentence denotes The data also indicate that CD2 receptor activation and phytohemagglutinin plus phorbol 12-myristate 13-acetate stimulation augment T cell IL3 gene expression through the same cis- and trans-activating signals.
T7 1216-1338 Sentence denotes These results should contribute to a better understanding of the regulation of IL3 gene expression in human T lymphocytes.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 30-43 protein denotes interleukin 3
T2 45-48 protein denotes IL3
T3 53-80 cell_type denotes primary human T lymphocytes
T4 90-124 protein denotes AP-1- and octamer-binding proteins
T5 139-142 protein denotes IL3
T6 235-248 protein denotes interleukin 3
T7 250-253 protein denotes IL3
T8 274-301 cell_type denotes primary human T lymphocytes
T9 362-380 protein denotes phytohemagglutinin
T10 489-510 cell_type denotes primary T lymphocytes
T11 621-626 protein denotes c-Jun
T12 628-633 protein denotes c-Fos
T13 639-663 protein denotes octamer-binding proteins
T14 719-727 DNA denotes IL3 gene
T15 797-821 DNA denotes IL3 5'-flanking sequence
T16 862-874 DNA denotes -107 and -59
T17 882-894 DNA denotes IL3 promoter
T18 915-942 DNA denotes AP-2 and Sp1 binding motifs
T19 995-998 protein denotes IL3
T20 1033-1036 protein denotes CD2
T21 1061-1079 protein denotes phytohemagglutinin
T22 1144-1147 protein denotes IL3
T23 1295-1298 protein denotes IL3
T24 1318-1337 cell_type denotes human T lymphocytes

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-81 Sentence denotes Transcriptional regulation of interleukin 3 (IL3) in primary human T lymphocytes.
S2 82-159 Sentence denotes Role of AP-1- and octamer-binding proteins in control of IL3 gene expression.
S3 160-418 Sentence denotes We have investigated the molecular and biochemical basis for activation of interleukin 3 (IL3) gene expression in primary human T lymphocytes following CD3 and CD2 receptor stimulation or activation by phytohemagglutinin plus phorbol 12-myristate 13-acetate.
S4 419-822 Sentence denotes Using transfection and reporter gene assays specifically designed for primary T lymphocytes in conjunction with gel retardation assays, Western blot analyses and UV cross-linking studies, we found that c-Jun, c-Fos, and octamer-binding proteins play a major role in transcriptional activation of the IL3 gene via their interaction with two specific regions contained within the IL3 5'-flanking sequence.
S5 823-1004 Sentence denotes Additionally, the region between bases -107 and -59 of the IL3 promoter containing putative AP-2 and Sp1 binding motifs appears necessary for basal level expression of the IL3 gene.
S6 1005-1215 Sentence denotes The data also indicate that CD2 receptor activation and phytohemagglutinin plus phorbol 12-myristate 13-acetate stimulation augment T cell IL3 gene expression through the same cis- and trans-activating signals.
S7 1216-1338 Sentence denotes These results should contribute to a better understanding of the regulation of IL3 gene expression in human T lymphocytes.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 30-49 NP denotes interleukin 3 (IL3)
C3 53-80 NP denotes primary human T lymphocytes
C1 0-80 NP denotes Transcriptional regulation of interleukin 3 (IL3) in primary human T lymphocytes
C4 139-142 NP denotes IL3
C7 235-254 NP denotes interleukin 3 (IL3)
C6 235-270 NP denotes interleukin 3 (IL3) gene expression
C8 274-301 NP denotes primary human T lymphocytes
C5 221-301 NP denotes activation of interleukin 3 (IL3) gene expression in primary human T lymphocytes
C9 320-332 NP denotes CD2 receptor
C10 362-417 NP denotes phytohemagglutinin plus phorbol 12-myristate 13-acetate
C11 489-510 NP denotes primary T lymphocytes
C13 715-727 NP denotes the IL3 gene
C12 685-727 NP denotes transcriptional activation of the IL3 gene
C14 797-800 NP denotes IL3
C15 882-885 NP denotes IL3
C16 991-1003 NP denotes the IL3 gene
C17 1033-1045 NP denotes CD2 receptor
C18 1061-1116 NP denotes phytohemagglutinin plus phorbol 12-myristate 13-acetate
C20 1144-1147 NP denotes IL3
C19 1137-1163 NP denotes T cell IL3 gene expression
C23 1295-1298 NP denotes IL3
C24 1318-1337 NP denotes human T lymphocytes
C22 1295-1337 NP denotes IL3 gene expression in human T lymphocytes
C21 1277-1337 NP denotes the regulation of IL3 gene expression in human T lymphocytes
R1 C4 C2 coref-ident IL3,interleukin 3 (IL3)
R2 C6 C4 coref-ident interleukin 3 (IL3) gene expression,IL3
R3 C8 C3 coref-ident primary human T lymphocytes,primary human T lymphocytes
R4 C11 C8 coref-ident primary T lymphocytes,primary human T lymphocytes
R5 C13 C6 coref-ident the IL3 gene,interleukin 3 (IL3) gene expression
R6 C12 C5 coref-ident transcriptional activation of the IL3 gene,activation of interleukin 3 (IL3) gene expression in primary human T lymphocytes
R7 C14 C13 coref-ident IL3,the IL3 gene
R8 C15 C14 coref-ident IL3,IL3
R9 C16 C13 coref-ident the IL3 gene,the IL3 gene
R10 C17 C9 coref-ident CD2 receptor,CD2 receptor
R11 C18 C10 coref-ident phytohemagglutinin plus phorbol 12-myristate 13-acetate,phytohemagglutinin plus phorbol 12-myristate 13-acetate
R12 C20 C15 coref-ident IL3,IL3
R13 C19 C7 coref-ident T cell IL3 gene expression,interleukin 3 (IL3)
R14 C23 C20 coref-ident IL3,IL3
R15 C24 C11 coref-ident human T lymphocytes,primary T lymphocytes
R16 C22 C19 coref-ident IL3 gene expression in human T lymphocytes,T cell IL3 gene expression
R17 C21 C1 coref-ident the regulation of IL3 gene expression in human T lymphocytes,Transcriptional regulation of interleukin 3 (IL3) in primary human T lymphocytes

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-26 other_name denotes Transcriptional regulation
T2 30-43 protein_molecule denotes interleukin 3
T3 45-48 protein_molecule denotes IL3
T4 53-80 cell_type denotes primary human T lymphocytes
T5 139-142 protein_molecule denotes IL3
T6 235-248 protein_molecule denotes interleukin 3
T7 250-253 protein_molecule denotes IL3
T8 274-301 cell_type denotes primary human T lymphocytes
T9 362-380 protein_molecule denotes phytohemagglutinin
T10 386-417 other_organic_compound denotes phorbol 12-myristate 13-acetate
T11 489-510 cell_type denotes primary T lymphocytes
T12 531-553 other_name denotes gel retardation assays
T13 555-576 other_name denotes Western blot analyses
T14 581-605 other_name denotes UV cross-linking studies
T15 621-626 protein_molecule denotes c-Jun
T16 628-633 protein_molecule denotes c-Fos
T17 639-663 protein_family_or_group denotes octamer-binding proteins
T18 685-711 other_name denotes transcriptional activation
T19 719-722 protein_molecule denotes IL3
T20 797-800 protein_molecule denotes IL3
T21 862-874 DNA_domain_or_region denotes -107 and -59
T22 882-885 protein_molecule denotes IL3
T23 965-987 other_name denotes basal level expression
T24 995-998 protein_molecule denotes IL3
T25 1033-1036 protein_molecule denotes CD2
T26 1061-1079 protein_molecule denotes phytohemagglutinin
T27 1085-1116 other_organic_compound denotes phorbol 12-myristate 13-acetate
T28 1137-1143 other_name denotes T cell
T29 1144-1147 protein_molecule denotes IL3
T30 1181-1215 other_name denotes cis- and trans-activating signals.
T31 1295-1298 protein_molecule denotes IL3
T32 1318-1337 cell_type denotes human T lymphocytes

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 61-66 OrganismTaxon denotes human 9606
T2 282-287 OrganismTaxon denotes human 9606
T3 1318-1323 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 67-80 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T2 288-301 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T3 497-510 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T4 1137-1143 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T5 1324-1337 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 67-80 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T2 288-301 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T3 497-510 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T4 965-970 Cell denotes basal http://purl.obolibrary.org/obo/CL:0002324
T5 1137-1143 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T6 1324-1337 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084