
PubMed:8422459
Annnotations
jnlpba-st-training
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-13 | protein | denotes | Interleukin-4 |
T2 | 68-97 | RNA | denotes | c-jun and c-fos messenger RNA |
T3 | 102-121 | protein | denotes | activator protein-1 |
T4 | 142-157 | cell_type | denotes | human monocytes |
T5 | 184-197 | protein | denotes | interleukin-4 |
T6 | 199-203 | protein | denotes | IL-4 |
T7 | 276-281 | DNA | denotes | c-fos |
T8 | 286-291 | DNA | denotes | c-jun |
T9 | 335-350 | protein | denotes | dimeric complex |
T10 | 351-370 | protein | denotes | activator protein-1 |
T11 | 372-376 | protein | denotes | AP-1 |
T12 | 400-422 | protein | denotes | transcriptional factor |
T13 | 455-484 | RNA | denotes | c-fos and c-jun messenger RNA |
T14 | 561-565 | protein | denotes | IL-4 |
T15 | 679-684 | DNA | denotes | c-fos |
T16 | 709-713 | protein | denotes | IL-4 |
T17 | 717-734 | cell_type | denotes | LPS-treated cells |
T18 | 792-813 | DNA | denotes | c-fos and c-jun genes |
T19 | 815-819 | protein | denotes | IL-4 |
T20 | 856-861 | protein | denotes | c-fos |
T21 | 866-883 | protein | denotes | c-jun transcripts |
T22 | 966-970 | protein | denotes | IL-4 |
T23 | 1006-1010 | protein | denotes | AP-1 |
T24 | 1045-1049 | protein | denotes | IL-4 |
T25 | 1078-1099 | protein | denotes | transcription factors |
T26 | 1103-1128 | cell_type | denotes | human activated monocytes |
pubmed-sentences-benchmark
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
S1 | 0-158 | Sentence | denotes | Interleukin-4 inhibits the lipopolysaccharide-induced expression of c-jun and c-fos messenger RNA and activator protein-1 binding activity in human monocytes. |
S2 | 159-292 | Sentence | denotes | We studied the effect of interleukin-4 (IL-4) on the lipopolysaccharide (LPS) induction of two immediate early genes c-fos and c-jun. |
S3 | 293-423 | Sentence | denotes | These genes encode proteins that form the dimeric complex activator protein-1 (AP-1), which is active as a transcriptional factor. |
S4 | 424-531 | Sentence | denotes | Maximal accumulation of either c-fos and c-jun messenger RNA (mRNA) occurred 30 minutes after LPS addition. |
S5 | 532-660 | Sentence | denotes | When cells were treated with IL-4 for 5 hours before LPS activation, both the c-fos and the c-jun mRNA expression was decreased. |
S6 | 661-814 | Sentence | denotes | The inhibition of c-fos and c-jun expression by IL-4 in LPS-treated cells was shown to be due to a lower transcription rate of the c-fos and c-jun genes. |
S7 | 815-884 | Sentence | denotes | IL-4 did not affect the stability of the c-fos and c-jun transcripts. |
S8 | 885-1019 | Sentence | denotes | Finally, using electrophoretic mobility shift assays, evidence was obtained that IL-4 inhibits LPS-induced expression of AP-1 protein. |
S9 | 1020-1129 | Sentence | denotes | These data indicate that IL-4 suppresses the induction of transcription factors in human activated monocytes. |
genia-medco-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
C1 | 0-13 | NP | denotes | Interleukin-4 |
C3 | 68-83 | NP | denotes | c-jun and c-fos |
C2 | 68-97 | NP | denotes | c-jun and c-fos messenger RNA |
C4 | 102-121 | NP | denotes | activator protein-1 |
C5 | 142-157 | NP | denotes | human monocytes |
C6 | 184-204 | NP | denotes | interleukin-4 (IL-4) |
C7 | 212-236 | NP | denotes | lipopolysaccharide (LPS) |
C8 | 250-291 | NP | denotes | two immediate early genes c-fos and c-jun |
C9 | 293-304 | NP | denotes | These genes |
C10 | 312-320 | NP | denotes | proteins |
C11 | 321-325 | NP | denotes | that |
C12 | 331-377 | NP | denotes | the dimeric complex activator protein-1 (AP-1) |
C13 | 379-384 | NP | denotes | which |
C15 | 455-470 | NP | denotes | c-fos and c-jun |
C14 | 455-491 | NP | denotes | c-fos and c-jun messenger RNA (mRNA) |
C16 | 518-521 | NP | denotes | LPS |
C17 | 537-542 | NP | denotes | cells |
C18 | 561-565 | NP | denotes | IL-4 |
C19 | 585-588 | NP | denotes | LPS |
C21 | 610-629 | NP | denotes | c-fos and the c-jun |
C20 | 601-634 | NP | denotes | both the c-fos and the c-jun mRNA |
C22 | 679-694 | NP | denotes | c-fos and c-jun |
C23 | 709-713 | NP | denotes | IL-4 |
C24 | 717-734 | NP | denotes | LPS-treated cells |
C25 | 788-813 | NP | denotes | the c-fos and c-jun genes |
C26 | 815-819 | NP | denotes | IL-4 |
C27 | 856-871 | NP | denotes | c-fos and c-jun |
C28 | 966-970 | NP | denotes | IL-4 |
C29 | 1006-1018 | NP | denotes | AP-1 protein |
C30 | 1045-1049 | NP | denotes | IL-4 |
C31 | 1103-1128 | NP | denotes | human activated monocytes |
R1 | C6 | C1 | coref-ident | interleukin-4 (IL-4),Interleukin-4 |
R2 | C8 | C3 | coref-ident | two immediate early genes c-fos and c-jun,c-jun and c-fos |
R3 | C9 | C8 | coref-ident | These genes,two immediate early genes c-fos and c-jun |
R4 | C11 | C10 | coref-relat | that,proteins |
R5 | C12 | C4 | coref-ident | the dimeric complex activator protein-1 (AP-1),activator protein-1 |
R6 | C13 | C12 | coref-relat | which,the dimeric complex activator protein-1 (AP-1) |
R7 | C15 | C9 | coref-ident | c-fos and c-jun,These genes |
R8 | C14 | C2 | coref-other | c-fos and c-jun messenger RNA (mRNA),c-jun and c-fos messenger RNA |
R9 | C16 | C7 | coref-ident | LPS,lipopolysaccharide (LPS) |
R10 | C18 | C6 | coref-ident | IL-4,interleukin-4 (IL-4) |
R11 | C19 | C16 | coref-ident | LPS,LPS |
R12 | C21 | C15 | coref-ident | c-fos and the c-jun,c-fos and c-jun |
R13 | C20 | C14 | coref-ident | both the c-fos and the c-jun mRNA,c-fos and c-jun messenger RNA (mRNA) |
R14 | C22 | C21 | coref-ident | c-fos and c-jun,c-fos and the c-jun |
R15 | C23 | C18 | coref-ident | IL-4,IL-4 |
R16 | C24 | C23 | coref-other | LPS-treated cells,IL-4 |
R17 | C25 | C22 | coref-ident | the c-fos and c-jun genes,c-fos and c-jun |
R18 | C26 | C23 | coref-ident | IL-4,IL-4 |
R19 | C27 | C25 | coref-ident | c-fos and c-jun,the c-fos and c-jun genes |
R20 | C28 | C26 | coref-ident | IL-4,IL-4 |
R21 | C29 | C12 | coref-ident | AP-1 protein,the dimeric complex activator protein-1 (AP-1) |
R22 | C30 | C28 | coref-ident | IL-4,IL-4 |
R23 | C31 | C5 | coref-other | human activated monocytes,human monocytes |
GENIAcorpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-13 | protein_molecule | denotes | Interleukin-4 |
T2 | 102-121 | protein_molecule | denotes | activator protein-1 |
T3 | 142-157 | cell_type | denotes | human monocytes |
T4 | 184-197 | protein_molecule | denotes | interleukin-4 |
T5 | 199-203 | protein_molecule | denotes | IL-4 |
T6 | 232-235 | lipid | denotes | LPS |
T7 | 276-281 | DNA_domain_or_region | denotes | c-fos |
T8 | 286-291 | DNA_domain_or_region | denotes | c-jun |
T9 | 335-350 | protein_complex | denotes | dimeric complex |
T10 | 351-370 | protein_complex | denotes | activator protein-1 |
T11 | 372-376 | protein_complex | denotes | AP-1 |
T12 | 400-422 | protein_family_or_group | denotes | transcriptional factor |
T13 | 518-521 | lipid | denotes | LPS |
T14 | 561-565 | protein_molecule | denotes | IL-4 |
T15 | 585-588 | lipid | denotes | LPS |
T16 | 679-684 | DNA_domain_or_region | denotes | c-fos |
T17 | 709-713 | protein_molecule | denotes | IL-4 |
T18 | 717-734 | cell_type | denotes | LPS-treated cells |
T19 | 792-797 | DNA_domain_or_region | denotes | c-fos |
T20 | 802-813 | DNA_domain_or_region | denotes | c-jun genes |
T21 | 815-819 | protein_molecule | denotes | IL-4 |
T22 | 856-861 | protein_family_or_group | denotes | c-fos |
T23 | 866-883 | protein_family_or_group | denotes | c-jun transcripts |
T24 | 900-937 | other_name | denotes | electrophoretic mobility shift assays |
T25 | 966-970 | protein_molecule | denotes | IL-4 |
T26 | 980-1002 | other_name | denotes | LPS-induced expression |
T27 | 1006-1010 | protein_complex | denotes | AP-1 |
T28 | 1045-1049 | protein_molecule | denotes | IL-4 |
T29 | 1078-1099 | protein_family_or_group | denotes | transcription factors |
T30 | 1103-1118 | cell_type | denotes | human activated |
T31 | 1119-1128 | cell_type | denotes | monocytes |