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PubMed:8419931 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 93-109 protein denotes protein kinase C
T2 131-160 cell_type denotes human B-lymphocyte precursors
T3 202-231 cell_type denotes human B-lymphocyte precursors
T4 271-294 protein denotes protein-tyrosine kinase
T5 331-354 cell_type denotes B-lymphocyte precursors
T6 507-538 protein denotes serine-specific protein kinases
T7 550-566 protein denotes protein kinase C
T8 592-614 protein denotes nuclear factor kappa B
T9 687-748 protein denotes protein-tyrosine kinase inhibitors genistein and herbimycin A
T10 858-874 protein denotes protein kinase C
T11 896-925 cell_type denotes human B-lymphocyte precursors

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-161 Sentence denotes Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.
S2 162-314 Sentence denotes Ionizing radiation triggers a signal in human B-lymphocyte precursors that is intimately linked to an active protein-tyrosine kinase regulatory pathway.
S3 315-615 Sentence denotes We show that in B-lymphocyte precursors, irradiation with gamma-rays leads to (i) stimulation of phosphatidylinositol turnover; (ii) downstream activation by covalent modification of multiple serine-specific protein kinases, including protein kinase C; and (iii) activation of nuclear factor kappa B.
S4 616-749 Sentence denotes All of the radiation-induced signals were effectively prevented by the protein-tyrosine kinase inhibitors genistein and herbimycin A.
S5 750-926 Sentence denotes Thus, tyrosine phosphorylation is an important and perhaps mandatory proximal step in the activation of the protein kinase C signaling cascade in human B-lymphocyte precursors.
S6 927-1094 Sentence denotes Our report expands current knowledge of the radiation-induced signaling cascade by clarifying the chronological sequence of biochemical events that follow irradiation.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-24 NP denotes Tyrosine phosphorylation
C3 89-127 NP denotes the protein kinase C signaling pathway
C4 131-160 NP denotes human B-lymphocyte precursors
C2 57-160 NP denotes radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors
C6 202-231 NP denotes human B-lymphocyte precursors
C5 190-231 NP denotes a signal in human B-lymphocyte precursors
C7 232-236 NP denotes that
C8 261-313 NP denotes an active protein-tyrosine kinase regulatory pathway
C9 331-354 NP denotes B-lymphocyte precursors
C10 756-780 NP denotes tyrosine phosphorylation
C12 896-925 NP denotes human B-lymphocyte precursors
C11 836-925 NP denotes the activation of the protein kinase C signaling cascade in human B-lymphocyte precursors
C13 1021-1069 NP denotes the chronological sequence of biochemical events
C14 1070-1074 NP denotes that
R1 C6 C4 coref-ident human B-lymphocyte precursors,human B-lymphocyte precursors
R2 C7 C5 coref-relat that,a signal in human B-lymphocyte precursors
R3 C8 C3 coref-ident an active protein-tyrosine kinase regulatory pathway,the protein kinase C signaling pathway
R4 C9 C6 coref-ident B-lymphocyte precursors,human B-lymphocyte precursors
R5 C10 C1 coref-ident tyrosine phosphorylation,Tyrosine phosphorylation
R6 C12 C9 coref-ident human B-lymphocyte precursors,B-lymphocyte precursors
R7 C11 C2 coref-ident the activation of the protein kinase C signaling cascade in human B-lymphocyte precursors,radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors
R8 C14 C13 coref-relat that,the chronological sequence of biochemical events

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-8 amino_acid_monomer denotes Tyrosine
T2 30-53 other_name denotes mandatory proximal step
T3 57-85 other_name denotes radiation-induced activation
T4 93-109 protein_molecule denotes protein kinase C
T5 131-136 multi_cell denotes human
T6 162-180 other_name denotes Ionizing radiation
T7 202-207 multi_cell denotes human
T8 264-270 other_name denotes active
T9 271-294 protein_family_or_group denotes protein-tyrosine kinase
T10 331-354 cell_type denotes B-lymphocyte precursors
T11 356-367 other_name denotes irradiation
T12 373-383 other_name denotes gamma-rays
T13 412-432 lipid denotes phosphatidylinositol
T14 507-538 protein_family_or_group denotes serine-specific protein kinases
T15 550-566 protein_family_or_group denotes protein kinase C
T16 592-614 protein_family_or_group denotes nuclear factor kappa B
T17 627-652 other_name denotes radiation-induced signals
T18 687-710 protein_family_or_group denotes protein-tyrosine kinase
T19 756-764 amino_acid_monomer denotes tyrosine
T20 858-874 protein_family_or_group denotes protein kinase C
T21 896-925 cell_type denotes human B-lymphocyte precursors
T22 971-1006 other_name denotes radiation-induced signaling cascade
T23 1082-1093 other_name denotes irradiation