PubMed:8376399 / 2537-2864 JSONTXT

{"project":"sentences","denotations":[{"id":"T16","span":{"begin":0,"end":327},"obj":"Sentence"},{"id":"T16","span":{"begin":0,"end":327},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T19","span":{"begin":78,"end":91},"obj":"http://purl.obolibrary.org/obo/MAT_0000303"},{"id":"T20","span":{"begin":85,"end":91},"obj":"http://purl.obolibrary.org/obo/MAT_0000025"},{"id":"T21","span":{"begin":266,"end":274},"obj":"http://purl.obolibrary.org/obo/MAT_0000034"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"Anatomy-MAT","denotations":[{"id":"T10","span":{"begin":78,"end":91},"obj":"Body_part"},{"id":"T11","span":{"begin":266,"end":274},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"mat_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MAT_0000303"},{"id":"A11","pred":"mat_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MAT_0000034"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"HP-phenotype","denotations":[{"id":"T4","span":{"begin":307,"end":316},"obj":"Phenotype"}],"attributes":[{"id":"A4","pred":"hp_id","subj":"T4","obj":"HP:0003651"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"GlyCosmos15-HP","denotations":[{"id":"T4","span":{"begin":307,"end":316},"obj":"Phenotype"}],"attributes":[{"id":"A4","pred":"hp_id","subj":"T4","obj":"HP:0003651"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"GlyCosmos15-CL","denotations":[{"id":"T24","span":{"begin":78,"end":97},"obj":"Cell"},{"id":"T25","span":{"begin":296,"end":306},"obj":"Cell"},{"id":"T27","span":{"begin":307,"end":316},"obj":"Cell"}],"attributes":[{"id":"A24","pred":"cl_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CL:0000192"},{"id":"A25","pred":"cl_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CL:0000235"},{"id":"A26","pred":"cl_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CL:0000394"},{"id":"A27","pred":"cl_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CL:0000891"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T20","span":{"begin":78,"end":97},"obj":"Body_part"},{"id":"T21","span":{"begin":99,"end":119},"obj":"Body_part"},{"id":"T22","span":{"begin":266,"end":279},"obj":"Body_part"},{"id":"T23","span":{"begin":296,"end":306},"obj":"Body_part"}],"attributes":[{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL_0000192"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/GO_0031012"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0000415"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CL_0000235"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"GlyCosmos15-MAT","denotations":[{"id":"T10","span":{"begin":78,"end":91},"obj":"Body_part"},{"id":"T11","span":{"begin":266,"end":274},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"mat_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MAT_0000303"},{"id":"A11","pred":"mat_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MAT_0000034"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"sentences","denotations":[{"id":"T16","span":{"begin":0,"end":327},"obj":"Sentence"},{"id":"T16","span":{"begin":0,"end":327},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T16","span":{"begin":0,"end":327},"obj":"Sentence"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T20","span":{"begin":78,"end":97},"obj":"Body_part"},{"id":"T21","span":{"begin":99,"end":119},"obj":"Body_part"},{"id":"T22","span":{"begin":266,"end":279},"obj":"Body_part"},{"id":"T23","span":{"begin":296,"end":306},"obj":"Body_part"}],"attributes":[{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL_0000192"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/GO_0031012"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0000415"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CL_0000235"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}

{"project":"CL-cell","denotations":[{"id":"T24","span":{"begin":78,"end":97},"obj":"Cell"},{"id":"T25","span":{"begin":296,"end":306},"obj":"Cell"},{"id":"T27","span":{"begin":307,"end":316},"obj":"Cell"}],"attributes":[{"id":"A24","pred":"cl_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CL:0000192"},{"id":"A25","pred":"cl_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CL:0000235"},{"id":"A26","pred":"cl_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CL:0000394"},{"id":"A27","pred":"cl_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CL:0000891"}],"text":"Thus, the interaction of LDL and Lp(a) with four atheroma components, namely, smooth muscle cells, extracellular matrix, LpL, and SMase, represents a physiologically plausible mechanism for massive, focal retention and aggregation of atherogenic lipoproteins in the arterial wall with subsequent macrophage foam cell formation."}