| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-80 |
Sentence |
denotes |
Role of the plasma membrane in cholesterol esterification in rat hepatoma cells. |
| T2 |
81-180 |
Sentence |
denotes |
The source of the cholesterol used for ester synthesis by cultured rat hepatoma cells was examined. |
| T3 |
181-340 |
Sentence |
denotes |
The activities synthesizing and esterifying cholesterol co-distributed with RNA at a high buoyant density, presumably in the rough endoplasmic reticulum (RER). |
| T4 |
341-522 |
Sentence |
denotes |
Cholesterol mass was undetectable in the RER, and the transfer of cholesterol synthesized in the RER to the cell surface was more than 100 times greater than was its esterification. |
| T5 |
523-654 |
Sentence |
denotes |
Similarly, essentially all of the cholesterol liberated from ingested intracellular lipoproteins was recovered at the cell surface. |
| T6 |
655-829 |
Sentence |
denotes |
The plasma membranes, which contained approximately 87% of cell cholesterol, provided > 100 times more cholesterol for esterification in the RER than did nascent cholesterol. |
| T7 |
830-913 |
Sentence |
denotes |
The supply of cholesterol was rate-limiting for esterification in cell homogenates. |
| T8 |
914-1063 |
Sentence |
denotes |
Prior oxidation of plasma membrane cholesterol in intact cells reduced the acyl-CoA:cholesterol acyltransferase activity in isolates proportionately. |
| T9 |
1064-1251 |
Sentence |
denotes |
Finally, cholesterol in hepatoma plasma membranes was a far better substrate for in vitro esterification than was that in fibroblast plasma membranes, red blood cell ghosts, or liposomes. |
| T10 |
1252-1510 |
Sentence |
denotes |
We conclude that the level of saturation of acyl-CoA:cholesterol acyltransferase, controlled principally through the bidirectional movement of the substrate between plasma membranes and RER, plays a major role in the regulation of cholesterol esterification. |
| T1 |
0-80 |
Sentence |
denotes |
Role of the plasma membrane in cholesterol esterification in rat hepatoma cells. |
| T2 |
81-180 |
Sentence |
denotes |
The source of the cholesterol used for ester synthesis by cultured rat hepatoma cells was examined. |
| T3 |
181-340 |
Sentence |
denotes |
The activities synthesizing and esterifying cholesterol co-distributed with RNA at a high buoyant density, presumably in the rough endoplasmic reticulum (RER). |
| T4 |
341-522 |
Sentence |
denotes |
Cholesterol mass was undetectable in the RER, and the transfer of cholesterol synthesized in the RER to the cell surface was more than 100 times greater than was its esterification. |
| T5 |
523-654 |
Sentence |
denotes |
Similarly, essentially all of the cholesterol liberated from ingested intracellular lipoproteins was recovered at the cell surface. |
| T6 |
655-829 |
Sentence |
denotes |
The plasma membranes, which contained approximately 87% of cell cholesterol, provided > 100 times more cholesterol for esterification in the RER than did nascent cholesterol. |
| T7 |
830-913 |
Sentence |
denotes |
The supply of cholesterol was rate-limiting for esterification in cell homogenates. |
| T8 |
914-1063 |
Sentence |
denotes |
Prior oxidation of plasma membrane cholesterol in intact cells reduced the acyl-CoA:cholesterol acyltransferase activity in isolates proportionately. |
| T9 |
1064-1251 |
Sentence |
denotes |
Finally, cholesterol in hepatoma plasma membranes was a far better substrate for in vitro esterification than was that in fibroblast plasma membranes, red blood cell ghosts, or liposomes. |
| T10 |
1252-1510 |
Sentence |
denotes |
We conclude that the level of saturation of acyl-CoA:cholesterol acyltransferase, controlled principally through the bidirectional movement of the substrate between plasma membranes and RER, plays a major role in the regulation of cholesterol esterification. |
