PubMed:8307982
Annnotations
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-138 | Sentence | denotes | G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. |
| T2 | 139-220 | Sentence | denotes | A study of the molecular mechanisms involved in inflammatory cytokine expression. |
| T3 | 221-361 | Sentence | denotes | It is believed that induction of cytokine expression by bacterial cell wall components plays a role in the development and course of sepsis. |
| T4 | 362-431 | Sentence | denotes | However, most attention has been focused on lipopolysaccharide (LPS). |
| T5 | 432-752 | Sentence | denotes | We studied the ability of N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra), a naturally occurring breakdown product of peptidoglycan that is produced by soluble lytic transglycosylase of Escherichia coli, to induce cytokine expression in human monocytes. |
| T6 | 753-920 | Sentence | denotes | G(Anh)MTetra was found to strongly induce interleukin (IL)-1 beta and IL-6 mRNA expression after 2 h and IL-1 beta and IL-6 protein secretion after 48 h of activation. |
| T7 | 921-1169 | Sentence | denotes | The increase in mRNA accumulation was at least partly due to an increase in the transcription rates of the respective genes and was accompanied by a strong induction of nuclear factor-kappa B and activator protein-1 transcription factor expression. |
| T8 | 1170-1396 | Sentence | denotes | Experiments using inhibitors of protein kinase C, protein kinase A, and tyrosine kinase-dependent pathways revealed that G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression involves activation of an H7-inhibitable pathway. |
| T9 | 1397-1620 | Sentence | denotes | By using the protein synthesis inhibitor cycloheximide, it was shown that G(Anh)MTetra-induced IL-6 mRNA expression depends on the synthesis of new protein, whereas G(Anh)MTetra-induced IL-1 beta mRNA accumulation does not. |
| T10 | 1621-1854 | Sentence | denotes | When responses to G(Anh)MTetra were compared with those to LPS and muramyldipeptide (MDP), it was found that the optimal response to G(Anh)MTetra induction was similar to that of LPS but significantly higher than the response to MDP. |
| T11 | 1855-2064 | Sentence | denotes | Furthermore, maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression could be enhanced by co-stimulation with LPS or MDP, suggesting that different receptors and/or transduction pathways were involved. |
| T12 | 2065-2249 | Sentence | denotes | These results indicate that G(Anh)MTetra induces IL-1 beta and IL-6 expression in human monocytes suggesting a possible role for G(Anh)MTetra in the release of cytokines during sepsis. |
| T1 | 0-138 | Sentence | denotes | G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. |
| T2 | 139-220 | Sentence | denotes | A study of the molecular mechanisms involved in inflammatory cytokine expression. |
| T3 | 221-361 | Sentence | denotes | It is believed that induction of cytokine expression by bacterial cell wall components plays a role in the development and course of sepsis. |
| T4 | 362-431 | Sentence | denotes | However, most attention has been focused on lipopolysaccharide (LPS). |
| T5 | 432-752 | Sentence | denotes | We studied the ability of N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra), a naturally occurring breakdown product of peptidoglycan that is produced by soluble lytic transglycosylase of Escherichia coli, to induce cytokine expression in human monocytes. |
| T6 | 753-920 | Sentence | denotes | G(Anh)MTetra was found to strongly induce interleukin (IL)-1 beta and IL-6 mRNA expression after 2 h and IL-1 beta and IL-6 protein secretion after 48 h of activation. |
| T7 | 921-1169 | Sentence | denotes | The increase in mRNA accumulation was at least partly due to an increase in the transcription rates of the respective genes and was accompanied by a strong induction of nuclear factor-kappa B and activator protein-1 transcription factor expression. |
| T8 | 1170-1396 | Sentence | denotes | Experiments using inhibitors of protein kinase C, protein kinase A, and tyrosine kinase-dependent pathways revealed that G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression involves activation of an H7-inhibitable pathway. |
| T9 | 1397-1620 | Sentence | denotes | By using the protein synthesis inhibitor cycloheximide, it was shown that G(Anh)MTetra-induced IL-6 mRNA expression depends on the synthesis of new protein, whereas G(Anh)MTetra-induced IL-1 beta mRNA accumulation does not. |
| T10 | 1621-1854 | Sentence | denotes | When responses to G(Anh)MTetra were compared with those to LPS and muramyldipeptide (MDP), it was found that the optimal response to G(Anh)MTetra induction was similar to that of LPS but significantly higher than the response to MDP. |
| T11 | 1855-2064 | Sentence | denotes | Furthermore, maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression could be enhanced by co-stimulation with LPS or MDP, suggesting that different receptors and/or transduction pathways were involved. |
| T12 | 2065-2249 | Sentence | denotes | These results indicate that G(Anh)MTetra induces IL-1 beta and IL-6 expression in human monocytes suggesting a possible role for G(Anh)MTetra in the release of cytokines during sepsis. |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 617-630 | Glycan_Motif | denotes | peptidoglycan | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00023MO |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 617-630 | https://glytoucan.org/Structures/Glycans/G00023MO | denotes | peptidoglycan |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-138 | Sentence | denotes | G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. |
| T2 | 139-220 | Sentence | denotes | A study of the molecular mechanisms involved in inflammatory cytokine expression. |
| T3 | 221-361 | Sentence | denotes | It is believed that induction of cytokine expression by bacterial cell wall components plays a role in the development and course of sepsis. |
| T4 | 362-431 | Sentence | denotes | However, most attention has been focused on lipopolysaccharide (LPS). |
| T5 | 432-752 | Sentence | denotes | We studied the ability of N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra), a naturally occurring breakdown product of peptidoglycan that is produced by soluble lytic transglycosylase of Escherichia coli, to induce cytokine expression in human monocytes. |
| T6 | 753-920 | Sentence | denotes | G(Anh)MTetra was found to strongly induce interleukin (IL)-1 beta and IL-6 mRNA expression after 2 h and IL-1 beta and IL-6 protein secretion after 48 h of activation. |
| T7 | 921-1169 | Sentence | denotes | The increase in mRNA accumulation was at least partly due to an increase in the transcription rates of the respective genes and was accompanied by a strong induction of nuclear factor-kappa B and activator protein-1 transcription factor expression. |
| T8 | 1170-1396 | Sentence | denotes | Experiments using inhibitors of protein kinase C, protein kinase A, and tyrosine kinase-dependent pathways revealed that G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression involves activation of an H7-inhibitable pathway. |
| T9 | 1397-1620 | Sentence | denotes | By using the protein synthesis inhibitor cycloheximide, it was shown that G(Anh)MTetra-induced IL-6 mRNA expression depends on the synthesis of new protein, whereas G(Anh)MTetra-induced IL-1 beta mRNA accumulation does not. |
| T10 | 1621-1854 | Sentence | denotes | When responses to G(Anh)MTetra were compared with those to LPS and muramyldipeptide (MDP), it was found that the optimal response to G(Anh)MTetra induction was similar to that of LPS but significantly higher than the response to MDP. |
| T11 | 1855-2064 | Sentence | denotes | Furthermore, maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression could be enhanced by co-stimulation with LPS or MDP, suggesting that different receptors and/or transduction pathways were involved. |
| T12 | 2065-2249 | Sentence | denotes | These results indicate that G(Anh)MTetra induces IL-1 beta and IL-6 expression in human monocytes suggesting a possible role for G(Anh)MTetra in the release of cytokines during sepsis. |
| T1 | 0-138 | Sentence | denotes | G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. |
| T2 | 139-220 | Sentence | denotes | A study of the molecular mechanisms involved in inflammatory cytokine expression. |
| T3 | 221-361 | Sentence | denotes | It is believed that induction of cytokine expression by bacterial cell wall components plays a role in the development and course of sepsis. |
| T4 | 362-431 | Sentence | denotes | However, most attention has been focused on lipopolysaccharide (LPS). |
| T5 | 432-752 | Sentence | denotes | We studied the ability of N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra), a naturally occurring breakdown product of peptidoglycan that is produced by soluble lytic transglycosylase of Escherichia coli, to induce cytokine expression in human monocytes. |
| T6 | 753-920 | Sentence | denotes | G(Anh)MTetra was found to strongly induce interleukin (IL)-1 beta and IL-6 mRNA expression after 2 h and IL-1 beta and IL-6 protein secretion after 48 h of activation. |
| T7 | 921-1169 | Sentence | denotes | The increase in mRNA accumulation was at least partly due to an increase in the transcription rates of the respective genes and was accompanied by a strong induction of nuclear factor-kappa B and activator protein-1 transcription factor expression. |
| T8 | 1170-1396 | Sentence | denotes | Experiments using inhibitors of protein kinase C, protein kinase A, and tyrosine kinase-dependent pathways revealed that G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression involves activation of an H7-inhibitable pathway. |
| T9 | 1397-1620 | Sentence | denotes | By using the protein synthesis inhibitor cycloheximide, it was shown that G(Anh)MTetra-induced IL-6 mRNA expression depends on the synthesis of new protein, whereas G(Anh)MTetra-induced IL-1 beta mRNA accumulation does not. |
| T10 | 1621-1854 | Sentence | denotes | When responses to G(Anh)MTetra were compared with those to LPS and muramyldipeptide (MDP), it was found that the optimal response to G(Anh)MTetra induction was similar to that of LPS but significantly higher than the response to MDP. |
| T11 | 1855-2064 | Sentence | denotes | Furthermore, maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression could be enhanced by co-stimulation with LPS or MDP, suggesting that different receptors and/or transduction pathways were involved. |
| T12 | 2065-2249 | Sentence | denotes | These results indicate that G(Anh)MTetra induces IL-1 beta and IL-6 expression in human monocytes suggesting a possible role for G(Anh)MTetra in the release of cytokines during sepsis. |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 2114-2123 | gene:3553 | denotes | IL-1 beta |
| T1 | 2242-2248 | disease:C0036690 | denotes | sepsis |
| T2 | 2114-2123 | gene:3553 | denotes | IL-1 beta |
| T3 | 2242-2248 | disease:C0243026 | denotes | sepsis |
| T4 | 2128-2132 | gene:3569 | denotes | IL-6 |
| T5 | 2242-2248 | disease:C0036690 | denotes | sepsis |
| T6 | 2128-2132 | gene:3569 | denotes | IL-6 |
| T7 | 2242-2248 | disease:C0243026 | denotes | sepsis |
| R1 | T0 | T1 | associated_with | IL-1 beta,sepsis |
| R2 | T2 | T3 | associated_with | IL-1 beta,sepsis |
| R3 | T4 | T5 | associated_with | IL-6,sepsis |
| R4 | T6 | T7 | associated_with | IL-6,sepsis |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 71-89 | protein | denotes | interleukin-1 beta |
| T2 | 94-107 | protein | denotes | interleukin-6 |
| T3 | 122-137 | cell_type | denotes | human monocytes |
| T4 | 187-208 | protein | denotes | inflammatory cytokine |
| T5 | 254-262 | protein | denotes | cytokine |
| T6 | 659-681 | protein | denotes | lytic transglycosylase |
| T7 | 713-721 | protein | denotes | cytokine |
| T8 | 736-751 | cell_type | denotes | human monocytes |
| T9 | 795-818 | protein | denotes | interleukin (IL)-1 beta |
| T10 | 823-832 | RNA | denotes | IL-6 mRNA |
| T11 | 858-867 | protein | denotes | IL-1 beta |
| T12 | 872-884 | protein | denotes | IL-6 protein |
| T13 | 1039-1044 | DNA | denotes | genes |
| T14 | 1202-1218 | protein | denotes | protein kinase C |
| T15 | 1220-1236 | protein | denotes | protein kinase A |
| T16 | 1312-1321 | protein | denotes | IL-1 beta |
| T17 | 1326-1335 | RNA | denotes | IL-6 mRNA |
| T18 | 1492-1501 | RNA | denotes | IL-6 mRNA |
| T19 | 1583-1592 | protein | denotes | IL-1 beta |
| T20 | 1897-1906 | protein | denotes | IL-1 beta |
| T21 | 1911-1920 | RNA | denotes | IL-6 mRNA |
| T22 | 2114-2123 | protein | denotes | IL-1 beta |
| T23 | 2128-2132 | protein | denotes | IL-6 |
| T24 | 2147-2162 | cell_type | denotes | human monocytes |
| T25 | 2225-2234 | protein | denotes | cytokines |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-138 | Sentence | denotes | G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. |
| S2 | 139-220 | Sentence | denotes | A study of the molecular mechanisms involved in inflammatory cytokine expression. |
| S3 | 221-361 | Sentence | denotes | It is believed that induction of cytokine expression by bacterial cell wall components plays a role in the development and course of sepsis. |
| S4 | 362-431 | Sentence | denotes | However, most attention has been focused on lipopolysaccharide (LPS). |
| S5 | 432-752 | Sentence | denotes | We studied the ability of N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra), a naturally occurring breakdown product of peptidoglycan that is produced by soluble lytic transglycosylase of Escherichia coli, to induce cytokine expression in human monocytes. |
| S6 | 753-920 | Sentence | denotes | G(Anh)MTetra was found to strongly induce interleukin (IL)-1 beta and IL-6 mRNA expression after 2 h and IL-1 beta and IL-6 protein secretion after 48 h of activation. |
| S7 | 921-1169 | Sentence | denotes | The increase in mRNA accumulation was at least partly due to an increase in the transcription rates of the respective genes and was accompanied by a strong induction of nuclear factor-kappa B and activator protein-1 transcription factor expression. |
| S8 | 1170-1396 | Sentence | denotes | Experiments using inhibitors of protein kinase C, protein kinase A, and tyrosine kinase-dependent pathways revealed that G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression involves activation of an H7-inhibitable pathway. |
| S9 | 1397-1620 | Sentence | denotes | By using the protein synthesis inhibitor cycloheximide, it was shown that G(Anh)MTetra-induced IL-6 mRNA expression depends on the synthesis of new protein, whereas G(Anh)MTetra-induced IL-1 beta mRNA accumulation does not. |
| S10 | 1621-1854 | Sentence | denotes | When responses to G(Anh)MTetra were compared with those to LPS and muramyldipeptide (MDP), it was found that the optimal response to G(Anh)MTetra induction was similar to that of LPS but significantly higher than the response to MDP. |
| S11 | 1855-2064 | Sentence | denotes | Furthermore, maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression could be enhanced by co-stimulation with LPS or MDP, suggesting that different receptors and/or transduction pathways were involved. |
| S12 | 2065-2249 | Sentence | denotes | These results indicate that G(Anh)MTetra induces IL-1 beta and IL-6 expression in human monocytes suggesting a possible role for G(Anh)MTetra in the release of cytokines during sepsis. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-12 | NP | denotes | G(Anh)MTetra |
| C2 | 14-61 | NP | denotes | a natural bacterial cell wall breakdown product |
| C4 | 71-89 | NP | denotes | interleukin-1 beta |
| C3 | 71-137 | NP | denotes | interleukin-1 beta and interleukin-6 expression in human monocytes |
| C5 | 254-273 | NP | denotes | cytokine expression |
| C6 | 354-360 | NP | denotes | sepsis |
| C7 | 406-430 | NP | denotes | lipopolysaccharide (LPS) |
| C8 | 458-572 | NP | denotes | N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra) |
| C9 | 574-630 | NP | denotes | a naturally occurring breakdown product of peptidoglycan |
| C10 | 631-635 | NP | denotes | that |
| C11 | 713-751 | NP | denotes | cytokine expression in human monocytes |
| C12 | 753-765 | NP | denotes | G(Anh)MTetra |
| C13 | 795-818 | NP | denotes | interleukin (IL)-1 beta |
| C14 | 858-867 | NP | denotes | IL-1 beta |
| C16 | 1291-1304 | NP | denotes | G(Anh)MTetra- |
| C15 | 1291-1346 | NP | denotes | G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression |
| C18 | 1471-1484 | NP | denotes | G(Anh)MTetra- |
| C17 | 1471-1512 | NP | denotes | G(Anh)MTetra-induced IL-6 mRNA expression |
| C19 | 1562-1575 | NP | denotes | G(Anh)MTetra- |
| C20 | 1626-1635 | NP | denotes | responses |
| C21 | 1639-1651 | NP | denotes | G(Anh)MTetra |
| C22 | 1671-1676 | NP | denotes | those |
| C23 | 1680-1683 | NP | denotes | LPS |
| C24 | 1688-1710 | NP | denotes | muramyldipeptide (MDP) |
| C25 | 1730-1750 | NP | denotes | the optimal response |
| C26 | 1792-1796 | NP | denotes | that |
| C27 | 1800-1803 | NP | denotes | LPS |
| C28 | 1850-1853 | NP | denotes | MDP |
| C30 | 1876-1889 | NP | denotes | G(Anh)MTetra- |
| C29 | 1868-1931 | NP | denotes | maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression |
| C31 | 1973-1976 | NP | denotes | LPS |
| C32 | 1980-1983 | NP | denotes | MDP |
| C33 | 2093-2105 | NP | denotes | G(Anh)MTetra |
| C35 | 2114-2123 | NP | denotes | IL-1 beta |
| C34 | 2114-2162 | NP | denotes | IL-1 beta and IL-6 expression in human monocytes |
| C36 | 2194-2206 | NP | denotes | G(Anh)MTetra |
| C37 | 2242-2248 | NP | denotes | sepsis |
| R1 | C2 | C1 | coref-appos | a natural bacterial cell wall breakdown product,G(Anh)MTetra |
| R2 | C8 | C1 | coref-ident | "N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra)",G(Anh)MTetra |
| R3 | C9 | C8 | coref-appos | a naturally occurring breakdown product of peptidoglycan,"N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra)" |
| R4 | C10 | C9 | coref-relat | that,a naturally occurring breakdown product of peptidoglycan |
| R5 | C11 | C5 | coref-ident | cytokine expression in human monocytes,cytokine expression |
| R6 | C12 | C8 | coref-ident | G(Anh)MTetra,"N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine (G(Anh)MTetra)" |
| R7 | C13 | C4 | coref-ident | interleukin (IL)-1 beta,interleukin-1 beta |
| R8 | C14 | C13 | coref-ident | IL-1 beta,interleukin (IL)-1 beta |
| R9 | C15 | C12 | coref-ident | G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression,G(Anh)MTetra |
| R10 | C18 | C16 | coref-part-whole | G(Anh)MTetra-,G(Anh)MTetra- |
| R11 | C17 | C15 | coref-ident | G(Anh)MTetra-induced IL-6 mRNA expression,G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression |
| R12 | C19 | C17 | coref-ident | G(Anh)MTetra-,G(Anh)MTetra-induced IL-6 mRNA expression |
| R13 | C21 | C19 | coref-ident | G(Anh)MTetra,G(Anh)MTetra- |
| R14 | C22 | C20 | coref-pron | those,responses |
| R15 | C23 | C7 | coref-ident | LPS,lipopolysaccharide (LPS) |
| R16 | C26 | C25 | coref-pron | that,the optimal response |
| R17 | C27 | C23 | coref-ident | LPS,LPS |
| R18 | C28 | C24 | coref-ident | MDP,muramyldipeptide (MDP) |
| R19 | C30 | C21 | coref-ident | G(Anh)MTetra-,G(Anh)MTetra |
| R20 | C29 | C16 | coref-other | maximal G(Anh)MTetra-induced IL-1 beta and IL-6 mRNA expression,G(Anh)MTetra- |
| R21 | C31 | C27 | coref-ident | LPS,LPS |
| R22 | C32 | C28 | coref-ident | MDP,MDP |
| R23 | C33 | C21 | coref-ident | G(Anh)MTetra,G(Anh)MTetra |
| R24 | C35 | C3 | coref-ident | IL-1 beta,interleukin-1 beta and interleukin-6 expression in human monocytes |
| R25 | C34 | C13 | coref-ident | IL-1 beta and IL-6 expression in human monocytes,interleukin (IL)-1 beta |
| R26 | C36 | C33 | coref-ident | G(Anh)MTetra,G(Anh)MTetra |
| R27 | C37 | C6 | coref-ident | sepsis,sepsis |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-12 | other_organic_compound | denotes | G(Anh)MTetra |
| T2 | 24-61 | other_organic_compound | denotes | bacterial cell wall breakdown product |
| T3 | 71-89 | protein_molecule | denotes | interleukin-1 beta |
| T4 | 94-107 | protein_molecule | denotes | interleukin-6 |
| T5 | 122-137 | cell_type | denotes | human monocytes |
| T6 | 154-174 | other_name | denotes | molecular mechanisms |
| T7 | 187-208 | protein_family_or_group | denotes | inflammatory cytokine |
| T8 | 254-262 | protein_family_or_group | denotes | cytokine |
| T9 | 277-307 | other_name | denotes | bacterial cell wall components |
| T10 | 406-424 | lipid | denotes | lipopolysaccharide |
| T11 | 426-429 | lipid | denotes | LPS |
| T12 | 458-557 | other_organic_compound | denotes | N-acetylglucosaminyl-1,6-anhydro-N-acetylmuramyl-L-alanyl-D- isoglutamyl-m-diaminopimelyl-D-alanine |
| T13 | 559-571 | other_organic_compound | denotes | G(Anh)MTetra |
| T14 | 617-630 | carbohydrate | denotes | peptidoglycan |
| T15 | 659-681 | protein_molecule | denotes | lytic transglycosylase |
| T16 | 685-701 | mono_cell | denotes | Escherichia coli |
| T17 | 713-721 | protein_family_or_group | denotes | cytokine |
| T18 | 736-751 | cell_type | denotes | human monocytes |
| T19 | 753-765 | other_organic_compound | denotes | G(Anh)MTetra |
| T20 | 795-818 | protein_molecule | denotes | interleukin (IL)-1 beta |
| T21 | 823-827 | protein_molecule | denotes | IL-6 |
| T22 | 858-867 | protein_molecule | denotes | IL-1 beta |
| T23 | 872-884 | protein_molecule | denotes | IL-6 protein |
| T24 | 937-954 | other_name | denotes | mRNA accumulation |
| T25 | 1001-1020 | other_name | denotes | transcription rates |
| T26 | 1039-1044 | DNA_family_or_group | denotes | genes |
| T27 | 1202-1218 | protein_molecule | denotes | protein kinase C |
| T28 | 1220-1236 | protein_molecule | denotes | protein kinase A |
| T29 | 1242-1276 | other_name | denotes | tyrosine kinase-dependent pathways |
| T30 | 1291-1303 | other_organic_compound | denotes | G(Anh)MTetra |
| T31 | 1312-1321 | protein_molecule | denotes | IL-1 beta |
| T32 | 1326-1330 | protein_molecule | denotes | IL-6 |
| T33 | 1373-1395 | other_name | denotes | H7-inhibitable pathway |
| T34 | 1438-1451 | other_organic_compound | denotes | cycloheximide |
| T35 | 1471-1483 | other_organic_compound | denotes | G(Anh)MTetra |
| T36 | 1492-1496 | protein_molecule | denotes | IL-6 |
| T37 | 1562-1574 | other_organic_compound | denotes | G(Anh)MTetra |
| T38 | 1583-1592 | protein_molecule | denotes | IL-1 beta |
| T39 | 1593-1610 | other_name | denotes | mRNA accumulation |
| T40 | 1639-1651 | other_organic_compound | denotes | G(Anh)MTetra |
| T41 | 1680-1683 | lipid | denotes | LPS |
| T42 | 1688-1704 | amino_acid_monomer | denotes | muramyldipeptide |
| T43 | 1706-1709 | amino_acid_monomer | denotes | MDP |
| T44 | 1754-1766 | other_organic_compound | denotes | G(Anh)MTetra |
| T45 | 1800-1803 | lipid | denotes | LPS |
| T46 | 1850-1853 | amino_acid_monomer | denotes | MDP |
| T47 | 1876-1888 | other_organic_compound | denotes | G(Anh)MTetra |
| T48 | 1897-1906 | protein_molecule | denotes | IL-1 beta |
| T49 | 1911-1915 | protein_molecule | denotes | IL-6 |
| T50 | 1973-1976 | lipid | denotes | LPS |
| T51 | 1980-1983 | amino_acid_monomer | denotes | MDP |
| T52 | 2028-2049 | other_name | denotes | transduction pathways |
| T53 | 2093-2105 | other_organic_compound | denotes | G(Anh)MTetra |
| T54 | 2114-2123 | protein_molecule | denotes | IL-1 beta |
| T55 | 2128-2132 | protein_molecule | denotes | IL-6 |
| T56 | 2147-2162 | cell_type | denotes | human monocytes |
| T57 | 2194-2206 | other_organic_compound | denotes | G(Anh)MTetra |
| T58 | 2225-2234 | protein_family_or_group | denotes | cytokines |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 354-360 | Phenotype | denotes | sepsis | HP:0100806 |
| T2 | 2242-2248 | Phenotype | denotes | sepsis | HP:0100806 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 122-127 | OrganismTaxon | denotes | human | 9606 |
| T2 | 354-360 | OrganismTaxon | denotes | sepsis | 137507 |
| T3 | 685-701 | OrganismTaxon | denotes | Escherichia coli | 562 |
| T4 | 736-741 | OrganismTaxon | denotes | human | 9606 |
| T5 | 2147-2152 | OrganismTaxon | denotes | human | 9606 |
| T6 | 2242-2248 | OrganismTaxon | denotes | sepsis | 137507 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 39-43 | Body_part | denotes | wall | http://purl.obolibrary.org/obo/UBERON_0000060 |
| T2 | 128-137 | Body_part | denotes | monocytes | http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054 |
| T4 | 292-296 | Body_part | denotes | wall | http://purl.obolibrary.org/obo/UBERON_0000060 |
| T5 | 742-751 | Body_part | denotes | monocytes | http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054 |
| T7 | 2153-2162 | Body_part | denotes | monocytes | http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 128-137 | Cell | denotes | monocytes | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T3 | 742-751 | Cell | denotes | monocytes | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T5 | 2153-2162 | Cell | denotes | monocytes | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |