Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-57 |
Sentence |
denotes |
Ascorbic acid and insulin secretion in pancreatic islets. |
T2 |
58-235 |
Sentence |
denotes |
The effect of ascorbic acid on glucose-induced insulin release from single pancreatic islets was measured using a new, ultra-sensitive enzyme-linked immunosorbent insulin assay. |
T3 |
236-347 |
Sentence |
denotes |
Within 20 s ascorbic acid inhibited insulin secretion; inhibition was dose dependent and completely reversible. |
T4 |
348-480 |
Sentence |
denotes |
There was a 50% inhibition of the secretory response with 200 microM ascorbic acid and 90% inhibition with 400 microM ascorbic acid. |
T5 |
481-656 |
Sentence |
denotes |
The decrease in insulin secretion was recorded as a reduction of the amplitudes of the fast insulin transients, which give rise to the oscillatory nature of insulin secretion. |
T6 |
657-790 |
Sentence |
denotes |
The inhibition of glucose-induced insulin release by ascorbic acid was associated with hyperpolarization of the pancreatic beta-cell. |
T7 |
791-920 |
Sentence |
denotes |
Suppression of glucose-induced membrane depolarization was evident after 20 s, was dose dependent, and was completely reversible. |
T8 |
921-1031 |
Sentence |
denotes |
The data here may provide the first explanation of why plasma ascorbate concentrations are tightly controlled. |
T1 |
0-57 |
Sentence |
denotes |
Ascorbic acid and insulin secretion in pancreatic islets. |
T2 |
58-235 |
Sentence |
denotes |
The effect of ascorbic acid on glucose-induced insulin release from single pancreatic islets was measured using a new, ultra-sensitive enzyme-linked immunosorbent insulin assay. |
T3 |
236-347 |
Sentence |
denotes |
Within 20 s ascorbic acid inhibited insulin secretion; inhibition was dose dependent and completely reversible. |
T4 |
348-480 |
Sentence |
denotes |
There was a 50% inhibition of the secretory response with 200 microM ascorbic acid and 90% inhibition with 400 microM ascorbic acid. |
T5 |
481-656 |
Sentence |
denotes |
The decrease in insulin secretion was recorded as a reduction of the amplitudes of the fast insulin transients, which give rise to the oscillatory nature of insulin secretion. |
T6 |
657-790 |
Sentence |
denotes |
The inhibition of glucose-induced insulin release by ascorbic acid was associated with hyperpolarization of the pancreatic beta-cell. |
T7 |
791-920 |
Sentence |
denotes |
Suppression of glucose-induced membrane depolarization was evident after 20 s, was dose dependent, and was completely reversible. |
T8 |
921-1031 |
Sentence |
denotes |
The data here may provide the first explanation of why plasma ascorbate concentrations are tightly controlled. |