> top > docs > PubMed:8255162 > annotations

PubMed:8255162 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 80-100 protein denotes Blood cell receptors
T2 161-182 protein denotes monoclonal antibodies
T3 184-188 protein denotes mAbs
T4 234-251 protein denotes surface receptors
T5 255-280 cell_type denotes lymphocyte subpopulations
T6 640-657 protein denotes surface receptors
T7 781-812 cell_type denotes helper-inducer (memory) T cells
T8 814-846 cell_type denotes CD4+CD45R0+CD45RA-CD29highCD11a+
T9 849-862 cell_type denotes CD20+ B cells
T10 868-885 cell_type denotes cytotoxic T cells
T11 887-902 cell_type denotes CD8+CD56+/CD57+
T12 944-948 protein denotes mAbs
T13 1334-1351 protein denotes surface receptors
T14 1355-1372 cell_type denotes white blood cells
T15 2041-2058 cell_type denotes CD4+CD45R0+ cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-76 Sentence denotes Chlorinated dibenzo-p-dioxins and dibenzofurans and the human immune system.
S2 77-154 Sentence denotes 1. Blood cell receptors in volunteers with moderately increased body burdens.
S3 155-517 Sentence denotes Using monoclonal antibodies (mAbs) and flow cytometry, we studied a variety of surface receptors on lymphocyte subpopulations of workers with moderately increased body burdens of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of other polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF), expressed here as International-Toxicity Equivalencies (I-TE).
S4 518-769 Sentence denotes The hypothesis to be tested was whether or not humans exhibit a similar susceptibility to PCDDs/PCDFs with respect to the surface receptors found previously to respond to small doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Callithrix jacchus.
S5 770-904 Sentence denotes These are: helper-inducer (memory) T cells (CD4+CD45R0+CD45RA-CD29highCD11a+), CD20+ B cells, and cytotoxic T cells (CD8+CD56+/CD57+).
S6 905-1035 Sentence denotes Furthermore, 68 triple-labellings with mAbs were performed on the cells of each volunteer to possibly generate further hypotheses.
S7 1036-1150 Sentence denotes It was evaluated whether any of the variables might be used as a biomarker of effects for this class of compounds.
S8 1151-1796 Sentence denotes There were two main goals: (1) to evaluate whether workers with a moderately increased PCDD/PCDF-body burden [25-140 ppt TCDD or 104-522 ppt I-TE in blood fat] exhibit changes in the surface receptors of white blood cells, as observed in previous studies in non-human primates, and (2) to clarify whether persons at the upper range [10-23 ppt TCDD or 30-90 ppt I-TE in blood fat] of the body burden reference values of a not particularly exposed population show detectable deviations in these immunological variables, when compared with persons at the lower and medium range [1-3 ppt TCDD or 9-29 ppt I-TE] of these body burden reference values.
S9 1797-1894 Sentence denotes Regression analysis of our data revealed slight trends for some of the biomarkers (e.g. CD45R0+).
S10 1895-1940 Sentence denotes With one exception, these were all increases.
S11 1941-1999 Sentence denotes None of the alterations observed are of medical relevance.
S12 2000-2150 Sentence denotes The slight increase in the percentage of CD4+CD45R0+ cells remained significant even after covariant analysis taking age-related changes into account.
S13 2151-2360 Sentence denotes Altogether, the data do not provide any evidence to support an assumption that moderately increased body burdens of PCDDs/PCDFs in adults induce decreases in the cellular components of the human immune system.
S14 2361-2470 Sentence denotes Adult humans certainly are less susceptible to this action of PCDDs/PCDFs than adolescent Callithrix jacchus.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 52-75 NP denotes the human immune system
C2 104-153 NP denotes volunteers with moderately increased body burdens
C3 161-189 NP denotes monoclonal antibodies (mAbs)
C6 334-380 NP denotes 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and
C5 284-453 NP denotes workers with moderately increased body burdens of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of other polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF)
C4 221-516 NP denotes a variety of surface receptors on lymphocyte subpopulations of workers with moderately increased body burdens of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of other polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF), expressed here as International-Toxicity Equivalencies (I-TE)
C9 750-768 NP denotes Callithrix jacchus
C8 704-768 NP denotes 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Callithrix jacchus
C7 636-768 NP denotes the surface receptors found previously to respond to small doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Callithrix jacchus
C10 770-775 NP denotes These
C12 944-948 NP denotes mAbs
C11 918-948 NP denotes 68 triple-labellings with mAbs
C13 980-994 NP denotes each volunteer
C14 1068-1081 NP denotes the variables
C15 1126-1149 NP denotes this class of compounds
C16 1202-1310 NP denotes workers with a moderately increased PCDD/PCDF-body burden [25-140 ppt TCDD or 104-522 ppt I-TE in blood fat]
C17 1534-1566 NP denotes the body burden reference values
C18 1638-1667 NP denotes these immunological variables
C19 1761-1795 NP denotes these body burden reference values
C20 1820-1828 NP denotes our data
C21 1864-1878 NP denotes the biomarkers
C22 1915-1920 NP denotes these
C23 2163-2171 NP denotes the data
C24 2211-2224 NP denotes an assumption
C25 2225-2229 NP denotes that
C26 2336-2359 NP denotes the human immune system
C27 2440-2469 NP denotes adolescent Callithrix jacchus
R1 C5 C2 coref-other "workers with moderately increased body burdens of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of other polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF)",volunteers with moderately increased body burdens
R2 C8 C6 coref-ident "2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Callithrix jacchus","2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and"
R3 C7 C4 coref-other "the surface receptors found previously to respond to small doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Callithrix jacchus","a variety of surface receptors on lymphocyte subpopulations of workers with moderately increased body burdens of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of other polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF), expressed here as International-Toxicity Equivalencies (I-TE)"
R4 C10 C7 coref-pron These,"the surface receptors found previously to respond to small doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Callithrix jacchus"
R5 C12 C3 coref-ident mAbs,monoclonal antibodies (mAbs)
R6 C13 C2 coref-part-whole each volunteer,volunteers with moderately increased body burdens
R7 C14 C11 coref-ident the variables,68 triple-labellings with mAbs
R8 C15 C11 coref-ident this class of compounds,68 triple-labellings with mAbs
R9 C16 C5 coref-other workers with a moderately increased PCDD/PCDF-body burden [25-140 ppt TCDD or 104-522 ppt I-TE in blood fat],"workers with moderately increased body burdens of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of other polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF)"
R10 C18 C14 coref-ident these immunological variables,the variables
R11 C19 C17 coref-other these body burden reference values,the body burden reference values
R12 C22 C21 coref-pron these,the biomarkers
R13 C23 C20 coref-ident the data,our data
R14 C25 C24 coref-relat that,an assumption
R15 C26 C1 coref-ident the human immune system,the human immune system
R16 C27 C9 coref-part-whole adolescent Callithrix jacchus,Callithrix jacchus

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-29 other_organic_compound denotes Chlorinated dibenzo-p-dioxins
T2 34-47 other_organic_compound denotes dibenzofurans
T3 56-75 body_part denotes human immune system
T4 80-100 protein_family_or_group denotes Blood cell receptors
T5 104-114 multi_cell denotes volunteers
T6 161-182 protein_family_or_group denotes monoclonal antibodies
T7 184-188 protein_family_or_group denotes mAbs
T8 234-251 protein_family_or_group denotes surface receptors
T9 255-280 cell_type denotes lymphocyte subpopulations
T10 334-369 other_organic_compound denotes 2,3,7,8-tetrachlorodibenzo-p-dioxin
T11 371-375 other_organic_compound denotes TCDD
T12 390-423 other_organic_compound denotes polychlorinated dibenzo-p-dioxins
T13 428-441 other_organic_compound denotes dibenzofurans
T14 443-452 other_organic_compound denotes PCDD/PCDF
T15 473-509 other_name denotes International-Toxicity Equivalencies
T16 511-515 other_name denotes I-TE
T17 565-571 multi_cell denotes humans
T18 608-619 other_organic_compound denotes PCDDs/PCDFs
T19 640-657 protein_family_or_group denotes surface receptors
T20 704-739 other_organic_compound denotes 2,3,7,8-tetrachlorodibenzo-p-dioxin
T21 741-745 other_organic_compound denotes TCDD
T22 750-768 other_name denotes Callithrix jacchus
T23 781-804 cell_type denotes helper-inducer (memory)
T24 805-812 cell_type denotes T cells
T25 814-846 cell_type denotes CD4+CD45R0+CD45RA-CD29highCD11a+
T26 849-862 cell_type denotes CD20+ B cells
T27 868-885 cell_type denotes cytotoxic T cells
T28 887-902 cell_type denotes CD8+CD56+/CD57+
T29 944-948 protein_family_or_group denotes mAbs
T30 985-994 multi_cell denotes volunteer
T31 1202-1209 multi_cell denotes workers
T32 1238-1247 other_organic_compound denotes PCDD/PCDF
T33 1272-1276 other_organic_compound denotes TCDD
T34 1280-1296 other_name denotes 104-522 ppt I-TE
T35 1300-1309 lipid denotes blood fat
T36 1334-1351 protein_family_or_group denotes surface receptors
T37 1355-1372 cell_type denotes white blood cells
T38 1409-1427 multi_cell denotes non-human primates
T39 1494-1498 other_organic_compound denotes TCDD
T40 1502-1516 other_name denotes 30-90 ppt I-TE
T41 1520-1529 lipid denotes blood fat
T42 1538-1566 other_name denotes body burden reference values
T43 1644-1667 other_name denotes immunological variables
T44 1735-1739 other_organic_compound denotes TCDD
T45 1743-1756 other_name denotes 9-29 ppt I-TE
T46 1767-1795 other_name denotes body burden reference values
T47 1868-1878 other_name denotes biomarkers
T48 1885-1892 other_name denotes CD45R0+
T49 2041-2058 cell_type denotes CD4+CD45R0+ cells
T50 2251-2263 other_name denotes body burdens
T51 2267-2278 other_organic_compound denotes PCDDs/PCDFs
T52 2313-2332 cell_component denotes cellular components
T53 2340-2359 body_part denotes human immune system
T54 2361-2366 multi_cell denotes Adult
T55 2367-2373 multi_cell denotes humans
T56 2423-2434 other_organic_compound denotes PCDDs/PCDFs
T57 2440-2450 other_name denotes adolescent
T58 2451-2469 other_name denotes Callithrix jacchus