Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-131 |
Sentence |
denotes |
In vitro uptake of vitamin A from the retinol-binding plasma protein to mucosal epithelial cells from the monkey's small intestine. |
T2 |
132-403 |
Sentence |
denotes |
The in vitro uptake of retinol from its plasma carrier protein, the retinol-binding protein (RBP), to the cells of the monkey's small intestine has been studied. [3H]Retinol was readily delivered from the RBP to the cells without a concomitant cellular uptake of the RBP. |
T3 |
404-520 |
Sentence |
denotes |
The [3H]retinol accumulation in the cells was dependent on the temperature and was virtually abolished at 0 degrees. |
T4 |
521-586 |
Sentence |
denotes |
Several metabolic inhibitors could not impede the uptake process. |
T5 |
587-702 |
Sentence |
denotes |
The cellular [3H]retinol accumulation was linear for about 45 min and exhibited characteristic saturation kinetics. |
T6 |
703-853 |
Sentence |
denotes |
The uptake of [3H]retinol by the cells could be inhibited by RBP containing unlabeled retinol, vitamin A-depleted RBP, and Fab' fragments against RBP. |
T7 |
854-982 |
Sentence |
denotes |
In contrast, free, unlabeled retinol and the metabolite form of RBP, lacking retinol and affinity for prealbumin, were inactive. |
T8 |
983-1132 |
Sentence |
denotes |
It is therefore suggested that there is a receptor for vitamin A on the cell surface which recognizes the protein part of the protein-ligand complex. |
T1 |
0-131 |
Sentence |
denotes |
In vitro uptake of vitamin A from the retinol-binding plasma protein to mucosal epithelial cells from the monkey's small intestine. |
T2 |
132-403 |
Sentence |
denotes |
The in vitro uptake of retinol from its plasma carrier protein, the retinol-binding protein (RBP), to the cells of the monkey's small intestine has been studied. [3H]Retinol was readily delivered from the RBP to the cells without a concomitant cellular uptake of the RBP. |
T3 |
404-520 |
Sentence |
denotes |
The [3H]retinol accumulation in the cells was dependent on the temperature and was virtually abolished at 0 degrees. |
T4 |
521-586 |
Sentence |
denotes |
Several metabolic inhibitors could not impede the uptake process. |
T5 |
587-702 |
Sentence |
denotes |
The cellular [3H]retinol accumulation was linear for about 45 min and exhibited characteristic saturation kinetics. |
T6 |
703-853 |
Sentence |
denotes |
The uptake of [3H]retinol by the cells could be inhibited by RBP containing unlabeled retinol, vitamin A-depleted RBP, and Fab' fragments against RBP. |
T7 |
854-982 |
Sentence |
denotes |
In contrast, free, unlabeled retinol and the metabolite form of RBP, lacking retinol and affinity for prealbumin, were inactive. |
T8 |
983-1132 |
Sentence |
denotes |
It is therefore suggested that there is a receptor for vitamin A on the cell surface which recognizes the protein part of the protein-ligand complex. |