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sentences

Id Subject Object Predicate Lexical cue
T1 0-46 Sentence denotes 25-Hydroxyvitamin D transport in human plasma.
T2 47-117 Sentence denotes Isolation and partial characterization of calcifidiol-binding protein.
T3 118-250 Sentence denotes The binding protein for 25-hydroxycholecalciferol (25-OH-D3 or calcifidiol) in human plasma has been purified from Cohn Fraction IV.
T4 251-490 Sentence denotes Following in vitro labeling with 25-OH-[3H]D3, the isolation sequence of procedures included: DEAE-cellulose chromatography; gel filtration on Sephadex G-200; chromatography on DEAE-Sephadex; preparative polyacrylamide gel electrophoresis.
T5 491-672 Sentence denotes These procedures resulted in a calcifidiol-binding protein (Cal-BP) which had been purified approximately 170-fold, and which was homogeneous by physical and immunological criteria.
T6 673-811 Sentence denotes The purified Cal-BP had inter-alpha mobility, a sedimentation constant (S20, w) of 3.46 S, and a molecular weight of approximately 59,000.
T7 812-1037 Sentence denotes Sucrose gradient ultracentrifugation of Cal-BP and ligand incubations indicated that there was apparently one binding site for either cholecalciferol, calcifidiol or 1,25-dihydroxycholecalciferol per molecule of human Cal-BP.
T8 1038-1172 Sentence denotes The protein had highest affinity for calcifidiol, displaying an apparent dissociation constant (Kd) of 6.4 X 10(-8) M for this sterol.
T9 1173-1309 Sentence denotes Specific anti-human Cal-BP antisera were prepared in rabbits, and produced precipitate lines of identity between Cal-BP and human serum.
T10 1310-1580 Sentence denotes Specific binding of vitamin D3,25-OH-D3, and 1,25-(OH)2D3 by human serum was completely neutralized after immunoprecipitation of the serum with the gamma globulin fraction of anti-Cal-BP antiserum, indicating a common transport protein for these sterols in human plasma.
T11 1581-1752 Sentence denotes There was no immunological cross-reactivity between Cal-BP and rat or chicken sera, indicating that the Cal-BP in these three sera are immunologically completely distinct.
T12 1753-1926 Sentence denotes Purified human Cal-BP and human sera also produced lines of identity with commercial anti-human group-specific component (Gc) antisera in radial immunodiffusion experiments.
T13 1927-2069 Sentence denotes This finding supports an earlier report of the identity of calciferol/calcifidiol-binding protein and group-specific component in human serum.
T14 2070-2189 Sentence denotes The Cal-BP content of human serum is approximately 10(-5) M, whereas the calcifidiol content is approximately 10(-7) M.
T15 2190-2261 Sentence denotes Normally, the dominant moiety of human plasma Cal-BP is the apoprotein.
T1 0-46 Sentence denotes 25-Hydroxyvitamin D transport in human plasma.
T2 47-117 Sentence denotes Isolation and partial characterization of calcifidiol-binding protein.
T3 118-250 Sentence denotes The binding protein for 25-hydroxycholecalciferol (25-OH-D3 or calcifidiol) in human plasma has been purified from Cohn Fraction IV.
T4 251-490 Sentence denotes Following in vitro labeling with 25-OH-[3H]D3, the isolation sequence of procedures included: DEAE-cellulose chromatography; gel filtration on Sephadex G-200; chromatography on DEAE-Sephadex; preparative polyacrylamide gel electrophoresis.
T5 491-672 Sentence denotes These procedures resulted in a calcifidiol-binding protein (Cal-BP) which had been purified approximately 170-fold, and which was homogeneous by physical and immunological criteria.
T6 673-811 Sentence denotes The purified Cal-BP had inter-alpha mobility, a sedimentation constant (S20, w) of 3.46 S, and a molecular weight of approximately 59,000.
T7 812-1037 Sentence denotes Sucrose gradient ultracentrifugation of Cal-BP and ligand incubations indicated that there was apparently one binding site for either cholecalciferol, calcifidiol or 1,25-dihydroxycholecalciferol per molecule of human Cal-BP.
T8 1038-1172 Sentence denotes The protein had highest affinity for calcifidiol, displaying an apparent dissociation constant (Kd) of 6.4 X 10(-8) M for this sterol.
T9 1173-1309 Sentence denotes Specific anti-human Cal-BP antisera were prepared in rabbits, and produced precipitate lines of identity between Cal-BP and human serum.
T10 1310-1580 Sentence denotes Specific binding of vitamin D3,25-OH-D3, and 1,25-(OH)2D3 by human serum was completely neutralized after immunoprecipitation of the serum with the gamma globulin fraction of anti-Cal-BP antiserum, indicating a common transport protein for these sterols in human plasma.
T11 1581-1752 Sentence denotes There was no immunological cross-reactivity between Cal-BP and rat or chicken sera, indicating that the Cal-BP in these three sera are immunologically completely distinct.
T12 1753-1926 Sentence denotes Purified human Cal-BP and human sera also produced lines of identity with commercial anti-human group-specific component (Gc) antisera in radial immunodiffusion experiments.
T13 1927-2069 Sentence denotes This finding supports an earlier report of the identity of calciferol/calcifidiol-binding protein and group-specific component in human serum.
T14 2070-2189 Sentence denotes The Cal-BP content of human serum is approximately 10(-5) M, whereas the calcifidiol content is approximately 10(-7) M.
T15 2190-2261 Sentence denotes Normally, the dominant moiety of human plasma Cal-BP is the apoprotein.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 33-38 OrganismTaxon denotes human 9606
T2 197-202 OrganismTaxon denotes human 9606
T3 1024-1029 OrganismTaxon denotes human 9606
T4 1187-1192 OrganismTaxon denotes human 9606
T5 1226-1233 OrganismTaxon denotes rabbits 9986
T6 1297-1302 OrganismTaxon denotes human 9606
T7 1371-1376 OrganismTaxon denotes human 9606
T8 1567-1572 OrganismTaxon denotes human 9606
T9 1644-1647 OrganismTaxon denotes rat 10114|10116
T11 1762-1767 OrganismTaxon denotes human 9606
T12 1779-1784 OrganismTaxon denotes human 9606
T13 1843-1848 OrganismTaxon denotes human 9606
T14 2057-2062 OrganismTaxon denotes human 9606
T15 2092-2097 OrganismTaxon denotes human 9606
T16 2223-2228 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 39-45 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T2 203-209 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T3 1573-1579 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T4 2229-2235 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969