PubMed:8178155 JSONTXT

{"project":"AIMed","denotations":[{"id":"T1","span":{"begin":76,"end":98},"obj":"protein"},{"id":"T2","span":{"begin":286,"end":300},"obj":"protein"},{"id":"T3","span":{"begin":302,"end":307},"obj":"protein"},{"id":"T4","span":{"begin":404,"end":408},"obj":"protein"},{"id":"T5","span":{"begin":457,"end":461},"obj":"protein"},{"id":"T6","span":{"begin":508,"end":513},"obj":"protein"},{"id":"T7","span":{"begin":519,"end":524},"obj":"protein"},{"id":"T8","span":{"begin":551,"end":555},"obj":"protein"},{"id":"T9","span":{"begin":573,"end":578},"obj":"protein"},{"id":"T10","span":{"begin":602,"end":615},"obj":"protein"}],"text":"Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor.\nA cytokine was identified that stimulated the proliferation of T lymphocytes, and a complementary DNA clone encoding this new T cell growth factor was isolated. The cytokine, designated interleukin-15 (IL-15), is produced by a wide variety of cells and tissues and shares many biological properties with IL-2. Monoclonal antibodies to the beta chain of the IL-2 receptor inhibited the biological activity of IL-15, and IL-15 competed for binding with IL-2, indicating that IL-15 uses components of the IL-2 receptor."}