> top > docs > PubMed:8163464 > annotations

PubMed:8163464 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
T1 0-64 Sentence denotes A novel heterodimerization partner for thyroid hormone receptor.
T2 65-108 Sentence denotes Peroxisome proliferator-activated receptor.
T3 109-236 Sentence denotes Retinoid-like receptors play a central role in hormonal responses by forming heterodimers with other nuclear hormone receptors.
T4 237-429 Sentence denotes In this study we have identified the peroxisome proliferator-activated receptor (PPAR) as a new thyroid hormone receptor (THR) auxiliary nuclear protein, heterodimerizing with THR in solution.
T5 430-672 Sentence denotes Although these heterodimers do not recognize a classical thyroid hormone response element (TRE) characterized by direct repeat separated by four nucleotides (DR+4), PPAR behaves as a dominant negative regulator of thyroid hormone (TH) action.
T6 673-834 Sentence denotes However, a TH-dependent positive effect is elicited by selective interaction of the THR beta-PPAR but not the THR alpha-PPAR heterodimer with a novel TRE (DR+2).
T7 835-939 Sentence denotes The critical region of THR beta was mapped to 3 amino acids in the distal box of the DNA binding domain.
T8 940-1044 Sentence denotes Hence, PPAR can positively or negatively influence TH action depending on TRE structure and THR isotype.
T1 0-64 Sentence denotes A novel heterodimerization partner for thyroid hormone receptor.
T2 65-108 Sentence denotes Peroxisome proliferator-activated receptor.
T3 109-236 Sentence denotes Retinoid-like receptors play a central role in hormonal responses by forming heterodimers with other nuclear hormone receptors.
T4 237-429 Sentence denotes In this study we have identified the peroxisome proliferator-activated receptor (PPAR) as a new thyroid hormone receptor (THR) auxiliary nuclear protein, heterodimerizing with THR in solution.
T5 430-672 Sentence denotes Although these heterodimers do not recognize a classical thyroid hormone response element (TRE) characterized by direct repeat separated by four nucleotides (DR+4), PPAR behaves as a dominant negative regulator of thyroid hormone (TH) action.
T6 673-834 Sentence denotes However, a TH-dependent positive effect is elicited by selective interaction of the THR beta-PPAR but not the THR alpha-PPAR heterodimer with a novel TRE (DR+2).
T7 835-939 Sentence denotes The critical region of THR beta was mapped to 3 amino acids in the distal box of the DNA binding domain.
T8 940-1044 Sentence denotes Hence, PPAR can positively or negatively influence TH action depending on TRE structure and THR isotype.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 39-46 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T2 333-340 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T3 487-494 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T4 644-651 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 8-34 protein denotes heterodimerization partner
T2 39-63 protein denotes thyroid hormone receptor
T3 65-107 protein denotes Peroxisome proliferator-activated receptor
T4 109-132 protein denotes Retinoid-like receptors
T5 186-198 protein denotes heterodimers
T6 210-235 protein denotes nuclear hormone receptors
T7 274-316 protein denotes peroxisome proliferator-activated receptor
T8 318-322 protein denotes PPAR
T9 333-389 protein denotes thyroid hormone receptor (THR) auxiliary nuclear protein
T10 413-416 protein denotes THR
T11 445-457 protein denotes heterodimers
T12 487-519 DNA denotes thyroid hormone response element
T13 521-524 DNA denotes TRE
T14 588-592 DNA denotes DR+4
T15 595-599 protein denotes PPAR
T16 757-770 protein denotes THR beta-PPAR
T17 783-809 protein denotes THR alpha-PPAR heterodimer
T18 823-826 DNA denotes TRE
T19 828-832 DNA denotes DR+2
T20 858-861 protein denotes THR
T21 902-912 protein denotes distal box
T22 920-938 protein denotes DNA binding domain
T23 947-951 protein denotes PPAR
T24 1014-1017 DNA denotes TRE
T25 1032-1043 protein denotes THR isotype

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-34 NP denotes A novel heterodimerization partner
C2 39-63 NP denotes thyroid hormone receptor
C3 65-107 NP denotes Peroxisome proliferator-activated receptor
C4 186-198 NP denotes heterodimers
C5 270-323 NP denotes the peroxisome proliferator-activated receptor (PPAR)
C6 327-389 NP denotes a new thyroid hormone receptor (THR) auxiliary nuclear protein
C7 413-416 NP denotes THR
C8 439-457 NP denotes these heterodimers
C9 595-599 NP denotes PPAR
C10 644-671 NP denotes thyroid hormone (TH) action
C11 753-770 NP denotes the THR beta-PPAR
C12 858-866 NP denotes THR beta
C13 947-951 NP denotes PPAR
C14 991-1000 NP denotes TH action
R1 C3 C1 coref-ident Peroxisome proliferator-activated receptor,A novel heterodimerization partner
R2 C5 C3 coref-ident the peroxisome proliferator-activated receptor (PPAR),Peroxisome proliferator-activated receptor
R3 C6 C5 coref-ident a new thyroid hormone receptor (THR) auxiliary nuclear protein,the peroxisome proliferator-activated receptor (PPAR)
R4 C7 C2 coref-ident THR,thyroid hormone receptor
R5 C8 C4 coref-ident these heterodimers,heterodimers
R6 C9 C5 coref-ident PPAR,the peroxisome proliferator-activated receptor (PPAR)
R7 C12 C11 coref-ident THR beta,the THR beta-PPAR
R8 C13 C9 coref-ident PPAR,PPAR
R9 C14 C10 coref-ident TH action,thyroid hormone (TH) action

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-64 Sentence denotes A novel heterodimerization partner for thyroid hormone receptor.
S2 65-108 Sentence denotes Peroxisome proliferator-activated receptor.
S3 109-236 Sentence denotes Retinoid-like receptors play a central role in hormonal responses by forming heterodimers with other nuclear hormone receptors.
S4 237-429 Sentence denotes In this study we have identified the peroxisome proliferator-activated receptor (PPAR) as a new thyroid hormone receptor (THR) auxiliary nuclear protein, heterodimerizing with THR in solution.
S5 430-672 Sentence denotes Although these heterodimers do not recognize a classical thyroid hormone response element (TRE) characterized by direct repeat separated by four nucleotides (DR+4), PPAR behaves as a dominant negative regulator of thyroid hormone (TH) action.
S6 673-834 Sentence denotes However, a TH-dependent positive effect is elicited by selective interaction of the THR beta-PPAR but not the THR alpha-PPAR heterodimer with a novel TRE (DR+2).
S7 835-939 Sentence denotes The critical region of THR beta was mapped to 3 amino acids in the distal box of the DNA binding domain.
S8 940-1044 Sentence denotes Hence, PPAR can positively or negatively influence TH action depending on TRE structure and THR isotype.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 8-34 protein_family_or_group denotes heterodimerization partner
T2 39-63 protein_family_or_group denotes thyroid hormone receptor
T3 65-107 protein_molecule denotes Peroxisome proliferator-activated receptor
T4 109-132 protein_family_or_group denotes Retinoid-like receptors
T5 156-174 other_name denotes hormonal responses
T6 186-198 protein_complex denotes heterodimers
T7 210-235 protein_family_or_group denotes nuclear hormone receptors
T8 274-316 protein_molecule denotes peroxisome proliferator-activated receptor
T9 318-322 protein_molecule denotes PPAR
T10 333-357 protein_family_or_group denotes thyroid hormone receptor
T11 359-362 protein_family_or_group denotes THR
T12 413-416 protein_family_or_group denotes THR
T13 445-457 protein_complex denotes heterodimers
T14 487-519 DNA_domain_or_region denotes thyroid hormone response element
T15 521-524 DNA_domain_or_region denotes TRE
T16 543-556 DNA_substructure denotes direct repeat
T17 570-586 nucleotide denotes four nucleotides
T18 588-592 DNA_domain_or_region denotes DR+4
T19 595-599 protein_molecule denotes PPAR
T20 613-640 other_name denotes dominant negative regulator
T21 644-659 peptide denotes thyroid hormone
T22 661-663 peptide denotes TH
T23 684-686 peptide denotes TH
T24 757-760 protein_family_or_group denotes THR
T25 766-770 protein_molecule denotes PPAR
T26 783-786 protein_family_or_group denotes THR
T27 793-797 protein_molecule denotes PPAR
T28 823-826 DNA_domain_or_region denotes TRE
T29 828-832 DNA_domain_or_region denotes DR+2
T30 858-861 protein_family_or_group denotes THR
T31 883-894 amino_acid_monomer denotes amino acids
T32 920-938 protein_domain_or_region denotes DNA binding domain
T33 947-951 protein_molecule denotes PPAR
T34 991-993 peptide denotes TH
T35 1014-1017 DNA_domain_or_region denotes TRE
T36 1032-1035 protein_family_or_group denotes THR

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 39-46 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T2 333-340 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T3 487-494 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T4 644-651 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 39-46 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T2 333-340 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T3 487-494 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T4 644-651 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046