PubMed:8126348 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	19-42	cell_type	denotes	senescent T lymphocytes
T2	52-57	protein	denotes	hsp70
T3	101-138	cell_line	denotes	Senescent human T lymphocyte cultures
T4	204-223	cell_line	denotes	early passage cells
T5	296-313	cell_line	denotes	senescent T cells
T6	343-348	protein	denotes	hsp70
T7	468-496	DNA	denotes	consensus heat shock element
T8	567-583	cell_line	denotes	cultured T cells
T9	747-764	cell_type	denotes	senescent T cells
T10	823-828	protein	denotes	hsp70

Id	Subject	Object	Predicate	Lexical cue
S1	0-100	Sentence	denotes	Stress response of senescent T lymphocytes: reduced hsp70 is independent of the proliferative block.
S2	101-275	Sentence	denotes	Senescent human T lymphocyte cultures are unable to undergo proliferation, but show no difference from early passage cells in cytotoxic function or surface antigenic profile.
S3	276-386	Sentence	denotes	A second feature of senescent T cells is the dramatic reduction in hsp70 production in response to heat shock.
S4	387-497	Sentence	denotes	This decline is associated with a decrease in binding of nuclear extracts to the consensus heat shock element.
S5	498-723	Sentence	denotes	Interestingly, the progressive decline in the heat shock response of cultured T cells correlates with the percent proliferative life span completed rather than with the actual proliferative activity at the time of heat shock.
S6	724-1026	Sentence	denotes	This suggests that for senescent T cells the reduced ability to respond to heat shock by producing hsp70, although possibly lying at the level of transcriptional control, may nevertheless be unrelated to the reduced DNA synthesis or the diminished proliferative activity also manifested by these cells.

Id	Subject	Object	Predicate	Lexical cue
C1	19-42	NP	denotes	senescent T lymphocytes
C2	296-313	NP	denotes	senescent T cells
C3	375-385	NP	denotes	heat shock
C4	567-583	NP	denotes	cultured T cells
C5	712-722	NP	denotes	heat shock
C6	747-764	NP	denotes	senescent T cells
C7	799-809	NP	denotes	heat shock
C8	1014-1025	NP	denotes	these cells
R1	C2	C1	coref-ident	senescent T cells,senescent T lymphocytes
R2	C4	C2	coref-ident	cultured T cells,senescent T cells
R3	C5	C3	coref-ident	heat shock,heat shock
R4	C6	C2	coref-ident	senescent T cells,senescent T cells
R5	C7	C5	coref-ident	heat shock,heat shock
R6	C8	C6	coref-ident	these cells,senescent T cells

Id	Subject	Object	Predicate	Lexical cue
T1	0-15	other_name	denotes	Stress response
T2	19-42	cell_type	denotes	senescent T lymphocytes
T3	52-57	protein_molecule	denotes	hsp70
T4	80-99	other_name	denotes	proliferative block
T5	101-138	cell_line	denotes	Senescent human T lymphocyte cultures
T6	204-223	cell_line	denotes	early passage cells
T7	227-245	other_name	denotes	cytotoxic function
T8	249-274	other_name	denotes	surface antigenic profile
T9	296-313	cell_line	denotes	senescent T cells
T10	343-348	protein_molecule	denotes	hsp70
T11	375-385	other_name	denotes	heat shock
T12	444-460	cell_component	denotes	nuclear extracts
T13	468-477	DNA_domain_or_region	denotes	consensus
T14	478-488	other_name	denotes	heat shock
T15	544-554	other_name	denotes	heat shock
T16	567-583	cell_line	denotes	cultured T cells
T17	612-635	other_name	denotes	proliferative life span
T18	674-696	other_name	denotes	proliferative activity
T19	712-722	other_name	denotes	heat shock
T20	747-764	cell_type	denotes	senescent T cells
T21	799-809	other_name	denotes	heat shock
T22	823-828	protein_molecule	denotes	hsp70
T23	870-893	other_name	denotes	transcriptional control
T24	932-939	other_name	denotes	reduced
T25	940-943	DNA_N/A	denotes	DNA
T26	961-994	other_name	denotes	diminished proliferative activity