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PubMed:809437 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-100 Sentence denotes Modification of bovine alpha-lactalbumin with N-bromosuccinimide and 2-hydroxy-5-nitrobenzylbromide.
T2 101-301 Sentence denotes Reaction of alpha-lactalbumin at pH 7 in aqueous solution with either 2-hydroxy-5-nitrobenzylbromide or N-bromosuccinimide yields derivatives in which only 2 of the 4 tryptophan residues are modified.
T3 302-385 Sentence denotes All 4 residues of tryptophan are modified under the similar conditions in 8 M urea.
T4 386-565 Sentence denotes Structural analysis of the modified derivatives revealed that tryptophans 26 and 118 are the sole reactive residues and that tryptophan 118 reacts more rapidly than tryptophan 26.
T5 566-767 Sentence denotes The fluorescence of alpha-lactalbumin modified to varying extents with N-bromosuccinimide indicates that tryptophan 118 is exposed to solvent whereas tryptophan 26 is in a more hydrophobic environment.
T6 768-964 Sentence denotes The chemical reactivities and fluorescence properties of tryptophans 26 and 118 are consistent with the proposed conformations of alpha-lactalbumin based on its similarity with egg white lysozyme.
T7 965-1275 Sentence denotes The kinetic properties of both derivatives of alpha-lactalbumin containing up to 2 modified residues indicate that each derivative has decreased affinity for the galactosyltransferase but that at saturating concentrations, Km and Vmax for lactose synthesis are unchanged from those of native alpha-lactalbumin.
T1 0-100 Sentence denotes Modification of bovine alpha-lactalbumin with N-bromosuccinimide and 2-hydroxy-5-nitrobenzylbromide.
T2 101-301 Sentence denotes Reaction of alpha-lactalbumin at pH 7 in aqueous solution with either 2-hydroxy-5-nitrobenzylbromide or N-bromosuccinimide yields derivatives in which only 2 of the 4 tryptophan residues are modified.
T3 302-385 Sentence denotes All 4 residues of tryptophan are modified under the similar conditions in 8 M urea.
T4 386-565 Sentence denotes Structural analysis of the modified derivatives revealed that tryptophans 26 and 118 are the sole reactive residues and that tryptophan 118 reacts more rapidly than tryptophan 26.
T5 566-767 Sentence denotes The fluorescence of alpha-lactalbumin modified to varying extents with N-bromosuccinimide indicates that tryptophan 118 is exposed to solvent whereas tryptophan 26 is in a more hydrophobic environment.
T6 768-964 Sentence denotes The chemical reactivities and fluorescence properties of tryptophans 26 and 118 are consistent with the proposed conformations of alpha-lactalbumin based on its similarity with egg white lysozyme.
T7 965-1275 Sentence denotes The kinetic properties of both derivatives of alpha-lactalbumin containing up to 2 modified residues indicate that each derivative has decreased affinity for the galactosyltransferase but that at saturating concentrations, Km and Vmax for lactose synthesis are unchanged from those of native alpha-lactalbumin.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 945-948 http://purl.obolibrary.org/obo/MAT_0000213 denotes egg

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1204-1211 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 16-22 OrganismTaxon denotes bovine 9913

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 479-483 Body_part denotes sole http://purl.obolibrary.org/obo/UBERON_0008338
T2 945-954 Body_part denotes egg white http://purl.obolibrary.org/obo/UBERON_0008944

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 945-948 Body_part denotes egg http://purl.obolibrary.org/obo/MAT_0000213

sentences

Id Subject Object Predicate Lexical cue
T1 0-100 Sentence denotes Modification of bovine alpha-lactalbumin with N-bromosuccinimide and 2-hydroxy-5-nitrobenzylbromide.
T2 101-301 Sentence denotes Reaction of alpha-lactalbumin at pH 7 in aqueous solution with either 2-hydroxy-5-nitrobenzylbromide or N-bromosuccinimide yields derivatives in which only 2 of the 4 tryptophan residues are modified.
T3 302-385 Sentence denotes All 4 residues of tryptophan are modified under the similar conditions in 8 M urea.
T4 386-565 Sentence denotes Structural analysis of the modified derivatives revealed that tryptophans 26 and 118 are the sole reactive residues and that tryptophan 118 reacts more rapidly than tryptophan 26.
T5 566-767 Sentence denotes The fluorescence of alpha-lactalbumin modified to varying extents with N-bromosuccinimide indicates that tryptophan 118 is exposed to solvent whereas tryptophan 26 is in a more hydrophobic environment.
T6 768-964 Sentence denotes The chemical reactivities and fluorescence properties of tryptophans 26 and 118 are consistent with the proposed conformations of alpha-lactalbumin based on its similarity with egg white lysozyme.
T7 965-1275 Sentence denotes The kinetic properties of both derivatives of alpha-lactalbumin containing up to 2 modified residues indicate that each derivative has decreased affinity for the galactosyltransferase but that at saturating concentrations, Km and Vmax for lactose synthesis are unchanged from those of native alpha-lactalbumin.
T1 0-100 Sentence denotes Modification of bovine alpha-lactalbumin with N-bromosuccinimide and 2-hydroxy-5-nitrobenzylbromide.
T2 101-301 Sentence denotes Reaction of alpha-lactalbumin at pH 7 in aqueous solution with either 2-hydroxy-5-nitrobenzylbromide or N-bromosuccinimide yields derivatives in which only 2 of the 4 tryptophan residues are modified.
T3 302-385 Sentence denotes All 4 residues of tryptophan are modified under the similar conditions in 8 M urea.
T4 386-565 Sentence denotes Structural analysis of the modified derivatives revealed that tryptophans 26 and 118 are the sole reactive residues and that tryptophan 118 reacts more rapidly than tryptophan 26.
T5 566-767 Sentence denotes The fluorescence of alpha-lactalbumin modified to varying extents with N-bromosuccinimide indicates that tryptophan 118 is exposed to solvent whereas tryptophan 26 is in a more hydrophobic environment.
T6 768-964 Sentence denotes The chemical reactivities and fluorescence properties of tryptophans 26 and 118 are consistent with the proposed conformations of alpha-lactalbumin based on its similarity with egg white lysozyme.
T7 965-1275 Sentence denotes The kinetic properties of both derivatives of alpha-lactalbumin containing up to 2 modified residues indicate that each derivative has decreased affinity for the galactosyltransferase but that at saturating concentrations, Km and Vmax for lactose synthesis are unchanged from those of native alpha-lactalbumin.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 16-22 OrganismTaxon denotes bovine 9913

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-100 Sentence denotes Modification of bovine alpha-lactalbumin with N-bromosuccinimide and 2-hydroxy-5-nitrobenzylbromide.
T2 101-301 Sentence denotes Reaction of alpha-lactalbumin at pH 7 in aqueous solution with either 2-hydroxy-5-nitrobenzylbromide or N-bromosuccinimide yields derivatives in which only 2 of the 4 tryptophan residues are modified.
T3 302-385 Sentence denotes All 4 residues of tryptophan are modified under the similar conditions in 8 M urea.
T4 386-565 Sentence denotes Structural analysis of the modified derivatives revealed that tryptophans 26 and 118 are the sole reactive residues and that tryptophan 118 reacts more rapidly than tryptophan 26.
T5 566-767 Sentence denotes The fluorescence of alpha-lactalbumin modified to varying extents with N-bromosuccinimide indicates that tryptophan 118 is exposed to solvent whereas tryptophan 26 is in a more hydrophobic environment.
T6 768-964 Sentence denotes The chemical reactivities and fluorescence properties of tryptophans 26 and 118 are consistent with the proposed conformations of alpha-lactalbumin based on its similarity with egg white lysozyme.
T7 965-1275 Sentence denotes The kinetic properties of both derivatives of alpha-lactalbumin containing up to 2 modified residues indicate that each derivative has decreased affinity for the galactosyltransferase but that at saturating concentrations, Km and Vmax for lactose synthesis are unchanged from those of native alpha-lactalbumin.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1204-1211 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 479-483 Body_part denotes sole http://purl.obolibrary.org/obo/UBERON_0008338
T2 945-954 Body_part denotes egg white http://purl.obolibrary.org/obo/UBERON_0008944

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 945-948 Body_part denotes egg http://purl.obolibrary.org/obo/MAT_0000213