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PubMed:809436 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-65 Sentence denotes Ribonucleoside diphosphate reductase induced by bacteriophage T4.
T2 66-70 Sentence denotes III.
T3 71-124 Sentence denotes Isolation and characterization of proteins B1 and B2.
T4 125-314 Sentence denotes Ribonucleoside diphosphate reductase determined by bacteriophage T4 consists of a tight complex (alpha2beta2) of the polypeptide chains alpha (Mr = 80,000 to 85,000) and beta (Mr = 35,000).
T5 315-554 Sentence denotes The alpha2 dimer (= protein B1) was purified from Escherichia coli B infected with T4 mutant nrdB55 (Yeh, Y.C., and Tessman, I. (1972) Virology 47, 767-772) which carries an amber mutation in the gene coding for the beta polypeptide chain.
T6 555-640 Sentence denotes Protein B1 contained binding sites for dATP, an allosteric effector of the reductase.
T7 641-825 Sentence denotes The beta2 dimer (= protein B2) was purified by selective desorption with 1 M guanidine HCl from a dATP-Sepharose affinity column containing adsorbed native T4 ribonucleotide reductase.
T8 826-975 Sentence denotes Protein B2, isolated this way, was enzymatically inactive due to partial loss of its iron but it could be reactivated by treatment with ferrous iron.
T9 976-1151 Sentence denotes Active protein B2 contained two atoms of non-heme iron per molecule and exhibited the optical and electron spin resonance spectra previously demonstrated in the native enzyme.
T10 1152-1279 Sentence denotes The T4-induced proteins B1 and B2 were unable to reduce ribonucleotides when assayed separately but were active in combination.
T11 1280-1470 Sentence denotes The proteins did not form catalytically functional hybrids with proteins B1 and B2 of Escherichia coli ribonucleotide reductase, neither did they cross-react immunologically with the latter.
T12 1471-1661 Sentence denotes 5-Hydroxymethyl-dCTP, at concentrations above 10 muM, was a positive allosteric effector of T4 ribonucleotide reductase promoting the reduction of the pyrimidine ribonucleotides CDP and UDP.
T13 1662-1731 Sentence denotes The nucleotide had little effect on E. coli ribonucleotide reductase.
T1 0-65 Sentence denotes Ribonucleoside diphosphate reductase induced by bacteriophage T4.
T2 66-70 Sentence denotes III.
T3 71-124 Sentence denotes Isolation and characterization of proteins B1 and B2.
T4 125-314 Sentence denotes Ribonucleoside diphosphate reductase determined by bacteriophage T4 consists of a tight complex (alpha2beta2) of the polypeptide chains alpha (Mr = 80,000 to 85,000) and beta (Mr = 35,000).
T5 315-554 Sentence denotes The alpha2 dimer (= protein B1) was purified from Escherichia coli B infected with T4 mutant nrdB55 (Yeh, Y.C., and Tessman, I. (1972) Virology 47, 767-772) which carries an amber mutation in the gene coding for the beta polypeptide chain.
T6 555-640 Sentence denotes Protein B1 contained binding sites for dATP, an allosteric effector of the reductase.
T7 641-825 Sentence denotes The beta2 dimer (= protein B2) was purified by selective desorption with 1 M guanidine HCl from a dATP-Sepharose affinity column containing adsorbed native T4 ribonucleotide reductase.
T8 826-975 Sentence denotes Protein B2, isolated this way, was enzymatically inactive due to partial loss of its iron but it could be reactivated by treatment with ferrous iron.
T9 976-1151 Sentence denotes Active protein B2 contained two atoms of non-heme iron per molecule and exhibited the optical and electron spin resonance spectra previously demonstrated in the native enzyme.
T10 1152-1279 Sentence denotes The T4-induced proteins B1 and B2 were unable to reduce ribonucleotides when assayed separately but were active in combination.
T11 1280-1470 Sentence denotes The proteins did not form catalytically functional hybrids with proteins B1 and B2 of Escherichia coli ribonucleotide reductase, neither did they cross-react immunologically with the latter.
T12 1471-1661 Sentence denotes 5-Hydroxymethyl-dCTP, at concentrations above 10 muM, was a positive allosteric effector of T4 ribonucleotide reductase promoting the reduction of the pyrimidine ribonucleotides CDP and UDP.
T13 1662-1731 Sentence denotes The nucleotide had little effect on E. coli ribonucleotide reductase.

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1649-1652 Disease denotes CDP http://purl.obolibrary.org/obo/MONDO_0019701

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 365-381 OrganismTaxon denotes Escherichia coli 562
T2 1366-1382 OrganismTaxon denotes Escherichia coli 562
T3 1698-1705 OrganismTaxon denotes E. coli 562