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PubMed:808542 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 272-281 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T3 469-478 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T5 575-584 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T7 664-673 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T9 740-749 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T11 771-780 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T13 930-939 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T15 1336-1345 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T17 1483-1492 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE

sentences

Id Subject Object Predicate Lexical cue
T1 0-91 Sentence denotes On the interaction of alpha-lactalbumin and galactosyltransferase during lactose synthesis.
T2 92-396 Sentence denotes The regulatory effect of alpha-lactalbumin in the lactose synthase system has been ascribed to its reversible association with a complex of galactosyltransferase with Mn2+ and UDP-galactose, prior to the binding of monosaccharides; the resulting complex has a higher affinity for various monosaccharides.
T3 397-624 Sentence denotes Two steps in the postulated catalytic cycle have been investigated; UDP-galactose binding to enzyme-Mn2+ by equilibrium dialysis and alpha-lactalbumin binding to enzyme-Mn2+-UDP-galactose by sedimentation velocity and kinetics.
T4 625-818 Sentence denotes There is a single binding site for UDP-galactose on the enzyme-Mn2+ complex, and the dissociation constant for UDP-galactose from enzyme-Mn2+-UDP-galactose was found to be 72 muM at 37 degrees.
T5 819-1266 Sentence denotes The formation of a complex between galactosyltransferase and alpha-lactalbumin in the presence of Mn2+ and UDP-galactose was observed as an increase in sedimentation coefficient of enzyme activity So20,w from 3.25 +/- 0.03 in the absence of alpha-lactalbumin to 4.22 +/- 0.03 at saturating concentrations of alpha-lactalbumin, a value closely similar to that of a cross-linked 1:1 complex of the proteins under the same conditions (4.35 +/- 0.03).
T6 1267-1355 Sentence denotes No interaction was observed in the absence of substrates or with UDP-galactose and EDTA.
T7 1356-1583 Sentence denotes From the ultracentrifuge data and steady state kinetics, dissociation constants for alpha-lactalbumin from the enzyme-Mn2+-UDP-galactose-alpha-lactalbumin complex were determined at several temperatures and salt concentrations.
T8 1584-1621 Sentence denotes These showed good internal agreement.
T9 1622-1791 Sentence denotes The free energy change delta G degrees for the association of the two proteins is calculated, and the results are discussed in relation to the nature of the interaction.
T1 0-91 Sentence denotes On the interaction of alpha-lactalbumin and galactosyltransferase during lactose synthesis.
T2 92-396 Sentence denotes The regulatory effect of alpha-lactalbumin in the lactose synthase system has been ascribed to its reversible association with a complex of galactosyltransferase with Mn2+ and UDP-galactose, prior to the binding of monosaccharides; the resulting complex has a higher affinity for various monosaccharides.
T3 397-624 Sentence denotes Two steps in the postulated catalytic cycle have been investigated; UDP-galactose binding to enzyme-Mn2+ by equilibrium dialysis and alpha-lactalbumin binding to enzyme-Mn2+-UDP-galactose by sedimentation velocity and kinetics.
T4 625-818 Sentence denotes There is a single binding site for UDP-galactose on the enzyme-Mn2+ complex, and the dissociation constant for UDP-galactose from enzyme-Mn2+-UDP-galactose was found to be 72 muM at 37 degrees.
T5 819-1266 Sentence denotes The formation of a complex between galactosyltransferase and alpha-lactalbumin in the presence of Mn2+ and UDP-galactose was observed as an increase in sedimentation coefficient of enzyme activity So20,w from 3.25 +/- 0.03 in the absence of alpha-lactalbumin to 4.22 +/- 0.03 at saturating concentrations of alpha-lactalbumin, a value closely similar to that of a cross-linked 1:1 complex of the proteins under the same conditions (4.35 +/- 0.03).
T6 1267-1355 Sentence denotes No interaction was observed in the absence of substrates or with UDP-galactose and EDTA.
T7 1356-1583 Sentence denotes From the ultracentrifuge data and steady state kinetics, dissociation constants for alpha-lactalbumin from the enzyme-Mn2+-UDP-galactose-alpha-lactalbumin complex were determined at several temperatures and salt concentrations.
T8 1584-1621 Sentence denotes These showed good internal agreement.
T9 1622-1791 Sentence denotes The free energy change delta G degrees for the association of the two proteins is calculated, and the results are discussed in relation to the nature of the interaction.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 272-281 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T2 272-281 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T3 469-478 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T4 469-478 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T5 575-584 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T6 575-584 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T7 664-673 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T8 664-673 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T9 740-749 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T10 740-749 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T11 771-780 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T12 771-780 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T13 930-939 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T14 930-939 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T15 1336-1345 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T16 1336-1345 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T17 1483-1492 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T18 1483-1492 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 73-80 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T2 142-149 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 73-80 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T2 142-149 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1645-1650 Cell denotes delta http://purl.obolibrary.org/obo/CL:0004124

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 517-525 Organism denotes dialysis 124307

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-91 Sentence denotes On the interaction of alpha-lactalbumin and galactosyltransferase during lactose synthesis.
T2 92-396 Sentence denotes The regulatory effect of alpha-lactalbumin in the lactose synthase system has been ascribed to its reversible association with a complex of galactosyltransferase with Mn2+ and UDP-galactose, prior to the binding of monosaccharides; the resulting complex has a higher affinity for various monosaccharides.
T3 397-624 Sentence denotes Two steps in the postulated catalytic cycle have been investigated; UDP-galactose binding to enzyme-Mn2+ by equilibrium dialysis and alpha-lactalbumin binding to enzyme-Mn2+-UDP-galactose by sedimentation velocity and kinetics.
T4 625-818 Sentence denotes There is a single binding site for UDP-galactose on the enzyme-Mn2+ complex, and the dissociation constant for UDP-galactose from enzyme-Mn2+-UDP-galactose was found to be 72 muM at 37 degrees.
T5 819-1266 Sentence denotes The formation of a complex between galactosyltransferase and alpha-lactalbumin in the presence of Mn2+ and UDP-galactose was observed as an increase in sedimentation coefficient of enzyme activity So20,w from 3.25 +/- 0.03 in the absence of alpha-lactalbumin to 4.22 +/- 0.03 at saturating concentrations of alpha-lactalbumin, a value closely similar to that of a cross-linked 1:1 complex of the proteins under the same conditions (4.35 +/- 0.03).
T6 1267-1355 Sentence denotes No interaction was observed in the absence of substrates or with UDP-galactose and EDTA.
T7 1356-1583 Sentence denotes From the ultracentrifuge data and steady state kinetics, dissociation constants for alpha-lactalbumin from the enzyme-Mn2+-UDP-galactose-alpha-lactalbumin complex were determined at several temperatures and salt concentrations.
T8 1584-1621 Sentence denotes These showed good internal agreement.
T9 1622-1791 Sentence denotes The free energy change delta G degrees for the association of the two proteins is calculated, and the results are discussed in relation to the nature of the interaction.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 517-525 OrganismTaxon denotes dialysis 124307

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1645-1650 Cell denotes delta http://purl.obolibrary.org/obo/CL:0004124