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PubMed:8051172 JSONTXT

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CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 34-40 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T2 86-92 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T3 288-301 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T4 498-511 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T5 645-651 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T6 832-838 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084

sentences

Id Subject Object Predicate Lexical cue
T1 0-113 Sentence denotes ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.
T2 114-250 Sentence denotes Several mammalian responses to UV irradiation, including the activation of NF-kappa B, are believed to involve tyrosine phosphorylation.
T3 251-418 Sentence denotes UV irradiation and H2O2 treatment of T lymphocytes induce protein tyrosine phosphorylation and Ca2+ signals similar to those observed following biological stimulation.
T4 419-490 Sentence denotes We have examined the role of cell surface molecules in these responses.
T5 491-626 Sentence denotes Normal T lymphocytes whose surface expression of CD3 was depleted showed impaired UV-induced tyrosine phosphorylation and Ca2+ signals.
T6 627-726 Sentence denotes Similarly, Jurkat T cell lines deficient in CD3 or CD45 expression also gave impaired UV responses.
T7 727-827 Sentence denotes However, all these cell types still gave strong Ca2+ and tyrosine phosphorylation responses to H2O2.
T8 828-921 Sentence denotes The T cell tyrosine kinase ZAP-70 was found to be highly responsive to UV and H2O2 treatment.
T9 922-1047 Sentence denotes ZAP-70 responsiveness to UV required expression of both CD3 and CD45, whereas only CD3 was required for the response to H2O2.
T10 1048-1201 Sentence denotes UV-induced activation of NF-kappa B was blocked by CD3 depletion, indicating the importance of such cell surface molecules in biological responses to UV.
T11 1202-1339 Sentence denotes In nonlymphoid cells, the epidermal growth factor receptor displayed increased tyrosine phosphorylation within seconds of UV irradiation.
T12 1340-1544 Sentence denotes These results suggest that UV-induced signal transduction is mediated via cell surface receptors that normally respond to biological stimulation, whereas H2O2 is able to partially bypass this requirement.
T1 0-113 Sentence denotes ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.
T2 114-250 Sentence denotes Several mammalian responses to UV irradiation, including the activation of NF-kappa B, are believed to involve tyrosine phosphorylation.
T3 251-418 Sentence denotes UV irradiation and H2O2 treatment of T lymphocytes induce protein tyrosine phosphorylation and Ca2+ signals similar to those observed following biological stimulation.
T4 419-490 Sentence denotes We have examined the role of cell surface molecules in these responses.
T5 491-626 Sentence denotes Normal T lymphocytes whose surface expression of CD3 was depleted showed impaired UV-induced tyrosine phosphorylation and Ca2+ signals.
T6 627-726 Sentence denotes Similarly, Jurkat T cell lines deficient in CD3 or CD45 expression also gave impaired UV responses.
T7 727-827 Sentence denotes However, all these cell types still gave strong Ca2+ and tyrosine phosphorylation responses to H2O2.
T8 828-921 Sentence denotes The T cell tyrosine kinase ZAP-70 was found to be highly responsive to UV and H2O2 treatment.
T9 922-1047 Sentence denotes ZAP-70 responsiveness to UV required expression of both CD3 and CD45, whereas only CD3 was required for the response to H2O2.
T10 1048-1201 Sentence denotes UV-induced activation of NF-kappa B was blocked by CD3 depletion, indicating the importance of such cell surface molecules in biological responses to UV.
T11 1202-1339 Sentence denotes In nonlymphoid cells, the epidermal growth factor receptor displayed increased tyrosine phosphorylation within seconds of UV irradiation.
T12 1340-1544 Sentence denotes These results suggest that UV-induced signal transduction is mediated via cell surface receptors that normally respond to biological stimulation, whereas H2O2 is able to partially bypass this requirement.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-22 protein denotes ZAP-70 tyrosine kinase
T2 24-28 protein denotes CD45
T3 34-49 protein denotes T cell receptor
T4 189-199 protein denotes NF-kappa B
T5 288-301 cell_type denotes T lymphocytes
T6 498-511 cell_type denotes T lymphocytes
T7 540-543 protein denotes CD3
T8 638-657 cell_line denotes Jurkat T cell lines
T9 848-861 protein denotes kinase ZAP-70
T10 922-928 protein denotes ZAP-70
T11 978-981 protein denotes CD3
T12 986-990 protein denotes CD45
T13 1005-1008 protein denotes CD3
T14 1073-1083 protein denotes NF-kappa B
T15 1099-1102 protein denotes CD3
T16 1148-1170 protein denotes cell surface molecules
T17 1205-1222 cell_type denotes nonlymphoid cells
T18 1228-1260 protein denotes epidermal growth factor receptor
T19 1414-1436 protein denotes cell surface receptors

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-113 Sentence denotes ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.
S2 114-250 Sentence denotes Several mammalian responses to UV irradiation, including the activation of NF-kappa B, are believed to involve tyrosine phosphorylation.
S3 251-418 Sentence denotes UV irradiation and H2O2 treatment of T lymphocytes induce protein tyrosine phosphorylation and Ca2+ signals similar to those observed following biological stimulation.
S4 419-490 Sentence denotes We have examined the role of cell surface molecules in these responses.
S5 491-626 Sentence denotes Normal T lymphocytes whose surface expression of CD3 was depleted showed impaired UV-induced tyrosine phosphorylation and Ca2+ signals.
S6 627-726 Sentence denotes Similarly, Jurkat T cell lines deficient in CD3 or CD45 expression also gave impaired UV responses.
S7 727-827 Sentence denotes However, all these cell types still gave strong Ca2+ and tyrosine phosphorylation responses to H2O2.
S8 828-921 Sentence denotes The T cell tyrosine kinase ZAP-70 was found to be highly responsive to UV and H2O2 treatment.
S9 922-1047 Sentence denotes ZAP-70 responsiveness to UV required expression of both CD3 and CD45, whereas only CD3 was required for the response to H2O2.
S10 1048-1201 Sentence denotes UV-induced activation of NF-kappa B was blocked by CD3 depletion, indicating the importance of such cell surface molecules in biological responses to UV.
S11 1202-1339 Sentence denotes In nonlymphoid cells, the epidermal growth factor receptor displayed increased tyrosine phosphorylation within seconds of UV irradiation.
S12 1340-1544 Sentence denotes These results suggest that UV-induced signal transduction is mediated via cell surface receptors that normally respond to biological stimulation, whereas H2O2 is able to partially bypass this requirement.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-22 NP denotes ZAP-70 tyrosine kinase
C2 65-112 NP denotes UV- and H2O2-induced T cell signal transduction
C4 145-159 NP denotes UV irradiation
C3 114-159 NP denotes Several mammalian responses to UV irradiation
C5 171-199 NP denotes the activation of NF-kappa B
C6 225-249 NP denotes tyrosine phosphorylation
C7 251-265 NP denotes UV irradiation
C9 309-341 NP denotes protein tyrosine phosphorylation
C8 309-358 NP denotes protein tyrosine phosphorylation and Ca2+ signals
C10 370-375 NP denotes those
C11 448-470 NP denotes cell surface molecules
C12 474-489 NP denotes these responses
C13 491-511 NP denotes Normal T lymphocytes
C14 512-517 NP denotes whose
C15 540-543 NP denotes CD3
C16 671-693 NP denotes CD3 or CD45 expression
C17 736-756 NP denotes all these cell types
C18 822-826 NP denotes H2O2
C19 828-861 NP denotes The T cell tyrosine kinase ZAP-70
C20 899-901 NP denotes UV
C21 947-949 NP denotes UV
C22 959-990 NP denotes expression of both CD3 and CD45
C23 1005-1008 NP denotes CD3
C24 1042-1046 NP denotes H2O2
C25 1048-1051 NP denotes UV-
C26 1059-1083 NP denotes activation of NF-kappa B
C27 1143-1170 NP denotes such cell surface molecules
C28 1198-1200 NP denotes UV
C29 1324-1338 NP denotes UV irradiation
C30 1414-1436 NP denotes cell surface receptors
C31 1437-1441 NP denotes that
C32 1494-1498 NP denotes H2O2
R1 C7 C4 coref-ident UV irradiation,UV irradiation
R2 C9 C6 coref-ident protein tyrosine phosphorylation,tyrosine phosphorylation
R3 C10 C8 coref-pron those,protein tyrosine phosphorylation and Ca2+ signals
R4 C12 C3 coref-ident these responses,Several mammalian responses to UV irradiation
R5 C14 C13 coref-relat whose,Normal T lymphocytes
R6 C17 C13 coref-ident all these cell types,Normal T lymphocytes
R7 C19 C1 coref-ident The T cell tyrosine kinase ZAP-70,ZAP-70 tyrosine kinase
R8 C21 C20 coref-ident UV,UV
R9 C22 C16 coref-ident expression of both CD3 and CD45,CD3 or CD45 expression
R10 C23 C15 coref-ident CD3,CD3
R11 C24 C18 coref-ident H2O2,H2O2
R12 C25 C21 coref-ident UV-,UV
R13 C26 C5 coref-ident activation of NF-kappa B,the activation of NF-kappa B
R14 C27 C11 coref-ident such cell surface molecules,cell surface molecules
R15 C28 C25 coref-ident UV,UV-
R16 C29 C7 coref-ident UV irradiation,UV irradiation
R17 C31 C30 coref-relat that,cell surface receptors
R18 C32 C24 coref-ident H2O2,H2O2

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-22 protein_molecule denotes ZAP-70 tyrosine kinase
T2 24-28 protein_molecule denotes CD45
T3 34-49 protein_family_or_group denotes T cell receptor
T4 65-68 other_name denotes UV-
T5 73-78 other_name denotes H2O2-
T6 78-112 other_name denotes induced T cell signal transduction
T7 145-159 other_name denotes UV irradiation
T8 189-199 protein_molecule denotes NF-kappa B
T9 225-233 amino_acid_monomer denotes tyrosine
T10 251-265 other_name denotes UV irradiation
T11 270-274 inorganic denotes H2O2
T12 288-301 cell_type denotes T lymphocytes
T13 317-325 amino_acid_monomer denotes tyrosine
T14 498-511 cell_type denotes T lymphocytes
T15 540-543 protein_molecule denotes CD3
T16 584-592 amino_acid_monomer denotes tyrosine
T17 613-617 atom denotes Ca2+
T18 638-657 cell_line denotes Jurkat T cell lines
T19 671-674 other_name denotes CD3
T20 678-682 other_name denotes CD45
T21 683-693 other_name denotes expression
T22 704-712 other_name denotes impaired
T23 713-715 other_name denotes UV
T24 775-779 atom denotes Ca2+
T25 784-792 amino_acid_monomer denotes tyrosine
T26 822-826 inorganic denotes H2O2
T27 839-847 amino_acid_monomer denotes tyrosine
T28 848-861 protein_molecule denotes kinase ZAP-70
T29 899-901 other_name denotes UV
T30 906-910 inorganic denotes H2O2
T31 922-928 protein_molecule denotes ZAP-70
T32 947-949 other_name denotes UV
T33 978-981 protein_molecule denotes CD3
T34 986-990 protein_molecule denotes CD45
T35 1005-1008 protein_molecule denotes CD3
T36 1042-1046 inorganic denotes H2O2
T37 1048-1050 other_name denotes UV
T38 1073-1083 protein_molecule denotes NF-kappa B
T39 1099-1102 protein_molecule denotes CD3
T40 1148-1170 protein_family_or_group denotes cell surface molecules
T41 1198-1200 other_name denotes UV
T42 1205-1222 cell_type denotes nonlymphoid cells
T43 1228-1260 protein_family_or_group denotes epidermal growth factor receptor
T44 1281-1289 amino_acid_monomer denotes tyrosine
T45 1324-1326 other_name denotes UV
T46 1367-1369 other_name denotes UV
T47 1414-1436 protein_family_or_group denotes cell surface receptors
T48 1462-1484 other_name denotes biological stimulation
T49 1494-1498 inorganic denotes H2O2

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 34-40 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T2 86-92 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T3 288-301 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T4 498-511 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T5 645-651 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T6 832-838 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T7 1228-1244 Body_part denotes epidermal growth http://purl.obolibrary.org/obo/UBERON_0000021