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PubMed:7949138 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 113-118 gene:6886 denotes tal-1
T1 155-190 disease:C1961099 denotes T-cell acute lymphoblastic leukemia
T2 113-118 gene:6886 denotes tal-1
T3 192-197 disease:C1961099 denotes T-ALL
R1 T0 T1 associated_with tal-1,T-cell acute lymphoblastic leukemia
R2 T2 T3 associated_with tal-1,T-ALL

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 9-37 DNA denotes DNase-I hypersensitive sites
T2 58-63 protein denotes TAL-1
T3 81-107 cell_line denotes erythroid and T-cell lines
T4 113-123 DNA denotes tal-1 gene
T5 220-269 cell_type denotes erythroid, megakaryocytic, and mast cell lineages
T6 366-371 DNA denotes tal-1
T7 400-405 DNA denotes tal-1
T8 429-464 cell_line denotes erythroid/megakaryocytic cell lines
T9 472-484 cell_line denotes T-cell lines
T10 508-528 DNA denotes tal-1 rearrangements
T11 581-587 cell_line denotes Jurkat
T12 618-623 DNA denotes tal-1
T13 723-745 DNA denotes tal-15' GC-rich region
T14 761-771 DNA denotes CpG island
T15 791-803 cell_type denotes normal cells
T16 831-865 DNA denotes transcriptionally inactive alleles
T17 869-891 cell_line denotes established cell lines
T18 904-932 DNA denotes DNase-I hypersensitive sites
T19 934-936 DNA denotes HS
T20 957-962 DNA denotes tal-1
T21 970-985 DNA denotes HS I, IV, and V
T22 1019-1054 cell_line denotes erythroid/megakaryocytic cell lines
T23 1068-1073 DNA denotes tal-1
T24 1083-1102 DNA denotes promoters 1a and 1b
T25 1104-1109 DNA denotes HS II
T26 1122-1146 cell_line denotes hematopoietic cell lines
T27 1158-1162 cell_line denotes Hela
T28 1188-1194 cell_line denotes Jurkat
T29 1269-1286 DNA denotes tal-1 promoter 1b
T30 1306-1312 DNA denotes HS III
T31 1325-1328 cell_line denotes HEL
T32 1333-1339 cell_line denotes Jurkat
T33 1365-1370 cell_line denotes DU528
T34 1374-1385 cell_line denotes T-cell line
T35 1397-1407 DNA denotes a t (1;14)
T36 1422-1427 DNA denotes tal-1
T37 1449-1455 DNA denotes exon 4
T38 1493-1512 DNA denotes regulatory elements
T39 1558-1573 DNA denotes tal-1 promoters

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7949138-1#4#9#gene6886 113-118 gene6886 denotes tal-1
7949138-1#46#81#diseaseC1961099 155-190 diseaseC1961099 denotes T-cell acute lymphoblastic leukemia
7949138-1#83#88#diseaseC1961099 192-197 diseaseC1961099 denotes T-ALL
4#9#gene688646#81#diseaseC1961099 7949138-1#4#9#gene6886 7949138-1#46#81#diseaseC1961099 associated_with tal-1,T-cell acute lymphoblastic leukemia
4#9#gene688683#88#diseaseC1961099 7949138-1#4#9#gene6886 7949138-1#83#88#diseaseC1961099 associated_with tal-1,T-ALL

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 58-77 NP denotes TAL-1 transcription
C2 109-123 NP denotes The tal-1 gene
C3 328-352 NP denotes the molecular mechanisms
C4 353-357 NP denotes that
C5 530-549 NP denotes Tal-1 transcription
C6 581-587 NP denotes Jurkat
C8 589-602 NP denotes a T-cell line
C9 603-607 NP denotes that
C10 618-623 NP denotes tal-1
C11 673-682 NP denotes the locus
C7 589-682 NP denotes a T-cell line that expresses tal-1 in the absence of apparent genomic alteration of the locus
C12 719-745 NP denotes the tal-15' GC-rich region
C13 953-968 NP denotes the tal-1 locus
C14 1188-1194 NP denotes Jurkat
C15 1212-1223 NP denotes this region
C16 1290-1304 NP denotes this cell line
C17 1333-1339 NP denotes Jurkat
C18 1365-1370 NP denotes DU528
C20 1372-1385 NP denotes a T-cell line
C21 1386-1390 NP denotes that
C22 1422-1441 NP denotes tal-1 transcription
C19 1372-1455 NP denotes a T-cell line that bears a t (1;14) and initiates tal-1 transcription within exon 4
R1 C4 C3 coref-relat that,the molecular mechanisms
R2 C5 C1 coref-ident Tal-1 transcription,TAL-1 transcription
R3 C9 C8 coref-relat that,a T-cell line
R4 C10 C2 coref-ident tal-1,The tal-1 gene
R5 C7 C6 coref-appos a T-cell line that expresses tal-1 in the absence of apparent genomic alteration of the locus,Jurkat
R6 C13 C11 coref-ident the tal-1 locus,the locus
R7 C14 C6 coref-ident Jurkat,Jurkat
R8 C15 C12 coref-ident this region,the tal-15' GC-rich region
R9 C16 C14 coref-ident this cell line,Jurkat
R10 C17 C14 coref-ident Jurkat,Jurkat
R11 C21 C20 coref-relat that,a T-cell line
R12 C22 C5 coref-ident tal-1 transcription,Tal-1 transcription
R13 C19 C18 coref-appos a T-cell line that bears a t (1;14) and initiates tal-1 transcription within exon 4,DU528

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-108 Sentence denotes Distinct DNase-I hypersensitive sites are associated with TAL-1 transcription in erythroid and T-cell lines.
S2 109-298 Sentence denotes The tal-1 gene, frequently activated in human T-cell acute lymphoblastic leukemia (T-ALL), is expressed in the erythroid, megakaryocytic, and mast cell lineages during normal hematopoiesis.
S3 299-529 Sentence denotes To gain further insight into the molecular mechanisms that control tal-1 expression, we investigated tal-1 chromatin structure in erythroid/megakaryocytic cell lines and in T-cell lines either with or without tal-1 rearrangements.
S4 530-683 Sentence denotes Tal-1 transcription was shown to be monoallelic in Jurkat, a T-cell line that expresses tal-1 in the absence of apparent genomic alteration of the locus.
S5 684-892 Sentence denotes Methylation studies indicated that the tal-15' GC-rich region behaves like a CpG island, hypomethylated in normal cells, and methylated de novo on transcriptionally inactive alleles in established cell lines.
S6 893-969 Sentence denotes Five major DNase-I hypersensitive sites (HS) were mapped in the tal-1 locus.
S7 970-1103 Sentence denotes HS I, IV, and V were exclusively observed in the erythroid/megakaryocytic cell lines that express tal-1 from the promoters 1a and 1b.
S8 1104-1305 Sentence denotes HS II was weak in hematopoietic cell lines, absent in Hela, and greatly enhanced in Jurkat, suggesting that this region might be implicated in the cis-activation of tal-1 promoter 1b in this cell line.
S9 1306-1456 Sentence denotes HS III was weak in HEL and Jurkat, and greatly enhanced in DU528, a T-cell line that bears a t (1;14) and initiates tal-1 transcription within exon 4.
S10 1457-1574 Sentence denotes These results suggest that distinct regulatory elements are associated with the use of the different tal-1 promoters.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 9-37 DNA_domain_or_region denotes DNase-I hypersensitive sites
T2 58-63 protein_molecule denotes TAL-1
T3 113-123 DNA_domain_or_region denotes tal-1 gene
T4 149-190 other_name denotes human T-cell acute lymphoblastic leukemia
T5 192-197 other_name denotes T-ALL
T6 277-297 other_name denotes normal hematopoiesis
T7 366-371 DNA_domain_or_region denotes tal-1
T8 400-405 DNA_domain_or_region denotes tal-1
T9 429-464 cell_line denotes erythroid/megakaryocytic cell lines
T10 472-484 cell_line denotes T-cell lines
T11 508-513 DNA_domain_or_region denotes tal-1
T12 581-587 cell_line denotes Jurkat
T13 618-623 DNA_domain_or_region denotes tal-1
T14 684-703 other_name denotes Methylation studies
T15 723-745 DNA_domain_or_region denotes tal-15' GC-rich region
T16 761-771 DNA_domain_or_region denotes CpG island
T17 791-803 cell_type denotes normal cells
T18 831-865 DNA_domain_or_region denotes transcriptionally inactive alleles
T19 869-891 cell_line denotes established cell lines
T20 904-932 DNA_domain_or_region denotes DNase-I hypersensitive sites
T21 934-936 DNA_domain_or_region denotes HS
T22 957-962 DNA_domain_or_region denotes tal-1
T23 1019-1054 cell_line denotes erythroid/megakaryocytic cell lines
T24 1068-1073 DNA_domain_or_region denotes tal-1
T25 1104-1109 DNA_domain_or_region denotes HS II
T26 1122-1146 cell_line denotes hematopoietic cell lines
T27 1158-1162 cell_line denotes Hela
T28 1188-1194 cell_line denotes Jurkat
T29 1269-1274 DNA_domain_or_region denotes tal-1
T30 1306-1312 DNA_domain_or_region denotes HS III
T31 1325-1328 cell_line denotes HEL
T32 1333-1339 cell_line denotes Jurkat
T33 1365-1370 cell_line denotes DU528
T34 1374-1385 cell_line denotes T-cell line
T35 1397-1407 DNA_domain_or_region denotes a t (1;14)
T36 1422-1427 DNA_domain_or_region denotes tal-1
T37 1449-1455 DNA_domain_or_region denotes exon 4
T38 1493-1512 DNA_domain_or_region denotes regulatory elements
T39 1558-1563 DNA_domain_or_region denotes tal-1