PubMed:7918086 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	134-143	cell_type	denotes	basophils
T2	285-296	DNA	denotes	genomic DNA
T3	334-355	cell_type	denotes	peripheral leucocytes
T4	396-405	cell_type	denotes	basophils
T5	411-420	protein	denotes	RAR alpha
T6	473-490	protein	denotes	chimaeric product
T7	494-507	protein	denotes	PML-RAR alpha
T8	691-700	cell_type	denotes	basophils
T9	779-794	cell_line	denotes	leukaemic clone

Id	Subject	Object	Predicate	Lexical cue
C1	0-17	NP	denotes	Marked basophilia
C2	21-50	NP	denotes	acute promyelocytic leukaemia
C3	130-143	NP	denotes	the basophils
C5	170-199	NP	denotes	acute promyelocytic leukaemia
C4	155-199	NP	denotes	a patient with acute promyelocytic leukaemia
C6	200-203	NP	denotes	who
C7	214-231	NP	denotes	marked basophilia
C8	320-331	NP	denotes	the patient
C9	392-405	NP	denotes	the basophils
C10	407-536	NP	denotes	The RAR alpha rearranged band in the Southern blot analysis and a chimaeric product of PML-RAR alpha by polymerase chain reaction
C11	566-580	NP	denotes	ATRA treatment
C12	620-632	NP	denotes	both of them
C13	687-700	NP	denotes	the basophils
C14	701-706	NP	denotes	which
C15	723-741	NP	denotes	the ATRA treatment
R1	C5	C2	coref-ident	acute promyelocytic leukaemia,acute promyelocytic leukaemia
R2	C6	C4	coref-relat	who,a patient with acute promyelocytic leukaemia
R3	C7	C1	coref-ident	marked basophilia,Marked basophilia
R4	C8	C4	coref-ident	the patient,a patient with acute promyelocytic leukaemia
R5	C9	C3	coref-ident	the basophils,the basophils
R6	C12	C10	coref-ident	both of them,The RAR alpha rearranged band in the Southern blot analysis and a chimaeric product of PML-RAR alpha by polymerase chain reaction
R7	C13	C9	coref-ident	the basophils,the basophils
R8	C14	C13	coref-relat	which,the basophils
R9	C15	C11	coref-ident	the ATRA treatment,ATRA treatment

Id	Subject	Object	Predicate	Lexical cue
S1	0-144	Sentence	denotes	Marked basophilia in acute promyelocytic leukaemia treated with all-trans retinoic acid: molecular analysis of the cell origin of the basophils.
S2	145-273	Sentence	denotes	We report a patient with acute promyelocytic leukaemia who developed marked basophilia during all-trans retinoic acid treatment.
S3	274-406	Sentence	denotes	We studied genomic DNA and RNA extracted from the patient's peripheral leucocytes in order to determine the origin of the basophils.
S4	407-658	Sentence	denotes	The RAR alpha rearranged band in the Southern blot analysis and a chimaeric product of PML-RAR alpha by polymerase chain reaction were strongly visible before ATRA treatment, but at the time of maximal basophilia both of them were markedly diminished.
S5	659-795	Sentence	denotes	These findings suggest that the basophils which appeared during the ATRA treatment are reactive in nature rather than a leukaemic clone.

Id	Subject	Object	Predicate	Lexical cue
T1	0-17	other_name	denotes	Marked basophilia
T2	21-50	other_name	denotes	acute promyelocytic leukaemia
T3	64-87	other_organic_compound	denotes	all-trans retinoic acid
T4	134-143	cell_type	denotes	basophils
T5	157-164	multi_cell	denotes	patient
T6	170-199	other_name	denotes	acute promyelocytic leukaemia
T7	239-262	other_organic_compound	denotes	all-trans retinoic acid
T8	285-296	DNA_family_or_group	denotes	genomic DNA
T9	334-355	cell_type	denotes	peripheral leucocytes
T10	396-405	cell_type	denotes	basophils
T11	411-420	protein_molecule	denotes	RAR alpha
T12	444-466	other_name	denotes	Southern blot analysis
T13	473-490	protein_family_or_group	denotes	chimaeric product
T14	494-507	protein_molecule	denotes	PML-RAR alpha
T15	511-536	other_name	denotes	polymerase chain reaction
T16	566-580	other_name	denotes	ATRA treatment
T17	601-619	other_name	denotes	maximal basophilia
T18	691-700	cell_type	denotes	basophils
T19	727-741	other_name	denotes	ATRA treatment
T20	779-794	cell_line	denotes	leukaemic clone