PubMed:7901202
Annnotations
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 285-292 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T2 | 285-292 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T3 | 285-292 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T4 | 285-292 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T5 | 285-292 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T6 | 285-292 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T7 | 953-960 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T8 | 953-960 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T9 | 953-960 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T10 | 953-960 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T11 | 953-960 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T12 | 953-960 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T13 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T14 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T15 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T16 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T17 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T18 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 278-292 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T2 | 285-292 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T4 | 772-781 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T6 | 946-960 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T7 | 953-960 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T9 | 1570-1584 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T10 | 1577-1584 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 285-292 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T2 | 285-292 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T3 | 285-292 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T4 | 285-292 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T5 | 285-292 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T6 | 285-292 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T7 | 953-960 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T8 | 953-960 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T9 | 953-960 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T10 | 953-960 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T11 | 953-960 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T12 | 953-960 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T13 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T14 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T15 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T16 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T17 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T18 | 1577-1584 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. |
| T2 | 119-357 | Sentence | denotes | This report describes the isolation of a cDNA encoding a novel human Gal beta (1-3/1-4)GlcNac alpha 2,3-sialyl-transferase involved in the biosynthesis of the sialyl Lewis x determinant (NeuAc alpha 2-3 Gal beta 1-4(Fuc alpha 1-3)GlcNAc). |
| T3 | 358-475 | Sentence | denotes | A cDNA library of the human melanoma cell line WM266-4 was constructed in an Epstein-Barr virus-based cloning vector. |
| T4 | 476-726 | Sentence | denotes | Selection of the B-cell line Namalwa expressing transfected cDNAs in the presence of the cytotoxic lectin Ricinus communis agglutinin 120 gave a cDNA encoding a protein with type II transmembrane topology, as found for mammalian glycosyltransferases. |
| T5 | 727-1049 | Sentence | denotes | The use of this lectin, which is specific to galactose residues (especially the Gal beta 1-4GlcNAc structure), originates from our prediction that the modification of the Gal beta 1-4GlcNAc structure (a backbone of the sialyl Lewis x structure) by glycosyltransferases may increase the levels of resistance to this lectin. |
| T6 | 1050-1193 | Sentence | denotes | Comparison of this cDNA sequence with those of three other cloned sialyltransferases revealed two conserved regions shared by all four enzymes. |
| T7 | 1194-1492 | Sentence | denotes | Expression of the COOH-terminal catalytic domain of this protein showed alpha 2,3-sialyltransferase activity with substrate specificity different from that of CMP-N-acetylneuraminate:N-acetyllactosaminide alpha-2,3-sialyltransferase (Gal-beta 1-3(4)GlcNAc alpha 2,3-sialyltransferase, EC 2.4.99.6). |
| T8 | 1493-1594 | Sentence | denotes | Furthermore, expression of this cDNA in Namalwa cells increased the level of sialyl Lewis x antigens. |
| T9 | 1595-1730 | Sentence | denotes | The cloning approach based on lectin resistance may be useful for the isolation of cDNAs encoding other mammalian glycosyltransferases. |
| T1 | 0-118 | Sentence | denotes | Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. |
| T2 | 119-357 | Sentence | denotes | This report describes the isolation of a cDNA encoding a novel human Gal beta (1-3/1-4)GlcNac alpha 2,3-sialyl-transferase involved in the biosynthesis of the sialyl Lewis x determinant (NeuAc alpha 2-3 Gal beta 1-4(Fuc alpha 1-3)GlcNAc). |
| T3 | 358-475 | Sentence | denotes | A cDNA library of the human melanoma cell line WM266-4 was constructed in an Epstein-Barr virus-based cloning vector. |
| T4 | 476-726 | Sentence | denotes | Selection of the B-cell line Namalwa expressing transfected cDNAs in the presence of the cytotoxic lectin Ricinus communis agglutinin 120 gave a cDNA encoding a protein with type II transmembrane topology, as found for mammalian glycosyltransferases. |
| T5 | 727-1049 | Sentence | denotes | The use of this lectin, which is specific to galactose residues (especially the Gal beta 1-4GlcNAc structure), originates from our prediction that the modification of the Gal beta 1-4GlcNAc structure (a backbone of the sialyl Lewis x structure) by glycosyltransferases may increase the levels of resistance to this lectin. |
| T6 | 1050-1193 | Sentence | denotes | Comparison of this cDNA sequence with those of three other cloned sialyltransferases revealed two conserved regions shared by all four enzymes. |
| T7 | 1194-1492 | Sentence | denotes | Expression of the COOH-terminal catalytic domain of this protein showed alpha 2,3-sialyltransferase activity with substrate specificity different from that of CMP-N-acetylneuraminate:N-acetyllactosaminide alpha-2,3-sialyltransferase (Gal-beta 1-3(4)GlcNAc alpha 2,3-sialyltransferase, EC 2.4.99.6). |
| T8 | 1493-1594 | Sentence | denotes | Furthermore, expression of this cDNA in Namalwa cells increased the level of sialyl Lewis x antigens. |
| T9 | 1595-1730 | Sentence | denotes | The cloning approach based on lectin resistance may be useful for the isolation of cDNAs encoding other mammalian glycosyltransferases. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 278-292 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T2 | 285-292 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T3 | 285-292 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T4 | 772-781 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T5 | 772-781 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T6 | 946-960 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T7 | 953-960 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T8 | 953-960 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T9 | 1570-1584 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T10 | 1577-1584 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T11 | 1577-1584 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 278-292 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T2 | 285-292 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T3 | 946-960 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T4 | 953-960 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T5 | 1570-1584 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T6 | 1577-1584 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 655-657 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 49-55 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T2 | 206-212 | chem:24139 | denotes | GlcNac |
| PD-NGLY1-deficiency-B_T3 | 349-355 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T4 | 1443-1449 | chem:24139 | denotes | GlcNAc |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 386-394 | Disease | denotes | melanoma | http://purl.obolibrary.org/obo/MONDO_0005105 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 386-394 | Phenotype | denotes | melanoma | HP:0002861 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 278-292 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T2 | 306-311 | Glycan | denotes | NeuAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
| T3 | 946-960 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T4 | 1570-1584 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 386-394 | Phenotype | denotes | melanoma | HP:0002861 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 386-394 | Disease | denotes | melanoma | http://purl.obolibrary.org/obo/MONDO_0005105 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 182-187 | OrganismTaxon | denotes | human | 9606 |
| T2 | 380-385 | OrganismTaxon | denotes | human | 9606 |
| T3 | 435-453 | OrganismTaxon | denotes | Epstein-Barr virus | 10376 |
| T4 | 582-598 | OrganismTaxon | denotes | Ricinus communis | 3988 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 493-499 | Cell | denotes | B-cell | http://purl.obolibrary.org/obo/CL:0000236 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 493-499 | Body_part | denotes | B-cell | http://purl.obolibrary.org/obo/CL_0000236 |
| T2 | 658-671 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
| T3 | 930-938 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. |
| T2 | 119-357 | Sentence | denotes | This report describes the isolation of a cDNA encoding a novel human Gal beta (1-3/1-4)GlcNac alpha 2,3-sialyl-transferase involved in the biosynthesis of the sialyl Lewis x determinant (NeuAc alpha 2-3 Gal beta 1-4(Fuc alpha 1-3)GlcNAc). |
| T3 | 358-475 | Sentence | denotes | A cDNA library of the human melanoma cell line WM266-4 was constructed in an Epstein-Barr virus-based cloning vector. |
| T4 | 476-726 | Sentence | denotes | Selection of the B-cell line Namalwa expressing transfected cDNAs in the presence of the cytotoxic lectin Ricinus communis agglutinin 120 gave a cDNA encoding a protein with type II transmembrane topology, as found for mammalian glycosyltransferases. |
| T5 | 727-1049 | Sentence | denotes | The use of this lectin, which is specific to galactose residues (especially the Gal beta 1-4GlcNAc structure), originates from our prediction that the modification of the Gal beta 1-4GlcNAc structure (a backbone of the sialyl Lewis x structure) by glycosyltransferases may increase the levels of resistance to this lectin. |
| T6 | 1050-1193 | Sentence | denotes | Comparison of this cDNA sequence with those of three other cloned sialyltransferases revealed two conserved regions shared by all four enzymes. |
| T7 | 1194-1492 | Sentence | denotes | Expression of the COOH-terminal catalytic domain of this protein showed alpha 2,3-sialyltransferase activity with substrate specificity different from that of CMP-N-acetylneuraminate:N-acetyllactosaminide alpha-2,3-sialyltransferase (Gal-beta 1-3(4)GlcNAc alpha 2,3-sialyltransferase, EC 2.4.99.6). |
| T8 | 1493-1594 | Sentence | denotes | Furthermore, expression of this cDNA in Namalwa cells increased the level of sialyl Lewis x antigens. |
| T9 | 1595-1730 | Sentence | denotes | The cloning approach based on lectin resistance may be useful for the isolation of cDNAs encoding other mammalian glycosyltransferases. |
| T1 | 0-118 | Sentence | denotes | Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. |
| T2 | 119-357 | Sentence | denotes | This report describes the isolation of a cDNA encoding a novel human Gal beta (1-3/1-4)GlcNac alpha 2,3-sialyl-transferase involved in the biosynthesis of the sialyl Lewis x determinant (NeuAc alpha 2-3 Gal beta 1-4(Fuc alpha 1-3)GlcNAc). |
| T3 | 358-475 | Sentence | denotes | A cDNA library of the human melanoma cell line WM266-4 was constructed in an Epstein-Barr virus-based cloning vector. |
| T4 | 476-726 | Sentence | denotes | Selection of the B-cell line Namalwa expressing transfected cDNAs in the presence of the cytotoxic lectin Ricinus communis agglutinin 120 gave a cDNA encoding a protein with type II transmembrane topology, as found for mammalian glycosyltransferases. |
| T5 | 727-1049 | Sentence | denotes | The use of this lectin, which is specific to galactose residues (especially the Gal beta 1-4GlcNAc structure), originates from our prediction that the modification of the Gal beta 1-4GlcNAc structure (a backbone of the sialyl Lewis x structure) by glycosyltransferases may increase the levels of resistance to this lectin. |
| T6 | 1050-1193 | Sentence | denotes | Comparison of this cDNA sequence with those of three other cloned sialyltransferases revealed two conserved regions shared by all four enzymes. |
| T7 | 1194-1492 | Sentence | denotes | Expression of the COOH-terminal catalytic domain of this protein showed alpha 2,3-sialyltransferase activity with substrate specificity different from that of CMP-N-acetylneuraminate:N-acetyllactosaminide alpha-2,3-sialyltransferase (Gal-beta 1-3(4)GlcNAc alpha 2,3-sialyltransferase, EC 2.4.99.6). |
| T8 | 1493-1594 | Sentence | denotes | Furthermore, expression of this cDNA in Namalwa cells increased the level of sialyl Lewis x antigens. |
| T9 | 1595-1730 | Sentence | denotes | The cloning approach based on lectin resistance may be useful for the isolation of cDNAs encoding other mammalian glycosyltransferases. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. |
| T2 | 119-357 | Sentence | denotes | This report describes the isolation of a cDNA encoding a novel human Gal beta (1-3/1-4)GlcNac alpha 2,3-sialyl-transferase involved in the biosynthesis of the sialyl Lewis x determinant (NeuAc alpha 2-3 Gal beta 1-4(Fuc alpha 1-3)GlcNAc). |
| T3 | 358-475 | Sentence | denotes | A cDNA library of the human melanoma cell line WM266-4 was constructed in an Epstein-Barr virus-based cloning vector. |
| T4 | 476-726 | Sentence | denotes | Selection of the B-cell line Namalwa expressing transfected cDNAs in the presence of the cytotoxic lectin Ricinus communis agglutinin 120 gave a cDNA encoding a protein with type II transmembrane topology, as found for mammalian glycosyltransferases. |
| T5 | 727-1049 | Sentence | denotes | The use of this lectin, which is specific to galactose residues (especially the Gal beta 1-4GlcNAc structure), originates from our prediction that the modification of the Gal beta 1-4GlcNAc structure (a backbone of the sialyl Lewis x structure) by glycosyltransferases may increase the levels of resistance to this lectin. |
| T6 | 1050-1193 | Sentence | denotes | Comparison of this cDNA sequence with those of three other cloned sialyltransferases revealed two conserved regions shared by all four enzymes. |
| T7 | 1194-1492 | Sentence | denotes | Expression of the COOH-terminal catalytic domain of this protein showed alpha 2,3-sialyltransferase activity with substrate specificity different from that of CMP-N-acetylneuraminate:N-acetyllactosaminide alpha-2,3-sialyltransferase (Gal-beta 1-3(4)GlcNAc alpha 2,3-sialyltransferase, EC 2.4.99.6). |
| T8 | 1493-1594 | Sentence | denotes | Furthermore, expression of this cDNA in Namalwa cells increased the level of sialyl Lewis x antigens. |
| T9 | 1595-1730 | Sentence | denotes | The cloning approach based on lectin resistance may be useful for the isolation of cDNAs encoding other mammalian glycosyltransferases. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 278-292 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T2 | 306-311 | Glycan | denotes | NeuAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
| T3 | 946-960 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T4 | 1570-1584 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 278-292 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T2 | 946-960 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T3 | 1570-1584 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
Lectin-Jamboree-Sentence
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. |
| T2 | 119-357 | Sentence | denotes | This report describes the isolation of a cDNA encoding a novel human Gal beta (1-3/1-4)GlcNac alpha 2,3-sialyl-transferase involved in the biosynthesis of the sialyl Lewis x determinant (NeuAc alpha 2-3 Gal beta 1-4(Fuc alpha 1-3)GlcNAc). |
| T3 | 358-475 | Sentence | denotes | A cDNA library of the human melanoma cell line WM266-4 was constructed in an Epstein-Barr virus-based cloning vector. |
| T4 | 476-726 | Sentence | denotes | Selection of the B-cell line Namalwa expressing transfected cDNAs in the presence of the cytotoxic lectin Ricinus communis agglutinin 120 gave a cDNA encoding a protein with type II transmembrane topology, as found for mammalian glycosyltransferases. |
| T5 | 727-1049 | Sentence | denotes | The use of this lectin, which is specific to galactose residues (especially the Gal beta 1-4GlcNAc structure), originates from our prediction that the modification of the Gal beta 1-4GlcNAc structure (a backbone of the sialyl Lewis x structure) by glycosyltransferases may increase the levels of resistance to this lectin. |
| T6 | 1050-1193 | Sentence | denotes | Comparison of this cDNA sequence with those of three other cloned sialyltransferases revealed two conserved regions shared by all four enzymes. |
| T7 | 1194-1492 | Sentence | denotes | Expression of the COOH-terminal catalytic domain of this protein showed alpha 2,3-sialyltransferase activity with substrate specificity different from that of CMP-N-acetylneuraminate:N-acetyllactosaminide alpha-2,3-sialyltransferase (Gal-beta 1-3(4)GlcNAc alpha 2,3-sialyltransferase, EC 2.4.99.6). |
| T8 | 1493-1594 | Sentence | denotes | Furthermore, expression of this cDNA in Namalwa cells increased the level of sialyl Lewis x antigens. |
| T9 | 1595-1730 | Sentence | denotes | The cloning approach based on lectin resistance may be useful for the isolation of cDNAs encoding other mammalian glycosyltransferases. |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 182-187 | OrganismTaxon | denotes | human | 9606 |
| T2 | 380-385 | OrganismTaxon | denotes | human | 9606 |
| T3 | 435-453 | OrganismTaxon | denotes | Epstein-Barr virus | 10376 |
| T4 | 582-598 | OrganismTaxon | denotes | Ricinus communis | 3988 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 278-292 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T2 | 946-960 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T3 | 1570-1584 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 493-499 | Body_part | denotes | B-cell | http://purl.obolibrary.org/obo/CL_0000236 |
| T2 | 658-671 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
| T3 | 930-938 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 493-499 | Cell | denotes | B-cell | http://purl.obolibrary.org/obo/CL:0000236 |