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PubMed:7892884 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 197-202 gene:672 denotes BRCA1
T1 211-218 disease:C0006826 denotes cancers
T2 197-202 gene:672 denotes BRCA1
T3 253-267 disease:C0029925 denotes ovarian cancer
T4 197-202 gene:672 denotes BRCA1
T5 253-267 disease:C1140680 denotes ovarian cancer
R1 T0 T1 associated_with BRCA1,cancers
R2 T2 T3 associated_with BRCA1,ovarian cancer
R3 T4 T5 associated_with BRCA1,ovarian cancer

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2832 1428-1433 gene:672 denotes BRCA1
T2833 1325-1339 disease:C0029925 denotes ovarian cancer
R1 T2832 T2833 associated_with BRCA1,ovarian cancer
R2 T2832 T2833 associated_with BRCA1,ovarian cancer

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-106 Sentence denotes Loss of heterozygosity on chromosome 17q11-21 in cancers of women who have both breast and ovarian cancer.
TextSentencer_T2 107-117 Sentence denotes OBJECTIVE:
TextSentencer_T3 118-268 Sentence denotes Our purpose was to determine the frequency of allele loss in the region of the BRCA1 gene in cancers of women who have both breast and ovarian cancer.
TextSentencer_T4 269-282 Sentence denotes STUDY DESIGN:
TextSentencer_T5 283-544 Sentence denotes Four polymorphic microsatellite markers on chromosome 17q11-21 were examined by the polymerase chain reaction in deoxyribonucleic acid from paraffin blocks of normal tissues, breast cancers, and ovarian cancers in 24 women who had primary cancers in both sites.
TextSentencer_T6 545-553 Sentence denotes RESULTS:
TextSentencer_T7 554-684 Sentence denotes Loss of heterozygosity was seen in one or more markers on chromosome 17q11-21 in 46% of breast cancers and 78% of ovarian cancers.
TextSentencer_T8 685-803 Sentence denotes In 38% of cases allele loss was seen in both cancers, and in all these cases the same allele was lost in both cancers.
TextSentencer_T9 804-1023 Sentence denotes Significantly younger ages at diagnosis of both breast and ovarian cancer were noted among cases with allele loss in both cancers compared with cases in which allele loss was found only in the ovarian cancer (p < 0.05).
TextSentencer_T10 1024-1036 Sentence denotes CONCLUSIONS:
TextSentencer_T11 1037-1250 Sentence denotes Because cases in which 17q11-21 allele loss was seen in both cancers had a young age of onset and the same allele was always deleted in both cancers, hereditary alterations in BRCA1 may play a role in this subset.
TextSentencer_T12 1251-1434 Sentence denotes The older age of onset in cases in which allele loss was seen only in the ovarian cancer suggests that the development of these cancers is not related to an inherited defect in BRCA1.
T1 0-106 Sentence denotes Loss of heterozygosity on chromosome 17q11-21 in cancers of women who have both breast and ovarian cancer.
T2 107-117 Sentence denotes OBJECTIVE:
T3 118-268 Sentence denotes Our purpose was to determine the frequency of allele loss in the region of the BRCA1 gene in cancers of women who have both breast and ovarian cancer.
T4 269-282 Sentence denotes STUDY DESIGN:
T5 283-544 Sentence denotes Four polymorphic microsatellite markers on chromosome 17q11-21 were examined by the polymerase chain reaction in deoxyribonucleic acid from paraffin blocks of normal tissues, breast cancers, and ovarian cancers in 24 women who had primary cancers in both sites.
T6 545-553 Sentence denotes RESULTS:
T7 554-684 Sentence denotes Loss of heterozygosity was seen in one or more markers on chromosome 17q11-21 in 46% of breast cancers and 78% of ovarian cancers.
T8 685-803 Sentence denotes In 38% of cases allele loss was seen in both cancers, and in all these cases the same allele was lost in both cancers.
T9 804-1023 Sentence denotes Significantly younger ages at diagnosis of both breast and ovarian cancer were noted among cases with allele loss in both cancers compared with cases in which allele loss was found only in the ovarian cancer (p < 0.05).
T10 1024-1036 Sentence denotes CONCLUSIONS:
T11 1037-1250 Sentence denotes Because cases in which 17q11-21 allele loss was seen in both cancers had a young age of onset and the same allele was always deleted in both cancers, hereditary alterations in BRCA1 may play a role in this subset.
T12 1251-1434 Sentence denotes The older age of onset in cases in which allele loss was seen only in the ovarian cancer suggests that the development of these cancers is not related to an inherited defect in BRCA1.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 80-86 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T2 242-248 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T3 458-464 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T4 642-648 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T5 852-858 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T6 449-456 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 449-456 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 80-86 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T3 242-248 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T4 458-464 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T5 642-648 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T6 852-858 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast