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PubMed:7890658 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-143 Sentence denotes Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter.
T2 144-391 Sentence denotes A DNA response element (TR2RE-SV40) for the TR2 orphan receptor, a member of the steroid-thyroid hormone receptor superfamily, has been identified in the simian virus 40 (SV40) +55 region (nucleotide numbers 368-389, 5'-GTTAAGGTTCGTAGGTCATGGA-3').
T3 392-615 Sentence denotes Electrophoretic mobility shift assay, using in vitro translated TR2 orphan receptor with a molecular mass of 67 kilodaltons, showed a specific binding with high affinity (dissociation constant = 9 nM) for this DNA sequence.
T4 616-993 Sentence denotes DNA-swap experiments using chloramphenicol acetyl-transferase assay demonstrated that androgen can suppress the transcriptional activities of SV40 early promoter via the interaction between this TR2RE-SV40 and the chimeric receptor AR/TR2/AR with the DNA-binding domain of the TR2 orphan receptor flanked by the N-terminal and androgen-binding domains of the androgen receptor.
T5 994-1132 Sentence denotes In addition, this TR2RE-SV40 can function as a repressor to suppress the transcriptional activities of both SV40 early and late promoters.
T6 1133-1331 Sentence denotes Together, these data suggest the TR2RE-SV40 may represent the first identified natural DNA response element for the TR2 orphan receptor that may function as a repressor for the SV40 gene expression.
T1 0-143 Sentence denotes Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter.
T2 144-391 Sentence denotes A DNA response element (TR2RE-SV40) for the TR2 orphan receptor, a member of the steroid-thyroid hormone receptor superfamily, has been identified in the simian virus 40 (SV40) +55 region (nucleotide numbers 368-389, 5'-GTTAAGGTTCGTAGGTCATGGA-3').
T3 392-615 Sentence denotes Electrophoretic mobility shift assay, using in vitro translated TR2 orphan receptor with a molecular mass of 67 kilodaltons, showed a specific binding with high affinity (dissociation constant = 9 nM) for this DNA sequence.
T4 616-993 Sentence denotes DNA-swap experiments using chloramphenicol acetyl-transferase assay demonstrated that androgen can suppress the transcriptional activities of SV40 early promoter via the interaction between this TR2RE-SV40 and the chimeric receptor AR/TR2/AR with the DNA-binding domain of the TR2 orphan receptor flanked by the N-terminal and androgen-binding domains of the androgen receptor.
T5 994-1132 Sentence denotes In addition, this TR2RE-SV40 can function as a repressor to suppress the transcriptional activities of both SV40 early and late promoters.
T6 1133-1331 Sentence denotes Together, these data suggest the TR2RE-SV40 may represent the first identified natural DNA response element for the TR2 orphan receptor that may function as a repressor for the SV40 gene expression.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 233-240 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 18-60 DNA denotes human TR2 orphan receptor response element
T2 68-99 DNA denotes transcriptional initiation site
T3 107-142 DNA denotes simian virus 40 major late promoter
T4 146-166 DNA denotes DNA response element
T5 168-178 DNA denotes TR2RE-SV40
T6 188-207 protein denotes TR2 orphan receptor
T7 225-269 protein denotes steroid-thyroid hormone receptor superfamily
T8 298-331 DNA denotes simian virus 40 (SV40) +55 region
T9 333-359 DNA denotes nucleotide numbers 368-389
T10 456-475 protein denotes TR2 orphan receptor
T11 501-515 protein denotes 67 kilodaltons
T12 643-677 protein denotes chloramphenicol acetyl-transferase
T13 758-777 DNA denotes SV40 early promoter
T14 811-821 DNA denotes TR2RE-SV40
T15 830-857 protein denotes chimeric receptor AR/TR2/AR
T16 867-885 protein denotes DNA-binding domain
T17 893-912 protein denotes TR2 orphan receptor
T18 928-967 protein denotes N-terminal and androgen-binding domains
T19 975-992 protein denotes androgen receptor
T20 1012-1022 DNA denotes TR2RE-SV40
T21 1102-1131 DNA denotes SV40 early and late promoters
T22 1166-1176 DNA denotes TR2RE-SV40
T23 1220-1240 DNA denotes DNA response element
T24 1249-1268 protein denotes TR2 orphan receptor

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 18-60 NP denotes human TR2 orphan receptor response element
C3 184-207 NP denotes the TR2 orphan receptor
C2 144-207 NP denotes A DNA response element (TR2RE-SV40) for the TR2 orphan receptor
C4 209-269 NP denotes a member of the steroid-thyroid hormone receptor superfamily
C5 806-821 NP denotes this TR2RE-SV40
C6 889-912 NP denotes the TR2 orphan receptor
C7 1007-1022 NP denotes this TR2RE-SV40
C8 1162-1176 NP denotes the TR2RE-SV40
C10 1245-1268 NP denotes the TR2 orphan receptor
C9 1191-1268 NP denotes the first identified natural DNA response element for the TR2 orphan receptor
C11 1269-1273 NP denotes that
R1 C2 C1 coref-ident A DNA response element (TR2RE-SV40) for the TR2 orphan receptor,human TR2 orphan receptor response element
R2 C4 C3 coref-appos a member of the steroid-thyroid hormone receptor superfamily,the TR2 orphan receptor
R3 C5 C2 coref-ident this TR2RE-SV40,A DNA response element (TR2RE-SV40) for the TR2 orphan receptor
R4 C6 C3 coref-ident the TR2 orphan receptor,the TR2 orphan receptor
R5 C7 C5 coref-ident this TR2RE-SV40,this TR2RE-SV40
R6 C8 C7 coref-ident the TR2RE-SV40,this TR2RE-SV40
R7 C10 C6 coref-ident the TR2 orphan receptor,the TR2 orphan receptor
R8 C9 C2 coref-ident the first identified natural DNA response element for the TR2 orphan receptor,A DNA response element (TR2RE-SV40) for the TR2 orphan receptor
R9 C11 C9 coref-relat that,the first identified natural DNA response element for the TR2 orphan receptor

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-143 Sentence denotes Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter.
S2 144-391 Sentence denotes A DNA response element (TR2RE-SV40) for the TR2 orphan receptor, a member of the steroid-thyroid hormone receptor superfamily, has been identified in the simian virus 40 (SV40) +55 region (nucleotide numbers 368-389, 5'-GTTAAGGTTCGTAGGTCATGGA-3').
S3 392-615 Sentence denotes Electrophoretic mobility shift assay, using in vitro translated TR2 orphan receptor with a molecular mass of 67 kilodaltons, showed a specific binding with high affinity (dissociation constant = 9 nM) for this DNA sequence.
S4 616-993 Sentence denotes DNA-swap experiments using chloramphenicol acetyl-transferase assay demonstrated that androgen can suppress the transcriptional activities of SV40 early promoter via the interaction between this TR2RE-SV40 and the chimeric receptor AR/TR2/AR with the DNA-binding domain of the TR2 orphan receptor flanked by the N-terminal and androgen-binding domains of the androgen receptor.
S5 994-1132 Sentence denotes In addition, this TR2RE-SV40 can function as a repressor to suppress the transcriptional activities of both SV40 early and late promoters.
S6 1133-1331 Sentence denotes Together, these data suggest the TR2RE-SV40 may represent the first identified natural DNA response element for the TR2 orphan receptor that may function as a repressor for the SV40 gene expression.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 18-43 protein_molecule denotes human TR2 orphan receptor
T2 68-99 DNA_domain_or_region denotes transcriptional initiation site
T3 107-122 virus denotes simian virus 40
T4 146-166 DNA_domain_or_region denotes DNA response element
T5 168-178 DNA_domain_or_region denotes TR2RE-SV40
T6 188-207 protein_molecule denotes TR2 orphan receptor
T7 225-269 protein_family_or_group denotes steroid-thyroid hormone receptor superfamily
T8 298-313 virus denotes simian virus 40
T9 315-319 virus denotes SV40
T10 333-359 DNA_domain_or_region denotes nucleotide numbers 368-389
T11 361-389 polynucleotide denotes 5'-GTTAAGGTTCGTAGGTCATGGA-3'
T12 392-428 other_name denotes Electrophoretic mobility shift assay
T13 456-475 protein_molecule denotes TR2 orphan receptor
T14 501-515 protein_molecule denotes 67 kilodaltons
T15 616-636 other_name denotes DNA-swap experiments
T16 643-677 protein_molecule denotes chloramphenicol acetyl-transferase
T17 702-710 lipid denotes androgen
T18 728-754 other_name denotes transcriptional activities
T19 758-762 virus denotes SV40
T20 811-817 protein_domain_or_region denotes TR2RE-
T21 817-821 virus denotes SV40
T22 830-857 protein_molecule denotes chimeric receptor AR/TR2/AR
T23 867-885 protein_domain_or_region denotes DNA-binding domain
T24 893-912 protein_molecule denotes TR2 orphan receptor
T25 975-992 protein_molecule denotes androgen receptor
T26 1012-1018 DNA_domain_or_region denotes TR2RE-
T27 1018-1022 virus denotes SV40
T28 1067-1093 other_name denotes transcriptional activities
T29 1166-1172 DNA_domain_or_region denotes TR2RE-
T30 1172-1176 virus denotes SV40
T31 1220-1240 DNA_domain_or_region denotes DNA response element
T32 1249-1268 protein_molecule denotes TR2 orphan receptor
T33 1310-1314 virus denotes SV40

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 18-23 OrganismTaxon denotes human 9606
T2 107-122 OrganismTaxon denotes simian virus 40 1891767
T3 174-178 OrganismTaxon denotes SV40 1891767
T4 298-313 OrganismTaxon denotes simian virus 40 1891767
T5 315-319 OrganismTaxon denotes SV40 1891767
T6 758-762 OrganismTaxon denotes SV40 1891767
T7 817-821 OrganismTaxon denotes SV40 1891767
T8 1018-1022 OrganismTaxon denotes SV40 1891767
T9 1102-1106 OrganismTaxon denotes SV40 1891767
T10 1172-1176 OrganismTaxon denotes SV40 1891767
T11 1310-1314 OrganismTaxon denotes SV40 1891767

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 233-240 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 233-240 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046