PubMed:7849291
Annnotations
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-86 | Sentence | denotes | Posttranscriptional regulation of macrophage tissue factor expression by antioxidants. |
| T2 | 87-277 | Sentence | denotes | Tissue factor (TF) expression by cells of monocyte/macrophage lineage represents an important mechanism underlying the initiation of fibrin deposition at sites of extravascular inflammation. |
| T3 | 278-500 | Sentence | denotes | Recent evidence suggests a role for oxidant stress in the signalling pathway of various cell types by virtue of its ability to induce DNA binding of various transcription factors, including nuclear factor kappa B and AP-1. |
| T4 | 501-653 | Sentence | denotes | The effect of antioxidant treatment on lipopolysaccharide (LPS)-induced TF expression was examined in murine peritoneal macrophages and human monocytes. |
| T5 | 654-853 | Sentence | denotes | Both pyrrolidine dithiocarbamate, an oxidant scavenger, and N-acetyl-cysteine, a precursor of the endogenous antioxidant glutathione, inhibited stimulation of macrophage procoagulant activity by LPS. |
| T6 | 854-1024 | Sentence | denotes | Northern blot analysis showed that neither of these agents reduced LPS-stimulated TF mRNA accumulation, thereby suggesting a posttranscriptional mechanism for the effect. |
| T7 | 1025-1245 | Sentence | denotes | Immunofluorescence studies of human monocytes using polyclonal anti-TF antibody showed that N-acetyl-cysteine treatment prevented the characteristic plasmalemmal localization of TF antigen that occurs in response to LPS. |
| T8 | 1246-1450 | Sentence | denotes | Western blot analysis showed that N-acetyl-cysteine reduced the accumulation of the 47-kD mature glycoprotein in LPS-treated cells, a finding consistent with the results of the immunofluorescence studies. |
| T9 | 1451-1546 | Sentence | denotes | Furthermore, these conditions did not result in an accumulation of the less mature forms of TF. |
| T10 | 1547-1713 | Sentence | denotes | When considered together, these data suggest that antioxidants exert their effects by impairing translation and/or by causing degradation of newly translated protein. |
| T11 | 1714-1907 | Sentence | denotes | The effect of antioxidants on tumor necrosis factor appeared to be species specific, with no effect on LPS-induced tumor necrosis factor in murine cells, but with inhibition in human monocytes. |
| T12 | 1908-2071 | Sentence | denotes | The posttranscriptional effect of antioxidants on TF expression data suggests a novel mechanism whereby these agents might modulate monocyte/macrophage activation. |
| T1 | 0-86 | Sentence | denotes | Posttranscriptional regulation of macrophage tissue factor expression by antioxidants. |
| T2 | 87-277 | Sentence | denotes | Tissue factor (TF) expression by cells of monocyte/macrophage lineage represents an important mechanism underlying the initiation of fibrin deposition at sites of extravascular inflammation. |
| T3 | 278-500 | Sentence | denotes | Recent evidence suggests a role for oxidant stress in the signalling pathway of various cell types by virtue of its ability to induce DNA binding of various transcription factors, including nuclear factor kappa B and AP-1. |
| T4 | 501-653 | Sentence | denotes | The effect of antioxidant treatment on lipopolysaccharide (LPS)-induced TF expression was examined in murine peritoneal macrophages and human monocytes. |
| T5 | 654-853 | Sentence | denotes | Both pyrrolidine dithiocarbamate, an oxidant scavenger, and N-acetyl-cysteine, a precursor of the endogenous antioxidant glutathione, inhibited stimulation of macrophage procoagulant activity by LPS. |
| T6 | 854-1024 | Sentence | denotes | Northern blot analysis showed that neither of these agents reduced LPS-stimulated TF mRNA accumulation, thereby suggesting a posttranscriptional mechanism for the effect. |
| T7 | 1025-1245 | Sentence | denotes | Immunofluorescence studies of human monocytes using polyclonal anti-TF antibody showed that N-acetyl-cysteine treatment prevented the characteristic plasmalemmal localization of TF antigen that occurs in response to LPS. |
| T8 | 1246-1450 | Sentence | denotes | Western blot analysis showed that N-acetyl-cysteine reduced the accumulation of the 47-kD mature glycoprotein in LPS-treated cells, a finding consistent with the results of the immunofluorescence studies. |
| T9 | 1451-1546 | Sentence | denotes | Furthermore, these conditions did not result in an accumulation of the less mature forms of TF. |
| T10 | 1547-1713 | Sentence | denotes | When considered together, these data suggest that antioxidants exert their effects by impairing translation and/or by causing degradation of newly translated protein. |
| T11 | 1714-1907 | Sentence | denotes | The effect of antioxidants on tumor necrosis factor appeared to be species specific, with no effect on LPS-induced tumor necrosis factor in murine cells, but with inhibition in human monocytes. |
| T12 | 1908-2071 | Sentence | denotes | The posttranscriptional effect of antioxidants on TF expression data suggests a novel mechanism whereby these agents might modulate monocyte/macrophage activation. |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 45-58 | protein | denotes | tissue factor |
| T2 | 87-100 | protein | denotes | Tissue factor |
| T3 | 102-104 | protein | denotes | TF |
| T4 | 129-156 | cell_type | denotes | monocyte/macrophage lineage |
| T5 | 220-226 | protein | denotes | fibrin |
| T6 | 435-456 | protein | denotes | transcription factors |
| T7 | 468-490 | protein | denotes | nuclear factor kappa B |
| T8 | 495-499 | protein | denotes | AP-1 |
| T9 | 573-575 | protein | denotes | TF |
| T10 | 603-632 | cell_type | denotes | murine peritoneal macrophages |
| T11 | 637-652 | cell_type | denotes | human monocytes |
| T12 | 936-938 | protein | denotes | TF |
| T13 | 1055-1070 | cell_type | denotes | human monocytes |
| T14 | 1088-1104 | protein | denotes | anti-TF antibody |
| T15 | 1203-1213 | protein | denotes | TF antigen |
| T16 | 1330-1355 | protein | denotes | 47-kD mature glycoprotein |
| T17 | 1359-1376 | cell_line | denotes | LPS-treated cells |
| T18 | 1543-1545 | protein | denotes | TF |
| T19 | 1694-1712 | protein | denotes | translated protein |
| T20 | 1744-1765 | protein | denotes | tumor necrosis factor |
| T21 | 1891-1906 | cell_type | denotes | human monocytes |
| T22 | 1958-1960 | protein | denotes | TF |
| T23 | 2040-2048 | cell_type | denotes | monocyte |
| T24 | 2048-2059 | cell_type | denotes | /macrophage |
semrep-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| E1-ti-1 | 20-30 | cui:C0851285 | denotes | regulation |
| E2-ti-1 | 34-44 | cui:C0024432 | denotes | macrophage |
| E3-ti-1 | 45-58 | cui:C0040048 | denotes | tissue factor |
| E4-ti-1 | 59-69 | cui:C0185117 | denotes | expression |
| E5-ti-1 | 73-85 | cui:C0003402 | denotes | antioxidants |
| T1 | 20-30 | INTERACTS_WITH | denotes | regulation |
| T2 | 34-58 | PART_OF | denotes | macrophage tissue factor |
| E1-ab-1 | 87-100 | cui:C0040048 | denotes | Tissue factor |
| E2-ab-1 | 106-116 | cui:C0185117 | denotes | expression |
| E3-ab-1 | 120-125 | cui:C0007634 | denotes | cells |
| E4-ab-1 | 129-148 | cui:C1148382 | denotes | monocyte/macrophage |
| E5-ab-1 | 181-190 | cui:C0441712 | denotes | mechanism |
| E6-ab-1 | 220-237 | cui:C0333565 | denotes | fibrin deposition |
| E7-ab-1 | 241-246 | cui:C0205145 | denotes | sites |
| E8-ab-1 | 264-276 | cui:C0021368 | denotes | inflammation |
| E1-ab-2 | 278-284 | cui:C0332185 | denotes | Recent |
| E2-ab-2 | 305-309 | cui:C0035820 | denotes | role |
| E3-ab-2 | 314-321 | cui:C0085403 | denotes | oxidant |
| E4-ab-2 | 322-328 | cui:C0038435 | denotes | stress |
| E5-ab-2 | 336-354 | cui:C0086982 | denotes | signalling pathway |
| E6-ab-2 | 366-376 | cui:C0007634 | denotes | cell types |
| E7-ab-2 | 394-401 | cui:C0085732 | denotes | ability |
| E8-ab-2 | 412-423 | cui:C1148673 | denotes | DNA binding |
| E9-ab-2 | 435-456 | cui:C0040648 | denotes | transcription factors |
| E10-ab-2 | 468-490 | cui:C0079904 | denotes | nuclear factor kappa B |
| E11-ab-2 | 495-499 | cui:C0002059 | denotes | AP-1 |
| E1-ab-3 | 505-511 | cui:C1280500 | denotes | effect |
| E2-ab-3 | 515-526 | cui:C0003402 | denotes | antioxidant |
| E3-ab-3 | 540-558 | cui:C0023810 | denotes | lipopolysaccharide |
| E4-ab-3 | 565-572 | cui:C0205263 | denotes | induced |
| E5-ab-3 | 573-575 | cui:C0040048 | denotes | TF |
| E6-ab-3 | 576-586 | cui:C0185117 | denotes | expression |
| E7-ab-3 | 603-609 | cui:C0026809 | denotes | murine |
| E8-ab-3 | 610-632 | cui:C0206190 | denotes | peritoneal macrophages |
| E9-ab-3 | 637-642 | cui:C0020114 | denotes | human |
| E10-ab-3 | 643-652 | cui:C0026473 | denotes | monocytes |
| T3 | 603-632 | PART_OF | denotes | murine peritoneal macrophages |
| T4 | 600-602 | LOCATION_OF | denotes | in |
| T5 | 600-602 | LOCATION_OF | denotes | in |
| T6 | 637-652 | PART_OF | denotes | human monocytes |
| E1-ab-4 | 659-686 | cui:C0163305 | denotes | pyrrolidine dithiocarbamate |
| E2-ab-4 | 691-698 | cui:C0085403 | denotes | oxidant |
| E3-ab-4 | 699-708 | cui:C1003377 | denotes | scavenger |
| E4-ab-4 | 714-731 | cui:C0001047 | denotes | N-acetyl-cysteine |
| E5-ab-4 | 752-762 | cui:C0205227 | denotes | endogenous |
| E6-ab-4 | 763-774 | cui:C0003402 | denotes | antioxidant |
| E7-ab-4 | 775-786 | cui:C0017817 | denotes | glutathione |
| E8-ab-4 | 798-809 | cui:C1292856 | denotes | stimulation |
| E9-ab-4 | 813-845 | cui:C0065494 | denotes | macrophage procoagulant activity |
| E10-ab-4 | 849-852 | cui:C0023810 | denotes | LPS |
| T7 | 798-809 | STIMULATES | denotes | stimulation |
| E1-ab-5 | 854-876 | cui:C0005861 | denotes | Northern blot analysis |
| E2-ab-5 | 906-912 | cui:C0450442 | denotes | agents |
| E3-ab-5 | 921-924 | cui:C0023810 | denotes | LPS |
| E4-ab-5 | 936-938 | cui:C0040048 | denotes | TF |
| E5-ab-5 | 939-943 | cui:C0035696 | denotes | mRNA |
| E6-ab-5 | 999-1008 | cui:C0441712 | denotes | mechanism |
| E7-ab-5 | 1017-1023 | cui:C1280500 | denotes | effect |
| E1-ab-6 | 1025-1043 | cui:C0079603 | denotes | Immunofluorescence |
| E2-ab-6 | 1055-1060 | cui:C0020114 | denotes | human |
| E3-ab-6 | 1061-1070 | cui:C0026473 | denotes | monocytes |
| E4-ab-6 | 1093-1104 | cui:C0302073 | denotes | TF antibody |
| E5-ab-6 | 1117-1134 | cui:C0001047 | denotes | N-acetyl-cysteine |
| E6-ab-6 | 1159-1173 | cui:C1521970 | denotes | characteristic |
| E7-ab-6 | 1174-1186 | cui:C0007603 | denotes | plasmalemmal |
| E8-ab-6 | 1187-1199 | cui:C0475264 | denotes | localization |
| E9-ab-6 | 1203-1205 | cui:C0040048 | denotes | TF |
| E10-ab-6 | 1206-1213 | cui:C0003320 | denotes | antigen |
| E11-ab-6 | 1229-1237 | cui:C0871261 | denotes | response |
| E12-ab-6 | 1241-1244 | cui:C0023810 | denotes | LPS |
| T8 | 1055-1070 | PART_OF | denotes | human monocytes |
| E1-ab-7 | 1246-1267 | cui:C0949466 | denotes | Western blot analysis |
| E2-ab-7 | 1280-1297 | cui:C0001047 | denotes | N-acetyl-cysteine |
| E3-ab-7 | 1336-1342 | cui:C0205286 | denotes | mature |
| E4-ab-7 | 1343-1355 | cui:C0017968 | denotes | glycoprotein |
| E5-ab-7 | 1359-1362 | cui:C0023810 | denotes | LPS |
| E6-ab-7 | 1363-1370 | cui:C1522326 | denotes | treated |
| E7-ab-7 | 1371-1376 | cui:C0007634 | denotes | cells |
| E8-ab-7 | 1380-1387 | cui:C0243095 | denotes | finding |
| E9-ab-7 | 1408-1415 | cui:C1274040 | denotes | results |
| E10-ab-7 | 1423-1441 | cui:C0079603 | denotes | immunofluorescence |
| E11-ab-7 | 1442-1449 | cui:C0008972 | denotes | studies |
| T9 | 1356-1358 | LOCATION_OF | denotes | in |
| E1-ab-8 | 1470-1480 | cui:C0348080 | denotes | conditions |
| E2-ab-8 | 1485-1488 | cui:C1518422 | denotes | not |
| E3-ab-8 | 1527-1533 | cui:C0205286 | denotes | mature |
| E4-ab-8 | 1534-1539 | cui:C0376315 | denotes | forms |
| E5-ab-8 | 1543-1545 | cui:C0040048 | denotes | TF |
| E1-ab-9 | 1579-1583 | cui:C1511726 | denotes | data |
| E2-ab-9 | 1597-1609 | cui:C0003402 | denotes | antioxidants |
| E3-ab-9 | 1622-1629 | cui:C1280500 | denotes | effects |
| E4-ab-9 | 1633-1642 | cui:C0221099 | denotes | impairing |
| E5-ab-9 | 1643-1654 | cui:C0040711 | denotes | translation |
| E6-ab-9 | 1665-1672 | cui:C0678227 | denotes | causing |
| E7-ab-9 | 1673-1684 | cui:C0243125 | denotes | degradation |
| E8-ab-9 | 1688-1693 | cui:C0750546 | denotes | newly |
| E9-ab-9 | 1694-1704 | cui:C0040710 | denotes | translated |
| E10-ab-9 | 1705-1712 | cui:C0033684 | denotes | protein |
| E1-ab-10 | 1718-1724 | cui:C1280500 | denotes | effect |
| E2-ab-10 | 1728-1740 | cui:C0003402 | denotes | antioxidants |
| E3-ab-10 | 1744-1765 | cui:C1456820 | denotes | tumor necrosis factor |
| E4-ab-10 | 1781-1797 | cui:C0037783 | denotes | species specific |
| E5-ab-10 | 1807-1813 | cui:C1280500 | denotes | effect |
| E6-ab-10 | 1817-1820 | cui:C0023810 | denotes | LPS |
| E7-ab-10 | 1821-1828 | cui:C0205263 | denotes | induced |
| E8-ab-10 | 1829-1850 | cui:C1456820 | denotes | tumor necrosis factor |
| E9-ab-10 | 1854-1860 | cui:C0026809 | denotes | murine |
| E10-ab-10 | 1861-1866 | cui:C0007634 | denotes | cells |
| E11-ab-10 | 1891-1896 | cui:C0020114 | denotes | human |
| E12-ab-10 | 1897-1906 | cui:C0026473 | denotes | monocytes |
| T10 | 1718-1724 | INTERACTS_WITH | denotes | effect |
| T11 | 1854-1866 | PART_OF | denotes | murine cells |
| T12 | 1851-1853 | LOCATION_OF | denotes | in |
| T13 | 1891-1906 | PART_OF | denotes | human monocytes |
| T14 | 1888-1890 | LOCATION_OF | denotes | in |
| E1-ab-11 | 1932-1938 | cui:C1280500 | denotes | effect |
| E2-ab-11 | 1942-1954 | cui:C0003402 | denotes | antioxidants |
| E3-ab-11 | 1958-1960 | cui:C0040048 | denotes | TF |
| E4-ab-11 | 1961-1971 | cui:C0185117 | denotes | expression |
| E5-ab-11 | 1972-1976 | cui:C1511726 | denotes | data |
| E6-ab-11 | 1988-1993 | cui:C0679622 | denotes | novel |
| E7-ab-11 | 1994-2003 | cui:C0441712 | denotes | mechanism |
| E8-ab-11 | 2018-2024 | cui:C0450442 | denotes | agents |
| E9-ab-11 | 2040-2048 | cui:C0026473 | denotes | monocyte |
| E10-ab-11 | 2049-2070 | cui:C0024426 | denotes | macrophage activation |
| T15 | 2031-2039 | AFFECTS | denotes | modulate |
| R1 | E5-ti-1 | T1 | subjectOf | antioxidants,regulation |
| R2 | E3-ti-1 | T1 | objectOf | tissue factor,regulation |
| R3 | E3-ti-1 | T2 | subjectOf | tissue factor,macrophage tissue factor |
| R4 | E2-ti-1 | T2 | objectOf | macrophage,macrophage tissue factor |
| R5 | E8-ab-3 | T3 | subjectOf | peritoneal macrophages,murine peritoneal macrophages |
| R6 | E7-ab-3 | T3 | objectOf | murine,murine peritoneal macrophages |
| R7 | E8-ab-3 | T4 | subjectOf | peritoneal macrophages,in |
| R8 | E5-ab-3 | T4 | objectOf | TF,in |
| R9 | E10-ab-3 | T5 | subjectOf | monocytes,in |
| R10 | E5-ab-3 | T5 | objectOf | TF,in |
| R11 | E10-ab-3 | T6 | subjectOf | monocytes,human monocytes |
| R12 | E9-ab-3 | T6 | objectOf | human,human monocytes |
| R13 | E10-ab-4 | T7 | subjectOf | LPS,stimulation |
| R14 | E9-ab-4 | T7 | objectOf | macrophage procoagulant activity,stimulation |
| R15 | E3-ab-6 | T8 | subjectOf | monocytes,human monocytes |
| R16 | E2-ab-6 | T8 | objectOf | human,human monocytes |
| R17 | E7-ab-7 | T9 | subjectOf | cells,in |
| R18 | E4-ab-7 | T9 | objectOf | glycoprotein,in |
| R19 | E2-ab-10 | T10 | subjectOf | antioxidants,effect |
| R20 | E3-ab-10 | T10 | objectOf | tumor necrosis factor,effect |
| R21 | E10-ab-10 | T11 | subjectOf | cells,murine cells |
| R22 | E9-ab-10 | T11 | objectOf | murine,murine cells |
| R23 | E10-ab-10 | T12 | subjectOf | cells,in |
| R24 | E8-ab-10 | T12 | objectOf | tumor necrosis factor,in |
| R25 | E12-ab-10 | T13 | subjectOf | monocytes,human monocytes |
| R26 | E11-ab-10 | T13 | objectOf | human,human monocytes |
| R27 | E12-ab-10 | T14 | subjectOf | monocytes,in |
| R28 | E8-ab-10 | T14 | objectOf | tumor necrosis factor,in |
| R29 | E2-ab-11 | T15 | subjectOf | antioxidants,modulate |
| R30 | E10-ab-11 | T15 | objectOf | macrophage activation,modulate |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-86 | Sentence | denotes | Posttranscriptional regulation of macrophage tissue factor expression by antioxidants. |
| S2 | 87-277 | Sentence | denotes | Tissue factor (TF) expression by cells of monocyte/macrophage lineage represents an important mechanism underlying the initiation of fibrin deposition at sites of extravascular inflammation. |
| S3 | 278-500 | Sentence | denotes | Recent evidence suggests a role for oxidant stress in the signalling pathway of various cell types by virtue of its ability to induce DNA binding of various transcription factors, including nuclear factor kappa B and AP-1. |
| S4 | 501-653 | Sentence | denotes | The effect of antioxidant treatment on lipopolysaccharide (LPS)-induced TF expression was examined in murine peritoneal macrophages and human monocytes. |
| S5 | 654-853 | Sentence | denotes | Both pyrrolidine dithiocarbamate, an oxidant scavenger, and N-acetyl-cysteine, a precursor of the endogenous antioxidant glutathione, inhibited stimulation of macrophage procoagulant activity by LPS. |
| S6 | 854-1024 | Sentence | denotes | Northern blot analysis showed that neither of these agents reduced LPS-stimulated TF mRNA accumulation, thereby suggesting a posttranscriptional mechanism for the effect. |
| S7 | 1025-1245 | Sentence | denotes | Immunofluorescence studies of human monocytes using polyclonal anti-TF antibody showed that N-acetyl-cysteine treatment prevented the characteristic plasmalemmal localization of TF antigen that occurs in response to LPS. |
| S8 | 1246-1450 | Sentence | denotes | Western blot analysis showed that N-acetyl-cysteine reduced the accumulation of the 47-kD mature glycoprotein in LPS-treated cells, a finding consistent with the results of the immunofluorescence studies. |
| S9 | 1451-1546 | Sentence | denotes | Furthermore, these conditions did not result in an accumulation of the less mature forms of TF. |
| S10 | 1547-1713 | Sentence | denotes | When considered together, these data suggest that antioxidants exert their effects by impairing translation and/or by causing degradation of newly translated protein. |
| S11 | 1714-1907 | Sentence | denotes | The effect of antioxidants on tumor necrosis factor appeared to be species specific, with no effect on LPS-induced tumor necrosis factor in murine cells, but with inhibition in human monocytes. |
| S12 | 1908-2071 | Sentence | denotes | The posttranscriptional effect of antioxidants on TF expression data suggests a novel mechanism whereby these agents might modulate monocyte/macrophage activation. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 34-69 | NP | denotes | macrophage tissue factor expression |
| C2 | 73-85 | NP | denotes | antioxidants |
| C3 | 87-116 | NP | denotes | Tissue factor (TF) expression |
| C4 | 314-376 | NP | denotes | oxidant stress in the signalling pathway of various cell types |
| C5 | 390-393 | NP | denotes | its |
| C6 | 659-686 | NP | denotes | pyrrolidine dithiocarbamate |
| C7 | 688-708 | NP | denotes | an oxidant scavenger |
| C8 | 714-731 | NP | denotes | N-acetyl-cysteine |
| C9 | 733-786 | NP | denotes | a precursor of the endogenous antioxidant glutathione |
| C10 | 849-852 | NP | denotes | LPS |
| C11 | 1055-1070 | NP | denotes | human monocytes |
| C12 | 1155-1213 | NP | denotes | the characteristic plasmalemmal localization of TF antigen |
| C13 | 1214-1218 | NP | denotes | that |
| C14 | 1241-1244 | NP | denotes | LPS |
| C15 | 1280-1297 | NP | denotes | N-acetyl-cysteine |
| C16 | 1597-1609 | NP | denotes | antioxidants |
| C17 | 1616-1621 | NP | denotes | their |
| C18 | 1728-1740 | NP | denotes | antioxidants |
| C19 | 1891-1906 | NP | denotes | human monocytes |
| C20 | 1942-1954 | NP | denotes | antioxidants |
| C21 | 1958-1971 | NP | denotes | TF expression |
| C22 | 1986-2003 | NP | denotes | a novel mechanism |
| C23 | 2004-2011 | NP | denotes | whereby |
| C24 | 2012-2024 | NP | denotes | these agents |
| R1 | C3 | C1 | coref-ident | Tissue factor (TF) expression,macrophage tissue factor expression |
| R2 | C5 | C4 | coref-pron | its,oxidant stress in the signalling pathway of various cell types |
| R3 | C7 | C6 | coref-appos | an oxidant scavenger,pyrrolidine dithiocarbamate |
| R4 | C9 | C8 | coref-appos | a precursor of the endogenous antioxidant glutathione,N-acetyl-cysteine |
| R5 | C13 | C12 | coref-relat | that,the characteristic plasmalemmal localization of TF antigen |
| R6 | C14 | C10 | coref-ident | LPS,LPS |
| R7 | C15 | C8 | coref-ident | N-acetyl-cysteine,N-acetyl-cysteine |
| R8 | C16 | C2 | coref-ident | antioxidants,antioxidants |
| R9 | C17 | C16 | coref-pron | their,antioxidants |
| R10 | C18 | C16 | coref-ident | antioxidants,antioxidants |
| R11 | C19 | C11 | coref-ident | human monocytes,human monocytes |
| R12 | C20 | C18 | coref-ident | antioxidants,antioxidants |
| R13 | C21 | C3 | coref-ident | TF expression,Tissue factor (TF) expression |
| R14 | C23 | C22 | coref-relat | whereby,a novel mechanism |
| R15 | C24 | C20 | coref-ident | these agents,antioxidants |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-30 | other_name | denotes | Posttranscriptional regulation |
| T2 | 34-44 | other_name | denotes | macrophage |
| T3 | 45-58 | protein_family_or_group | denotes | tissue factor |
| T4 | 73-85 | other_organic_compound | denotes | antioxidants |
| T5 | 87-100 | protein_family_or_group | denotes | Tissue factor |
| T6 | 102-104 | protein_family_or_group | denotes | TF |
| T7 | 129-156 | cell_type | denotes | monocyte/macrophage lineage |
| T8 | 220-226 | protein_molecule | denotes | fibrin |
| T9 | 250-276 | other_name | denotes | extravascular inflammation |
| T10 | 412-423 | other_name | denotes | DNA binding |
| T11 | 435-456 | protein_family_or_group | denotes | transcription factors |
| T12 | 468-490 | protein_molecule | denotes | nuclear factor kappa B |
| T13 | 495-499 | protein_molecule | denotes | AP-1 |
| T14 | 540-558 | lipid | denotes | lipopolysaccharide |
| T15 | 560-563 | lipid | denotes | LPS |
| T16 | 573-575 | protein_family_or_group | denotes | TF |
| T17 | 603-632 | cell_type | denotes | murine peritoneal macrophages |
| T18 | 637-652 | cell_type | denotes | human monocytes |
| T19 | 659-686 | other_organic_compound | denotes | pyrrolidine dithiocarbamate |
| T20 | 691-708 | other_organic_compound | denotes | oxidant scavenger |
| T21 | 714-731 | amino_acid_monomer | denotes | N-acetyl-cysteine |
| T22 | 752-774 | other_organic_compound | denotes | endogenous antioxidant |
| T23 | 775-786 | peptide | denotes | glutathione |
| T24 | 849-852 | lipid | denotes | LPS |
| T25 | 854-876 | other_name | denotes | Northern blot analysis |
| T26 | 921-924 | lipid | denotes | LPS |
| T27 | 936-938 | protein_family_or_group | denotes | TF |
| T28 | 1025-1051 | other_name | denotes | Immunofluorescence studies |
| T29 | 1055-1070 | cell_type | denotes | human monocytes |
| T30 | 1088-1093 | protein_family_or_group | denotes | anti- |
| T31 | 1093-1095 | protein_family_or_group | denotes | TF |
| T32 | 1117-1134 | amino_acid_monomer | denotes | N-acetyl-cysteine |
| T33 | 1203-1205 | protein_family_or_group | denotes | TF |
| T34 | 1241-1244 | lipid | denotes | LPS |
| T35 | 1280-1297 | amino_acid_monomer | denotes | N-acetyl-cysteine |
| T36 | 1330-1355 | protein_molecule | denotes | 47-kD mature glycoprotein |
| T37 | 1359-1362 | lipid | denotes | LPS |
| T38 | 1423-1449 | other_name | denotes | immunofluorescence studies |
| T39 | 1543-1545 | protein_family_or_group | denotes | TF |
| T40 | 1597-1609 | other_organic_compound | denotes | antioxidants |
| T41 | 1694-1712 | protein_family_or_group | denotes | translated protein |
| T42 | 1728-1740 | other_organic_compound | denotes | antioxidants |
| T43 | 1744-1765 | protein_family_or_group | denotes | tumor necrosis factor |
| T44 | 1817-1820 | lipid | denotes | LPS |
| T45 | 1891-1906 | cell_type | denotes | human monocytes |
| T46 | 1912-1938 | other_name | denotes | posttranscriptional effect |
| T47 | 1942-1954 | other_organic_compound | denotes | antioxidants |
| T48 | 1958-1960 | protein_family_or_group | denotes | TF |
| T49 | 2040-2048 | cell_type | denotes | monocyte |
| T50 | 2048-2059 | cell_type | denotes | /macrophage |
metamap-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1598-1610 | C0003402 | denotes | ntioxidants |
| T2 | 764-775 | C0003402 | denotes | ntioxidant |
| T3 | 74-86 | C0003402 | denotes | ntioxidants. |
| T4 | 35-52 | C0019612 | denotes | acrophage tissue |
| T5 | 2050-2060 | C0024432 | denotes | acrophage |
| T6 | 35-45 | C0024432 | denotes | acrophage |
| T7 | 1-31 | C1514248 | denotes | osttranscriptional regulation |
| T8 | 1962-1972 | C0185117 | denotes | xpression |
| T9 | 577-587 | C0185117 | denotes | xpression |
| T10 | 107-117 | C0185117 | denotes | xpression |
| T11 | 60-70 | C0185117 | denotes | xpression |
| T12 | 1959-1961 | C1333522 | denotes | F |
| T13 | 1544-1546 | C1333522 | denotes | F. |
| T14 | 1204-1206 | C1333522 | denotes | F |
| T15 | 937-939 | C1333522 | denotes | F |
| T16 | 574-576 | C1333522 | denotes | F |
| T17 | 46-59 | C1333522 | denotes | issue factor |
| T18 | 53-59 | C1521761 | denotes | actor |
| T19 | 1818-1821 | C0023810 | denotes | PS- |
| T20 | 1360-1363 | C0023810 | denotes | PS- |
| T21 | 1242-1245 | C0023810 | denotes | PS. |
| T22 | 922-925 | C0023810 | denotes | PS- |
| T23 | 850-853 | C0023810 | denotes | PS. |
| T24 | 541-559 | C0023810 | denotes | ipopolysaccharide |
| T25 | 2041-2049 | C0026473 | denotes | onocyte/ |
| T26 | 1898-1907 | C0026473 | denotes | onocytes. |
| T27 | 1062-1071 | C0026473 | denotes | onocytes |
| T28 | 644-653 | C0026473 | denotes | onocytes. |
| T29 | 130-138 | C0026473 | denotes | onocyte/ |
| T30 | 1855-1861 | C0026809 | denotes | urine |
| T31 | 604-610 | C0026809 | denotes | urine |
| T32 | 1892-1896 | C0086418 | denotes | uman |
| T33 | 638-643 | C0086418 | denotes | uman |
| T34 | 1281-1298 | C0001047 | denotes | -acetyl-cysteine |
| T35 | 1118-1135 | C0001047 | denotes | -acetyl-cysteine |
| T36 | 715-732 | C0001047 | denotes | -acetyl-cysteine, |
| T37 | 692-699 | C0085403 | denotes | xidant |
| T38 | 315-322 | C0085403 | denotes | xidant |
| T39 | 496-500 | C0085828 | denotes | P-1. |
| T40 | 1247-1268 | C0949466 | denotes | estern blot analysis |
| T41 | 1978-1986 | C1705535 | denotes | uggests |
| T42 | 1585-1592 | C1705535 | denotes | uggest |
| T43 | 967-977 | C1705535 | denotes | uggesting |
| T44 | 295-303 | C1705535 | denotes | uggests |
| T45 | 611-633 | C0206190 | denotes | eritoneal macrophages |
| T46 | 1695-1705 | C0040710 | denotes | ranslated |
| T47 | 1644-1655 | C0597295 | denotes | ranslation |
| T48 | 469-490 | C0079904 | denotes | uclear factor kappa B |
| T49 | 855-877 | C0005861 | denotes | orthern blot analysis |
| T50 | 337-355 | C0037083 | denotes | ignalling pathway |
| T51 | 2050-2071 | C0024426 | denotes | acrophage activation. |
| T52 | 395-402 | C0085732 | denotes | bility |
| T53 | 814-846 | C0065494 | denotes | acrophage procoagulant activity |
| T54 | 940-944 | C0035696 | denotes | RNA |
| T55 | 776-787 | C0017817 | denotes | lutathione, |
| T56 | 1269-1275 | C1547282 | denotes | howed |
| T57 | 1106-1112 | C1547282 | denotes | howed |
| T58 | 878-884 | C1547282 | denotes | howed |
| T59 | 1995-2004 | C0441712 | denotes | echanism |
| T60 | 1000-1009 | C0441712 | denotes | echanism |
| T61 | 182-191 | C0441712 | denotes | echanism |
| T62 | 1808-1814 | C1280500 | denotes | ffect |
| T63 | 1623-1630 | C1280500 | denotes | ffects |
| T64 | 1018-1024 | C1280500 | denotes | ffect. |
| T65 | 1822-1829 | C0205263 | denotes | nduced |
| T66 | 566-572 | C0205263 | denotes | nduced |
| T67 | 406-411 | C0205263 | denotes | nduce |
| T68 | 1299-1306 | C0392756 | denotes | educed |
| T69 | 914-921 | C0392756 | denotes | educed |
| T70 | 265-277 | C0021368 | denotes | nflammation. |
| T71 | 413-416 | C0012854 | denotes | NA |
| T72 | 1344-1356 | C0017968 | denotes | lycoprotein |
| T73 | 1175-1186 | C0007603 | denotes | lasmalemmal |
| T74 | 1381-1388 | C0037088 | denotes | inding |
| T75 | 1973-1976 | C1511726 | denotes | ata |
| T76 | 1580-1583 | C1511726 | denotes | ata |
| T77 | 2019-2025 | C1254351 | denotes | gents |
| T78 | 907-913 | C1254351 | denotes | gents |
| T79 | 1862-1867 | C0007634 | denotes | ells, |
| T80 | 1372-1377 | C0007634 | denotes | ells, |
| T81 | 1136-1145 | C0087111 | denotes | reatment |
| T82 | 528-537 | C0087111 | denotes | reatment |
| T83 | 1424-1442 | C0079603 | denotes | mmunofluorescence |
| T84 | 1026-1043 | C0079603 | denotes | mmunofluorescence |
| T85 | 1528-1534 | C0205286 | denotes | ature |
| T86 | 1337-1342 | C0205286 | denotes | ature |
| T87 | 1782-1798 | C0037783 | denotes | pecies specific, |
| T88 | 1207-1214 | C0003320 | denotes | ntigen |
| T89 | 1611-1616 | C0015264 | denotes | xert |
| T90 | 459-468 | C0332257 | denotes | ncluding |
| T91 | 789-798 | C0311403 | denotes | nhibited |
| T92 | 2032-2039 | C0443264 | denotes | odulate |
| T93 | 1486-1489 | C1518422 | denotes | ot |
| T94 | 660-687 | C1313719 | denotes | yrrolidine dithiocarbamate, |
| T95 | 158-168 | C1882932 | denotes | epresents |
| T96 | 242-247 | C0205145 | denotes | ites |
| T97 | 1776-1778 | C1883351 | denotes | o |
| T98 | 1564-1572 | C1883357 | denotes | ogether, |
| T99 | 1072-1077 | C1524063 | denotes | sing |
| T100 | 1553-1563 | C0750591 | denotes | onsidered |
| T101 | 660-687 | C0163305 | denotes | yrrolidine dithiocarbamate, |
| T102 | 1767-1775 | C0700364 | denotes | ppeared |
| T103 | 1471-1481 | C1705253 | denotes | onditions |
| T104 | 1146-1155 | C0309872 | denotes | revented |
| T105 | 367-377 | C0449475 | denotes | ell types |
| T106 | 1094-1105 | C0302073 | denotes | F antibody |
| T107 | 286-294 | C0332120 | denotes | vidence |
| T108 | 700-709 | C1003377 | denotes | cavenger, |
| T109 | 1869-1872 | C0233535 | denotes | ut |
| T110 | 1878-1888 | C0021469 | denotes | nhibition |
| T111 | 1220-1226 | C2745955 | denotes | ccurs |
| T112 | 1230-1238 | C0871261 | denotes | esponse |
| T113 | 1389-1404 | C0332290 | denotes | onsistent with |
| T114 | 890-897 | C3274651 | denotes | either |
| T115 | 1656-1662 | C1706528 | denotes | nd/or |
| T116 | 592-600 | C0332128 | denotes | xamined |
| T117 | 306-310 | C1705810 | denotes | ole |
| T118 | 799-810 | C1292856 | denotes | timulation |
| T119 | 207-217 | C1158830 | denotes | nitiation |
| T120 | 736-745 | C1709634 | denotes | recursor |
| T121 | 1188-1200 | C1744691 | denotes | ocalization |
| T122 | 1666-1673 | C0678227 | denotes | ausing |
| T123 | 1689-1694 | C0750546 | denotes | ewly |
| T124 | 1535-1540 | C0348078 | denotes | orms |
| T125 | 1490-1496 | C1274040 | denotes | esult |
| T126 | 279-285 | C0332185 | denotes | ecent |
| T127 | 1989-1994 | C0205314 | denotes | ovel |
| T128 | 1364-1371 | C1522326 | denotes | reated |
| T129 | 221-238 | C0333565 | denotes | ibrin deposition |
| T130 | 926-936 | C1948023 | denotes | timulated |
| T131 | 1634-1643 | C0221099 | denotes | mpairing |
| T132 | 323-329 | C0038435 | denotes | tress |
| T133 | 753-763 | C0205227 | denotes | ndogenous |
| T134 | 1334-1336 | C1705240 | denotes | D |
| T135 | 1160-1174 | C1521970 | denotes | haracteristic |
| T136 | 88-94 | C0040300 | denotes | issue |
| T137 | 150-157 | C1881379 | denotes | ineage |