> top > docs > PubMed:7833306 > annotations

PubMed:7833306 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-111 Sentence denotes Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia.
TextSentencer_T2 112-123 Sentence denotes OBJECTIVES:
TextSentencer_T3 124-335 Sentence denotes Generalised maternal endothelial cell dysfunction appears to be an underlying problem in pre-eclampsia presumed to be caused, directly or indirectly, by one or more circulating factors derived from the placenta.
TextSentencer_T4 336-486 Sentence denotes Recently it has been suggested that tumour necrosis factor (TNF) may play an important role in pre-eclampsia and contribute to endothelial activation.
TextSentencer_T5 487-540 Sentence denotes This study was designed to investigate this proposal.
TextSentencer_T6 541-548 Sentence denotes DESIGN:
TextSentencer_T7 549-758 Sentence denotes Plasma TNF-alpha, IL-6 and both forms of soluble TNF receptors (p55 and p75 TNF-R) have been measured by ELISA in 31 pre-eclamptic patients and 31 pregnant controls matched for age, parity and gestational age.
TextSentencer_T8 759-767 Sentence denotes RESULTS:
TextSentencer_T9 768-994 Sentence denotes Levels of IL-6, TNF-alpha and soluble TNF-R (p55 and p75) were significantly higher in pre-eclamptic patients, compared with age and gestation matched controls with a wide variation in levels between pre-eclamptic individuals.
TextSentencer_T10 995-1092 Sentence denotes There was a correlation between levels of IL-6 and TNF or TNF-R and between TNF and TNF-R levels.
TextSentencer_T11 1093-1325 Sentence denotes However, when the pre-eclamptic patients were subdivided on the basis of the severity of their disease, the median values of plasma concentrations of IL-6, TNF-alpha and TNF-R were all higher in the group with lower platelet counts.
TextSentencer_T12 1326-1338 Sentence denotes CONCLUSIONS:
TextSentencer_T13 1339-1606 Sentence denotes These new findings are consistent with the concept that the maternal syndrome of pre-eclampsia is associated with endothelial dysfunction and provide evidence that at least part of this dysfunction could arise from excessive release of TNF-alpha into the circulation.
T1 0-111 Sentence denotes Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia.
T2 112-123 Sentence denotes OBJECTIVES:
T3 124-335 Sentence denotes Generalised maternal endothelial cell dysfunction appears to be an underlying problem in pre-eclampsia presumed to be caused, directly or indirectly, by one or more circulating factors derived from the placenta.
T4 336-486 Sentence denotes Recently it has been suggested that tumour necrosis factor (TNF) may play an important role in pre-eclampsia and contribute to endothelial activation.
T5 487-540 Sentence denotes This study was designed to investigate this proposal.
T6 541-548 Sentence denotes DESIGN:
T7 549-758 Sentence denotes Plasma TNF-alpha, IL-6 and both forms of soluble TNF receptors (p55 and p75 TNF-R) have been measured by ELISA in 31 pre-eclamptic patients and 31 pregnant controls matched for age, parity and gestational age.
T8 759-767 Sentence denotes RESULTS:
T9 768-994 Sentence denotes Levels of IL-6, TNF-alpha and soluble TNF-R (p55 and p75) were significantly higher in pre-eclamptic patients, compared with age and gestation matched controls with a wide variation in levels between pre-eclamptic individuals.
T10 995-1092 Sentence denotes There was a correlation between levels of IL-6 and TNF or TNF-R and between TNF and TNF-R levels.
T11 1093-1325 Sentence denotes However, when the pre-eclamptic patients were subdivided on the basis of the severity of their disease, the median values of plasma concentrations of IL-6, TNF-alpha and TNF-R were all higher in the group with lower platelet counts.
T12 1326-1338 Sentence denotes CONCLUSIONS:
T13 1339-1606 Sentence denotes These new findings are consistent with the concept that the maternal syndrome of pre-eclampsia is associated with endothelial dysfunction and provide evidence that at least part of this dysfunction could arise from excessive release of TNF-alpha into the circulation.

Preeclampsia

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 97-110 ORPHA:275555 denotes pre-eclampsia
PD-Preeclampsia-B_T2 213-226 ORPHA:275555 denotes pre-eclampsia
PD-Preeclampsia-B_T3 431-444 ORPHA:275555 denotes pre-eclampsia
PD-Preeclampsia-B_T4 666-688 ORPHA:275555 denotes pre-eclamptic patients
PD-Preeclampsia-B_T5 855-877 ORPHA:275555 denotes pre-eclamptic patients
PD-Preeclampsia-B_T6 1111-1133 ORPHA:275555 denotes pre-eclamptic patients
PD-Preeclampsia-B_T7 1420-1433 ORPHA:275555 denotes pre-eclampsia

Preeclampsia-compare

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 97-110 ORPHA:275555 denotes pre-eclampsia
PD-Preeclampsia-B_T2 213-226 ORPHA:275555 denotes pre-eclampsia
PD-Preeclampsia-B_T3 431-444 ORPHA:275555 denotes pre-eclampsia
PD-Preeclampsia-B_T4 666-679 ORPHA:275555 denotes pre-eclamptic
PD-Preeclampsia-B_T5 855-868 ORPHA:275555 denotes pre-eclamptic
PD-Preeclampsia-B_T6 968-981 ORPHA:275555 denotes pre-eclamptic
PD-Preeclampsia-B_T7 1111-1124 ORPHA:275555 denotes pre-eclamptic
PD-Preeclampsia-B_T8 1420-1433 ORPHA:275555 denotes pre-eclampsia

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 326-334 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta

preeclampsia_genes

Id Subject Object Predicate Lexical cue
PD-PreeclampsiaGenes-B_T1 0-13 HGNC:IL6 denotes Interleukin-6

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 326-334 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta