PubMed:7827107
Annnotations
GlyCosmos15-Species-PubTator
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 5 | 83-88 | Species | denotes | human | 9606 |
| 36 | 144-149 | Species | denotes | human | 9606 |
| 55 | 1321-1326 | Species | denotes | human | 9606 |
| 57 | 1522-1527 | Species | denotes | human | 9606 |
| 60 | 1776-1781 | Species | denotes | human | 9606 |
| 63 | 2036-2041 | Species | denotes | human | 9606 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 52-63 | Glycan | denotes | chondroitin | |
| T2 | 530-541 | Glycan | denotes | chondroitin | |
| T3 | 583-594 | Glycan | denotes | Chondroitin |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 52-63 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 530-541 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 583-594 | Glycan | denotes | Chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 2017-2032 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 52-63 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 530-541 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 583-594 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 2017-2032 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 89-95 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T2 | 150-156 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T3 | 266-272 | Body_part | denotes | Plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T4 | 518-524 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T5 | 574-580 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T6 | 1327-1333 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T7 | 1498-1504 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T8 | 1599-1605 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T9 | 1782-1788 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T10 | 1899-1905 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T11 | 2042-2048 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-96 | Sentence | denotes | Qualitative and quantitative studies of heparin and chondroitin sulfates in normal human plasma. |
| T2 | 97-265 | Sentence | denotes | Heparin was extracted and purified from normal human plasma, and full characterization of its structure and physico-chemical properties was achieved for the first time. |
| T3 | 266-453 | Sentence | denotes | Plasma was submitted to exhaustive proteolytic treatment with papain, trypsin, chymotrypsin, collagenase and pepsin, anion-exchange chromatography and precipitation with organic solvents. |
| T4 | 454-582 | Sentence | denotes | By this procedure, we recovered heparin (about 0.7 mg/100 ml of plasma) and chondroitin sulfate (about 0.1 mg/100 ml of plasma). |
| T5 | 583-819 | Sentence | denotes | Chondroitin sulfate has a peak molecular mass of about 15,630, and it is composed of about 60% nonsulfated disaccharide, 3.5% disaccharide 6-monosulfate and about 40% disaccharide 4-monosulfate, with a sulfate-to-carboxyl ratio of 0.41. |
| T6 | 820-956 | Sentence | denotes | Heparin, identified by agarose-gel electrophoresis, is constituted by about 40% slow-moving component and about 60% fast-moving species. |
| T7 | 957-1105 | Sentence | denotes | This glycosaminoglycan had a peak molecular mass of about 7000, and was identified as 'typical' heparin by its constituent disaccharide composition. |
| T8 | 1106-1290 | Sentence | denotes | About 70% of disaccharides were identified as trisulfated disaccharide, and about 18% as disulfated disaccharides, 3% as monosulfated disaccharides and 10% as nonsulfated disaccharide. |
| T9 | 1291-1685 | Sentence | denotes | Heparin extracted from normal human plasma has a high sulfate-to-carboxyl ratio (2.47) and in vitro anticoagulant activity of about 70 I.U. A more quantitative and statistical analysis performed on 10 ml of plasma obtained from 10 human healthy volunteers revealed a heparin level of 0.54 +/- 0.17 mg/100 ml plasma (mean +/- standard deviation) with a coefficient of variation of about +/- 32%. |
| T10 | 1686-1925 | Sentence | denotes | These findings demonstrate for the first time the presence of heparin molecules in normal human plasma and confirm the importance of adequate extraction processes to purify a molecule that strongly interacts with plasma protein components. |
| T11 | 1926-2049 | Sentence | denotes | This is discussed in light of other authors that described a polysaccharide molecule named heparan sulfate in human plasma. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 52-63 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 530-541 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 583-594 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 2017-2032 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 83-88 | OrganismTaxon | denotes | human | 9606 |
| T2 | 144-149 | OrganismTaxon | denotes | human | 9606 |
| T3 | 1321-1326 | OrganismTaxon | denotes | human | 9606 |
| T4 | 1522-1527 | OrganismTaxon | denotes | human | 9606 |
| T5 | 1776-1781 | OrganismTaxon | denotes | human | 9606 |
| T6 | 2036-2041 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 89-95 | Body_part | denotes | plasma | FMA:62970 |
| T2 | 150-156 | Body_part | denotes | plasma | FMA:62970 |
| T3 | 266-272 | Body_part | denotes | Plasma | FMA:62970 |
| T4 | 518-524 | Body_part | denotes | plasma | FMA:62970 |
| T5 | 574-580 | Body_part | denotes | plasma | FMA:62970 |
| T6 | 1327-1333 | Body_part | denotes | plasma | FMA:62970 |
| T7 | 1498-1504 | Body_part | denotes | plasma | FMA:62970 |
| T8 | 1599-1605 | Body_part | denotes | plasma | FMA:62970 |
| T9 | 1782-1788 | Body_part | denotes | plasma | FMA:62970 |
| T10 | 1899-1905 | Body_part | denotes | plasma | FMA:62970 |
| T11 | 2042-2048 | Body_part | denotes | plasma | FMA:62970 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 83-88 | OrganismTaxon | denotes | human | 9606 |
| T2 | 144-149 | OrganismTaxon | denotes | human | 9606 |
| T3 | 1321-1326 | OrganismTaxon | denotes | human | 9606 |
| T4 | 1522-1527 | OrganismTaxon | denotes | human | 9606 |
| T5 | 1776-1781 | OrganismTaxon | denotes | human | 9606 |
| T6 | 2036-2041 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 89-95 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T2 | 150-156 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T3 | 266-272 | Body_part | denotes | Plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T4 | 518-524 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T5 | 574-580 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T6 | 1327-1333 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T7 | 1498-1504 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T8 | 1599-1605 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T9 | 1782-1788 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T10 | 1899-1905 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T11 | 2042-2048 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |