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PubMed:7791512 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-120 Sentence denotes Physiological concentration of estradiol inhibits polymorphonuclear leukocyte chemotaxis via a receptor mediated system.
T2 121-219 Sentence denotes Estrogen exhibits a variety of actions, including immuno-modulatory effects, in vivo and in vitro.
T3 220-310 Sentence denotes The mechanism by which estrogen exerts its anti-inflammatory effect is not yet understood.
T4 311-459 Sentence denotes We investigated the possible mechanisms of estradiol acting via the polymorphonuclear leukocytes (PMNs), which are important in the immune response.
T5 460-638 Sentence denotes The agent, 17 beta-estradiol, but not 17 alpha-estradiol, significantly reduced PMNs chemotaxis to FMLP in a dose-dependent manner (control vs estrogen 10(-10)-(-6) M, P < 0.05).
T6 639-740 Sentence denotes Physiological concentrations of estradiol significantly reduced the chemotaxis of PMNs (10(-10) mol).
T7 741-941 Sentence denotes Pre-incubation with clomiphene or tamoxifen which are estrogen receptor antagonists, eliminated the inhibitory effect of 17 beta-estradiol on the chemotaxis of PMNs, restoring it to the control level.
T8 942-1060 Sentence denotes These observations suggest that 17 beta-estradiol suppressed the chemotaxis of PMNs by a receptor-dependent mechanism.
T9 1061-1229 Sentence denotes In addition, the level of estradiol in human plasma, which PMNs were drawn, showed a close, inverse correlation with the PMNs chemotaxis to FMLP (r = -0.821 p < 0.001).
T10 1230-1367 Sentence denotes Estrogen may modify the activity of neutrophils during the normal menstrual cycle, not only during pregnancy, and influence inflammation.
T1 0-120 Sentence denotes Physiological concentration of estradiol inhibits polymorphonuclear leukocyte chemotaxis via a receptor mediated system.
T2 121-219 Sentence denotes Estrogen exhibits a variety of actions, including immuno-modulatory effects, in vivo and in vitro.
T3 220-310 Sentence denotes The mechanism by which estrogen exerts its anti-inflammatory effect is not yet understood.
T4 311-459 Sentence denotes We investigated the possible mechanisms of estradiol acting via the polymorphonuclear leukocytes (PMNs), which are important in the immune response.
T5 460-638 Sentence denotes The agent, 17 beta-estradiol, but not 17 alpha-estradiol, significantly reduced PMNs chemotaxis to FMLP in a dose-dependent manner (control vs estrogen 10(-10)-(-6) M, P < 0.05).
T6 639-740 Sentence denotes Physiological concentrations of estradiol significantly reduced the chemotaxis of PMNs (10(-10) mol).
T7 741-941 Sentence denotes Pre-incubation with clomiphene or tamoxifen which are estrogen receptor antagonists, eliminated the inhibitory effect of 17 beta-estradiol on the chemotaxis of PMNs, restoring it to the control level.
T8 942-1060 Sentence denotes These observations suggest that 17 beta-estradiol suppressed the chemotaxis of PMNs by a receptor-dependent mechanism.
T9 1061-1229 Sentence denotes In addition, the level of estradiol in human plasma, which PMNs were drawn, showed a close, inverse correlation with the PMNs chemotaxis to FMLP (r = -0.821 p < 0.001).
T10 1230-1367 Sentence denotes Estrogen may modify the activity of neutrophils during the normal menstrual cycle, not only during pregnancy, and influence inflammation.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 50-77 cell_type denotes polymorphonuclear leukocyte
T2 379-407 cell_type denotes polymorphonuclear leukocytes
T3 409-413 cell_type denotes PMNs
T4 540-544 cell_type denotes PMNs
T5 721-725 cell_type denotes PMNs
T6 901-905 cell_type denotes PMNs
T7 1021-1025 cell_type denotes PMNs
T8 1100-1112 cell_type denotes human plasma
T9 1120-1124 cell_type denotes PMNs
T10 1182-1186 cell_type denotes PMNs
T11 1266-1277 cell_type denotes neutrophils

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-120 Sentence denotes Physiological concentration of estradiol inhibits polymorphonuclear leukocyte chemotaxis via a receptor mediated system.
S2 121-219 Sentence denotes Estrogen exhibits a variety of actions, including immuno-modulatory effects, in vivo and in vitro.
S3 220-310 Sentence denotes The mechanism by which estrogen exerts its anti-inflammatory effect is not yet understood.
S4 311-459 Sentence denotes We investigated the possible mechanisms of estradiol acting via the polymorphonuclear leukocytes (PMNs), which are important in the immune response.
S5 460-638 Sentence denotes The agent, 17 beta-estradiol, but not 17 alpha-estradiol, significantly reduced PMNs chemotaxis to FMLP in a dose-dependent manner (control vs estrogen 10(-10)-(-6) M, P < 0.05).
S6 639-740 Sentence denotes Physiological concentrations of estradiol significantly reduced the chemotaxis of PMNs (10(-10) mol).
S7 741-941 Sentence denotes Pre-incubation with clomiphene or tamoxifen which are estrogen receptor antagonists, eliminated the inhibitory effect of 17 beta-estradiol on the chemotaxis of PMNs, restoring it to the control level.
S8 942-1060 Sentence denotes These observations suggest that 17 beta-estradiol suppressed the chemotaxis of PMNs by a receptor-dependent mechanism.
S9 1061-1229 Sentence denotes In addition, the level of estradiol in human plasma, which PMNs were drawn, showed a close, inverse correlation with the PMNs chemotaxis to FMLP (r = -0.821 p < 0.001).
S10 1230-1367 Sentence denotes Estrogen may modify the activity of neutrophils during the normal menstrual cycle, not only during pregnancy, and influence inflammation.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 31-40 NP denotes estradiol
C1 0-40 NP denotes Physiological concentration of estradiol
C3 50-88 NP denotes polymorphonuclear leukocyte chemotaxis
C4 121-129 NP denotes Estrogen
C5 220-233 NP denotes The mechanism
C6 237-242 NP denotes which
C7 243-251 NP denotes estrogen
C8 259-262 NP denotes its
C10 354-363 NP denotes estradiol
C11 375-414 NP denotes the polymorphonuclear leukocytes (PMNs)
C9 327-414 NP denotes the possible mechanisms of estradiol acting via the polymorphonuclear leukocytes (PMNs)
C12 416-421 NP denotes which
C13 460-469 NP denotes The agent
C14 471-488 NP denotes 17 beta-estradiol
C15 540-563 NP denotes PMNs chemotaxis to FMLP
C17 671-680 NP denotes estradiol
C16 639-680 NP denotes Physiological concentrations of estradiol
C19 721-725 NP denotes PMNs
C18 703-725 NP denotes the chemotaxis of PMNs
C20 761-784 NP denotes clomiphene or tamoxifen
C21 785-790 NP denotes which
C22 862-879 NP denotes 17 beta-estradiol
C24 901-905 NP denotes PMNs
C23 883-905 NP denotes the chemotaxis of PMNs
C25 917-919 NP denotes it
C26 974-991 NP denotes 17 beta-estradiol
C28 1021-1025 NP denotes PMNs
C27 1003-1025 NP denotes the chemotaxis of PMNs
C29 1087-1096 NP denotes estradiol
C30 1100-1112 NP denotes human plasma
C31 1114-1119 NP denotes which
C32 1120-1124 NP denotes PMNs
C33 1178-1205 NP denotes the PMNs chemotaxis to FMLP
C34 1230-1238 NP denotes Estrogen
R1 C6 C5 coref-relat which,The mechanism
R2 C7 C4 coref-ident estrogen,Estrogen
R3 C8 C7 coref-pron its,estrogen
R4 C10 C2 coref-ident estradiol,estradiol
R5 C12 C9 coref-relat which,the possible mechanisms of estradiol acting via the polymorphonuclear leukocytes (PMNs)
R6 C14 C13 coref-appos 17 beta-estradiol,The agent
R7 C15 C3 coref-ident PMNs chemotaxis to FMLP,polymorphonuclear leukocyte chemotaxis
R8 C17 C10 coref-ident estradiol,estradiol
R9 C16 C1 coref-ident Physiological concentrations of estradiol,Physiological concentration of estradiol
R10 C19 C11 coref-ident PMNs,the polymorphonuclear leukocytes (PMNs)
R11 C18 C15 coref-ident the chemotaxis of PMNs,PMNs chemotaxis to FMLP
R12 C21 C20 coref-relat which,clomiphene or tamoxifen
R13 C22 C13 coref-ident 17 beta-estradiol,The agent
R14 C24 C19 coref-ident PMNs,PMNs
R15 C23 C18 coref-ident the chemotaxis of PMNs,the chemotaxis of PMNs
R16 C25 C23 coref-pron it,the chemotaxis of PMNs
R17 C26 C22 coref-ident 17 beta-estradiol,17 beta-estradiol
R18 C28 C24 coref-ident PMNs,PMNs
R19 C27 C23 coref-ident the chemotaxis of PMNs,the chemotaxis of PMNs
R20 C29 C17 coref-ident estradiol,estradiol
R21 C31 C30 coref-relat which,human plasma
R22 C32 C28 coref-ident PMNs,PMNs
R23 C33 C27 coref-ident the PMNs chemotaxis to FMLP,the chemotaxis of PMNs
R24 C34 C7 coref-ident Estrogen,estrogen

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 31-40 lipid denotes estradiol
T2 50-77 cell_type denotes polymorphonuclear leukocyte
T3 121-129 lipid denotes Estrogen
T4 171-196 other_name denotes immuno-modulatory effects
T5 263-287 other_name denotes anti-inflammatory effect
T6 354-363 lipid denotes estradiol
T7 379-407 cell_type denotes polymorphonuclear leukocytes
T8 409-413 cell_type denotes PMNs
T9 443-458 other_name denotes immune response
T10 471-479 lipid denotes 17 beta-
T11 479-488 lipid denotes estradiol
T12 498-507 lipid denotes 17 alpha-
T13 507-516 lipid denotes estradiol
T14 540-544 cell_type denotes PMNs
T15 559-563 lipid denotes FMLP
T16 569-590 other_name denotes dose-dependent manner
T17 671-680 lipid denotes estradiol
T18 721-725 cell_type denotes PMNs
T19 761-771 other_organic_compound denotes clomiphene
T20 775-784 other_organic_compound denotes tamoxifen
T21 862-870 lipid denotes 17 beta-
T22 870-879 lipid denotes estradiol
T23 887-897 other_name denotes chemotaxis
T24 901-905 cell_type denotes PMNs
T25 974-982 lipid denotes 17 beta-
T26 982-991 lipid denotes estradiol
T27 1007-1017 other_name denotes chemotaxis
T28 1021-1025 cell_type denotes PMNs
T29 1031-1059 other_name denotes receptor-dependent mechanism
T30 1087-1096 lipid denotes estradiol
T31 1100-1112 cell_type denotes human plasma
T32 1120-1124 cell_type denotes PMNs
T33 1182-1186 cell_type denotes PMNs
T34 1187-1197 other_name denotes chemotaxis
T35 1201-1205 lipid denotes FMLP
T36 1230-1238 lipid denotes Estrogen
T37 1266-1277 cell_type denotes neutrophils