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PubMed:7768941 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-109 Sentence denotes The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma.
T2 110-229 Sentence denotes We have identified an in vivo footprint over the PuF site on the translocated c-myc allele in Burkitt's lymphoma cells.
T3 230-292 Sentence denotes The PuF site on the silent normal c-myc allele was unoccupied.
T4 293-544 Sentence denotes We demonstrated by electrophoretic mobility shift assay, electrophoretic mobility shift assay with antibody, UV cross-linking followed by SDS-gel electrophoresis, and Western analysis that Nm23H2 in B cell nuclear extracts bound to the c-myc PuF site.
T5 545-763 Sentence denotes Transfection experiments with c-myc promoter constructs in both DHL-9 and Raji cells revealed that the PuF site functioned as a positive regulatory element in B cells with a drop in activity with mutation of this site.
T6 764-962 Sentence denotes Access to this site is blocked in the normal silent c-myc allele; these data suggest that the Nm23H2 protein is involved in deregulation of the translocated c-myc allele in Burkitt's lymphoma cells.
T1 0-109 Sentence denotes The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma.
T2 110-229 Sentence denotes We have identified an in vivo footprint over the PuF site on the translocated c-myc allele in Burkitt's lymphoma cells.
T3 230-292 Sentence denotes The PuF site on the silent normal c-myc allele was unoccupied.
T4 293-544 Sentence denotes We demonstrated by electrophoretic mobility shift assay, electrophoretic mobility shift assay with antibody, UV cross-linking followed by SDS-gel electrophoresis, and Western analysis that Nm23H2 in B cell nuclear extracts bound to the c-myc PuF site.
T5 545-763 Sentence denotes Transfection experiments with c-myc promoter constructs in both DHL-9 and Raji cells revealed that the PuF site functioned as a positive regulatory element in B cells with a drop in activity with mutation of this site.
T6 764-962 Sentence denotes Access to this site is blocked in the normal silent c-myc allele; these data suggest that the Nm23H2 protein is involved in deregulation of the translocated c-myc allele in Burkitt's lymphoma cells.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 4-24 protein denotes transcription factor
T2 26-32 protein denotes Nm23H2
T3 74-86 DNA denotes c-myc allele
T4 159-167 DNA denotes PuF site
T5 188-200 DNA denotes c-myc allele
T6 234-242 DNA denotes PuF site
T7 250-276 DNA denotes silent normal c-myc allele
T8 482-488 protein denotes Nm23H2
T9 535-543 DNA denotes PuF site
T10 575-600 DNA denotes c-myc promoter constructs
T11 609-614 cell_line denotes DHL-9
T12 619-629 cell_line denotes Raji cells
T13 648-656 DNA denotes PuF site
T14 673-700 DNA denotes positive regulatory element
T15 704-711 cell_type denotes B cells
T16 802-828 DNA denotes normal silent c-myc allele
T17 858-864 protein denotes Nm23H2
T18 921-933 DNA denotes c-myc allele
T19 937-961 cell_line denotes Burkitt's lymphoma cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-109 Sentence denotes The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma.
S2 110-229 Sentence denotes We have identified an in vivo footprint over the PuF site on the translocated c-myc allele in Burkitt's lymphoma cells.
S3 230-292 Sentence denotes The PuF site on the silent normal c-myc allele was unoccupied.
S4 293-544 Sentence denotes We demonstrated by electrophoretic mobility shift assay, electrophoretic mobility shift assay with antibody, UV cross-linking followed by SDS-gel electrophoresis, and Western analysis that Nm23H2 in B cell nuclear extracts bound to the c-myc PuF site.
S5 545-763 Sentence denotes Transfection experiments with c-myc promoter constructs in both DHL-9 and Raji cells revealed that the PuF site functioned as a positive regulatory element in B cells with a drop in activity with mutation of this site.
S6 764-962 Sentence denotes Access to this site is blocked in the normal silent c-myc allele; these data suggest that the Nm23H2 protein is involved in deregulation of the translocated c-myc allele in Burkitt's lymphoma cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-24 NP denotes The transcription factor
C2 26-32 NP denotes Nm23H2
C3 57-108 NP denotes the translocated c-myc allele in Burkitt's lymphoma
C4 155-167 NP denotes the PuF site
C5 171-228 NP denotes the translocated c-myc allele in Burkitt's lymphoma cells
C6 230-242 NP denotes The PuF site
C7 246-276 NP denotes the silent normal c-myc allele
C8 482-488 NP denotes Nm23H2
C9 525-543 NP denotes the c-myc PuF site
C10 644-656 NP denotes the PuF site
C11 753-762 NP denotes this site
C12 774-783 NP denotes this site
C13 798-828 NP denotes the normal silent c-myc allele
C14 904-961 NP denotes the translocated c-myc allele in Burkitt's lymphoma cells
R1 C2 C1 coref-appos Nm23H2,The transcription factor
R2 C5 C3 coref-ident the translocated c-myc allele in Burkitt's lymphoma cells,the translocated c-myc allele in Burkitt's lymphoma
R3 C6 C4 coref-ident The PuF site,the PuF site
R4 C8 C2 coref-ident Nm23H2,Nm23H2
R5 C9 C6 coref-ident the c-myc PuF site,The PuF site
R6 C10 C9 coref-ident the PuF site,the c-myc PuF site
R7 C11 C10 coref-ident this site,the PuF site
R8 C12 C11 coref-ident this site,this site
R9 C13 C7 coref-ident the normal silent c-myc allele,the silent normal c-myc allele
R10 C14 C5 coref-ident the translocated c-myc allele in Burkitt's lymphoma cells,the translocated c-myc allele in Burkitt's lymphoma cells

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 4-24 protein_family_or_group denotes transcription factor
T2 26-32 protein_molecule denotes Nm23H2
T3 74-86 DNA_domain_or_region denotes c-myc allele
T4 90-108 other_name denotes Burkitt's lymphoma
T5 132-149 other_name denotes in vivo footprint
T6 159-167 DNA_domain_or_region denotes PuF site
T7 188-200 DNA_domain_or_region denotes c-myc allele
T8 204-222 other_name denotes Burkitt's lymphoma
T9 234-242 DNA_domain_or_region denotes PuF site
T10 250-263 DNA_domain_or_region denotes silent normal
T11 264-276 DNA_domain_or_region denotes c-myc allele
T12 312-348 other_name denotes electrophoretic mobility shift assay
T13 350-386 other_name denotes electrophoretic mobility shift assay
T14 402-418 other_name denotes UV cross-linking
T15 431-454 other_name denotes SDS-gel electrophoresis
T16 460-476 other_name denotes Western analysis
T17 482-488 protein_molecule denotes Nm23H2
T18 492-515 cell_component denotes B cell nuclear extracts
T19 535-543 DNA_domain_or_region denotes PuF site
T20 575-589 DNA_domain_or_region denotes c-myc promoter
T21 609-614 cell_line denotes DHL-9
T22 619-629 cell_line denotes Raji cells
T23 648-656 DNA_domain_or_region denotes PuF site
T24 673-700 DNA_family_or_group denotes positive regulatory element
T25 704-711 cell_type denotes B cells
T26 802-815 DNA_domain_or_region denotes normal silent
T27 816-828 DNA_domain_or_region denotes c-myc allele
T28 858-864 protein_molecule denotes Nm23H2
T29 921-933 DNA_domain_or_region denotes c-myc allele
T30 937-955 other_name denotes Burkitt's lymphoma

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 90-108 Disease denotes Burkitt's lymphoma http://purl.obolibrary.org/obo/MONDO_0007243
T2 204-222 Disease denotes Burkitt's lymphoma http://purl.obolibrary.org/obo/MONDO_0007243
T3 937-955 Disease denotes Burkitt's lymphoma http://purl.obolibrary.org/obo/MONDO_0007243

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 492-498 Body_part denotes B cell http://purl.obolibrary.org/obo/CL_0000236

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 90-108 Phenotype denotes Burkitt's lymphoma HP:0030080
T2 204-222 Phenotype denotes Burkitt's lymphoma HP:0030080
T3 937-955 Phenotype denotes Burkitt's lymphoma HP:0030080

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 492-498 Cell denotes B cell http://purl.obolibrary.org/obo/CL:0000236
T2 704-711 Cell denotes B cells http://purl.obolibrary.org/obo/CL:0000236