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PubMed:7763041 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 1757-1760 gene:7157 denotes p53
T1 1908-1921 disease:C0006142 denotes breast cancer
T2 1757-1760 gene:7157 denotes p53
T3 1908-1921 disease:C0678222 denotes breast cancer
R1 T0 T1 associated_with p53,breast cancer
R2 T2 T3 associated_with p53,breast cancer

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 48-54 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T2 344-350 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T3 517-523 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T4 1908-1914 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T5 444-449 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T6 444-454 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2612 7-10 gene:7157 denotes p53
T2613 48-61 disease:C0006142 denotes breast cancer
R1 T2612 T2613 associated_with p53,breast cancer
R2 T2612 T2613 associated_with p53,breast cancer

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-122 Sentence denotes Mutant p53 expression and DNA analysis in human breast cancer comparison with conventional clinicopathological parameters.
TextSentencer_T2 123-235 Sentence denotes Scientific research evaluates the prognostic importance of 53 expression and DNA flow cytometry controversially.
TextSentencer_T3 236-510 Sentence denotes To evaluate the prognostic relevance of mutant p53 protein overexpression and DNA flow cytometry in primary breast cancer we correlated these factors with the common prognostic parameters such as tumor size, lymph node status, grading, menopausal status and receptor status.
TextSentencer_T4 511-611 Sentence denotes Human breast cancer specimens from 180 previously untreated patients were collected and deep frozen.
TextSentencer_T5 612-803 Sentence denotes On each specimen DNA-analysis by Geohde's technique (Partec PAS II) and immunohistochemical evaluation of mutant p53 protein (PAb 1801 and 240, Novocastra Lab., Great Britain) were performed.
TextSentencer_T6 804-918 Sentence denotes Besides TNM- and histological classification, estrogen (ER)- and progesterone (PgR) receptor content was recorded.
TextSentencer_T7 919-995 Sentence denotes Overexpression of mutant p53 protein was found in 34 (19%) of all specimens.
TextSentencer_T8 996-1214 Sentence denotes All these 34 tumors were aneuploid (p = 0.007), 86% of them were receptor negative (p 0.0001), 79% had a high tumor grade (p 0.0001), 73% a high S-phase-fraction (SPF) (p = 0.045) and 53% were premenopausal (p 0.0001).
TextSentencer_T9 1215-1294 Sentence denotes Tumor size and node status did not correlate significantly with p53 expression.
TextSentencer_T10 1295-1339 Sentence denotes 27 (15%) out of 180 carcinomas were diploid.
TextSentencer_T11 1340-1558 Sentence denotes There was a significant correlation between ploidy and the tumor grade (p = 0.003) and SPF (p 0.0001), but not correlation between ploidy and tumor size (p = 0.21), node status (p = 0.33) or receptor status (p = 0.18).
TextSentencer_T12 1559-1749 Sentence denotes A low SPF was predominantly found in tumors less than 2 cm in diameter (p 0.0001); no significant correlation was found between SPF, receptor status, tumor grade, node and menopausal status.
TextSentencer_T13 1750-1931 Sentence denotes Mutant p53 protein expression and DNA analysis in combination with common prognostic parameters might help to detect prognostically unfavourable subgroups of breast cancer patients.
T1 0-122 Sentence denotes Mutant p53 expression and DNA analysis in human breast cancer comparison with conventional clinicopathological parameters.
T2 123-235 Sentence denotes Scientific research evaluates the prognostic importance of 53 expression and DNA flow cytometry controversially.
T3 236-510 Sentence denotes To evaluate the prognostic relevance of mutant p53 protein overexpression and DNA flow cytometry in primary breast cancer we correlated these factors with the common prognostic parameters such as tumor size, lymph node status, grading, menopausal status and receptor status.
T4 511-611 Sentence denotes Human breast cancer specimens from 180 previously untreated patients were collected and deep frozen.
T5 612-803 Sentence denotes On each specimen DNA-analysis by Geohde's technique (Partec PAS II) and immunohistochemical evaluation of mutant p53 protein (PAb 1801 and 240, Novocastra Lab., Great Britain) were performed.
T6 804-918 Sentence denotes Besides TNM- and histological classification, estrogen (ER)- and progesterone (PgR) receptor content was recorded.
T7 919-995 Sentence denotes Overexpression of mutant p53 protein was found in 34 (19%) of all specimens.
T8 996-1214 Sentence denotes All these 34 tumors were aneuploid (p = 0.007), 86% of them were receptor negative (p 0.0001), 79% had a high tumor grade (p 0.0001), 73% a high S-phase-fraction (SPF) (p = 0.045) and 53% were premenopausal (p 0.0001).
T9 1215-1294 Sentence denotes Tumor size and node status did not correlate significantly with p53 expression.
T10 1295-1339 Sentence denotes 27 (15%) out of 180 carcinomas were diploid.
T11 1340-1558 Sentence denotes There was a significant correlation between ploidy and the tumor grade (p = 0.003) and SPF (p 0.0001), but not correlation between ploidy and tumor size (p = 0.21), node status (p = 0.33) or receptor status (p = 0.18).
T12 1559-1749 Sentence denotes A low SPF was predominantly found in tumors less than 2 cm in diameter (p 0.0001); no significant correlation was found between SPF, receptor status, tumor grade, node and menopausal status.
T13 1750-1931 Sentence denotes Mutant p53 protein expression and DNA analysis in combination with common prognostic parameters might help to detect prognostically unfavourable subgroups of breast cancer patients.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 48-54 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T2 344-350 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T3 517-523 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T4 1908-1914 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T5 444-449 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T6 444-454 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node