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sentences

Id Subject Object Predicate Lexical cue
T1 0-89 Sentence denotes Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation.
T2 90-300 Sentence denotes T cells express multiple isotypes of protein kinase C (PKC) and although it is well accepted that PKCs have an important role in T cell activation, little is known about the function of individual PKC isotypes.
T3 301-516 Sentence denotes To address this issue, mutationally active PKC-alpha, -epsilon, or -zeta have been transfected into T cells and the consequences for T cell activation determined. p21ras plays an essential role in T cell activation.
T4 517-638 Sentence denotes Accordingly, the effects of the constitutively active PKCs were compared to the effects of mutationally activated p21ras.
T5 639-817 Sentence denotes The data indicate that PKC-epsilon and, to a lesser extent PKC-alpha but not -zeta, can regulate the transcription factors AP-1 and nuclear factor of activated T cells (NF-AT-1).
T6 818-966 Sentence denotes The ability of PKC-epsilon to induce transactivation of NF-AT-1 and AP-1 was similar to the stimulatory effect of a constitutively activated p21ras.
T7 967-1054 Sentence denotes PKC-epsilon, but not PKC-alpha nor activated p21ras, was able to induce NF-KB activity.
T8 1055-1176 Sentence denotes Phorbol esters induce expression of CD69 whereas none of the activated PKC isotypes tested were able to have this effect.
T9 1177-1238 Sentence denotes Activated Src and p21ras were able to induce CD69 expression.
T10 1239-1320 Sentence denotes These results indicate selective functions for different PKC isotypes in T cells.
T11 1321-1511 Sentence denotes Moreover, the data comparing the effects of activated Ras and PKC mutants suggest that PKC-alpha, p21ras, and PKC-epsilon are not positioned linearly on a single signal transduction pathway.
T1 0-89 Sentence denotes Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation.
T2 90-300 Sentence denotes T cells express multiple isotypes of protein kinase C (PKC) and although it is well accepted that PKCs have an important role in T cell activation, little is known about the function of individual PKC isotypes.
T3 301-516 Sentence denotes To address this issue, mutationally active PKC-alpha, -epsilon, or -zeta have been transfected into T cells and the consequences for T cell activation determined. p21ras plays an essential role in T cell activation.
T4 517-638 Sentence denotes Accordingly, the effects of the constitutively active PKCs were compared to the effects of mutationally activated p21ras.
T5 639-817 Sentence denotes The data indicate that PKC-epsilon and, to a lesser extent PKC-alpha but not -zeta, can regulate the transcription factors AP-1 and nuclear factor of activated T cells (NF-AT-1).
T6 818-966 Sentence denotes The ability of PKC-epsilon to induce transactivation of NF-AT-1 and AP-1 was similar to the stimulatory effect of a constitutively activated p21ras.
T7 967-1054 Sentence denotes PKC-epsilon, but not PKC-alpha nor activated p21ras, was able to induce NF-KB activity.
T8 1055-1176 Sentence denotes Phorbol esters induce expression of CD69 whereas none of the activated PKC isotypes tested were able to have this effect.
T9 1177-1238 Sentence denotes Activated Src and p21ras were able to induce CD69 expression.
T10 1239-1320 Sentence denotes These results indicate selective functions for different PKC isotypes in T cells.
T11 1321-1511 Sentence denotes Moreover, the data comparing the effects of activated Ras and PKC mutants suggest that PKC-alpha, p21ras, and PKC-epsilon are not positioned linearly on a single signal transduction pathway.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 24-67 protein denotes protein kinase C-alpha, -epsilon, and -zeta
T2 90-97 cell_type denotes T cells
T3 127-143 protein denotes protein kinase C
T4 145-148 protein denotes PKC
T5 188-192 protein denotes PKCs
T6 287-299 protein denotes PKC isotypes
T7 344-373 protein denotes PKC-alpha, -epsilon, or -zeta
T8 401-408 cell_type denotes T cells
T9 464-470 protein denotes p21ras
T10 549-575 protein denotes constitutively active PKCs
T11 631-637 protein denotes p21ras
T12 662-673 protein denotes PKC-epsilon
T13 698-707 protein denotes PKC-alpha
T14 716-721 protein denotes -zeta
T15 740-761 protein denotes transcription factors
T16 762-766 protein denotes AP-1
T17 779-806 protein denotes factor of activated T cells
T18 808-815 protein denotes NF-AT-1
T19 833-844 protein denotes PKC-epsilon
T20 874-881 protein denotes NF-AT-1
T21 886-890 protein denotes AP-1
T22 934-965 protein denotes constitutively activated p21ras
T23 967-978 protein denotes PKC-epsilon
T24 988-997 protein denotes PKC-alpha
T25 1012-1018 protein denotes p21ras
T26 1039-1044 protein denotes NF-KB
T27 1091-1095 protein denotes CD69
T28 1116-1138 protein denotes activated PKC isotypes
T29 1187-1190 protein denotes Src
T30 1195-1201 protein denotes p21ras
T31 1222-1226 protein denotes CD69
T32 1296-1308 protein denotes PKC isotypes
T33 1312-1319 cell_type denotes T cells
T34 1365-1378 protein denotes activated Ras
T35 1383-1394 protein denotes PKC mutants
T36 1408-1417 protein denotes PKC-alpha
T37 1419-1425 protein denotes p21ras
T38 1431-1442 protein denotes PKC-epsilon

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 71-88 NP denotes T cell activation
C2 90-97 NP denotes T cells
C3 127-149 NP denotes protein kinase C (PKC)
C4 188-192 NP denotes PKCs
C5 219-236 NP denotes T cell activation
C6 324-373 NP denotes mutationally active PKC-alpha, -epsilon, or -zeta
C7 401-408 NP denotes T cells
C8 434-451 NP denotes T cell activation
C9 464-470 NP denotes p21ras
C10 498-515 NP denotes T cell activation
C11 545-575 NP denotes the constitutively active PKCs
C13 608-637 NP denotes mutationally activated p21ras
C12 593-637 NP denotes the effects of mutationally activated p21ras
C14 662-673 NP denotes PKC-epsilon
C15 736-816 NP denotes the transcription factors AP-1 and nuclear factor of activated T cells (NF-AT-1)
C16 833-844 NP denotes PKC-epsilon
C17 874-890 NP denotes NF-AT-1 and AP-1
C19 932-965 NP denotes a constitutively activated p21ras
C18 906-965 NP denotes the stimulatory effect of a constitutively activated p21ras
C20 967-978 NP denotes PKC-epsilon
C21 988-997 NP denotes PKC-alpha
C22 1002-1018 NP denotes activated p21ras
C23 1077-1095 NP denotes expression of CD69
C24 1112-1145 NP denotes the activated PKC isotypes tested
C25 1222-1237 NP denotes CD69 expression
C26 1312-1319 NP denotes T cells
C27 1408-1417 NP denotes PKC-alpha
C28 1419-1425 NP denotes p21ras
C29 1431-1442 NP denotes PKC-epsilon
R1 C4 C3 coref-ident PKCs,protein kinase C (PKC)
R2 C5 C1 coref-ident T cell activation,T cell activation
R3 C7 C2 coref-ident T cells,T cells
R4 C8 C5 coref-ident T cell activation,T cell activation
R5 C10 C8 coref-ident T cell activation,T cell activation
R6 C11 C6 coref-ident the constitutively active PKCs,"mutationally active PKC-alpha, -epsilon, or -zeta"
R7 C16 C14 coref-ident PKC-epsilon,PKC-epsilon
R8 C17 C15 coref-ident NF-AT-1 and AP-1,the transcription factors AP-1 and nuclear factor of activated T cells (NF-AT-1)
R9 C19 C13 coref-ident a constitutively activated p21ras,mutationally activated p21ras
R10 C18 C12 coref-ident the stimulatory effect of a constitutively activated p21ras,the effects of mutationally activated p21ras
R11 C20 C16 coref-ident PKC-epsilon,PKC-epsilon
R12 C22 C19 coref-ident activated p21ras,a constitutively activated p21ras
R13 C24 C11 coref-ident the activated PKC isotypes tested,the constitutively active PKCs
R14 C25 C23 coref-ident CD69 expression,expression of CD69
R15 C26 C7 coref-ident T cells,T cells
R16 C27 C21 coref-ident PKC-alpha,PKC-alpha
R17 C28 C9 coref-ident p21ras,p21ras
R18 C29 C20 coref-ident PKC-epsilon,PKC-epsilon

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-89 Sentence denotes Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation.
S2 90-300 Sentence denotes T cells express multiple isotypes of protein kinase C (PKC) and although it is well accepted that PKCs have an important role in T cell activation, little is known about the function of individual PKC isotypes.
S3 301-463 Sentence denotes To address this issue, mutationally active PKC-alpha, -epsilon, or -zeta have been transfected into T cells and the consequences for T cell activation determined.
S4 464-516 Sentence denotes p21ras plays an essential role in T cell activation.
S5 517-638 Sentence denotes Accordingly, the effects of the constitutively active PKCs were compared to the effects of mutationally activated p21ras.
S6 639-817 Sentence denotes The data indicate that PKC-epsilon and, to a lesser extent PKC-alpha but not -zeta, can regulate the transcription factors AP-1 and nuclear factor of activated T cells (NF-AT-1).
S7 818-966 Sentence denotes The ability of PKC-epsilon to induce transactivation of NF-AT-1 and AP-1 was similar to the stimulatory effect of a constitutively activated p21ras.
S8 967-1054 Sentence denotes PKC-epsilon, but not PKC-alpha nor activated p21ras, was able to induce NF-KB activity.
S9 1055-1176 Sentence denotes Phorbol esters induce expression of CD69 whereas none of the activated PKC isotypes tested were able to have this effect.
S10 1177-1238 Sentence denotes Activated Src and p21ras were able to induce CD69 expression.
S11 1239-1320 Sentence denotes These results indicate selective functions for different PKC isotypes in T cells.
S12 1321-1511 Sentence denotes Moreover, the data comparing the effects of activated Ras and PKC mutants suggest that PKC-alpha, p21ras, and PKC-epsilon are not positioned linearly on a single signal transduction pathway.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 71-88 other_name denotes T cell activation
T2 90-97 cell_type denotes T cells
T3 127-143 protein_molecule denotes protein kinase C
T4 145-148 protein_molecule denotes PKC
T5 188-192 protein_molecule denotes PKCs
T6 219-236 other_name denotes T cell activation
T7 287-299 protein_family_or_group denotes PKC isotypes
T8 401-408 cell_type denotes T cells
T9 434-451 other_name denotes T cell activation
T10 464-470 protein_molecule denotes p21ras
T11 498-515 other_name denotes T cell activation
T12 549-575 protein_family_or_group denotes constitutively active PKCs
T13 631-637 protein_molecule denotes p21ras
T14 662-673 protein_molecule denotes PKC-epsilon
T15 698-707 protein_molecule denotes PKC-alpha
T16 716-721 protein_molecule denotes -zeta
T17 740-761 protein_family_or_group denotes transcription factors
T18 762-766 protein_molecule denotes AP-1
T19 779-798 protein_family_or_group denotes factor of activated
T20 799-806 cell_type denotes T cells
T21 808-815 protein_molecule denotes NF-AT-1
T22 833-844 protein_molecule denotes PKC-epsilon
T23 874-881 protein_molecule denotes NF-AT-1
T24 886-890 protein_molecule denotes AP-1
T25 934-958 protein_molecule denotes constitutively activated
T26 959-965 protein_molecule denotes p21ras
T27 967-978 protein_molecule denotes PKC-epsilon
T28 988-997 protein_molecule denotes PKC-alpha
T29 1012-1018 protein_molecule denotes p21ras
T30 1039-1044 protein_molecule denotes NF-KB
T31 1055-1069 other_organic_compound denotes Phorbol esters
T32 1091-1095 protein_molecule denotes CD69
T33 1116-1125 protein_family_or_group denotes activated
T34 1126-1138 protein_family_or_group denotes PKC isotypes
T35 1187-1190 protein_family_or_group denotes Src
T36 1195-1201 protein_molecule denotes p21ras
T37 1222-1226 protein_molecule denotes CD69
T38 1296-1308 protein_family_or_group denotes PKC isotypes
T39 1312-1319 cell_type denotes T cells
T40 1365-1378 protein_family_or_group denotes activated Ras
T41 1383-1394 protein_family_or_group denotes PKC mutants
T42 1408-1417 protein_molecule denotes PKC-alpha
T43 1419-1425 protein_molecule denotes p21ras
T44 1431-1442 protein_molecule denotes PKC-epsilon
T45 1476-1510 other_name denotes single signal transduction pathway

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-89 Sentence denotes Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation.
T2 90-300 Sentence denotes T cells express multiple isotypes of protein kinase C (PKC) and although it is well accepted that PKCs have an important role in T cell activation, little is known about the function of individual PKC isotypes.
T3 301-516 Sentence denotes To address this issue, mutationally active PKC-alpha, -epsilon, or -zeta have been transfected into T cells and the consequences for T cell activation determined. p21ras plays an essential role in T cell activation.
T4 517-638 Sentence denotes Accordingly, the effects of the constitutively active PKCs were compared to the effects of mutationally activated p21ras.
T5 639-817 Sentence denotes The data indicate that PKC-epsilon and, to a lesser extent PKC-alpha but not -zeta, can regulate the transcription factors AP-1 and nuclear factor of activated T cells (NF-AT-1).
T6 818-966 Sentence denotes The ability of PKC-epsilon to induce transactivation of NF-AT-1 and AP-1 was similar to the stimulatory effect of a constitutively activated p21ras.
T7 967-1054 Sentence denotes PKC-epsilon, but not PKC-alpha nor activated p21ras, was able to induce NF-KB activity.
T8 1055-1176 Sentence denotes Phorbol esters induce expression of CD69 whereas none of the activated PKC isotypes tested were able to have this effect.
T9 1177-1238 Sentence denotes Activated Src and p21ras were able to induce CD69 expression.
T10 1239-1320 Sentence denotes These results indicate selective functions for different PKC isotypes in T cells.
T11 1321-1511 Sentence denotes Moreover, the data comparing the effects of activated Ras and PKC mutants suggest that PKC-alpha, p21ras, and PKC-epsilon are not positioned linearly on a single signal transduction pathway.

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 71-77 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T2 219-225 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T3 434-440 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T4 498-504 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 49-56 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T2 71-77 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T3 90-97 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T4 219-225 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T5 356-363 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T6 401-408 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T7 434-440 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T8 498-504 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T9 666-673 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T10 799-806 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T11 837-844 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T12 971-978 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T13 1312-1319 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T14 1435-1442 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025