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PubMed:7685021 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-56 Sentence denotes CD36 is a receptor for oxidized low density lipoprotein.
T2 57-302 Sentence denotes The oxidation of low density lipoprotein (LDL) in the arterial wall is thought to contribute to human atherosclerotic lesion formation, in part by the high affinity uptake of oxidized LDL (OxLDL) by macrophages, resulting in foam cell formation.
T3 303-394 Sentence denotes We have utilized cloning by expression to identify CD36 as a macrophage receptor for OxLDL.
T4 395-547 Sentence denotes Transfection of a CD36 clone into 293 cells results in the specific and high affinity binding of OxLDL, followed by its internalization and degradation.
T5 548-657 Sentence denotes An anti-CD36 antibody blocks 50% of the binding of OxLDL to platelets and to human macrophage-like THP cells.
T6 658-933 Sentence denotes Furthermore, like mouse macrophages, 293 cells expressing CD36 recognize LDL which has been oxidized only 4 h, whereas more extensive oxidation of the LDL is required for recognition by the other known OxLDL receptors, the acetylated LDL (AcLDL) receptor and Fc gamma RII-B2.
T7 934-1082 Sentence denotes CD36 may play a role in scavenging LDL modified by oxidation and may mediate effects of OxLDL on monocytes and platelets in atherosclerotic lesions.
T1 0-56 Sentence denotes CD36 is a receptor for oxidized low density lipoprotein.
T2 57-302 Sentence denotes The oxidation of low density lipoprotein (LDL) in the arterial wall is thought to contribute to human atherosclerotic lesion formation, in part by the high affinity uptake of oxidized LDL (OxLDL) by macrophages, resulting in foam cell formation.
T3 303-394 Sentence denotes We have utilized cloning by expression to identify CD36 as a macrophage receptor for OxLDL.
T4 395-547 Sentence denotes Transfection of a CD36 clone into 293 cells results in the specific and high affinity binding of OxLDL, followed by its internalization and degradation.
T5 548-657 Sentence denotes An anti-CD36 antibody blocks 50% of the binding of OxLDL to platelets and to human macrophage-like THP cells.
T6 658-933 Sentence denotes Furthermore, like mouse macrophages, 293 cells expressing CD36 recognize LDL which has been oxidized only 4 h, whereas more extensive oxidation of the LDL is required for recognition by the other known OxLDL receptors, the acetylated LDL (AcLDL) receptor and Fc gamma RII-B2.
T7 934-1082 Sentence denotes CD36 may play a role in scavenging LDL modified by oxidation and may mediate effects of OxLDL on monocytes and platelets in atherosclerotic lesions.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 111-119 http://purl.obolibrary.org/obo/MAT_0000034 denotes arterial

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 111-119 Body_part denotes arterial http://purl.obolibrary.org/obo/MAT_0000034

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 159-181 Phenotype denotes atherosclerotic lesion HP:0031678
T2 282-291 Phenotype denotes foam cell HP:0003651
T3 1058-1081 Phenotype denotes atherosclerotic lesions HP:0031678

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 153-158 OrganismTaxon denotes human 9606
T2 625-630 OrganismTaxon denotes human 9606
T3 676-681 OrganismTaxon denotes mouse 10088|10090

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 111-124 Body_part denotes arterial wall http://purl.obolibrary.org/obo/UBERON_0000415
T2 256-267 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T3 364-374 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T4 608-617 Body_part denotes platelets http://purl.obolibrary.org/obo/CL_0000233
T5 631-641 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T6 682-693 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T7 1031-1040 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T9 1045-1054 Body_part denotes platelets http://purl.obolibrary.org/obo/CL_0000233

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 256-267 Cell denotes macrophages http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T3 282-291 Cell denotes foam cell http://purl.obolibrary.org/obo/CL:0000891
T4 364-374 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T6 608-617 Cell denotes platelets http://purl.obolibrary.org/obo/CL:0000233
T7 631-641 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T9 682-693 Cell denotes macrophages http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T11 1031-1040 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T13 1045-1054 Cell denotes platelets http://purl.obolibrary.org/obo/CL:0000233