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sentences

Id Subject Object Predicate Lexical cue
T1 0-86 Sentence denotes Different dimerization activities of alpha and beta thyroid hormone receptor isoforms.
T2 87-212 Sentence denotes Thyroid hormone receptors (TR) are ligand-dependent transcription factors that are encoded as multiple isoforms on two genes.
T3 213-410 Sentence denotes To date, no functional differences have been shown between the TR isoforms; however, the maintenance of alpha and beta genes during vertebrate evolution argues that functional differences do exist.
T4 411-490 Sentence denotes We have localized a TR-binding site in the rabbit beta-myosin heavy chain gene.
T5 491-706 Sentence denotes This site and TR-binding sites in the chicken lysozyme and rat alpha-glycoprotein hormone genes were used to compare the DNA-binding activities of TR alpha and TR beta and the influence of auxiliary proteins (TRAP).
T6 707-813 Sentence denotes TR alpha formed alpha/alpha homodimers poorly, whereas TR beta formed beta/beta homodimers preferentially.
T7 814-1075 Sentence denotes This difference was not due to either a lower amount of TR alpha synthesized in the reticulocyte lysate or to an inability of the expressed TR alpha to form dimers, since both TR alpha and TR beta readily formed heterodimers with TRAP on these TR-binding sites.
T8 1076-1224 Sentence denotes Additionally, a TR alpha fragment containing the dimerization domains (TR alpha C291) blocks TR beta/TRAP complexes but not TR alpha/TRAP complexes.
T9 1225-1317 Sentence denotes This indicates that TR beta/TR alpha dimers form more readily than TR alpha/TR alpha dimers.
T10 1318-1481 Sentence denotes We conclude that on the binding sites examined, TR beta has a greater tendency to form homodimers than TR alpha, whereas both isoforms form heterodimers similarly.
T11 1482-1622 Sentence denotes The different homodimerization potentials of TR alpha and TR beta may underlie functional differences that affect thyroid hormone responses.
T1 0-86 Sentence denotes Different dimerization activities of alpha and beta thyroid hormone receptor isoforms.
T2 87-212 Sentence denotes Thyroid hormone receptors (TR) are ligand-dependent transcription factors that are encoded as multiple isoforms on two genes.
T3 213-410 Sentence denotes To date, no functional differences have been shown between the TR isoforms; however, the maintenance of alpha and beta genes during vertebrate evolution argues that functional differences do exist.
T4 411-490 Sentence denotes We have localized a TR-binding site in the rabbit beta-myosin heavy chain gene.
T5 491-706 Sentence denotes This site and TR-binding sites in the chicken lysozyme and rat alpha-glycoprotein hormone genes were used to compare the DNA-binding activities of TR alpha and TR beta and the influence of auxiliary proteins (TRAP).
T6 707-813 Sentence denotes TR alpha formed alpha/alpha homodimers poorly, whereas TR beta formed beta/beta homodimers preferentially.
T7 814-1075 Sentence denotes This difference was not due to either a lower amount of TR alpha synthesized in the reticulocyte lysate or to an inability of the expressed TR alpha to form dimers, since both TR alpha and TR beta readily formed heterodimers with TRAP on these TR-binding sites.
T8 1076-1224 Sentence denotes Additionally, a TR alpha fragment containing the dimerization domains (TR alpha C291) blocks TR beta/TRAP complexes but not TR alpha/TRAP complexes.
T9 1225-1317 Sentence denotes This indicates that TR beta/TR alpha dimers form more readily than TR alpha/TR alpha dimers.
T10 1318-1481 Sentence denotes We conclude that on the binding sites examined, TR beta has a greater tendency to form homodimers than TR alpha, whereas both isoforms form heterodimers similarly.
T11 1482-1622 Sentence denotes The different homodimerization potentials of TR alpha and TR beta may underlie functional differences that affect thyroid hormone responses.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 52-59 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T2 87-94 http://purl.obolibrary.org/obo/MAT_0000081 denotes Thyroid
T3 345-355 http://purl.obolibrary.org/obo/MAT_0000373 denotes vertebrate
T4 1596-1603 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 52-59 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T2 87-94 Body_part denotes Thyroid http://purl.obolibrary.org/obo/MAT_0000081
T3 345-355 Body_part denotes vertebrate http://purl.obolibrary.org/obo/MAT_0000373
T4 1596-1603 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 550-553 OrganismTaxon denotes rat 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 52-59 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T2 87-94 Body_part denotes Thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T3 898-910 Body_part denotes reticulocyte http://purl.obolibrary.org/obo/CL_0000558
T4 1596-1603 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 898-910 Cell denotes reticulocyte http://purl.obolibrary.org/obo/CL:0000558