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PubMed:7683574 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 358-391 gene:4507 denotes methylthioadenosine phosphorylase
T1 489-517 disease:C0023449 denotes acute lymphoblastic leukemia
T2 358-391 gene:4507 denotes methylthioadenosine phosphorylase
T3 489-517 disease:C1961102 denotes acute lymphoblastic leukemia
T4 358-391 gene:4507 denotes methylthioadenosine phosphorylase
T5 527-534 disease:C0017638 denotes gliomas
T6 393-397 gene:4507 denotes MTAP
T7 489-517 disease:C0023449 denotes acute lymphoblastic leukemia
T8 393-397 gene:4507 denotes MTAP
T9 527-534 disease:C0017638 denotes gliomas
T10 393-397 gene:4507 denotes MTAP
T11 489-517 disease:C1961102 denotes acute lymphoblastic leukemia
T12 606-609 gene:3439 denotes IFN
T13 665-677 disease:C0242379 denotes lung cancers
T14 606-609 gene:3447 denotes IFN
T15 665-677 disease:C0242379 denotes lung cancers
R1 T0 T1 associated_with methylthioadenosine phosphorylase,acute lymphoblastic leukemia
R2 T2 T3 associated_with methylthioadenosine phosphorylase,acute lymphoblastic leukemia
R3 T4 T5 associated_with methylthioadenosine phosphorylase,gliomas
R4 T6 T7 associated_with MTAP,acute lymphoblastic leukemia
R5 T8 T9 associated_with MTAP,gliomas
R6 T10 T11 associated_with MTAP,acute lymphoblastic leukemia
R7 T12 T13 associated_with IFN,lung cancers
R8 T14 T15 associated_with IFN,lung cancers

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7683574-2#74#107#gene4507 358-391 gene4507 denotes methylthioadenosine phosphorylase
7683574-2#109#113#gene4507 393-397 gene4507 denotes MTAP
7683574-2#243#250#diseaseC0017638 527-534 diseaseC0017638 denotes gliomas
74#107#gene4507243#250#diseaseC0017638 7683574-2#74#107#gene4507 7683574-2#243#250#diseaseC0017638 associated_with methylthioadenosine phosphorylase,gliomas
109#113#gene4507243#250#diseaseC0017638 7683574-2#109#113#gene4507 7683574-2#243#250#diseaseC0017638 associated_with MTAP,gliomas

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2591 358-391 gene:4507 denotes methylthioadenosine phosphorylase
T2592 489-517 disease:C0023449 denotes acute lymphoblastic leukemia
T2593 393-397 gene:4507 denotes MTAP
T2594 606-609 gene:3439 denotes IFN
T2595 665-677 disease:C0242379 denotes lung cancers
T2596 1082-1086 gene:4507 denotes MTAP
T2597 974-985 disease:C0242379 denotes lung cancer
R1 T2591 T2592 associated_with methylthioadenosine phosphorylase,acute lymphoblastic leukemia
R2 T2591 T2592 associated_with methylthioadenosine phosphorylase,acute lymphoblastic leukemia
R3 T2593 T2592 associated_with MTAP,acute lymphoblastic leukemia
R4 T2593 T2592 associated_with MTAP,acute lymphoblastic leukemia
R5 T2594 T2595 associated_with IFN,lung cancers
R6 T2594 T2595 associated_with IFN,lung cancers
R7 T2596 T2597 associated_with MTAP,lung cancer
R8 T2596 T2597 associated_with MTAP,lung cancer
R9 T2596 T2597 associated_with MTAP,lung cancer

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-106 Sentence denotes Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers.
TextSentencer_T2 107-283 Sentence denotes Cytogenetic analyses of non-small cell lung cancer have revealed deletions of the short arm of chromosome 9 with breakpoints at 9p11-pter in a significant proportion of tumors.
TextSentencer_T3 284-535 Sentence denotes Recent evidence suggests that homozygous loss of the interferon (IFN) and methylthioadenosine phosphorylase (MTAP) genes located on 9p and a tumor suppressor gene closely linked to them is associated with acute lymphoblastic leukemia and with gliomas.
TextSentencer_T4 536-696 Sentence denotes We have observed alterations of DNA sequences on 9p which include the IFN genes at a significant frequency in all types of human lung cancers (20 of 56 or 36%).
TextSentencer_T5 697-843 Sentence denotes The genetic alterations observed include homozygous or hemizygous deletions of the IFN genes as well as rearrangement of contiguous DNA sequences.
TextSentencer_T6 844-949 Sentence denotes In addition to these genomic alterations, 10 of 22 (45%) cell lines examined lacked MTAP enzyme activity.
TextSentencer_T7 950-1093 Sentence denotes Overall, 24 of 56 (43%) lung cancer cell lines examined had hemizygous or homozygous loss of DNA sequences which include the IFN or MTAP genes.
TextSentencer_T8 1094-1264 Sentence denotes These findings suggest that the putative tumor suppressor gene at this locus contributes to the malignant process in lung cancers, as well as other types of human cancer.
T1 0-106 Sentence denotes Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers.
T2 107-283 Sentence denotes Cytogenetic analyses of non-small cell lung cancer have revealed deletions of the short arm of chromosome 9 with breakpoints at 9p11-pter in a significant proportion of tumors.
T3 284-535 Sentence denotes Recent evidence suggests that homozygous loss of the interferon (IFN) and methylthioadenosine phosphorylase (MTAP) genes located on 9p and a tumor suppressor gene closely linked to them is associated with acute lymphoblastic leukemia and with gliomas.
T4 536-696 Sentence denotes We have observed alterations of DNA sequences on 9p which include the IFN genes at a significant frequency in all types of human lung cancers (20 of 56 or 36%).
T5 697-843 Sentence denotes The genetic alterations observed include homozygous or hemizygous deletions of the IFN genes as well as rearrangement of contiguous DNA sequences.
T6 844-949 Sentence denotes In addition to these genomic alterations, 10 of 22 (45%) cell lines examined lacked MTAP enzyme activity.
T7 950-1093 Sentence denotes Overall, 24 of 56 (43%) lung cancer cell lines examined had hemizygous or homozygous loss of DNA sequences which include the IFN or MTAP genes.
T8 1094-1264 Sentence denotes These findings suggest that the putative tumor suppressor gene at this locus contributes to the malignant process in lung cancers, as well as other types of human cancer.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 93-97 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 146-150 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T3 665-669 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T4 974-978 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T5 1211-1215 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T6 195-198 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 93-97 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 146-150 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T3 665-669 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T4 974-978 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T5 1211-1215 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T6 195-198 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm