> top > docs > PubMed:7678779 > annotations

PubMed:7678779 JSONTXT

Annnotations TAB JSON ListView MergeView

DisGeNET

Id Subject Object Predicate Lexical cue
T0 194-197 gene:4616 denotes MyD
T1 360-381 disease:C2242826 denotes myeloblastic leukemia
T2 152-192 gene:4616 denotes myeloid differentiation primary response
T3 360-381 disease:C0023479 denotes myeloblastic leukemia
T4 194-197 gene:4616 denotes MyD
T5 360-381 disease:C0023479 denotes myeloblastic leukemia
T6 152-192 gene:4616 denotes myeloid differentiation primary response
T7 360-381 disease:C2242826 denotes myeloblastic leukemia
T8 712-717 gene:1958 denotes Egr-1
T9 802-818 disease:C0023470 denotes myeloid leukemia
R1 T0 T1 associated_with MyD,myeloblastic leukemia
R2 T2 T3 associated_with myeloid differentiation primary response,myeloblastic leukemia
R3 T4 T5 associated_with MyD,myeloblastic leukemia
R4 T6 T7 associated_with myeloid differentiation primary response,myeloblastic leukemia
R5 T8 T9 associated_with Egr-1,myeloid leukemia

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 4-36 protein denotes zinc finger transcription factor
T2 37-42 protein denotes Egr-1
T3 100-118 cell_type denotes macrophage lineage
T4 137-148 DNA denotes cDNA clones
T5 152-204 DNA denotes myeloid differentiation primary response (MyD) genes
T6 317-327 cell_type denotes macrophage
T7 331-350 cell_type denotes granulocyte lineage
T8 360-393 cell_line denotes myeloblastic leukemia HL-60 cells
T9 399-409 DNA denotes cDNA clone
T10 493-498 protein denotes Egr-1
T11 502-534 protein denotes zinc finger transcription factor
T12 540-550 DNA denotes Egr-1 gene
T13 598-609 cell_line denotes HL-60 cells
T14 625-630 cell_line denotes U-937
T15 635-643 cell_line denotes M1 cells
T16 712-717 protein denotes Egr-1
T17 802-829 cell_line denotes myeloid leukemia cell lines
T18 841-852 cell_type denotes myeloblasts
T19 854-865 cell_line denotes HL-60 cells
T20 895-910 DNA denotes Egr-1 transgene
T21 912-922 DNA denotes HL-60Egr-1
T22 945-955 cell_type denotes macrophage
T23 965-976 cell_type denotes granulocyte
T24 1042-1047 protein denotes Egr-1
T25 1098-1109 cell_type denotes myeloblasts
T26 1120-1138 cell_type denotes macrophage lineage

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7678779-1#32#72#gene4616 152-192 gene4616 denotes myeloid differentiation primary response
7678779-1#74#77#gene4616 194-197 gene4616 denotes MyD
7678779-1#240#261#diseaseC0023479 360-381 diseaseC0023479 denotes myeloblastic leukemia
7678779-4#0#5#gene1958 712-717 gene1958 denotes Egr-1
7678779-4#90#106#diseaseC0023470 802-818 diseaseC0023470 denotes myeloid leukemia
32#72#gene4616240#261#diseaseC0023479 7678779-1#32#72#gene4616 7678779-1#240#261#diseaseC0023479 associated_with myeloid differentiation primary response,myeloblastic leukemia
74#77#gene4616240#261#diseaseC0023479 7678779-1#74#77#gene4616 7678779-1#240#261#diseaseC0023479 associated_with MyD,myeloblastic leukemia
0#5#gene195890#106#diseaseC0023470 7678779-4#0#5#gene1958 7678779-4#90#106#diseaseC0023470 associated_with Egr-1,myeloid leukemia

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-42 NP denotes The zinc finger transcription factor Egr-1
C2 74-118 NP denotes differentiation along the macrophage lineage
C3 137-204 NP denotes cDNA clones of myeloid differentiation primary response (MyD) genes
C4 354-393 NP denotes human myeloblastic leukemia HL-60 cells
C5 395-436 NP denotes One cDNA clone of a primary response gene
C6 453-479 NP denotes macrophage differentiation
C7 493-498 NP denotes Egr-1
C8 500-534 NP denotes a zinc finger transcription factor
C9 540-545 NP denotes Egr-1
C10 598-609 NP denotes HL-60 cells
C11 625-643 NP denotes U-937 and M1 cells
C12 645-659 NP denotes the latter two
C13 684-710 NP denotes macrophage differentiation
C14 712-717 NP denotes Egr-1
C15 767-793 NP denotes macrophage differentiation
C16 834-852 NP denotes normal myeloblasts
C17 854-865 NP denotes HL-60 cells
C18 895-900 NP denotes Egr-1
C19 1042-1047 NP denotes Egr-1
C21 1098-1109 NP denotes myeloblasts
C20 1079-1138 NP denotes differentiation of myeloblasts along the macrophage lineage
R1 C5 C3 coref-other One cDNA clone of a primary response gene,cDNA clones of myeloid differentiation primary response (MyD) genes
R2 C6 C2 coref-other macrophage differentiation,differentiation along the macrophage lineage
R3 C7 C1 coref-ident Egr-1,The zinc finger transcription factor Egr-1
R4 C8 C7 coref-appos a zinc finger transcription factor,Egr-1
R5 C9 C7 coref-ident Egr-1,Egr-1
R6 C10 C4 coref-other HL-60 cells,human myeloblastic leukemia HL-60 cells
R7 C12 C11 coref-ident the latter two,U-937 and M1 cells
R8 C13 C6 coref-ident macrophage differentiation,macrophage differentiation
R9 C14 C9 coref-ident Egr-1,Egr-1
R10 C15 C13 coref-ident macrophage differentiation,macrophage differentiation
R11 C17 C10 coref-ident HL-60 cells,HL-60 cells
R12 C18 C14 coref-ident Egr-1,Egr-1
R13 C19 C18 coref-ident Egr-1,Egr-1
R14 C21 C16 coref-other myeloblasts,normal myeloblasts
R15 C20 C15 coref-other differentiation of myeloblasts along the macrophage lineage,macrophage differentiation

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-119 Sentence denotes The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage.
S2 120-394 Sentence denotes We have isolated cDNA clones of myeloid differentiation primary response (MyD) genes, activated in the absence of de novo protein synthesis following induction for differentiation along either the macrophage or granulocyte lineage in human myeloblastic leukemia HL-60 cells.
S3 395-535 Sentence denotes One cDNA clone of a primary response gene, expressed upon macrophage differentiation, encoded for Egr-1, a zinc finger transcription factor.
S4 536-711 Sentence denotes The Egr-1 gene was observed to be transcriptionally silent in HL-60 cells, but active in U-937 and M1 cells, the latter two being predetermined for macrophage differentiation.
S5 712-853 Sentence denotes Egr-1 antisense oligomers in the culture media blocked macrophage differentiation in both myeloid leukemia cell lines and normal myeloblasts.
S6 854-994 Sentence denotes HL-60 cells constitutively expressing an Egr-1 transgene (HL-60Egr-1) could be induced for macrophage, but not granulocyte, differentiation.
S7 995-1139 Sentence denotes These observations indicate that expression of Egr-1 is essential for and restricts differentiation of myeloblasts along the macrophage lineage.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 4-15 protein_domain_or_region denotes zinc finger
T2 37-42 protein_molecule denotes Egr-1
T3 100-118 cell_type denotes macrophage lineage
T4 137-148 DNA_family_or_group denotes cDNA clones
T5 152-204 DNA_domain_or_region denotes myeloid differentiation primary response (MyD) genes
T6 317-327 cell_type denotes macrophage
T7 331-350 cell_type denotes granulocyte lineage
T8 360-393 cell_line denotes myeloblastic leukemia HL-60 cells
T9 399-409 DNA_molecule denotes cDNA clone
T10 493-498 protein_molecule denotes Egr-1
T11 502-534 protein_family_or_group denotes zinc finger transcription factor
T12 540-550 DNA_domain_or_region denotes Egr-1 gene
T13 598-609 cell_line denotes HL-60 cells
T14 625-630 cell_line denotes U-937
T15 635-643 cell_line denotes M1 cells
T16 712-717 protein_molecule denotes Egr-1
T17 745-758 other_name denotes culture media
T18 802-829 cell_line denotes myeloid leukemia cell lines
T19 841-852 cell_type denotes myeloblasts
T20 854-865 cell_line denotes HL-60 cells
T21 895-910 DNA_domain_or_region denotes Egr-1 transgene
T22 912-922 DNA_molecule denotes HL-60Egr-1
T23 945-955 cell_type denotes macrophage
T24 965-976 cell_type denotes granulocyte
T25 1042-1047 protein_molecule denotes Egr-1
T26 1079-1094 other_name denotes differentiation
T27 1098-1109 cell_type denotes myeloblasts
T28 1120-1138 cell_type denotes macrophage lineage

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 373-381 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059
T2 802-818 Disease denotes myeloid leukemia http://purl.obolibrary.org/obo/MONDO_0004643

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 354-359 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 9-15 Body_part denotes finger http://purl.obolibrary.org/obo/UBERON_0002389
T2 100-110 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T3 317-327 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T4 331-342 Body_part denotes granulocyte http://purl.obolibrary.org/obo/CL_0000094
T5 360-372 Body_part denotes myeloblastic http://purl.obolibrary.org/obo/CL_0000835
T6 453-463 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T7 507-513 Body_part denotes finger http://purl.obolibrary.org/obo/UBERON_0002389
T8 684-694 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T9 767-777 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T10 841-852 Body_part denotes myeloblasts http://purl.obolibrary.org/obo/CL_0000835
T11 945-955 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T12 965-976 Body_part denotes granulocyte http://purl.obolibrary.org/obo/CL_0000094
T13 1098-1109 Body_part denotes myeloblasts http://purl.obolibrary.org/obo/CL_0000835
T14 1120-1130 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 373-381 Phenotype denotes leukemia HP:0001909
T2 802-818 Phenotype denotes myeloid leukemia HP:0012324

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 100-110 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T3 317-327 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T5 331-342 Cell denotes granulocyte http://purl.obolibrary.org/obo/CL:0000094
T6 360-372 Cell denotes myeloblastic http://purl.obolibrary.org/obo/CL:0000835
T7 453-463 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T9 684-694 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T11 767-777 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T13 841-852 Cell denotes myeloblasts http://purl.obolibrary.org/obo/CL:0000835
T14 945-955 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T16 965-976 Cell denotes granulocyte http://purl.obolibrary.org/obo/CL:0000094
T17 1098-1109 Cell denotes myeloblasts http://purl.obolibrary.org/obo/CL:0000835
T18 1120-1130 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394