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PubMed:7657825 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 105-108 gene:6900 denotes tax
T1 61-82 disease:C0023493 denotes human T cell leukemia
R1 T0 T1 associated_with tax,human T cell leukemia

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 37-57 protein denotes Jak tyrosine kinases
T2 61-116 protein denotes human T cell leukemia virus type 1 (HTLV-1) tax protein
T3 120-143 cell_line denotes virus-transformed cells
T4 209-230 protein denotes viral encoded protein
T5 231-234 protein denotes tax
T6 323-326 protein denotes tax
T7 364-367 protein denotes tax
T8 379-396 cell_type denotes mouse fibroblasts
T9 405-415 cell_type denotes thymocytes
T10 446-449 protein denotes tax
T11 521-535 protein denotes 130-kD protein
T12 559-562 protein denotes tax
T13 563-592 cell_line denotes transformed fibroblast B line
T14 600-639 cell_line denotes HTLV-1 transformed human lymphoid lines
T15 652-662 cell_type denotes thymocytes
T16 777-807 protein denotes Jak kinase specific antibodies
T17 828-832 protein denotes Jak2
T18 840-843 protein denotes tax
T19 856-884 cell_line denotes mouse fibroblastic cell line
T20 889-893 protein denotes Jak3
T21 897-934 cell_line denotes HTLV-1 transformed human T cell lines
T22 955-959 protein denotes Jak2
T23 963-984 cell_line denotes tax transformed cells
T24 1090-1105 cell_line denotes Balb/c3T3 cells
T25 1135-1141 cell_line denotes B line
T26 1259-1287 protein denotes IL-6 neutralizing antibodies
T27 1321-1332 protein denotes Jak kinases
T28 1369-1398 cell_type denotes HTLV-1 infected human T cells

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7657825-0#105#108#gene6900 105-108 gene6900 denotes tax
7657825-0#61#82#diseaseC0023493 61-82 diseaseC0023493 denotes human T cell leukemia
105#108#gene690061#82#diseaseC0023493 7657825-0#105#108#gene6900 7657825-0#61#82#diseaseC0023493 associated_with tax,human T cell leukemia

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 27-57 NP denotes different Jak tyrosine kinases
C2 61-116 NP denotes human T cell leukemia virus type 1 (HTLV-1) tax protein
C3 205-234 NP denotes The viral encoded protein tax
C4 321-349 NP denotes a tax transgenic mouse model
C5 364-367 NP denotes tax
C6 555-592 NP denotes the tax transformed fibroblast B line
C7 600-639 NP denotes HTLV-1 transformed human lymphoid lines
C8 828-832 NP denotes Jak2
C9 836-884 NP denotes the tax transformed mouse fibroblastic cell line
C10 897-934 NP denotes HTLV-1 transformed human T cell lines
C11 955-959 NP denotes Jak2
C12 963-984 NP denotes tax transformed cells
C13 1018-1022 NP denotes IL-6
C14 1052-1064 NP denotes this protein
C15 1112-1141 NP denotes a supernatant from the B line
C16 1143-1148 NP denotes which
C17 1321-1332 NP denotes Jak kinases
C18 1369-1398 NP denotes HTLV-1 infected human T cells
C19 1403-1429 NP denotes the transgenic mouse model
R1 C3 C2 coref-ident The viral encoded protein tax,human T cell leukemia virus type 1 (HTLV-1) tax protein
R2 C5 C3 coref-ident tax,The viral encoded protein tax
R3 C9 C6 coref-ident the tax transformed mouse fibroblastic cell line,the tax transformed fibroblast B line
R4 C10 C7 coref-ident HTLV-1 transformed human T cell lines,HTLV-1 transformed human lymphoid lines
R5 C11 C8 coref-ident Jak2,Jak2
R6 C12 C9 coref-ident tax transformed cells,the tax transformed mouse fibroblastic cell line
R7 C14 C13 coref-ident this protein,IL-6
R8 C16 C15 coref-relat which,a supernatant from the B line
R9 C17 C1 coref-ident Jak kinases,different Jak tyrosine kinases
R10 C18 C10 coref-ident HTLV-1 infected human T cells,HTLV-1 transformed human T cell lines
R11 C19 C4 coref-ident the transgenic mouse model,a tax transgenic mouse model

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-144 Sentence denotes Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells.
S2 145-204 Sentence denotes HTLV-1 infection causes an adult T cell leukemia in humans.
S3 205-288 Sentence denotes The viral encoded protein tax, is thought to play an important role in oncogenesis.
S4 289-477 Sentence denotes Our previous data obtained from a tax transgenic mouse model revealed that tax transforms mouse fibroblasts but not thymocytes, despite comparable levels of tax expression in both tissues.
S5 478-692 Sentence denotes Constitutive tyrosine phosphorylation of a 130-kD protein(s) was observed in the tax transformed fibroblast B line and in HTLV-1 transformed human lymphoid lines, but not in thymocytes from Thy-tax transgenic mice.
S6 693-935 Sentence denotes Phosphotyrosine immunoprecipitation followed by Western blot analysis with a set of Jak kinase specific antibodies, identified p130 as Jak2 in the tax transformed mouse fibroblastic cell line and Jak3 in HTLV-1 transformed human T cell lines.
S7 936-1023 Sentence denotes Phosphorylation of Jak2 in tax transformed cells resulted from high expression of IL-6.
S8 1024-1201 Sentence denotes Tyrosine phosphorylation of this protein could also be induced in Balb/c3T3 cells using a supernatant from the B line, which was associated with induction of cell proliferation.
S9 1202-1288 Sentence denotes Both phosphorylation and proliferation were inhibited by IL-6 neutralizing antibodies.
S10 1289-1430 Sentence denotes Constitutive phosphorylation of Jak kinases may facilitate tumor growth in both HTLV-1 infected human T cells and the transgenic mouse model.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 37-40 protein_family_or_group denotes Jak
T2 41-49 amino_acid_monomer denotes tyrosine
T3 61-95 virus denotes human T cell leukemia virus type 1
T4 97-103 virus denotes HTLV-1
T5 120-143 cell_line denotes virus-transformed cells
T6 145-151 virus denotes HTLV-1
T7 172-193 other_name denotes adult T cell leukemia
T8 197-203 multi_cell denotes humans
T9 209-230 protein_family_or_group denotes viral encoded protein
T10 231-234 protein_molecule denotes tax
T11 276-287 other_name denotes oncogenesis
T12 323-326 protein_molecule denotes tax
T13 364-367 protein_molecule denotes tax
T14 379-396 cell_type denotes mouse fibroblasts
T15 405-415 cell_type denotes thymocytes
T16 446-449 protein_molecule denotes tax
T17 491-499 amino_acid_monomer denotes tyrosine
T18 521-535 protein_family_or_group denotes 130-kD protein
T19 559-562 protein_molecule denotes tax
T20 563-592 cell_line denotes transformed fibroblast B line
T21 600-606 virus denotes HTLV-1
T22 652-662 cell_type denotes thymocytes
T23 668-691 other_artificial_source denotes Thy-tax transgenic mice
T24 693-728 other_name denotes Phosphotyrosine immunoprecipitation
T25 741-762 other_name denotes Western blot analysis
T26 777-787 protein_family_or_group denotes Jak kinase
T27 828-832 protein_molecule denotes Jak2
T28 840-843 protein_molecule denotes tax
T29 856-884 cell_line denotes mouse fibroblastic cell line
T30 889-893 protein_molecule denotes Jak3
T31 897-903 virus denotes HTLV-1
T32 955-959 protein_molecule denotes Jak2
T33 963-966 protein_molecule denotes tax
T34 1024-1032 amino_acid_monomer denotes Tyrosine
T35 1090-1105 cell_line denotes Balb/c3T3 cells
T36 1135-1141 cell_line denotes B line
T37 1182-1200 other_name denotes cell proliferation
T38 1207-1222 other_name denotes phosphorylation
T39 1227-1240 other_name denotes proliferation
T40 1259-1263 protein_N/A denotes IL-6
T41 1321-1332 protein_family_or_group denotes Jak kinases
T42 1348-1360 other_name denotes tumor growth
T43 1369-1375 virus denotes HTLV-1
T44 1391-1398 cell_type denotes T cells
T45 1407-1429 other_artificial_source denotes transgenic mouse model