> top > docs > PubMed:7622191 > annotations

PubMed:7622191 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 21-46 protein denotes IL-2 receptor alpha-chain
T2 50-66 cell_type denotes human peripheral
T3 71-85 cell_line denotes Jurkat T cells
T4 92-108 protein denotes protein kinase C
T5 167-180 protein denotes Ca(2+)-ATPase
T6 365-369 protein denotes IL-2
T7 373-387 cell_line denotes Jurkat T cells
T8 425-441 protein denotes protein kinase C
T9 443-446 protein denotes PKC
T10 482-501 protein denotes IL-2R alpha protein
T11 513-529 RNA denotes IL-2R alpha mRNA
T12 533-547 cell_line denotes Jurkat T cells
T13 598-609 protein denotes IL-2R alpha
T14 637-661 cell_type denotes human peripheral T cells
T15 702-712 protein denotes NF kappa B
T16 716-730 cell_line denotes Jurkat T cells
T17 786-797 protein denotes IL-2R alpha
T18 844-855 protein denotes IL-2R alpha
T19 883-918 protein denotes PMA- but not TG-induced IL-2R alpha
T20 939-942 protein denotes PKC
T21 965-1000 protein denotes TG- but not PMA-induced IL-2R alpha
T22 1117-1128 protein denotes IL-2R alpha
T23 1132-1145 cell_type denotes human T cells
T24 1156-1159 protein denotes PKC

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-131 Sentence denotes Thapsigargin induces IL-2 receptor alpha-chain in human peripheral and Jurkat T cells via a protein kinase C-independent mechanism.
S2 132-299 Sentence denotes Thapsigargin (TG), an inhibitor of Ca(2+)-ATPase, depletes intracellular Ca2+ stores and induces a sustained Ca2+ influx without altering phosphatidyl inositol levels.
S3 300-448 Sentence denotes TG plus phorbol myristate acetate (PMA) but not TG alone induced IL-2 in Jurkat T cells, suggesting that TG had no effect on protein kinase C (PKC).
S4 449-575 Sentence denotes However, TG induced increases in IL-2R alpha protein as well as IL-2R alpha mRNA in Jurkat T cells in a dose-dependent manner.
S5 576-662 Sentence denotes A similar increase in IL-2R alpha by TG was also observed in human peripheral T cells.
S6 663-731 Sentence denotes Further, like PMA, TG markedly induced NF kappa B in Jurkat T cells.
S7 732-882 Sentence denotes However, TG and PMA exhibited a synergistic action on IL-2R alpha expression, suggesting that TG and PMA induce IL-2R alpha through distinct pathways.
S8 883-1069 Sentence denotes PMA- but not TG-induced IL-2R alpha is inhibited by the PKC inhibitor H7, whereas TG- but not PMA-induced IL-2R alpha was inhibited by cholera toxin, forskolin and 1,9-dideoxy forskolin.
S9 1070-1180 Sentence denotes In toto, these results suggest that TG induces IL-2R alpha in human T cells through a PKC-independent pathway.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-12 NP denotes Thapsigargin
C2 90-130 NP denotes a protein kinase C-independent mechanism
C3 132-149 NP denotes Thapsigargin (TG)
C4 151-180 NP denotes an inhibitor of Ca(2+)-ATPase
C5 300-302 NP denotes TG
C6 308-339 NP denotes phorbol myristate acetate (PMA)
C7 348-350 NP denotes TG
C8 373-387 NP denotes Jurkat T cells
C9 405-407 NP denotes TG
C10 458-460 NP denotes TG
C11 533-547 NP denotes Jurkat T cells
C12 598-609 NP denotes IL-2R alpha
C13 613-615 NP denotes TG
C14 677-680 NP denotes PMA
C15 682-684 NP denotes TG
C16 716-730 NP denotes Jurkat T cells
C17 741-743 NP denotes TG
C18 748-751 NP denotes PMA
C19 826-828 NP denotes TG
C20 833-836 NP denotes PMA
C21 844-855 NP denotes IL-2R alpha
C22 1106-1108 NP denotes TG
C23 1117-1128 NP denotes IL-2R alpha
C24 1154-1179 NP denotes a PKC-independent pathway
R1 C3 C1 coref-ident Thapsigargin (TG),Thapsigargin
R2 C4 C3 coref-appos an inhibitor of Ca(2+)-ATPase,Thapsigargin (TG)
R3 C5 C3 coref-ident TG,Thapsigargin (TG)
R4 C7 C5 coref-ident TG,TG
R5 C9 C7 coref-ident TG,TG
R6 C10 C9 coref-ident TG,TG
R7 C11 C8 coref-ident Jurkat T cells,Jurkat T cells
R8 C13 C10 coref-ident TG,TG
R9 C14 C6 coref-ident PMA,phorbol myristate acetate (PMA)
R10 C15 C13 coref-ident TG,TG
R11 C16 C11 coref-ident Jurkat T cells,Jurkat T cells
R12 C17 C15 coref-ident TG,TG
R13 C18 C14 coref-ident PMA,PMA
R14 C19 C17 coref-ident TG,TG
R15 C20 C18 coref-ident PMA,PMA
R16 C21 C12 coref-ident IL-2R alpha,IL-2R alpha
R17 C22 C19 coref-ident TG,TG
R18 C23 C21 coref-ident IL-2R alpha,IL-2R alpha
R19 C24 C2 coref-ident a PKC-independent pathway,a protein kinase C-independent mechanism

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-12 other_organic_compound denotes Thapsigargin
T2 21-46 protein_subunit denotes IL-2 receptor alpha-chain
T3 50-66 cell_type denotes human peripheral
T4 71-85 cell_line denotes Jurkat T cells
T5 92-108 protein_molecule denotes protein kinase C
T6 132-144 other_organic_compound denotes Thapsigargin
T7 146-148 other_organic_compound denotes TG
T8 167-180 protein_complex denotes Ca(2+)-ATPase
T9 205-209 atom denotes Ca2+
T10 241-245 atom denotes Ca2+
T11 270-291 lipid denotes phosphatidyl inositol
T12 300-302 other_organic_compound denotes TG
T13 308-333 other_organic_compound denotes phorbol myristate acetate
T14 335-338 other_organic_compound denotes PMA
T15 348-350 other_organic_compound denotes TG
T16 365-369 protein_molecule denotes IL-2
T17 373-387 cell_line denotes Jurkat T cells
T18 405-407 other_organic_compound denotes TG
T19 425-441 protein_molecule denotes protein kinase C
T20 443-446 protein_molecule denotes PKC
T21 458-460 other_organic_compound denotes TG
T22 482-501 protein_molecule denotes IL-2R alpha protein
T23 513-529 RNA_molecule denotes IL-2R alpha mRNA
T24 533-547 cell_line denotes Jurkat T cells
T25 598-609 protein_molecule denotes IL-2R alpha
T26 613-615 other_organic_compound denotes TG
T27 637-661 cell_type denotes human peripheral T cells
T28 677-680 other_organic_compound denotes PMA
T29 682-684 other_organic_compound denotes TG
T30 702-712 protein_molecule denotes NF kappa B
T31 716-730 cell_line denotes Jurkat T cells
T32 741-743 other_organic_compound denotes TG
T33 748-751 other_organic_compound denotes PMA
T34 786-797 protein_subunit denotes IL-2R alpha
T35 826-828 other_organic_compound denotes TG
T36 833-836 other_organic_compound denotes PMA
T37 844-855 protein_subunit denotes IL-2R alpha
T38 883-886 other_organic_compound denotes PMA
T39 896-898 other_organic_compound denotes TG
T40 939-942 protein_molecule denotes PKC
T41 965-967 other_organic_compound denotes TG
T42 977-980 other_organic_compound denotes PMA
T43 1018-1031 other_organic_compound denotes cholera toxin
T44 1033-1042 other_organic_compound denotes forskolin
T45 1047-1068 other_organic_compound denotes 1,9-dideoxy forskolin
T46 1106-1108 other_organic_compound denotes TG
T47 1117-1128 protein_subunit denotes IL-2R alpha
T48 1132-1145 cell_type denotes human T cells
T49 1156-1159 protein_molecule denotes PKC