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PubMed:7613138 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 4-17 protein denotes interleukin-5
T2 49-78 protein denotes Lyn and Jak2 tyrosine kinases
T3 110-130 protein denotes Ras-Raf-1-MAP kinase
T4 139-142 protein denotes Jak
T5 142-147 protein denotes -STAT
T6 160-171 cell_type denotes eosinophils
T7 211-229 protein denotes interleukin (IL)-5
T8 258-277 protein denotes Lyn tyrosine kinase
T9 295-315 protein denotes Jak2 tyrosine kinase
T10 332-336 protein denotes IL-5
T11 368-374 protein denotes p21ras
T12 440-445 protein denotes Raf-1
T13 447-450 protein denotes MEK
T14 456-467 protein denotes MAP kinases
T15 554-565 protein denotes Jak2 kinase
T16 598-619 protein denotes STAT nuclear proteins
T17 639-659 protein denotes STAT nuclear factors
T18 720-741 DNA denotes gamma activation site
T19 743-746 DNA denotes GAS
T20 769-773 protein denotes IL-5
T21 786-806 protein denotes GAS-binding proteins
T22 810-821 cell_type denotes eosinophils
T23 839-844 protein denotes STAT1
T24 863-867 protein denotes IL-5
T25 934-937 protein denotes Lyn
T26 940-943 protein denotes Ras
T27 946-951 protein denotes Raf-1
T28 954-957 protein denotes MEK
T29 960-970 protein denotes MAP kinase
T30 979-983 protein denotes Jak2
T31 986-991 protein denotes STAT1

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-172 Sentence denotes The interleukin-5/receptor interaction activates Lyn and Jak2 tyrosine kinases and propagates signals via the Ras-Raf-1-MAP kinase and the Jak-STAT pathways in eosinophils.
S2 173-331 Sentence denotes We have shown that the interaction of interleukin (IL)-5 with the receptor activates Lyn tyrosine kinase within 1 min and Jak2 tyrosine kinase within 1-3 min.
S3 332-375 Sentence denotes IL-5 also stimulates GTP binding to p21ras.
S4 376-553 Sentence denotes The signal is subsequently propagated through the activation of Raf-1, MEK, and MAP kinases as shown by their increased autophosphorylation in vitro and phosphorylation in situ.
S5 554-620 Sentence denotes Jak2 kinase has been shown to phosphorylate STAT nuclear proteins.
S6 621-754 Sentence denotes The activation of STAT nuclear factors was studied by electrophoretic mobility shift assay using a gamma activation site (GAS) probe.
S7 755-845 Sentence denotes We found that IL-5 induces two GAS-binding proteins in eosinophils, one of which is STAT1.
S8 846-992 Sentence denotes We conclude that IL-5 induced signals are propagated through two distinct pathways: (1) Lyn-->Ras-->Raf-1-->MEK-->MAP kinase and (2) Jak2-->STAT1.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 160-171 NP denotes eosinophils
C2 211-229 NP denotes interleukin (IL)-5
C3 295-315 NP denotes Jak2 tyrosine kinase
C4 332-336 NP denotes IL-5
C5 440-467 NP denotes Raf-1, MEK, and MAP kinases
C6 480-485 NP denotes their
C7 554-565 NP denotes Jak2 kinase
C8 769-773 NP denotes IL-5
C10 810-821 NP denotes eosinophils
C9 782-821 NP denotes two GAS-binding proteins in eosinophils
C11 830-835 NP denotes which
R1 C4 C2 coref-ident IL-5,interleukin (IL)-5
R2 C6 C5 coref-pron their,"Raf-1, MEK, and MAP kinases"
R3 C7 C3 coref-ident Jak2 kinase,Jak2 tyrosine kinase
R4 C8 C4 coref-ident IL-5,IL-5
R5 C10 C1 coref-ident eosinophils,eosinophils
R6 C11 C9 coref-relat which,two GAS-binding proteins in eosinophils

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 4-17 protein_family_or_group denotes interleukin-5
T2 110-130 protein_molecule denotes Ras-Raf-1-MAP kinase
T3 139-142 protein_family_or_group denotes Jak
T4 142-147 protein_family_or_group denotes -STAT
T5 160-171 cell_type denotes eosinophils
T6 211-229 protein_molecule denotes interleukin (IL)-5
T7 258-277 protein_molecule denotes Lyn tyrosine kinase
T8 295-315 protein_molecule denotes Jak2 tyrosine kinase
T9 332-336 protein_molecule denotes IL-5
T10 353-356 nucleotide denotes GTP
T11 368-374 protein_molecule denotes p21ras
T12 440-445 protein_molecule denotes Raf-1
T13 447-450 protein_family_or_group denotes MEK
T14 456-467 protein_family_or_group denotes MAP kinases
T15 496-515 other_name denotes autophosphorylation
T16 529-544 other_name denotes phosphorylation
T17 554-565 protein_molecule denotes Jak2 kinase
T18 598-602 protein_family_or_group denotes STAT
T19 603-619 protein_family_or_group denotes nuclear proteins
T20 639-659 protein_family_or_group denotes STAT nuclear factors
T21 675-711 other_name denotes electrophoretic mobility shift assay
T22 720-741 DNA_domain_or_region denotes gamma activation site
T23 743-746 DNA_domain_or_region denotes GAS
T24 769-773 protein_molecule denotes IL-5
T25 786-806 protein_family_or_group denotes GAS-binding proteins
T26 810-821 cell_type denotes eosinophils
T27 839-844 protein_molecule denotes STAT1
T28 863-867 protein_molecule denotes IL-5
T29 934-937 protein_family_or_group denotes Lyn
T30 940-943 protein_family_or_group denotes Ras
T31 946-951 protein_molecule denotes Raf-1
T32 954-957 protein_family_or_group denotes MEK
T33 960-970 protein_family_or_group denotes MAP kinase
T34 979-983 protein_molecule denotes Jak2
T35 986-991 protein_molecule denotes STAT1