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sentences

Id Subject Object Predicate Lexical cue
T1 0-117 Sentence denotes Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.
T2 118-287 Sentence denotes T cell expression of interleukin 3 (IL-3) is directed by positive and negative cis-acting DNA elements clustered within 300 base pairs of the transcriptional start site.
T3 288-447 Sentence denotes A strong repressor element, termed nuclear inhibitory protein (NIP), was previously mapped to a segment of the IL-3 promoter between nucleotides -271 and -250.
T4 448-582 Sentence denotes Functional characterization of this element demonstrates that it can mediate repression when linked in cis to a heterologous promoter.
T5 583-663 Sentence denotes DNA binding experiments were carried out to characterize the repressor activity.
T6 664-825 Sentence denotes Using varying conditions, three distinct complexes were shown to interact specifically with the NIP region, although only one correlates with repressor activity.
T7 826-968 Sentence denotes Complex 1 results from binding of a ubiquitous polypeptide that recognizes the 3' portion of this sequence and is not required for repression.
T8 969-1110 Sentence denotes Complex 2 corresponds to binding of transcription factor (upstream stimulatory factor) to an E-box motif in the 5' portion of the NIP region.
T9 1111-1222 Sentence denotes DNA binding specificity of complex 3 overlaps with that of upstream stimulatory factor but is clearly distinct.
T10 1223-1447 Sentence denotes To determine which of the latter two complexes represents NIP activity, we incorporated small alterations into the NIP site of an IL-3 promoter-linked reporter construct and examined their effects on NIP-mediated repression.
T11 1448-1623 Sentence denotes Functional specificity for repression matches the DNA binding specificity of complex 3; both repressor activity and complex 3 binding require the consensus sequence CTCACNTNC.
T1 0-117 Sentence denotes Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.
T2 118-287 Sentence denotes T cell expression of interleukin 3 (IL-3) is directed by positive and negative cis-acting DNA elements clustered within 300 base pairs of the transcriptional start site.
T3 288-447 Sentence denotes A strong repressor element, termed nuclear inhibitory protein (NIP), was previously mapped to a segment of the IL-3 promoter between nucleotides -271 and -250.
T4 448-582 Sentence denotes Functional characterization of this element demonstrates that it can mediate repression when linked in cis to a heterologous promoter.
T5 583-663 Sentence denotes DNA binding experiments were carried out to characterize the repressor activity.
T6 664-825 Sentence denotes Using varying conditions, three distinct complexes were shown to interact specifically with the NIP region, although only one correlates with repressor activity.
T7 826-968 Sentence denotes Complex 1 results from binding of a ubiquitous polypeptide that recognizes the 3' portion of this sequence and is not required for repression.
T8 969-1110 Sentence denotes Complex 2 corresponds to binding of transcription factor (upstream stimulatory factor) to an E-box motif in the 5' portion of the NIP region.
T9 1111-1222 Sentence denotes DNA binding specificity of complex 3 overlaps with that of upstream stimulatory factor but is clearly distinct.
T10 1223-1447 Sentence denotes To determine which of the latter two complexes represents NIP activity, we incorporated small alterations into the NIP site of an IL-3 promoter-linked reporter construct and examined their effects on NIP-mediated repression.
T11 1448-1623 Sentence denotes Functional specificity for repression matches the DNA binding specificity of complex 3; both repressor activity and complex 3 binding require the consensus sequence CTCACNTNC.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 36-80 DNA denotes nuclear inhibitory protein repressor element
T2 88-116 DNA denotes human interleukin-3 promoter
T3 139-152 protein denotes interleukin 3
T4 154-158 protein denotes IL-3
T5 175-220 DNA denotes positive and negative cis-acting DNA elements
T6 260-286 DNA denotes transcriptional start site
T7 297-314 protein denotes repressor element
T8 323-349 protein denotes nuclear inhibitory protein
T9 351-354 protein denotes NIP
T10 399-412 DNA denotes IL-3 promoter
T11 421-446 DNA denotes nucleotides -271 and -250
T12 560-581 DNA denotes heterologous promoter
T13 760-770 DNA denotes NIP region
T14 826-835 protein denotes Complex 1
T15 905-915 DNA denotes 3' portion
T16 969-978 protein denotes Complex 2
T17 1005-1025 protein denotes transcription factor
T18 1027-1054 protein denotes upstream stimulatory factor
T19 1062-1073 DNA denotes E-box motif
T20 1081-1091 DNA denotes 5' portion
T21 1099-1109 DNA denotes NIP region
T22 1170-1197 protein denotes upstream stimulatory factor
T23 1281-1284 protein denotes NIP
T24 1338-1346 DNA denotes NIP site
T25 1353-1392 DNA denotes IL-3 promoter-linked reporter construct
T26 1423-1426 protein denotes NIP
T27 1525-1534 protein denotes complex 3
T28 1564-1573 protein denotes complex 3
T29 1594-1612 DNA denotes consensus sequence

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-117 Sentence denotes Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.
S2 118-287 Sentence denotes T cell expression of interleukin 3 (IL-3) is directed by positive and negative cis-acting DNA elements clustered within 300 base pairs of the transcriptional start site.
S3 288-447 Sentence denotes A strong repressor element, termed nuclear inhibitory protein (NIP), was previously mapped to a segment of the IL-3 promoter between nucleotides -271 and -250.
S4 448-582 Sentence denotes Functional characterization of this element demonstrates that it can mediate repression when linked in cis to a heterologous promoter.
S5 583-663 Sentence denotes DNA binding experiments were carried out to characterize the repressor activity.
S6 664-825 Sentence denotes Using varying conditions, three distinct complexes were shown to interact specifically with the NIP region, although only one correlates with repressor activity.
S7 826-968 Sentence denotes Complex 1 results from binding of a ubiquitous polypeptide that recognizes the 3' portion of this sequence and is not required for repression.
S8 969-1110 Sentence denotes Complex 2 corresponds to binding of transcription factor (upstream stimulatory factor) to an E-box motif in the 5' portion of the NIP region.
S9 1111-1222 Sentence denotes DNA binding specificity of complex 3 overlaps with that of upstream stimulatory factor but is clearly distinct.
S10 1223-1447 Sentence denotes To determine which of the latter two complexes represents NIP activity, we incorporated small alterations into the NIP site of an IL-3 promoter-linked reporter construct and examined their effects on NIP-mediated repression.
S11 1448-1623 Sentence denotes Functional specificity for repression matches the DNA binding specificity of complex 3; both repressor activity and complex 3 binding require the consensus sequence CTCACNTNC.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 32-80 NP denotes the nuclear inhibitory protein repressor element
C2 84-116 NP denotes the human interleukin-3 promoter
C3 288-314 NP denotes A strong repressor element
C4 323-355 NP denotes nuclear inhibitory protein (NIP)
C5 395-412 NP denotes the IL-3 promoter
C6 479-491 NP denotes this element
C7 510-512 NP denotes it
C8 640-662 NP denotes the repressor activity
C9 756-770 NP denotes the NIP region
C10 806-824 NP denotes repressor activity
C11 826-835 NP denotes Complex 1
C12 860-884 NP denotes a ubiquitous polypeptide
C13 885-889 NP denotes that
C14 919-932 NP denotes this sequence
C15 1005-1055 NP denotes transcription factor (upstream stimulatory factor)
C16 1095-1109 NP denotes the NIP region
C18 1111-1134 NP denotes DNA binding specificity
C19 1138-1147 NP denotes complex 3
C17 1111-1147 NP denotes DNA binding specificity of complex 3
C20 1162-1166 NP denotes that
C21 1170-1197 NP denotes upstream stimulatory factor
C22 1311-1328 NP denotes small alterations
C23 1406-1411 NP denotes their
C25 1525-1534 NP denotes complex 3
C24 1494-1534 NP denotes the DNA binding specificity of complex 3
C26 1541-1559 NP denotes repressor activity
R1 C3 C1 coref-ident A strong repressor element,the nuclear inhibitory protein repressor element
R2 C4 C3 coref-ident nuclear inhibitory protein (NIP),A strong repressor element
R3 C5 C2 coref-ident the IL-3 promoter,the human interleukin-3 promoter
R4 C6 C4 coref-ident this element,nuclear inhibitory protein (NIP)
R5 C7 C6 coref-pron it,this element
R6 C10 C8 coref-ident repressor activity,the repressor activity
R7 C13 C12 coref-relat that,a ubiquitous polypeptide
R8 C14 C11 coref-ident this sequence,Complex 1
R9 C16 C9 coref-ident the NIP region,the NIP region
R10 C20 C18 coref-pron that,DNA binding specificity
R11 C21 C15 coref-ident upstream stimulatory factor,transcription factor (upstream stimulatory factor)
R12 C23 C22 coref-pron their,small alterations
R13 C25 C19 coref-ident complex 3,complex 3
R14 C24 C17 coref-ident the DNA binding specificity of complex 3,DNA binding specificity of complex 3
R15 C26 C10 coref-ident repressor activity,repressor activity

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 36-80 DNA_domain_or_region denotes nuclear inhibitory protein repressor element
T2 88-116 DNA_domain_or_region denotes human interleukin-3 promoter
T3 139-152 protein_molecule denotes interleukin 3
T4 154-158 protein_molecule denotes IL-3
T5 260-286 DNA_domain_or_region denotes transcriptional start site
T6 297-314 protein_family_or_group denotes repressor element
T7 323-349 protein_molecule denotes nuclear inhibitory protein
T8 351-354 protein_molecule denotes NIP
T9 399-412 DNA_domain_or_region denotes IL-3 promoter
T10 421-446 DNA_domain_or_region denotes nucleotides -271 and -250
T11 525-535 other_name denotes repression
T12 560-581 DNA_domain_or_region denotes heterologous promoter
T13 583-606 other_name denotes DNA binding experiments
T14 644-662 other_name denotes repressor activity
T15 760-763 protein_molecule denotes NIP
T16 806-824 other_name denotes repressor activity
T17 826-835 protein_complex denotes Complex 1
T18 862-884 peptide denotes ubiquitous polypeptide
T19 905-915 DNA_domain_or_region denotes 3' portion
T20 957-967 other_name denotes repression
T21 969-978 protein_complex denotes Complex 2
T22 1005-1025 protein_family_or_group denotes transcription factor
T23 1027-1054 protein_family_or_group denotes upstream stimulatory factor
T24 1062-1073 DNA_domain_or_region denotes E-box motif
T25 1081-1091 DNA_domain_or_region denotes 5' portion
T26 1099-1102 protein_molecule denotes NIP
T27 1111-1134 other_name denotes DNA binding specificity
T28 1170-1197 protein_family_or_group denotes upstream stimulatory factor
T29 1281-1284 protein_molecule denotes NIP
T30 1338-1341 protein_molecule denotes NIP
T31 1353-1366 DNA_domain_or_region denotes IL-3 promoter
T32 1423-1426 protein_molecule denotes NIP
T33 1436-1446 other_name denotes repression
T34 1475-1485 other_name denotes repression
T35 1498-1521 other_name denotes DNA binding specificity
T36 1525-1534 protein_complex denotes complex 3
T37 1541-1559 other_name denotes repressor activity
T38 1564-1573 protein_complex denotes complex 3
T39 1594-1612 DNA_domain_or_region denotes consensus sequence
T40 1613-1622 polynucleotide denotes CTCACNTNC

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 88-93 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 118-124 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T2 384-391 Body_part denotes segment http://purl.obolibrary.org/obo/UBERON_0000914

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 118-124 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084