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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 14-62 protein denotes granulocyte-macrophage colony-stimulating factor
T2 67-77 protein denotes E-selectin
T3 92-109 cell_type denotes endothelial cells
T4 135-162 protein denotes T-cell transcription factor
T5 163-167 protein denotes NFAT
T6 169-204 protein denotes Nuclear factor of activated T cells
T7 206-210 protein denotes NFAT
T8 242-278 protein denotes T-cell-specific transcription factor
T9 313-321 protein denotes cytokine
T10 355-371 protein denotes immunoregulatory
T11 424-451 cell_type denotes activated endothelial cells
T12 467-471 protein denotes NFAT
T13 525-542 cell_type denotes endothelial cells
T14 602-606 protein denotes NFAT
T15 610-627 cell_type denotes endothelial cells
T16 658-740 DNA denotes granulocyte-macrophage colony-stimulating factor (GM-CSF) gene regulatory elements
T17 750-754 protein denotes NFAT
T18 814-825 RNA denotes GM-CSF mRNA
T19 852-879 cell_type denotes activated endothelial cells
T20 901-911 protein denotes E-selectin
T21 921-954 protein denotes vascular cell adhesion molecule-1
T22 956-962 protein denotes VCAM-1
T23 1013-1032 DNA denotes E-selectin promoter
T24 1049-1059 protein denotes NF-kappa B
T25 1072-1076 protein denotes NFAT
T26 1130-1157 protein denotes leukocyte adhesion molecule
T27 1161-1194 protein denotes tumor necrosis factor (TNF)-alpha
T28 1282-1292 cell_type denotes neutrophil
T29 1325-1342 cell_type denotes endothelial cells
T30 1369-1378 DNA denotes chromatin
T31 1399-1426 DNA denotes DNasel hypersensitive sites
T32 1443-1449 protein denotes GM-CSF
T33 1467-1486 DNA denotes E-selectin promoter
T34 1547-1551 protein denotes NFAT
T35 1555-1572 cell_type denotes endothelial cells

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 92-109 NP denotes endothelial cells
C2 113-126 NP denotes cyclosporin A
C3 131-167 NP denotes the T-cell transcription factor NFAT
C4 169-211 NP denotes Nuclear factor of activated T cells (NFAT)
C5 240-278 NP denotes a T-cell-specific transcription factor
C6 279-284 NP denotes athat
C7 383-402 NP denotes cyclosporin A (CsA)
C8 424-451 NP denotes activated endothelial cells
C9 467-471 NP denotes NFAT
C10 518-521 NP denotes CsA
C11 525-542 NP denotes endothelial cells
C12 559-562 NP denotes CsA
C13 602-606 NP denotes NFAT
C14 610-627 NP denotes endothelial cells
C15 658-740 NP denotes granulocyte-macrophage colony-stimulating factor (GM-CSF) gene regulatory elements
C16 741-745 NP denotes that
C17 750-754 NP denotes NFAT
C18 763-766 NP denotes CsA
C19 852-879 NP denotes activated endothelial cells
C20 881-884 NP denotes CsA
C21 978-995 NP denotes endothelial cells
C22 1009-1032 NP denotes the E-selectin promoter
C23 1072-1076 NP denotes NFAT
C24 1233-1236 NP denotes CsA
C25 1318-1321 NP denotes CsA
C26 1325-1342 NP denotes endothelial cells
C27 1463-1486 NP denotes the E-selectin promoter
C28 1506-1509 NP denotes CsA
C29 1547-1551 NP denotes NFAT
C30 1555-1572 NP denotes endothelial cells
C31 1586-1596 NP denotes mechanisms
C32 1600-1605 NP denotes which
C33 1606-1609 NP denotes CsA
R1 C4 C3 coref-ident Nuclear factor of activated T cells (NFAT),the T-cell transcription factor NFAT
R2 C6 C5 coref-relat athat,a T-cell-specific transcription factor
R3 C7 C2 coref-ident cyclosporin A (CsA),cyclosporin A
R4 C9 C4 coref-ident NFAT,Nuclear factor of activated T cells (NFAT)
R5 C10 C7 coref-ident CsA,cyclosporin A (CsA)
R6 C11 C1 coref-ident endothelial cells,endothelial cells
R7 C12 C10 coref-ident CsA,CsA
R8 C13 C9 coref-ident NFAT,NFAT
R9 C14 C11 coref-ident endothelial cells,endothelial cells
R10 C16 C15 coref-relat that,granulocyte-macrophage colony-stimulating factor (GM-CSF) gene regulatory elements
R11 C17 C13 coref-ident NFAT,NFAT
R12 C18 C12 coref-ident CsA,CsA
R13 C19 C8 coref-ident activated endothelial cells,activated endothelial cells
R14 C20 C18 coref-ident CsA,CsA
R15 C21 C14 coref-ident endothelial cells,endothelial cells
R16 C23 C17 coref-ident NFAT,NFAT
R17 C24 C20 coref-ident CsA,CsA
R18 C25 C24 coref-ident CsA,CsA
R19 C26 C21 coref-ident endothelial cells,endothelial cells
R20 C27 C22 coref-ident the E-selectin promoter,the E-selectin promoter
R21 C28 C25 coref-ident CsA,CsA
R22 C29 C23 coref-ident NFAT,NFAT
R23 C30 C26 coref-ident endothelial cells,endothelial cells
R24 C32 C31 coref-relat which,mechanisms
R25 C33 C28 coref-ident CsA,CsA

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-10 cui:C0851285 denotes Regulation
E2-ti-1 14-62 cui:C0079460 denotes granulocyte-macrophage colony-stimulating factor
E3-ti-1 67-77 cui:C0115305 denotes E-selectin
E4-ti-1 78-88 cui:C0185117 denotes expression
E5-ti-1 92-109 cui:C0225336 denotes endothelial cells
E6-ti-1 113-126 cui:C0010592 denotes cyclosporin A
E7-ti-1 142-155 cui:C0040649 denotes transcription
E8-ti-1 135-162 cui:C1566664 denotes T-cell transcription factor
E9-ti-1 163-167 cui:C0521447 denotes NFAT
E10-ti-1 163-167 cui:C1515877 denotes NFAT
T1 0-10 INTERACTS_WITH denotes Regulation
T2 0-10 INTERACTS_WITH denotes Regulation
T3 89-91 LOCATION_OF denotes in
T4 89-91 LOCATION_OF denotes in
E1-ab-1 169-204 cui:C0288011 denotes Nuclear factor of activated T cells
E2-ab-1 258-271 cui:C0040649 denotes transcription
E3-ab-1 242-278 cui:C1566664 denotes T-cell-specific transcription factor
E4-ab-1 313-321 cui:C0079189 denotes cytokine
E5-ab-1 322-337 cui:C0017262 denotes gene expression
E6-ab-1 372-379 cui:C1280500 denotes effects
E7-ab-1 383-396 cui:C0010592 denotes cyclosporin A
T5 299-309 STIMULATES denotes activation
E1-ab-2 424-433 cui:C1515877 denotes activated
E2-ab-2 434-451 cui:C0225336 denotes endothelial cells
E3-ab-2 467-471 cui:C0288011 denotes NFAT
E4-ab-2 504-514 cui:C0871161 denotes properties
E5-ab-2 518-521 cui:C0010592 denotes CsA
E6-ab-2 525-542 cui:C0225336 denotes endothelial cells
T6 457-466 PRODUCES denotes expressed
T7 522-524 LOCATION_OF denotes in
E1-ab-3 559-562 cui:C0010592 denotes CsA
E2-ab-3 589-598 cui:C0857127 denotes induction
E3-ab-3 602-606 cui:C0521447 denotes NFAT
E4-ab-3 602-606 cui:C1521761 denotes NFAT
E5-ab-3 602-606 cui:C1515877 denotes NFAT
E6-ab-3 602-606 cui:C0039194 denotes NFAT
E7-ab-3 610-627 cui:C0225336 denotes endothelial cells
E8-ab-3 646-654 cui:C0439167 denotes activity
E9-ab-3 658-706 cui:C0079460 denotes granulocyte-macrophage colony-stimulating factor
E10-ab-3 716-720 cui:C0017337 denotes gene
E11-ab-3 721-740 cui:C1514827 denotes regulatory elements
E12-ab-3 750-754 cui:C0288011 denotes NFAT
T8 607-609 LOCATION_OF denotes in
E1-ab-4 763-766 cui:C0010592 denotes CsA
E2-ab-4 814-820 cui:C0079460 denotes GM-CSF
E3-ab-4 821-825 cui:C0035696 denotes mRNA
E4-ab-4 830-848 cui:C1171362 denotes protein expression
E5-ab-4 852-861 cui:C1515877 denotes activated
E6-ab-4 862-879 cui:C0225336 denotes endothelial cells
T9 811-813 COEXISTS_WITH denotes in
E1-ab-5 881-884 cui:C0010592 denotes CsA
E2-ab-5 890-900 cui:C1260953 denotes suppressed
E3-ab-5 903-911 cui:C0282651 denotes selectin
E4-ab-5 917-920 cui:C1518422 denotes not
E5-ab-5 921-954 cui:C0078056 denotes vascular cell adhesion molecule-1
E6-ab-5 964-974 cui:C0185117 denotes expression
E7-ab-5 978-995 cui:C0225336 denotes endothelial cells
E8-ab-5 1013-1023 cui:C0115305 denotes E-selectin
E9-ab-5 1049-1059 cui:C0079904 denotes NF-kappa B
E10-ab-5 1072-1076 cui:C0288011 denotes NFAT
T10 964-974 PART_OF denotes expression
T11 1036-1045 STIMULATES denotes activated
T12 1036-1045 STIMULATES denotes activated
E1-ab-6 1085-1094 cui:C0857127 denotes induction
E2-ab-6 1098-1110 cui:C0699040 denotes cell surface
E3-ab-6 1111-1121 cui:C0185117 denotes expression
E4-ab-6 1130-1157 cui:C0034822 denotes leukocyte adhesion molecule
E5-ab-6 1161-1194 cui:C1456820 denotes tumor necrosis factor (TNF)-alpha
E6-ab-6 1210-1213 cui:C0439509 denotes 40%
E7-ab-6 1233-1236 cui:C0010592 denotes CsA
E8-ab-6 1270-1278 cui:C0547047 denotes decrease
E9-ab-6 1282-1292 cui:C0027950 denotes neutrophil
E10-ab-6 1293-1301 cui:C0001511 denotes adhesion
T13 1085-1094 STIMULATES denotes induction
T14 1282-1301 LOCATION_OF denotes neutrophil adhesion
T15 1279-1281 ASSOCIATED_WITH denotes in
E1-ab-7 1307-1314 cui:C1280500 denotes effects
E2-ab-7 1318-1321 cui:C0010592 denotes CsA
E3-ab-7 1325-1342 cui:C0225336 denotes endothelial cells
E4-ab-7 1369-1388 cui:C1516511 denotes chromatin structure
E5-ab-7 1406-1420 cui:C0020517 denotes hypersensitive
E6-ab-7 1421-1426 cui:C0205145 denotes sites
E7-ab-7 1443-1449 cui:C0079460 denotes GM-CSF
E8-ab-7 1450-1458 cui:C0086222 denotes enhancer
E9-ab-7 1467-1477 cui:C0115305 denotes E-selectin
E10-ab-7 1506-1509 cui:C0010592 denotes CsA
T16 1307-1314 INTERACTS_WITH denotes effects
T17 1322-1324 LOCATION_OF denotes on
T18 1492-1502 INHIBITS denotes suppressed
E1-ab-8 1531-1536 cui:C1279901 denotes first
E2-ab-8 1547-1551 cui:C0521447 denotes NFAT
E3-ab-8 1547-1551 cui:C1521761 denotes NFAT
E4-ab-8 1547-1551 cui:C1515877 denotes NFAT
E5-ab-8 1547-1551 cui:C0039194 denotes NFAT
E6-ab-8 1555-1572 cui:C0225336 denotes endothelial cells
E7-ab-8 1586-1596 cui:C0441712 denotes mechanisms
E8-ab-8 1606-1609 cui:C0010592 denotes CsA
E9-ab-8 1631-1653 cui:C0003209 denotes antiinflammatory agent
R1 E6-ti-1 T1 subjectOf cyclosporin A,Regulation
R2 E2-ti-1 T1 objectOf granulocyte-macrophage colony-stimulating factor,Regulation
R3 E6-ti-1 T2 subjectOf cyclosporin A,Regulation
R4 E3-ti-1 T2 objectOf E-selectin,Regulation
R5 E5-ti-1 T3 subjectOf endothelial cells,in
R6 E3-ti-1 T3 objectOf E-selectin,in
R7 E5-ti-1 T4 subjectOf endothelial cells,in
R8 E2-ti-1 T4 objectOf granulocyte-macrophage colony-stimulating factor,in
R9 E1-ab-1 T5 subjectOf Nuclear factor of activated T cells,activation
R10 E4-ab-1 T5 objectOf cytokine,activation
R11 E2-ab-2 T6 subjectOf endothelial cells,expressed
R12 E3-ab-2 T6 objectOf NFAT,expressed
R13 E6-ab-2 T7 subjectOf endothelial cells,in
R14 E5-ab-2 T7 objectOf CsA,in
R15 E7-ab-3 T8 subjectOf endothelial cells,in
R16 E1-ab-3 T8 objectOf CsA,in
R17 E1-ab-4 T9 subjectOf CsA,in
R18 E2-ab-4 T9 objectOf GM-CSF,in
R19 E10-ab-5 T10 subjectOf NFAT,expression
R20 E7-ab-5 T10 objectOf endothelial cells,expression
R21 E9-ab-5 T11 subjectOf NF-kappa B,activated
R22 E8-ab-5 T11 objectOf E-selectin,activated
R23 E9-ab-5 T12 subjectOf NF-kappa B,activated
R24 E3-ab-5 T12 objectOf selectin,activated
R25 E5-ab-6 T13 subjectOf tumor necrosis factor (TNF)-alpha,induction
R26 E4-ab-6 T13 objectOf leukocyte adhesion molecule,induction
R27 E9-ab-6 T14 subjectOf neutrophil,neutrophil adhesion
R28 E10-ab-6 T14 objectOf adhesion,neutrophil adhesion
R29 E7-ab-6 T15 subjectOf CsA,in
R30 E10-ab-6 T15 objectOf adhesion,in
R31 E8-ab-7 T16 subjectOf enhancer,effects
R32 E2-ab-7 T16 objectOf CsA,effects
R33 E3-ab-7 T17 subjectOf endothelial cells,on
R34 E2-ab-7 T17 objectOf CsA,on
R35 E10-ab-7 T18 subjectOf CsA,suppressed
R36 E9-ab-7 T18 objectOf E-selectin,suppressed

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-168 Sentence denotes Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT.
S2 169-403 Sentence denotes Nuclear factor of activated T cells (NFAT) was originally described as a T-cell-specific transcription factor athat supported the activation of cytokine gene expression and mediated the immunoregulatory effects of cyclosporin A (CsA).
S3 404-543 Sentence denotes As we observed that activated endothelial cells also expressed NFAT, we tested the antiinflammatory properties of CsA in endothelial cells.
S4 544-762 Sentence denotes Significantly, CsA completely suppressed the induction of NFAT in endothelial cells and inhibited the activity of granulocyte-macrophage colony-stimulating factor (GM-CSF) gene regulatory elements that use NFAT by 60%.
S5 763-880 Sentence denotes CsA similarly mediated a reduction of up to 65% in GM-CSF mRNA and protein expression in activated endothelial cells.
S6 881-1077 Sentence denotes CsA also suppressed E-selectin, but not vascular cell adhesion molecule-1 (VCAM-1) expression in endothelial cells, even though the E-selectin promoter is activated by NF-kappa B rather than NFAT.
S7 1078-1302 Sentence denotes Hence, induction of cell surface expression of this leukocyte adhesion molecule by tumor necrosis factor (TNF)-alpha was reduced by 40% in the presence of CsA, and this was reflected by a 29% decrease in neutrophil adhesion.
S8 1303-1510 Sentence denotes The effects of CsA on endothelial cells were also detected at the chromatin structure level, as DNasel hypersensitive sites within both the GM-CSF enhancer and the E-selectin promoter were suppressed by CsA.
S9 1511-1654 Sentence denotes This represents the first report of NFAT in endothelial cells and suggests mechanisms by which CsA could function as an antiinflammatory agent.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 14-62 protein_molecule denotes granulocyte-macrophage colony-stimulating factor
T2 67-77 protein_molecule denotes E-selectin
T3 92-109 cell_type denotes endothelial cells
T4 113-126 other_organic_compound denotes cyclosporin A
T5 135-162 protein_family_or_group denotes T-cell transcription factor
T6 163-167 protein_molecule denotes NFAT
T7 169-204 protein_molecule denotes Nuclear factor of activated T cells
T8 206-210 protein_molecule denotes NFAT
T9 242-278 protein_family_or_group denotes T-cell-specific transcription factor
T10 313-321 protein_molecule denotes cytokine
T11 322-337 other_name denotes gene expression
T12 355-371 protein_family_or_group denotes immunoregulatory
T13 383-396 other_organic_compound denotes cyclosporin A
T14 398-401 other_organic_compound denotes CsA
T15 424-451 cell_type denotes activated endothelial cells
T16 467-471 protein_molecule denotes NFAT
T17 487-514 other_name denotes antiinflammatory properties
T18 518-521 other_organic_compound denotes CsA
T19 525-542 cell_type denotes endothelial cells
T20 559-562 other_organic_compound denotes CsA
T21 602-606 protein_molecule denotes NFAT
T22 610-627 cell_type denotes endothelial cells
T23 658-706 protein_molecule denotes granulocyte-macrophage colony-stimulating factor
T24 708-714 protein_molecule denotes GM-CSF
T25 750-754 protein_molecule denotes NFAT
T26 763-766 other_organic_compound denotes CsA
T27 814-820 protein_molecule denotes GM-CSF
T28 830-848 other_name denotes protein expression
T29 852-879 cell_type denotes activated endothelial cells
T30 881-884 other_organic_compound denotes CsA
T31 901-911 protein_molecule denotes E-selectin
T32 921-954 protein_molecule denotes vascular cell adhesion molecule-1
T33 956-962 protein_molecule denotes VCAM-1
T34 1013-1023 protein_molecule denotes E-selectin
T35 1049-1059 protein_molecule denotes NF-kappa B
T36 1072-1076 protein_molecule denotes NFAT
T37 1098-1121 other_name denotes cell surface expression
T38 1130-1157 protein_family_or_group denotes leukocyte adhesion molecule
T39 1161-1194 protein_molecule denotes tumor necrosis factor (TNF)-alpha
T40 1233-1236 other_organic_compound denotes CsA
T41 1282-1292 cell_type denotes neutrophil
T42 1318-1321 other_organic_compound denotes CsA
T43 1325-1342 cell_type denotes endothelial cells
T44 1369-1378 DNA_family_or_group denotes chromatin
T45 1399-1405 protein_family_or_group denotes DNasel
T46 1443-1449 protein_molecule denotes GM-CSF
T47 1467-1477 protein_molecule denotes E-selectin
T48 1506-1509 other_organic_compound denotes CsA
T49 1547-1551 protein_molecule denotes NFAT
T50 1555-1572 cell_type denotes endothelial cells
T51 1606-1609 other_organic_compound denotes CsA
T52 1631-1653 other_name denotes antiinflammatory agent

metamap-sample

Id Subject Object Predicate Lexical cue
T1 1468-1478 C0115305 denotes -selectin
T2 1014-1024 C0115305 denotes -selectin
T3 68-77 C0115305 denotes -selectin
T4 1607-1610 C0010592 denotes sA
T5 1234-1237 C0010592 denotes sA,
T6 882-885 C0010592 denotes sA
T7 764-767 C0010592 denotes sA
T8 560-562 C0010592 denotes sA
T9 519-522 C0010592 denotes sA
T10 384-397 C0010592 denotes yclosporin A
T11 114-127 C0010592 denotes yclosporin A
T12 1556-1573 C0225336 denotes ndothelial cells
T13 1326-1342 C0225336 denotes ndothelial cells
T14 979-996 C0225336 denotes ndothelial cells,
T15 863-880 C0225336 denotes ndothelial cells.
T16 611-628 C0225336 denotes ndothelial cells
T17 93-110 C0225336 denotes ndothelial cells
T18 1545-1552 C0288011 denotes f NFAT
T19 1073-1077 C0288011 denotes FAT.
T20 751-755 C0288011 denotes FAT
T21 600-607 C0288011 denotes f NFAT
T22 468-472 C0288011 denotes FAT,
T23 170-205 C0288011 denotes uclear factor of activated T cells
T24 1-11 C1327622 denotes egulation
T25 1444-1450 C1332791 denotes M-CSF
T26 815-821 C1332791 denotes M-CSF
T27 659-707 C1332791 denotes ranulocyte-macrophage colony-stimulating factor
T28 15-63 C1332791 denotes ranulocyte-macrophage colony-stimulating factor
T29 1112-1122 C0185117 denotes xpression
T30 965-975 C0185117 denotes xpression
T31 79-89 C0185117 denotes xpression
T32 138-142 C1269647 denotes ell
T33 243-249 C0039194 denotes -cell-
T34 1131-1158 C0034822 denotes eukocyte adhesion molecule
T35 1283-1293 C0027950 denotes eutrophil
T36 922-954 C0078056 denotes ascular cell adhesion molecule-1
T37 1294-1302 C0001511 denotes dhesion.
T38 1050-1060 C0079904 denotes F-kappa B
T39 1632-1654 C0003209 denotes ntiinflammatory agent.
T40 822-826 C0035696 denotes RNA
T41 1617-1625 C0031843 denotes unction
T42 259-272 C0040649 denotes ranscription
T43 747-750 C0042153 denotes se
T44 1493-1502 C1260953 denotes uppressed
T45 891-901 C1260953 denotes uppressed
T46 575-585 C1260953 denotes uppressed
T47 1037-1046 C1879547 denotes ctivated
T48 853-862 C1879547 denotes ctivated
T49 425-434 C1879547 denotes ctivated
T50 778-786 C0127400 denotes ediated
T51 343-351 C0127400 denotes ediated
T52 323-338 C0017262 denotes ene expression
T53 1479-1487 C0086860 denotes romoter
T54 1025-1033 C0086860 denotes romoter
T55 1271-1279 C0392756 denotes ecrease
T56 1200-1207 C0392756 denotes educed
T57 1308-1315 C1280500 denotes ffects
T58 373-380 C1280500 denotes ffects
T59 1086-1095 C0205263 denotes nduction
T60 590-599 C0205263 denotes nduction
T61 733-741 C0013879 denotes lements
T62 808-810 C0450385 denotes 5%
T63 633-641 C0311403 denotes nhibited
T64 411-419 C1441672 denotes bserved
T65 1222-1230 C0392148 denotes resence
T66 1517-1527 C1882932 denotes epresents
T67 286-295 C1521721 denotes upported
T68 477-482 C0392366 denotes ested
T69 1578-1586 C1705535 denotes uggests
T70 1451-1459 C0086222 denotes nhancer
T71 904-912 C1325391 denotes electin,
T72 1211-1213 C0439509 denotes 0%
T73 1370-1389 C1516511 denotes hromatin structure
T74 789-798 C0301630 denotes eduction
T75 831-849 C1171362 denotes rotein expression
T76 1587-1597 C0441712 denotes echanisms
T77 1252-1261 C0558058 denotes eflected
T78 1422-1427 C0205145 denotes ites
T79 1354-1362 C0442726 denotes etected
T80 1390-1395 C0441889 denotes evel,
T81 505-515 C0871161 denotes roperties
T82 250-258 C0205369 denotes pecific
T83 228-237 C1552738 denotes escribed
T84 1538-1544 C0684224 denotes eport
T85 647-655 C1561536 denotes ctivity
T86 564-574 C0205197 denotes ompletely
T87 1096-1110 C0699040 denotes f cell surface
T88 488-504 C1515999 denotes ntiinflammatory
T89 1532-1537 C0205435 denotes irst
T90 918-921 C1518422 denotes ot