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PubMed:7513249 JSONTXT

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c_corpus

Id Subject Object Predicate Lexical cue
T1 28-32 PR:P15532 denotes nm23
T2 28-32 PR:000011281 denotes nm23
T3 33-37 SO:0000704 denotes gene
T4 61-67 UBERON:0000310 denotes breast
T5 61-77 D001943 denotes breast carcinoma
T6 61-77 D001943 denotes breast carcinoma
T9 126-132 UBERON:0000310 denotes breast
T10 126-142 D001943 denotes breast carcinoma
T11 126-142 D001943 denotes breast carcinoma
T14 133-150 D044584 denotes carcinoma, ductal
T15 133-150 D044584 denotes carcinoma, ductal
T18 144-168 D002285 denotes ductal carcinoma in situ
T19 144-168 D002285 denotes ductal carcinoma in situ
T25 170-174 CVCL_5552 denotes DCIS
T24 170-174 D002285 denotes DCIS
T26 170-174 D002285 denotes DCIS
T29 180-205 D000071960 denotes lobular carcinoma in situ
T30 180-205 D000071960 denotes lobular carcinoma in situ
T35 373-382 D002277 denotes carcinoma
T36 373-382 D002277 denotes carcinoma
T38 397-401 CVCL_5552 denotes DCIS
T37 397-401 D002285 denotes DCIS
T39 397-401 D002285 denotes DCIS
T40 458-467 D002277 denotes carcinoma
T41 458-467 D002277 denotes carcinoma
T43 469-473 CVCL_5552 denotes DCIS
T42 469-473 D002285 denotes DCIS
T44 469-473 D002285 denotes DCIS
T45 664-674 D002277 denotes carcinomas
T46 664-674 D002277 denotes carcinomas
T47 697-701 SO:0000704 denotes gene
T48 711-715 PR:P15532 denotes nm23
T49 711-715 PR:000011281 denotes nm23
T50 765-775 D002277 denotes carcinomas
T51 765-775 D002277 denotes carcinomas
T52 834-837 PR:Q9PW70 denotes CIS
T53 834-837 O70512 denotes CIS
T54 834-837 Q9NSE2 denotes CIS
T55 834-837 Q62225 denotes CIS
T56 834-837 PR:000005503 denotes CIS
T57 834-837 PR:Q62225 denotes CIS
T58 834-837 Q2HJ53 denotes CIS
T60 834-837 Q9PW70 denotes CIS
T59 834-837 UBERON:0035925 denotes CIS
T62 849-852 PR:Q9PW70 denotes CIS
T63 849-852 O70512 denotes CIS
T64 849-852 Q9NSE2 denotes CIS
T65 849-852 Q62225 denotes CIS
T66 849-852 PR:000005503 denotes CIS
T67 849-852 PR:Q62225 denotes CIS
T68 849-852 Q2HJ53 denotes CIS
T70 849-852 Q9PW70 denotes CIS
T69 849-852 UBERON:0035925 denotes CIS
T71 963-967 PR:P15532 denotes nm23
T72 963-967 PR:000011281 denotes nm23
T73 968-972 SO:0000704 denotes gene
T74 1083-1092 D002277 denotes carcinoma
T75 1083-1092 D002277 denotes carcinoma
T76 1146-1155 D002277 denotes carcinoma
T77 1146-1155 D002277 denotes carcinoma
T78 1223-1226 PR:Q9PW70 denotes CIS
T79 1223-1226 O70512 denotes CIS
T80 1223-1226 Q9NSE2 denotes CIS
T81 1223-1226 Q62225 denotes CIS
T82 1223-1226 PR:000005503 denotes CIS
T83 1223-1226 PR:Q62225 denotes CIS
T84 1223-1226 Q2HJ53 denotes CIS
T86 1223-1226 Q9PW70 denotes CIS
T85 1223-1226 UBERON:0035925 denotes CIS
T88 1261-1265 CVCL_5552 denotes DCIS
T87 1261-1265 D002285 denotes DCIS
T89 1261-1265 D002285 denotes DCIS
T90 1281-1285 PR:P15532 denotes nm23
T91 1281-1285 PR:000011281 denotes nm23
T93 1301-1305 CVCL_5552 denotes DCIS
T92 1301-1305 D002285 denotes DCIS
T94 1301-1305 D002285 denotes DCIS
T95 1361-1364 PR:Q9PW70 denotes CIS
T96 1361-1364 O70512 denotes CIS
T97 1361-1364 Q9NSE2 denotes CIS
T98 1361-1364 Q62225 denotes CIS
T99 1361-1364 PR:000005503 denotes CIS
T100 1361-1364 PR:Q62225 denotes CIS
T101 1361-1364 Q2HJ53 denotes CIS
T103 1361-1364 Q9PW70 denotes CIS
T102 1361-1364 UBERON:0035925 denotes CIS
T104 1424-1427 PR:Q9PW70 denotes CIS
T105 1424-1427 O70512 denotes CIS
T106 1424-1427 Q9NSE2 denotes CIS
T107 1424-1427 Q62225 denotes CIS
T108 1424-1427 PR:000005503 denotes CIS
T109 1424-1427 PR:Q62225 denotes CIS
T110 1424-1427 Q2HJ53 denotes CIS
T112 1424-1427 Q9PW70 denotes CIS
T111 1424-1427 UBERON:0035925 denotes CIS
T114 1480-1484 CVCL_5552 denotes DCIS
T113 1480-1484 D002285 denotes DCIS
T115 1480-1484 D002285 denotes DCIS
T116 1545-1548 PR:Q9PW70 denotes CIS
T117 1545-1548 O70512 denotes CIS
T118 1545-1548 Q9NSE2 denotes CIS
T119 1545-1548 Q62225 denotes CIS
T120 1545-1548 PR:000005503 denotes CIS
T121 1545-1548 PR:Q62225 denotes CIS
T122 1545-1548 Q2HJ53 denotes CIS
T124 1545-1548 Q9PW70 denotes CIS
T123 1545-1548 UBERON:0035925 denotes CIS
T126 1593-1597 CVCL_5552 denotes DCIS
T125 1593-1597 D002285 denotes DCIS
T127 1593-1597 D002285 denotes DCIS
T129 1742-1746 CVCL_5552 denotes DCIS
T128 1742-1746 D002285 denotes DCIS
T130 1742-1746 D002285 denotes DCIS
T131 1896-1900 PR:P15532 denotes nm23
T132 1896-1900 PR:000011281 denotes nm23
T134 1911-1915 CVCL_5552 denotes DCIS
T133 1911-1915 D002285 denotes DCIS
T135 1911-1915 D002285 denotes DCIS

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1223-1226 gene:1154 denotes CIS
T1 1254-1260 disease:C0221228 denotes comedo
T2 1223-1226 gene:1154 denotes CIS
T3 1301-1305 disease:C0007124 denotes DCIS
T4 1281-1285 gene:4830 denotes nm23
T5 1254-1260 disease:C0221228 denotes comedo
T6 1281-1285 gene:4830 denotes nm23
T7 1261-1265 disease:C0007124 denotes DCIS
T8 1281-1285 gene:4830 denotes nm23
T9 1301-1305 disease:C0007124 denotes DCIS
R1 T0 T1 associated_with CIS,comedo
R2 T2 T3 associated_with CIS,DCIS
R3 T4 T5 associated_with nm23,comedo
R4 T6 T7 associated_with nm23,DCIS
R5 T8 T9 associated_with nm23,DCIS

UseCases_ArguminSci_Discourse

Id Subject Object Predicate Lexical cue
T1 0-78 DRI_Approach denotes Heterogeneous expression of nm23 gene product in noninvasive breast carcinoma.
T2 91-296 DRI_Background denotes The two major types of noninvasive breast carcinoma, ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS), are quite different in their histopathologic appearance and clinical implications.
T3 297-468 DRI_Background denotes LCIS is only a marker of an increased risk of later development of invasive carcinoma, whereas most DCIS lesions are at least nonobligate precursors of invasive carcinoma.
T4 469-615 DRI_Background denotes DCIS is a heterogeneous group of lesions composed of several distinct subtypes, with only the comedo subtype having immediate malignant potential.
T5 616-905 DRI_Background denotes The authors' purpose was to analyze noninvasive carcinomas for the presence of a gene product (nm23) indicative of a favorable prognosis in invasive carcinomas to determine differences (1) among the different types of CIS and (2) in CIS with and without an accompanying invasive component.
T6 915-1194 DRI_Background denotes Immunohistochemical methods were used to detect nm23 gene product in archival material from two groups of patients: Group 1 consisted of 54 cases of purely noninvasive carcinoma, and Group 2 consisted of 55 examples of noninvasive carcinoma associated with an invasive component.
T7 1204-1322 DRI_Outcome denotes Among the cases of CIS with no invasion, LCIS and comedo DCIS expressed more nm23 than noncomedo DCIS (P < or = 0.03).
T8 1323-1401 DRI_Approach denotes There were no differences among these CIS subtypes in the group with invasion.
T9 1402-1647 DRI_Outcome denotes Comparing subtypes of CIS in the groups with or without invasion, only comedo DCIS was significantly different, with greater expression in the CIS group with no invasion compared with comedo DCIS associated with an invasive component (P = 0.04).
T10 1661-1747 DRI_Background denotes These results support the special nature of LCIS and the heterogeneous nature of DCIS.
T11 1748-1880 DRI_Background denotes The in situ component attending an invasive component may be different from anatomically similar lesion without associated invasion.
T12 1881-1955 DRI_Challenge denotes The absence of nm23 in comedo DCIS may be indicative of invasive capacity.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7513249-0#28#32#gene4830 28-32 gene4830 denotes nm23
7513249-0#61#77#diseaseC0678222 61-77 diseaseC0678222 denotes breast carcinoma
7513249-11#15#19#gene4830 1896-1900 gene4830 denotes nm23
7513249-11#23#29#diseaseC0221228 1904-1910 diseaseC0221228 denotes comedo
7513249-11#30#34#diseaseC0007124 1911-1915 diseaseC0007124 denotes DCIS
7513249-8#22#25#gene1154 1424-1427 gene1154 denotes CIS
7513249-8#143#146#gene1154 1545-1548 gene1154 denotes CIS
7513249-8#71#77#diseaseC0221228 1473-1479 diseaseC0221228 denotes comedo
7513249-8#78#82#diseaseC0007124 1480-1484 diseaseC0007124 denotes DCIS
7513249-8#184#190#diseaseC0221228 1586-1592 diseaseC0221228 denotes comedo
7513249-8#191#195#diseaseC0007124 1593-1597 diseaseC0007124 denotes DCIS
7513249-8#184#190#diseaseC0221228 1586-1592 diseaseC0221228 denotes comedo
7513249-8#191#195#diseaseC0007124 1593-1597 diseaseC0007124 denotes DCIS
28#32#gene483061#77#diseaseC0678222 7513249-0#28#32#gene4830 7513249-0#61#77#diseaseC0678222 associated_with nm23,breast carcinoma
15#19#gene483023#29#diseaseC0221228 7513249-11#15#19#gene4830 7513249-11#23#29#diseaseC0221228 associated_with nm23,comedo
15#19#gene483030#34#diseaseC0007124 7513249-11#15#19#gene4830 7513249-11#30#34#diseaseC0007124 associated_with nm23,DCIS
22#25#gene115471#77#diseaseC0221228 7513249-8#22#25#gene1154 7513249-8#71#77#diseaseC0221228 associated_with CIS,comedo
22#25#gene115478#82#diseaseC0007124 7513249-8#22#25#gene1154 7513249-8#78#82#diseaseC0007124 associated_with CIS,DCIS
22#25#gene1154184#190#diseaseC0221228 7513249-8#22#25#gene1154 7513249-8#184#190#diseaseC0221228 associated_with CIS,comedo
22#25#gene1154191#195#diseaseC0007124 7513249-8#22#25#gene1154 7513249-8#191#195#diseaseC0007124 associated_with CIS,DCIS
22#25#gene1154184#190#diseaseC0221228 7513249-8#22#25#gene1154 7513249-8#184#190#diseaseC0221228 associated_with CIS,comedo
22#25#gene1154191#195#diseaseC0007124 7513249-8#22#25#gene1154 7513249-8#191#195#diseaseC0007124 associated_with CIS,DCIS
143#146#gene115471#77#diseaseC0221228 7513249-8#143#146#gene1154 7513249-8#71#77#diseaseC0221228 associated_with CIS,comedo
143#146#gene115478#82#diseaseC0007124 7513249-8#143#146#gene1154 7513249-8#78#82#diseaseC0007124 associated_with CIS,DCIS
143#146#gene1154184#190#diseaseC0221228 7513249-8#143#146#gene1154 7513249-8#184#190#diseaseC0221228 associated_with CIS,comedo
143#146#gene1154191#195#diseaseC0007124 7513249-8#143#146#gene1154 7513249-8#191#195#diseaseC0007124 associated_with CIS,DCIS
143#146#gene1154184#190#diseaseC0221228 7513249-8#143#146#gene1154 7513249-8#184#190#diseaseC0221228 associated_with CIS,comedo
143#146#gene1154191#195#diseaseC0007124 7513249-8#143#146#gene1154 7513249-8#191#195#diseaseC0007124 associated_with CIS,DCIS