PubMed:7478623
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-3 | protein | denotes | Bik |
| T2 | 13-35 | protein | denotes | death-inducing protein |
| T3 | 74-95 | protein | denotes | Bcl-2 family proteins |
| T4 | 125-161 | protein | denotes | cellular survival-promoting proteins |
| T5 | 202-214 | protein | denotes | Bcl-2 family |
| T6 | 283-300 | protein | denotes | cellular proteins |
| T7 | 329-345 | protein | denotes | cellular protein |
| T8 | 347-350 | protein | denotes | Bik |
| T9 | 376-412 | protein | denotes | cellular survival-promoting proteins |
| T10 | 414-419 | protein | denotes | Bcl-2 |
| T11 | 424-430 | protein | denotes | Bcl-xL |
| T12 | 447-480 | protein | denotes | viral survival-promoting proteins |
| T13 | 482-506 | protein | denotes | Epstein Barr virus-BHRF1 |
| T14 | 511-532 | protein | denotes | adenovirus E1B-19 kDa |
| T15 | 568-571 | protein | denotes | Bik |
| T16 | 619-642 | protein | denotes | death-promoting members |
| T17 | 650-662 | protein | denotes | Bcl-2 family |
| T18 | 664-667 | protein | denotes | Bax |
| T19 | 672-675 | protein | denotes | Bak |
| T20 | 710-713 | protein | denotes | Bik |
| T21 | 751-756 | protein | denotes | Bcl-2 |
| T22 | 758-764 | protein | denotes | Bcl-XL |
| T23 | 766-775 | protein | denotes | EBV-BHRF1 |
| T24 | 780-790 | protein | denotes | E1B-19 kDa |
| T25 | 816-819 | protein | denotes | Bik |
| T26 | 852-894 | protein | denotes | cellular and viral anti-apoptotic proteins |
| T27 | 902-905 | protein | denotes | Bik |
| T28 | 942-945 | protein | denotes | BH1 |
| T29 | 950-953 | protein | denotes | BH2 |
| T30 | 994-1006 | protein | denotes | Bcl-2 family |
| T31 | 1026-1043 | protein | denotes | amino acid domain |
| T32 | 1045-1048 | protein | denotes | BH3 |
| T33 | 1055-1058 | protein | denotes | Bax |
| T34 | 1063-1066 | protein | denotes | Bak |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-3 | NP | denotes | Bik |
| C2 | 5-35 | NP | denotes | a novel death-inducing protein |
| C3 | 74-95 | NP | denotes | Bcl-2 family proteins |
| C4 | 198-226 | NP | denotes | the Bcl-2 family of proteins |
| C6 | 321-345 | NP | denotes | a novel cellular protein |
| C7 | 347-350 | NP | denotes | Bik |
| C8 | 352-356 | NP | denotes | that |
| C9 | 372-412 | NP | denotes | the cellular survival-promoting proteins |
| C10 | 414-430 | NP | denotes | Bcl-2 and Bcl-xL |
| C11 | 443-480 | NP | denotes | the viral survival-promoting proteins |
| C12 | 482-532 | NP | denotes | Epstein Barr virus-BHRF1 and adenovirus E1B-19 kDa |
| C5 | 321-532 | NP | denotes | a novel cellular protein, Bik, that interacts with the cellular survival-promoting proteins, Bcl-2 and Bcl-xL, as well as the viral survival-promoting proteins, Epstein Barr virus-BHRF1 and adenovirus E1B-19 kDa |
| C13 | 568-571 | NP | denotes | Bik |
| C15 | 646-662 | NP | denotes | the Bcl-2 family |
| C16 | 664-675 | NP | denotes | Bax and Bak |
| C14 | 615-675 | NP | denotes | the death-promoting members of the Bcl-2 family, Bax and Bak |
| C17 | 710-713 | NP | denotes | Bik |
| C18 | 816-819 | NP | denotes | Bik |
| C19 | 902-905 | NP | denotes | Bik |
| C20 | 990-1006 | NP | denotes | the Bcl-2 family |
| C21 | 1008-1010 | NP | denotes | it |
| C22 | 1022-1049 | NP | denotes | a 9 amino acid domain (BH3) |
| C23 | 1055-1066 | NP | denotes | Bax and Bak |
| C24 | 1067-1072 | NP | denotes | which |
| C25 | 1139-1153 | NP | denotes | these proteins |
| R1 | C2 | C1 | coref-appos | a novel death-inducing protein,Bik |
| R2 | C4 | C3 | coref-ident | the Bcl-2 family of proteins,Bcl-2 family proteins |
| R3 | C7 | C6 | coref-appos | Bik,a novel cellular protein |
| R4 | C8 | C6 | coref-relat | that,a novel cellular protein |
| R5 | C10 | C9 | coref-appos | Bcl-2 and Bcl-xL,the cellular survival-promoting proteins |
| R6 | C12 | C11 | coref-appos | Epstein Barr virus-BHRF1 and adenovirus E1B-19 kDa,the viral survival-promoting proteins |
| R7 | C5 | C1 | coref-ident | "a novel cellular protein, Bik, that interacts with the cellular survival-promoting proteins, Bcl-2 and Bcl-xL, as well as the viral survival-promoting proteins, Epstein Barr virus-BHRF1 and adenovirus E1B-19 kDa",Bik |
| R8 | C13 | C5 | coref-ident | Bik,"a novel cellular protein, Bik, that interacts with the cellular survival-promoting proteins, Bcl-2 and Bcl-xL, as well as the viral survival-promoting proteins, Epstein Barr virus-BHRF1 and adenovirus E1B-19 kDa" |
| R9 | C15 | C4 | coref-ident | the Bcl-2 family,the Bcl-2 family of proteins |
| R10 | C16 | C14 | coref-appos | Bax and Bak,"the death-promoting members of the Bcl-2 family, Bax and Bak" |
| R11 | C17 | C13 | coref-ident | Bik,Bik |
| R12 | C18 | C17 | coref-ident | Bik,Bik |
| R13 | C19 | C18 | coref-ident | Bik,Bik |
| R14 | C20 | C15 | coref-ident | the Bcl-2 family,the Bcl-2 family |
| R15 | C21 | C19 | coref-pron | it,Bik |
| R16 | C23 | C14 | coref-ident | Bax and Bak,"the death-promoting members of the Bcl-2 family, Bax and Bak" |
| R17 | C24 | C22 | coref-relat | which,a 9 amino acid domain (BH3) |
| R18 | C25 | C23 | coref-ident | these proteins,Bax and Bak |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-162 | Sentence | denotes | Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. |
| S2 | 163-301 | Sentence | denotes | The survival-promoting activity of the Bcl-2 family of proteins appears to be modulated by interactions between various cellular proteins. |
| S3 | 302-533 | Sentence | denotes | We have identified a novel cellular protein, Bik, that interacts with the cellular survival-promoting proteins, Bcl-2 and Bcl-xL, as well as the viral survival-promoting proteins, Epstein Barr virus-BHRF1 and adenovirus E1B-19 kDa. |
| S4 | 534-676 | Sentence | denotes | In transient transfection assays, Bik promotes cell death in a manner similar to the death-promoting members of the Bcl-2 family, Bax and Bak. |
| S5 | 677-895 | Sentence | denotes | This death-promoting activity of Bik can be suppressed by coexpression of Bcl-2, Bcl-XL, EBV-BHRF1 and E1B-19 kDa proteins suggesting that Bik may be a common target for both cellular and viral anti-apoptotic proteins. |
| S6 | 896-1154 | Sentence | denotes | While Bik does not show overt homology to the BH1 and BH2 conserved domains characteristic of the Bcl-2 family, it does share a 9 amino acid domain (BH3) with Bax and Bak which may be a critical determinant for the death-promoting activity of these proteins. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-3 | protein_molecule | denotes | Bik |
| T2 | 13-35 | protein_family_or_group | denotes | death-inducing protein |
| T3 | 74-95 | protein_family_or_group | denotes | Bcl-2 family proteins |
| T4 | 125-161 | protein_family_or_group | denotes | cellular survival-promoting proteins |
| T5 | 167-194 | other_name | denotes | survival-promoting activity |
| T6 | 202-214 | protein_family_or_group | denotes | Bcl-2 family |
| T7 | 283-300 | protein_family_or_group | denotes | cellular proteins |
| T8 | 329-345 | protein_family_or_group | denotes | cellular protein |
| T9 | 347-350 | protein_molecule | denotes | Bik |
| T10 | 376-412 | protein_family_or_group | denotes | cellular survival-promoting proteins |
| T11 | 414-419 | protein_molecule | denotes | Bcl-2 |
| T12 | 424-430 | protein_molecule | denotes | Bcl-xL |
| T13 | 447-480 | protein_family_or_group | denotes | viral survival-promoting proteins |
| T14 | 482-500 | virus | denotes | Epstein Barr virus |
| T15 | 511-521 | virus | denotes | adenovirus |
| T16 | 537-566 | other_name | denotes | transient transfection assays |
| T17 | 568-571 | protein_molecule | denotes | Bik |
| T18 | 581-591 | other_name | denotes | cell death |
| T19 | 619-642 | protein_family_or_group | denotes | death-promoting members |
| T20 | 650-655 | protein_molecule | denotes | Bcl-2 |
| T21 | 664-667 | protein_molecule | denotes | Bax |
| T22 | 672-675 | protein_molecule | denotes | Bak |
| T23 | 710-713 | protein_molecule | denotes | Bik |
| T24 | 735-747 | other_name | denotes | coexpression |
| T25 | 751-756 | protein_molecule | denotes | Bcl-2 |
| T26 | 758-764 | protein_family_or_group | denotes | Bcl-XL |
| T27 | 766-775 | protein_molecule | denotes | EBV-BHRF1 |
| T28 | 780-790 | protein_molecule | denotes | E1B-19 kDa |
| T29 | 816-819 | protein_molecule | denotes | Bik |
| T30 | 902-905 | protein_molecule | denotes | Bik |
| T31 | 942-945 | protein_molecule | denotes | BH1 |
| T32 | 950-953 | protein_molecule | denotes | BH2 |
| T33 | 994-1006 | protein_family_or_group | denotes | Bcl-2 family |
| T34 | 1026-1043 | protein_domain_or_region | denotes | amino acid domain |
| T35 | 1045-1048 | protein_molecule | denotes | BH3 |
| T36 | 1055-1058 | protein_molecule | denotes | Bax |
| T37 | 1063-1066 | protein_molecule | denotes | Bak |
| T38 | 1111-1135 | other_name | denotes | death-promoting activity |