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PubMed:7437512 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 1494-1500 gene:8266 denotes G-6-PD
T1 1486-1489 disease:C0043194 denotes WAS
T2 1494-1500 gene:2539 denotes G-6-PD
T3 1486-1489 disease:C0043194 denotes WAS
R1 T0 T1 associated_with G-6-PD,WAS
R2 T2 T3 associated_with G-6-PD,WAS

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-91 Sentence denotes Wiskott-Aldrich syndrome: cellular impairments and their implication for carrier detection.
TextSentencer_T2 92-297 Sentence denotes A family in which two male siblings were affected with Wiskott-Aldrich syndrome (WAS) was studied using G-6-PD isoenzymes as an X-linked marker in order to investigate the nature of cellular abnormalities.
TextSentencer_T3 298-541 Sentence denotes Isolated peripheral blood cell types from the doubly heterozygous mother of the affected males seemingly failed to express the G-6-PD allele in cis position with the WAS allele while her cultured skin fibroblasts expressed both G-6-PD alleles.
TextSentencer_T4 542-761 Sentence denotes Additionally, a histogram analysis of platelet size revealed a single population of abnormally small platelets in the affected propositus, whereas the heterozygous mother had no appreciable small platelet subpopulation.
TextSentencer_T5 762-914 Sentence denotes In vitro culture of hemopoietic progenitor cells of the heterozygous mother showed that the majority of progenitor cells did not express the WAS allele.
TextSentencer_T6 915-1016 Sentence denotes However, a small number of cells expressing the G-6-PD type linked with the WAS allele were detected.
TextSentencer_T7 1017-1164 Sentence denotes The proportion of the latter progenitors was significantly higher among more primitive progenitors (those giving rise to later appearing colonies).
TextSentencer_T8 1165-1386 Sentence denotes This observation suggests that selection against cells expressing the Wiskott-Aldrich defect takes place in the hemopoietic system of the heterozygous female and offers a possible means of carrier detection in some women.
TextSentencer_T9 1387-1612 Sentence denotes Linkage studies in this family revealed one example of probable recombination between the loci for WAS and G-6-PD among three informative subjects, suggesting that these two loci may not be closely linked on the X-chromosome.
T1 0-91 Sentence denotes Wiskott-Aldrich syndrome: cellular impairments and their implication for carrier detection.
T2 92-297 Sentence denotes A family in which two male siblings were affected with Wiskott-Aldrich syndrome (WAS) was studied using G-6-PD isoenzymes as an X-linked marker in order to investigate the nature of cellular abnormalities.
T3 298-541 Sentence denotes Isolated peripheral blood cell types from the doubly heterozygous mother of the affected males seemingly failed to express the G-6-PD allele in cis position with the WAS allele while her cultured skin fibroblasts expressed both G-6-PD alleles.
T4 542-761 Sentence denotes Additionally, a histogram analysis of platelet size revealed a single population of abnormally small platelets in the affected propositus, whereas the heterozygous mother had no appreciable small platelet subpopulation.
T5 762-914 Sentence denotes In vitro culture of hemopoietic progenitor cells of the heterozygous mother showed that the majority of progenitor cells did not express the WAS allele.
T6 915-1016 Sentence denotes However, a small number of cells expressing the G-6-PD type linked with the WAS allele were detected.
T7 1017-1164 Sentence denotes The proportion of the latter progenitors was significantly higher among more primitive progenitors (those giving rise to later appearing colonies).
T8 1165-1386 Sentence denotes This observation suggests that selection against cells expressing the Wiskott-Aldrich defect takes place in the hemopoietic system of the heterozygous female and offers a possible means of carrier detection in some women.
T9 1387-1612 Sentence denotes Linkage studies in this family revealed one example of probable recombination between the loci for WAS and G-6-PD among three informative subjects, suggesting that these two loci may not be closely linked on the X-chromosome.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 318-323 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

PubCasesORDO

Id Subject Object Predicate Lexical cue
TI1 0-24 ORDO:906 denotes Wiskott-Aldrich syndrome
AB1 147-171 ORDO:906 denotes Wiskott-Aldrich syndrome

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 318-323 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

NCBIDiseaseCorpus

Id Subject Object Predicate Lexical cue
T1 0-24 SpecificDisease:D014923 denotes Wiskott-Aldrich syndrome
T2 147-171 SpecificDisease:D014923 denotes Wiskott-Aldrich syndrome
T3 173-176 SpecificDisease:D014923 denotes WAS
T4 464-467 Modifier:D014923 denotes WAS
T5 903-906 Modifier:D014923 denotes WAS
T6 991-994 Modifier:D014923 denotes WAS
T7 1235-1257 SpecificDisease:D014923 denotes Wiskott-Aldrich defect
T8 1486-1489 SpecificDisease:D014923 denotes WAS

NCBI-Disease-Train

Id Subject Object Predicate Lexical cue database_id
T3670 0-24 SpecificDisease denotes Wiskott-Aldrich syndrome D014923
T3671 147-171 SpecificDisease denotes Wiskott-Aldrich syndrome D014923
T3672 173-176 SpecificDisease denotes WAS D014923
T3673 464-467 Modifier denotes WAS D014923
T3674 903-906 Modifier denotes WAS D014923
T3675 991-994 Modifier denotes WAS D014923
T3676 1235-1257 SpecificDisease denotes Wiskott-Aldrich defect D014923
T3677 1486-1489 SpecificDisease denotes WAS D014923

NCBI-Disease-Corpus-All

Id Subject Object Predicate Lexical cue database_id
T3670 0-24 SpecificDisease denotes Wiskott-Aldrich syndrome D014923
T3671 147-171 SpecificDisease denotes Wiskott-Aldrich syndrome D014923
T3672 173-176 SpecificDisease denotes WAS D014923
T3673 464-467 Modifier denotes WAS D014923
T3674 903-906 Modifier denotes WAS D014923
T3675 991-994 Modifier denotes WAS D014923
T3676 1235-1257 SpecificDisease denotes Wiskott-Aldrich defect D014923
T3677 1486-1489 SpecificDisease denotes WAS D014923

NCBI-Disease-Corpus-2stage-All

Id Subject Object Predicate Lexical cue
T1 147-171 SpecificDisease denotes Wiskott-Aldrich syndrome
T2 173-176 SpecificDisease denotes WAS
T3 464-467 Modifier denotes WAS
T4 903-906 Modifier denotes WAS
T5 991-994 Modifier denotes WAS
T6 1235-1250 Modifier denotes Wiskott-Aldrich
T7 1486-1489 Modifier denotes WAS

NCBI-Disease-Corpus-rezarta-All

Id Subject Object Predicate Lexical cue
T1 147-171 SpecificDisease denotes Wiskott-Aldrich syndrome
T2 173-176 SpecificDisease denotes WAS
T3 464-467 Modifier denotes WAS
T4 903-906 Modifier denotes WAS
T5 991-994 Modifier denotes WAS
T6 1235-1250 Modifier denotes Wiskott-Aldrich
T7 1486-1489 Modifier denotes WAS

NCBI-Disease-Corpus-4oGuideline-All

Id Subject Object Predicate Lexical cue
T1 0-24 SpecificDisease denotes Wiskott-Aldrich syndrome
T2 147-171 SpecificDisease denotes Wiskott-Aldrich syndrome
T3 1235-1250 Modifier denotes Wiskott-Aldrich

NCBI-Disease-Corpus-Simple-All

Id Subject Object Predicate Lexical cue
T1 0-24 SpecificDisease denotes Wiskott-Aldrich syndrome
T2 147-171 SpecificDisease denotes Wiskott-Aldrich syndrome
T3 464-467 SpecificDisease denotes WAS
T4 903-906 SpecificDisease denotes WAS
T5 991-994 SpecificDisease denotes WAS
T6 1235-1257 CompositeMention denotes Wiskott-Aldrich defect
T7 1486-1489 SpecificDisease denotes WAS