PubMed:7407141 JSONTXT

{"project":"Glycan-GlyCosmos","denotations":[{"id":"T1","span":{"begin":469,"end":478},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A2","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}

{"project":"GlyCosmos15-NCBITAXON","denotations":[{"id":"T1","span":{"begin":103,"end":112},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"4547"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T1","span":{"begin":113,"end":122},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/GO_0016020"},{"id":"A2","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000094"},{"id":"A3","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T1","span":{"begin":0,"end":123},"obj":"Sentence"},{"id":"T2","span":{"begin":124,"end":126},"obj":"Sentence"},{"id":"T3","span":{"begin":127,"end":315},"obj":"Sentence"},{"id":"T4","span":{"begin":316,"end":318},"obj":"Sentence"},{"id":"T5","span":{"begin":319,"end":451},"obj":"Sentence"},{"id":"T6","span":{"begin":452,"end":454},"obj":"Sentence"},{"id":"T7","span":{"begin":455,"end":635},"obj":"Sentence"},{"id":"T8","span":{"begin":636,"end":638},"obj":"Sentence"},{"id":"T9","span":{"begin":639,"end":878},"obj":"Sentence"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T1","span":{"begin":469,"end":478},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A2","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":103,"end":112},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"4547"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":113,"end":122},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/GO_0016020"},{"id":"A2","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000094"},{"id":"A3","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"Inverse relationship of protein concentration and binding activity of alpha-galactoside receptors from sugarcane membranes.\n1. The binding activity of purified alpha-galactoside receptor proteins from a number of plant species decreases when the protein concentration is increased from 2 ng/ml to 100 micrograms/ml. 2. The apparent loss of binding activity at high protein concentrations corresonds to the formation of high molecular weight multimers. 3. Raffinose and melibiose cause a ligant-dependent increase in binding activity and a corresponding decrease in the relative abundance of multimers at any give protein concentration. 4. The self-inhibition of binding activity at high protein concentrations arises from a competition between ligant binding by oligomers and self-association of these oligomers into multimeric species which have little or no binding acitivity."}