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PubMed:7354056 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-60 Sentence denotes An NADP-linked prostaglandin D dehydrogenase in swine brain.
T2 61-210 Sentence denotes An NADP-linked 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin D2 was discovered and partially purified from cytosol of swine brain.
T3 211-365 Sentence denotes Prostaglandins A2, B2, D3, E2, and F2 alpha were poor substrates for this enzyme, the rates of reaction being less than 10% of that with prostaglandin D2.
T4 366-603 Sentence denotes The enzyme was separated by Sephadex column chromatography from the other NADP-linked 15-hydroxyprostaglandin dehydrogenase that was also present in brain and metabolized prostaglandins B2, E2, and F2 alpha much more effectively than D2.
T5 604-759 Sentence denotes The primary reaction product was tentatively identified as 15-ketoprostaglandin D2 by its characteristic absorption spectrum with a peak at 415 nm at pH 9.
T6 760-963 Sentence denotes This compound was further converted to 13,14-dihydro-15-ketoprostaglandin D2 in the presence of NADPH by the action of 15-ketoprostaglandin delta 13-reductase that was co-purified with the dehydrogenase.
T7 964-1122 Sentence denotes This dehydrogenase appears to be responsible for the specific inactivation of prostaglandin D2 which is the major prostaglandin in the central nervous system.
T1 0-60 Sentence denotes An NADP-linked prostaglandin D dehydrogenase in swine brain.
T2 61-210 Sentence denotes An NADP-linked 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin D2 was discovered and partially purified from cytosol of swine brain.
T3 211-365 Sentence denotes Prostaglandins A2, B2, D3, E2, and F2 alpha were poor substrates for this enzyme, the rates of reaction being less than 10% of that with prostaglandin D2.
T4 366-603 Sentence denotes The enzyme was separated by Sephadex column chromatography from the other NADP-linked 15-hydroxyprostaglandin dehydrogenase that was also present in brain and metabolized prostaglandins B2, E2, and F2 alpha much more effectively than D2.
T5 604-759 Sentence denotes The primary reaction product was tentatively identified as 15-ketoprostaglandin D2 by its characteristic absorption spectrum with a peak at 415 nm at pH 9.
T6 760-963 Sentence denotes This compound was further converted to 13,14-dihydro-15-ketoprostaglandin D2 in the presence of NADPH by the action of 15-ketoprostaglandin delta 13-reductase that was co-purified with the dehydrogenase.
T7 964-1122 Sentence denotes This dehydrogenase appears to be responsible for the specific inactivation of prostaglandin D2 which is the major prostaglandin in the central nervous system.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 54-59 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T2 204-209 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T3 515-520 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T4 1099-1121 http://purl.obolibrary.org/obo/MAT_0000457 denotes central nervous system
T5 1107-1121 http://purl.obolibrary.org/obo/MAT_0000026 denotes nervous system

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 54-59 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 204-209 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 515-520 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T4 1099-1121 Body_part denotes central nervous system http://purl.obolibrary.org/obo/MAT_0000457

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 48-53 OrganismTaxon denotes swine 9823
T2 198-203 OrganismTaxon denotes swine 9823

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 54-59 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T3 187-194 Body_part denotes cytosol http://purl.obolibrary.org/obo/GO_0005829
T4 204-209 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T6 515-520 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T8 1099-1121 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 900-905 Cell denotes delta http://purl.obolibrary.org/obo/CL:0004124