PubMed:7287761
Annnotations
GlyCosmos15-Species
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 18 | 611-624 | Species | denotes | cholera toxin |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 50-53 | Glycan_Motif | denotes | GM1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI |
| T3 | 301-318 | Glycan_Motif | denotes | glucosyl ceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF |
| T4 | 320-323 | Glycan_Motif | denotes | GM1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI |
| T6 | 628-631 | Glycan_Motif | denotes | GM1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-75 | Sentence | denotes | Lipid insertion of cholera toxin after binding to GM1-containing liposomes. |
| T2 | 76-325 | Sentence | denotes | The technique of hydrophobic photolabeling with photoreactive lipids was used to study the topology of interaction of cholera toxin with liposomes containing galactosyl-N-acetylgalactosaminyl-[N-acetyl neuraminyl]-galactosyl glucosyl ceramide (GM1). |
| T3 | 326-396 | Sentence | denotes | The toxin appears to locate itself superficially on the lipid bilayer. |
| T4 | 397-455 | Sentence | denotes | The interaction is mediated only by the gamma beta 5 part. |
| T5 | 456-590 | Sentence | denotes | On reduction of the disulfide bridge joining the alpha and gamma subunits, the alpha subunit penetrates deeply into the lipid bilayer. |
| T6 | 591-731 | Sentence | denotes | The mere binding of cholera toxin to GM1 is not sufficient to allow the insertion of the enzymatically active alpha subunit in the membrane. |
| T7 | 732-881 | Sentence | denotes | Some processing, which may involve a modification of covalent bonds of the toxin molecule (such as that caused by reduction) appears to be necessary. |
| T8 | 882-1060 | Sentence | denotes | The specific reduction of the alpha-gamma disulfide bond on the external surface of the membrane as a prerequisite for the membrane penetration of the alpha subunit is discussed. |
| T1 | 0-75 | Sentence | denotes | Lipid insertion of cholera toxin after binding to GM1-containing liposomes. |
| T2 | 76-325 | Sentence | denotes | The technique of hydrophobic photolabeling with photoreactive lipids was used to study the topology of interaction of cholera toxin with liposomes containing galactosyl-N-acetylgalactosaminyl-[N-acetyl neuraminyl]-galactosyl glucosyl ceramide (GM1). |
| T3 | 326-396 | Sentence | denotes | The toxin appears to locate itself superficially on the lipid bilayer. |
| T4 | 397-455 | Sentence | denotes | The interaction is mediated only by the gamma beta 5 part. |
| T5 | 456-590 | Sentence | denotes | On reduction of the disulfide bridge joining the alpha and gamma subunits, the alpha subunit penetrates deeply into the lipid bilayer. |
| T6 | 591-731 | Sentence | denotes | The mere binding of cholera toxin to GM1 is not sufficient to allow the insertion of the enzymatically active alpha subunit in the membrane. |
| T7 | 732-881 | Sentence | denotes | Some processing, which may involve a modification of covalent bonds of the toxin molecule (such as that caused by reduction) appears to be necessary. |
| T8 | 882-1060 | Sentence | denotes | The specific reduction of the alpha-gamma disulfide bond on the external surface of the membrane as a prerequisite for the membrane penetration of the alpha subunit is discussed. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-53 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T2 | 50-53 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T3 | 301-318 | https://glytoucan.org/Structures/Glycans/G71142DF | denotes | glucosyl ceramide |
| T4 | 320-323 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T5 | 320-323 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T6 | 628-631 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T7 | 628-631 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-53 | http://www.glycoepitope.jp/epitopes/EP0050 | denotes | GM1 |
| T2 | 320-323 | http://www.glycoepitope.jp/epitopes/EP0050 | denotes | GM1 |
| T3 | 628-631 | http://www.glycoepitope.jp/epitopes/EP0050 | denotes | GM1 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 50-53 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T2 | 320-323 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T3 | 628-631 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 19-26 | Disease | denotes | cholera | http://purl.obolibrary.org/obo/MONDO_0015766 |
| T2 | 194-201 | Disease | denotes | cholera | http://purl.obolibrary.org/obo/MONDO_0015766 |
| T3 | 611-618 | Disease | denotes | cholera | http://purl.obolibrary.org/obo/MONDO_0015766 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 50-53 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T2 | 320-323 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T3 | 628-631 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 50-53 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 320-323 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T3 | 628-631 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 722-730 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T4 | 970-978 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T7 | 1005-1013 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 50-53 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 320-323 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T3 | 628-631 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-75 | Sentence | denotes | Lipid insertion of cholera toxin after binding to GM1-containing liposomes. |
| T2 | 76-325 | Sentence | denotes | The technique of hydrophobic photolabeling with photoreactive lipids was used to study the topology of interaction of cholera toxin with liposomes containing galactosyl-N-acetylgalactosaminyl-[N-acetyl neuraminyl]-galactosyl glucosyl ceramide (GM1). |
| T3 | 326-396 | Sentence | denotes | The toxin appears to locate itself superficially on the lipid bilayer. |
| T4 | 397-455 | Sentence | denotes | The interaction is mediated only by the gamma beta 5 part. |
| T5 | 456-590 | Sentence | denotes | On reduction of the disulfide bridge joining the alpha and gamma subunits, the alpha subunit penetrates deeply into the lipid bilayer. |
| T6 | 591-731 | Sentence | denotes | The mere binding of cholera toxin to GM1 is not sufficient to allow the insertion of the enzymatically active alpha subunit in the membrane. |
| T7 | 732-881 | Sentence | denotes | Some processing, which may involve a modification of covalent bonds of the toxin molecule (such as that caused by reduction) appears to be necessary. |
| T8 | 882-1060 | Sentence | denotes | The specific reduction of the alpha-gamma disulfide bond on the external surface of the membrane as a prerequisite for the membrane penetration of the alpha subunit is discussed. |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 19-26 | Disease | denotes | cholera | MONDO:0015766 |
| T2 | 194-201 | Disease | denotes | cholera | MONDO:0015766 |
| T3 | 611-618 | Disease | denotes | cholera | MONDO:0015766 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 722-730 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T4 | 970-978 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T7 | 1005-1013 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |