PubMed:7197363 JSONTXT

{"project":"bc5cdr-valid-experiment","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"Disease"},{"id":"T2","span":{"begin":132,"end":153},"obj":"Disease"},{"id":"T3","span":{"begin":155,"end":159},"obj":"Disease"},{"id":"T4","span":{"begin":164,"end":175},"obj":"Chemical"},{"id":"T5","span":{"begin":184,"end":198},"obj":"Disease"},{"id":"T6","span":{"begin":203,"end":212},"obj":"Chemical"},{"id":"T7","span":{"begin":221,"end":234},"obj":"Disease"},{"id":"T8","span":{"begin":278,"end":282},"obj":"Disease"},{"id":"T9","span":{"begin":293,"end":304},"obj":"Chemical"},{"id":"T10","span":{"begin":313,"end":327},"obj":"Disease"},{"id":"T11","span":{"begin":374,"end":378},"obj":"Disease"},{"id":"T12","span":{"begin":420,"end":424},"obj":"Disease"},{"id":"T13","span":{"begin":426,"end":435},"obj":"Chemical"},{"id":"T14","span":{"begin":444,"end":457},"obj":"Disease"}],"text":"REM sleep deprivation changes behavioral response to catecholaminergic and serotonergic receptor activation in rats.\nThe effects of REM sleep deprivation (REMD) on apomorphine-induced aggressiveness and quipazine-induced head twitches in rats were determined. Forty-eight hr of REMD increased apomorphine-induced aggressiveness, and reduced (immediately after completing of REMD) or increased (96 hr after completing of REMD) quipazine-induced head twitches. Results are discussed in terms of similarity to pharmacological effects of other antidepressive treatments."}