PubMed:7047530 JSONTXT

{"project":"sentences","denotations":[{"id":"T1","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T2","span":{"begin":79,"end":209},"obj":"Sentence"},{"id":"T3","span":{"begin":210,"end":296},"obj":"Sentence"},{"id":"T4","span":{"begin":297,"end":434},"obj":"Sentence"},{"id":"T5","span":{"begin":435,"end":671},"obj":"Sentence"},{"id":"T6","span":{"begin":672,"end":766},"obj":"Sentence"},{"id":"T7","span":{"begin":767,"end":929},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T2","span":{"begin":79,"end":209},"obj":"Sentence"},{"id":"T3","span":{"begin":210,"end":296},"obj":"Sentence"},{"id":"T4","span":{"begin":297,"end":434},"obj":"Sentence"},{"id":"T5","span":{"begin":435,"end":671},"obj":"Sentence"},{"id":"T6","span":{"begin":672,"end":766},"obj":"Sentence"},{"id":"T7","span":{"begin":767,"end":929},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T1","span":{"begin":27,"end":36},"obj":"Glycan"},{"id":"T2","span":{"begin":189,"end":198},"obj":"Glycan"},{"id":"T3","span":{"begin":276,"end":285},"obj":"Glycan"},{"id":"T4","span":{"begin":424,"end":433},"obj":"Glycan"},{"id":"T5","span":{"begin":474,"end":483},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A6","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A2","pred":"glycosmos_id","subj":"T2","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A7","pred":"image","subj":"T2","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A3","pred":"glycosmos_id","subj":"T3","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A8","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A4","pred":"glycosmos_id","subj":"T4","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A9","pred":"image","subj":"T4","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A5","pred":"glycosmos_id","subj":"T5","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A10","pred":"image","subj":"T5","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"Glycan-GlyCosmos","denotations":[{"id":"T1","span":{"begin":27,"end":36},"obj":"Glycan"},{"id":"T2","span":{"begin":189,"end":198},"obj":"Glycan"},{"id":"T3","span":{"begin":276,"end":285},"obj":"Glycan"},{"id":"T4","span":{"begin":424,"end":433},"obj":"Glycan"},{"id":"T5","span":{"begin":474,"end":483},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A6","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A2","pred":"glycosmos_id","subj":"T2","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A7","pred":"image","subj":"T2","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A3","pred":"glycosmos_id","subj":"T3","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A8","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A4","pred":"glycosmos_id","subj":"T4","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A9","pred":"image","subj":"T4","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"},{"id":"A5","pred":"glycosmos_id","subj":"T5","obj":"https://glycosmos.org/glycans/show/G66481II"},{"id":"A10","pred":"image","subj":"T5","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T1","span":{"begin":661,"end":670},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000468"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"GlyCosmos15-Taxon","denotations":[{"id":"T1","span":{"begin":61,"end":77},"obj":"Organism"},{"id":"T2","span":{"begin":121,"end":137},"obj":"Organism"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"562"},{"id":"A2","pred":"db_id","subj":"T2","obj":"562"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T1","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T2","span":{"begin":79,"end":209},"obj":"Sentence"},{"id":"T3","span":{"begin":210,"end":296},"obj":"Sentence"},{"id":"T4","span":{"begin":297,"end":434},"obj":"Sentence"},{"id":"T5","span":{"begin":435,"end":671},"obj":"Sentence"},{"id":"T6","span":{"begin":672,"end":766},"obj":"Sentence"},{"id":"T7","span":{"begin":767,"end":929},"obj":"Sentence"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":61,"end":77},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":121,"end":137},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"562"},{"id":"A2","pred":"db_id","subj":"T2","obj":"562"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":661,"end":670},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000468"}],"text":"Altered cation coupling to melibiose transport in mutants of Escherichia coli.\nThe alpha-galactoside transport system of Escherichia coli utilizes either H+ of Na+ as a coupling cation for melibiose transport. Mutants were isolated which showed altered cation recognition for melibiose transport. The transport carrier of the mutants has lost the ability to accept H+ but can utilize either Na/ or Li+ for co-transport with melibiose. Such mutants might be predicted if the melibiose carrier were viewed as a descendant of an evolutionary transition between the H+-substrate co-transport systems of primitive cells and the Na+-substrate systems of more complex organisms. A second mutation was found in these mutants which involves the Na+ (Li+)-H+ exchange carrier. The maximal rate of Li+-H+ exchange in one of the mutants was 11 times higher than the parent and the Km for Li+ by this carrier was one-sixth that of the parent."}