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PubMed:6948579 JSONTXT

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Test-Species-PubTator

Id Subject Object Predicate Lexical cue resolved_to
2 53-68 Gene denotes casein kinase I 58822
3 74-77 Species denotes rat 10116
31 176-185 Gene denotes phosvitin 81650
32 210-213 Species denotes rat 10116
33 357-372 Gene denotes casein kinase I 58822
34 527-549 Chemical denotes carboxymethyl-Sephadex -
35 551-560 Gene denotes phosvitin 81650
36 561-570 Chemical denotes Sepharose MESH:D012685
37 575-589 Chemical denotes hydroxyapatite MESH:D017886
38 736-743 Chemical denotes sucrose MESH:D013395
39 798-813 Chemical denotes [gamma- 32P]ATP -
40 834-848 Chemical denotes polyacrylamide MESH:C016679
41 872-894 Chemical denotes sodium dodecyl sulfate MESH:D012967
42 896-899 Chemical denotes SDS MESH:D012967
43 1039-1054 Gene denotes casein kinase I 58822
44 1079-1082 Chemical denotes ATP MESH:D000255
45 1088-1091 Chemical denotes GTP MESH:D006160
46 1110-1113 Chemical denotes ATP MESH:D000255
47 1164-1173 Gene denotes phosvitin 81650
48 1190-1205 Gene denotes Casein kinase I 58822
49 1313-1328 Gene denotes Casein kinase I 58822
50 1495-1498 Chemical denotes ATP MESH:D000255
51 1503-1512 Gene denotes phosvitin 81650
52 1637-1652 Gene denotes casein kinase I 58822
53 1714-1730 Chemical denotes N-ethylmaleimide MESH:D005033
54 1748-1764 Gene denotes casein kinase I. 58822
55 1765-1774 Gene denotes Phosvitin 81650
56 1787-1790 Chemical denotes ATP MESH:D000255
57 1849-1855 Chemical denotes thiols MESH:D013438

Test-Species-PubDictionaries

Id Subject Object Predicate Lexical cue db_id
T1 74-77 OrganismTaxon denotes rat 10114|10116
T3 210-213 OrganismTaxon denotes rat 10114|10116

Test-Species-PubDictionaries-PubMedBERT

Id Subject Object Predicate Lexical cue db_id
T1 74-77 Species denotes rat 10114|10116
T3 210-213 Species denotes rat 10114|10116
T5 1731-1735 Species denotes also 209674

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 78-83 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T2 214-219 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1301-1310 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1301-1310 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1301-1310 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 41-52 Body_part denotes cytoplasmic http://purl.obolibrary.org/obo/GO_0005737
T2 78-83 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T3 214-219 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T4 236-243 Body_part denotes cytosol http://purl.obolibrary.org/obo/GO_0005829
T5 680-687 Body_part denotes cytosol http://purl.obolibrary.org/obo/GO_0005829
T6 1283-1292 Body_part denotes ribosomes http://purl.obolibrary.org/obo/GO_0005840

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 74-77 Organism denotes rat 10114|10116
T3 210-213 Organism denotes rat 10114|10116

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-84 Sentence denotes Purification and characterization of the cytoplasmic casein kinase I from rat liver.
T2 85-220 Sentence denotes Two cyclic nucleotide-independent protein kinases, which preferentially utilize casein and phosvitin as substrates, exist in rat liver.
T3 221-322 Sentence denotes In contrast to cytosol the "light' form of these enzymes was predominant in the "microsomal extract'.
T4 323-464 Sentence denotes This form (30 000-40 000 daltons, casein kinase I) was separated from the "heavy' form (130 000 daltons, casein kinase II) by gel filtration.
T5 465-590 Sentence denotes This enzyme was then purified by successive chromatography on carboxymethyl-Sephadex, phosvitin-Sepharose and hydroxyapatite.
T6 591-688 Sentence denotes The activity of the purified enzyme was 2000-3000-fold the casein kinase activity of the cytosol.
T7 689-714 Sentence denotes It had a s20,w of approx.
T8 715-761 Sentence denotes 3 S as determined on sucrose density gradient.
T9 762-1005 Sentence denotes After iodination or incubation with [gamma- 32P]ATP, it was analyzed on polyacrylamide gel in the presence of sodium dodecyl sulfate (SDS) and appeared to be composed of a single polypeptide (36 000 +/- 1000 daltons) which self-phosphorylated.
T10 1006-1092 Sentence denotes In contrast to casein kinase II, casein kinase I preferentially utilized ATP over GTP.
T11 1093-1189 Sentence denotes The Km value for ATP was determined to be 14 micro M. The Km value for phosvitin was 0.17 mg/ml.
T12 1190-1312 Sentence denotes Casein kinase I phosphorylated sites different from those of casein kinase II (as shown with ribosomes or SV40 T antigen).
T13 1313-1389 Sentence denotes Casein kinase I was further characterized by studying its thermal stability.
T14 1390-1579 Sentence denotes The half-life at 37 degree C was 6 min and 1 min 30 s at 54 degree C. In the presence of two substrates (ATP and phosvitin), the half-life at 54 degree C increased from 1 min 30 s to 4 min.
T15 1580-1713 Sentence denotes Hemin strongly increased the rate of inactivation of the casein kinase I at 37 degree C in the absence or presence of the substrates.
T16 1714-1813 Sentence denotes N-ethylmaleimide also inactivated casein kinase I. Phosvitin, though not ATP, protected the enzyme.
T17 1814-1929 Sentence denotes This observation may indicate that thiols are involved at the binding site of the enzyme for the protein substrate.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1301-1310 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 41-52 Body_part denotes cytoplasmic FMA:66835
T2 78-83 Body_part denotes liver FMA:7197
T3 214-219 Body_part denotes liver FMA:7197
T4 236-243 Body_part denotes cytosol FMA:66836
T5 302-312 Body_part denotes microsomal FMA:67438
T6 680-687 Body_part denotes cytosol FMA:66836
T7 1283-1292 Body_part denotes ribosomes FMA:66867

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 78-83 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T2 214-219 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 74-77 OrganismTaxon denotes rat 10114|10116
T3 210-213 OrganismTaxon denotes rat 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 41-52 Body_part denotes cytoplasmic http://purl.obolibrary.org/obo/GO_0005737
T2 78-83 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T3 214-219 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T4 236-243 Body_part denotes cytosol http://purl.obolibrary.org/obo/GO_0005829
T5 680-687 Body_part denotes cytosol http://purl.obolibrary.org/obo/GO_0005829
T6 1283-1292 Body_part denotes ribosomes http://purl.obolibrary.org/obo/GO_0005840