PubMed:6896661
Annnotations
Test-Species-PubTator
| Id | Subject | Object | Predicate | Lexical cue | resolved_to |
|---|---|---|---|---|---|
| 2 | 15-46 | Gene | denotes | simian virus 40 large T antigen | |
| 3 | 54-67 | Chemical | denotes | polyphosphate | MESH:D011122 |
| 33 | 95-137 | Gene | denotes | Simian virus 40 (SV40) large tumor antigen | |
| 34 | 139-148 | Gene | denotes | T antigen | |
| 35 | 305-314 | Gene | denotes | T antigen | |
| 36 | 364-377 | Chemical | denotes | DNA-cellulose | MESH:C033190 |
| 37 | 392-408 | Chemical | denotes | phosphocellulose | MESH:C008881 |
| 38 | 444-460 | Chemical | denotes | [35S] methionine | - |
| 39 | 464-476 | Chemical | denotes | [3H] leucine | - |
| 40 | 477-493 | Chemical | denotes | [32 P] phosphate | - |
| 41 | 582-598 | Chemical | denotes | phosphocellulose | MESH:C008881 |
| 42 | 629-638 | Gene | denotes | T antigen | |
| 43 | 669-672 | Chemical | denotes | SDS | MESH:D012967 |
| 44 | 673-687 | Chemical | denotes | polyacrylamide | MESH:C016679 |
| 45 | 786-796 | Gene | denotes | T antigens | |
| 46 | 844-857 | Chemical | denotes | DNA-cellulose | MESH:C033190 |
| 47 | 862-878 | Chemical | denotes | phosphocellulose | MESH:C008881 |
| 48 | 917-926 | Gene | denotes | T antigen | |
| 49 | 934-947 | Chemical | denotes | polyphosphate | MESH:D011122 |
| 50 | 1093-1102 | Gene | denotes | T antigen | |
| 51 | 1106-1119 | Chemical | denotes | DNA-cellulose | MESH:C033190 |
| 52 | 1142-1146 | Chemical | denotes | a2+, | - |
| 53 | 1148-1152 | Chemical | denotes | g2+) | - |
| 54 | 1155-1157 | Chemical | denotes | H/ | MESH:D014316 |
| 55 | 1158-1161 | Chemical | denotes | 2P | MESH:C000615311 |
| 56 | 1172-1181 | Gene | denotes | antigen | |
| 57 | 1276-1285 | Gene | denotes | antigen | |
| 58 | 1338-1354 | Chemical | denotes | hosphocellulose. | MESH:C008881 |
| 59 | 1444-1453 | Gene | denotes | antigen | |
| 60 | 1461-1474 | Chemical | denotes | olyphosphate | MESH:D011122 |
| 61 | 1636-1650 | Gene | denotes | V40 T antigen |
Test-Species-PubDictionaries
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 15-30 | OrganismTaxon | denotes | simian virus 40 | 1891767 |
| T2 | 95-110 | OrganismTaxon | denotes | Simian virus 40 | 1891767 |
| T3 | 112-116 | OrganismTaxon | denotes | SV40 | 1891767 |
| T4 | 187-191 | OrganismTaxon | denotes | SV40 | 1891767 |
| T5 | 1635-1639 | OrganismTaxon | denotes | SV40 | 1891767 |
Test-Species-PubDictionaries-PubMedBERT
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 15-30 | Species | denotes | simian virus 40 | 1891767 |
| T2 | 95-110 | Species | denotes | Simian virus 40 | 1891767 |
| T3 | 112-116 | Species | denotes | SV40 | 1891767 |
| T4 | 187-191 | Species | denotes | SV40 | 1891767 |
| T5 | 1635-1639 | Species | denotes | SV40 | 1891767 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 124-129 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 37-46 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T2 | 139-148 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T3 | 305-314 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T4 | 629-638 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T5 | 917-926 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T6 | 1093-1102 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T7 | 1171-1180 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T8 | 1275-1284 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T9 | 1443-1452 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T10 | 1640-1649 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 37-46 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T2 | 139-148 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T3 | 305-314 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T4 | 629-638 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T5 | 917-926 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T6 | 1093-1102 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T7 | 1171-1180 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T8 | 1275-1284 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T9 | 1443-1452 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T10 | 1640-1649 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 124-129 | Phenotype | denotes | tumor | HP:0002664 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 124-129 | Disease | denotes | tumor | MONDO:0005070 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 15-30 | Organism | denotes | simian virus 40 | 1891767 |
| T2 | 95-110 | Organism | denotes | Simian virus 40 | 1891767 |
| T3 | 112-116 | Organism | denotes | SV40 | 1891767 |
| T4 | 187-191 | Organism | denotes | SV40 | 1891767 |
| T5 | 1635-1639 | Organism | denotes | SV40 | 1891767 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-94 | Sentence | denotes | The binding of simian virus 40 large T antigen to the polyphosphate backbone of nucleic acids. |
| T2 | 95-254 | Sentence | denotes | Simian virus 40 (SV40) large tumor antigen (T antigen), a phosphoprotein found in nuclei of SV40-infected and -transformed cells, binds nonspecifically to DNA. |
| T3 | 255-423 | Sentence | denotes | To study this mechanism the binding properties of T antigen to double-stranded (ds) and single-stranded (ss) DNA-cellulose as well as to phosphocellulose were compared. |
| T4 | 424-785 | Sentence | denotes | After incubation of [35S] methionine or [3H] leucine/[32 P] phosphate radioactively-labeled cell extracts at different pH values (6.0, 7.3, 9.0) with DNA- or phosphocellulose, bound and unbound species of T antigen were purified and analyzed by SDS-polyacrylamide gel electrophoresis for both the yield and the possible correlation with protein phosphorylation. |
| T5 | 786-879 | Sentence | denotes | T antigens bound with comparable affinities to ds- and ss-DNA-cellulose and phosphocellulose. |
| T6 | 880-1017 | Sentence | denotes | These results suggest the binding of T antigen to the polyphosphate backbone of DNA as a molecular mechanism for its nonspecific binding. |
| T7 | 1018-1153 | Sentence | denotes | The evidence for this observation was supported by blocking the binding of T antigen to DNA-cellulose by divalent cations (Ca2+, Mg2+). |
| T8 | 1154-1354 | Sentence | denotes | 3H/32P ratios of T antigen obtained by double-labeling cells for various times imply that higher phosphorylated forms of T antigen bound more strongly to ds- and ss-DNA as well as to phosphocellulose. |
| T9 | 1355-1549 | Sentence | denotes | Thus, in the presence of cellular proteins and other components the binding activity of T antigen to the polyphosphate backbone of DNA seems to be positively correlated with its phosphorylation. |
| T10 | 1550-1707 | Sentence | denotes | These observations are consistent with the hypothesis that the binding affinities of SV40 T antigen to host cell DNA may be regulated by its phosphorylation. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 37-46 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T2 | 139-148 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T3 | 305-314 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T4 | 629-638 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T5 | 917-926 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T6 | 1093-1102 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T7 | 1171-1180 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T8 | 1275-1284 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T9 | 1443-1452 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T10 | 1640-1649 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 68-76 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
| T2 | 948-956 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
| T3 | 1474-1482 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 68-76 | Body_part | denotes | backbone | FMA:13478 |
| T2 | 948-956 | Body_part | denotes | backbone | FMA:13478 |
| T3 | 1474-1482 | Body_part | denotes | backbone | FMA:13478 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 15-30 | OrganismTaxon | denotes | simian virus 40 | 1891767 |
| T2 | 95-110 | OrganismTaxon | denotes | Simian virus 40 | 1891767 |
| T3 | 112-116 | OrganismTaxon | denotes | SV40 | 1891767 |
| T4 | 187-191 | OrganismTaxon | denotes | SV40 | 1891767 |
| T5 | 1635-1639 | OrganismTaxon | denotes | SV40 | 1891767 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 37-46 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T2 | 139-148 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T3 | 305-314 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T4 | 629-638 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T5 | 917-926 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T6 | 1093-1102 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T7 | 1171-1180 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T8 | 1275-1284 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T9 | 1443-1452 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T10 | 1640-1649 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 68-76 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
| T2 | 948-956 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
| T3 | 1474-1482 | Body_part | denotes | backbone | http://purl.obolibrary.org/obo/UBERON_0001130 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 124-129 | Phenotype | denotes | tumor | HP:0002664 |